Topical protection against long-wave ultraviolet A.

abstract：:Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sha...

journal_title：Journal of the American Academy of Dermatology

authors： Murrell DF,Daniel BS,Joly P,Borradori L,Amagai M,Hashimoto T,Caux F,Marinovic B,Sinha AA,Hertl M,Bernard P,Sirois D,Cianchini G,Fairley JA,Jonkman MF,Pandya AG,Rubenstein D,Zillikens D,Payne AS,Woodley D,Zambruno

更新日期：2012-03-01 00:00:00

abstract：:Melanomas are rare in patients who have albinism, compared with the frequent occurrence of squamous cell carcinomas and basal cell carcinomas. This report describes amelanotic metastatic melanoma in a 58-year-old Japanese man who had tyrosinase-positive oculocutaneous albinism. A prolonged bleeding time, facioscapuloh...

journal_title：Journal of the American Academy of Dermatology

authors： Ihn H,Nakamura K,Abe M,Furue M,Takehara K,Nakagawa H,Ishibashi Y

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Glial cell line-derived neurotrophic factor (GDNF) and a related family member, neurturin (NTN), and their cognate receptors (GFRalpha-1 and GFRalpha-2, for GDNF and NTN, respectively) are distal members of the transforming growth factor-beta superfamily. They are involved in the control of murine hair folli...

journal_title：Journal of the American Academy of Dermatology

authors： Adly MA,Assaf HA,Pertile P,Hussein MR,Paus R

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Detecting a more advanced stage of the primary melanoma after wide local excision and reconstruction can complicate patient counseling about prognosis, management of surgical margins, and indications for sentinel lymph node biopsy. OBJECTIVE:To identify the frequency of and risk factors associated with upst...

journal_title：Journal of the American Academy of Dermatology

authors： Etzkorn JR,Sharkey JM,Grunyk JW,Shin TM,Sobanko JF,Miller CJ

更新日期：2017-08-01 00:00:00

abstract：:In this third and last part of our review of cutaneous vascular proliferations we include malignant vascular neoplasms and a group of heterogeneous cutaneous neoplasms characterized by a significant vascular component. We also review some disorders that, in our opinion, have been erroneously considered as vascular neo...

journal_title：Journal of the American Academy of Dermatology

authors： Requena L,Sangueza OP

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Knowledge is limited regarding unknown primary Merkel cell carcinoma (UPMCC). OBJECTIVE:We sought to document the characteristics and behavior of UPMCC, and determine the most appropriate treatment. METHODS:A multicenter, retrospective, consecutive study reviewing patients given a diagnosis of UPMCC betwee...

journal_title：Journal of the American Academy of Dermatology

authors： Tarantola TI,Vallow LA,Halyard MY,Weenig RH,Warschaw KE,Weaver AL,Roenigk RK,Brewer JD,Otley CC

更新日期：2013-03-01 00:00:00

abstract：:In addition to being recognized as a chronic inflammatory disease that manifests in the skin, psoriasis is increasingly understood to be a systemic disease that causes immune dysregulation throughout the body. The systemic nature of psoriasis is evidenced by the higher burden of comorbidities and shorter life expectan...

journal_title：Journal of the American Academy of Dermatology

authors： Lockshin B,Balagula Y,Merola JF

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that the atopy patch test (APT) may make oral challenge superfluous in diagnosing children with food hypersensitivity. OBJECTIVE:To investigate the clinical relevance of APT in predicting hypersensitivity to cow's milk and hen's egg in 486 unselected children 3 years of age. ...

journal_title：Journal of the American Academy of Dermatology

authors： Osterballe M,Andersen KE,Bindslev-Jensen C

更新日期：2004-10-01 00:00:00

abstract：:We describe a patient with vitamin A deficiency phrynoderma caused by a combination of inadequate dietary intake of vitamin A and beta-carotene and malabsorption secondary to primary visceral myopathy and total colectomy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bleasel NR,Stapleton KM,Lee MS,Sullivan J

更新日期：1999-08-01 00:00:00

abstract：:Multiple studies have shown that dermoscopy increases the sensitivity and specificity for the detection of skin cancers compared with examination by the naked eye. Dermoscopy can also lead to the detection of thinner and smaller cancers. In addition, dermoscopy leads to the more precise selection of lesions requiring ...

journal_title：Journal of the American Academy of Dermatology

authors： Yélamos O,Braun RP,Liopyris K,Wolner ZJ,Kerl K,Gerami P,Marghoob AA

更新日期：2019-02-01 00:00:00

abstract：:The standard definition of itching (as "an unpleasant sensation that provokes the desire to scratch") takes no account of recent advances in knowledge about itch physiology. Always imprecise, this definition is also out-of-date. Its defects are discussed in this article, and some modifications are proposed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Savin JA

更新日期：1998-08-01 00:00:00

abstract：:Pityriasis rosea is an acute, self-healing exanthem characterized by oval erythematous-squamous lesions of the trunk and limbs, that usually spares face, scalp, palms, and soles. Constitutional symptoms, which have the character of true prodromes; clinical features, which resemble those of the known exanthems; and man...

journal_title：Journal of the American Academy of Dermatology

authors： Drago F,Broccolo F,Rebora A

更新日期：2009-08-01 00:00:00

abstract：:Sweet's syndrome (SS) occurs most commonly in association with inflammatory or neoplastic disorders. Only rarely has it been associated with immunodeficiency disorders. We describe a child with a T-cell immunodeficiency who had a persistent neutrophilic dermatosis that was histologically and clinically consistent with...

journal_title：Journal of the American Academy of Dermatology

authors： Lipp KE,Shenefelt PD,Nelson RP Jr,Messina JL,Fenske NA

更新日期：1999-05-01 00:00:00

abstract：:Skin cancer is less prevalent in people of color than in the white population. However, when skin cancer occurs in non-whites, it often presents at a more advanced stage, and thus the prognosis is worse compared with white patients. The increased morbidity and mortality associated with skin cancer in patients of color...

journal_title：Journal of the American Academy of Dermatology

authors： Agbai ON,Buster K,Sanchez M,Hernandez C,Kundu RV,Chiu M,Roberts WE,Draelos ZD,Bhushan R,Taylor SC,Lim HW

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Necrolytic migratory erythema (NME) is an uncommon inflammatory dermatosis with a distinct clinical and histologic appearance. NME is usually associated with glucagonoma. Only a few cases of NME in the absence of glucagonoma have been previously reported. OBJECTIVE:We sought to understand further the pathog...

journal_title：Journal of the American Academy of Dermatology

authors： Marinkovich MP,Botella R,Datloff J,Sangueza OP

更新日期：1995-04-01 00:00:00

abstract：:Twenty percent of Americans will be over age 65 by 2030,1 and without a dedicated geriatrics curriculum in many residency trainings programs, dermatologists may be less familiar with age-associated side effects of common dermatologic medications. Herein, we provide a practical guide and clinical safety pearls for the ...

journal_title：Journal of the American Academy of Dermatology

authors： Grinnell M,Price KN,Shah A,Butler D

更新日期：2021-01-16 00:00:00

abstract：:A unique, progressive syndrome of muscle weakness, ascending telangiectasia, and venous ectasia of the legs developed in a 55-year-old woman with autoimmune thyroiditis. Myopathy was documented by electromyography and electron microscopy. Her constellation of findings is considered to be of autoimmune origin. Treatmen...

journal_title：Journal of the American Academy of Dermatology

authors： Shelley WB,Shelley ED

更新日期：1989-11-01 00:00:00

abstract：:In recent years, our understanding of adipose tissue physiology and function has undergone an enormous transformation. Once considered a passive storage receptacle with a fixed number of cells and limited purpose, adipose tissue is now recognized as a complicated organ with important endocrine and metabolic functions....

journal_title：Journal of the American Academy of Dermatology

authors： Avram MM,Avram AS,James WD

更新日期：2005-10-01 00:00:00

abstract：:The analysis of population-specific human leukocyte antigen (HLA) haplotypes has provided evidence that susceptibility to psoriasis is linked to the class I and II major histo-compatibility complex on human chromosome 6. In addition, these studies show that psoriasis consists of two distinct disease subtypes (type I a...

journal_title：Journal of the American Academy of Dermatology

authors： Henseler T

更新日期：1997-08-01 00:00:00

abstract：:We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associat...

journal_title：Journal of the American Academy of Dermatology

authors： Horn KB,Horn MA,Swan J,Singhal S,Guitart J

更新日期：2004-08-01 00:00:00

abstract：:The number of cases of mycotic infections are increasing, presenting physicians today with an unprecedented challenge in handling the treatment and prophylactic control of these disorders. The increase in mycotic disorders is due to many factors, such as longer life span, organ transplantation, and the acquired immuno...

journal_title：Journal of the American Academy of Dermatology

authors： Jacobs PH

更新日期：1990-09-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is regarded as a disorder of histiocytic cell proliferation of the Langerhans type, probably resulting from altered immunoregulation. Cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, sc...

journal_title：Journal of the American Academy of Dermatology

authors： Pakula AS,Paller AS

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:No large studies have defined the best treatment of actinic cheilitis. METHODS:We conducted a systematic review to define the best therapies for actinic cheilitis in clinical response and recurrences. RESULTS:We first identified 444 papers, and 49 were finally considered, including 789 patients and 843 tre...

journal_title：Journal of the American Academy of Dermatology

authors： Lai M,Pampena R,Cornacchia L,Pellacani G,Peris K,Longo C

更新日期：2020-09-01 00:00:00

abstract：:The Fourth Annual Symposium on Hidradenitis Suppurativa (SHSA) took place on November 1-3, 2019, at the Westin Book Cadillac Hotel in Detroit, Michigan. This symposium was a joint meeting of the US Hidradenitis Suppurativa Foundation and the Canadian Hidradenitis Suppurativa Foundation. This cross-disciplinary meeting...

journal_title：Journal of the American Academy of Dermatology

authors： Narla S,Price KN,Sachdeva M,Shah M,Shi V,Hamzavi I,Alavi A,Lowes MA

更新日期：2021-01-01 00:00:00

abstract：:Mycobacterium avium complex, a common opportunistic pathogen among patients with AIDS, usually manifests as disseminated disease involving the lung, lymph nodes, and gastrointestinal tract. Primary cutaneous infections with M avium complex are extremely rare, and most cutaneous lesions are caused by dissemination. Cut...

journal_title：Journal of the American Academy of Dermatology

authors： Kayal JD,McCall CO

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Spindle cell melanoma (SCM) including desmoplastic melanoma (DM) is a rare variant of malignant melanoma that may present diagnostic difficulties particularly when staining with S100 is negative, weak, focal, or a combination of these. Conventional melanocytic markers in SCM are usually negative. OBJECTIVE:...

journal_title：Journal of the American Academy of Dermatology

authors： Lazova R,Tantcheva-Poor I,Sigal AC

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Sarcoidosis and granuloma annulare (GA) are cutaneous granulomatous disorders that can be difficult to treat. There is evidence of underlying Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway activation in sarcoidosis, suggesting that JAK inhibition might be effective. OBJEC...

journal_title：Journal of the American Academy of Dermatology

authors： Damsky W,Thakral D,McGeary MK,Leventhal J,Galan A,King B

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Needle puncture and infiltrational anesthesia is generally required for minor cutaneous surgical procedures and may be associated with anxiety, fear, discomfort, and pain. The use of topical anesthetics such as eutectic lidocaine/prilocaine 5% cream may provide an alternative means of delivering anesthesia. ...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Sibbald RG

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Telemedicine technology holds great promise for dermatologic health care delivery. However, the clinical outcomes of digital image consultations (teledermatology) must be compared with traditional clinic-based consultations. OBJECTIVE:Our purpose was to assess and compare the reliability and accuracy of der...

journal_title：Journal of the American Academy of Dermatology

authors： Whited JD,Hall RP,Simel DL,Foy ME,Stechuchak KM,Drugge RJ,Grichnik JM,Myers SA,Horner RD

更新日期：1999-11-01 00:00:00

abstract：:Mutations in the cathepsin C gene have recently been detected in Papillon-Lefèvre syndrome (PLS). Until now, 5 cases with the late-onset variation of this disease have been reported in the literature. The genetic background of this type of PLS is still unknown. We describe a 46-year-old woman with late-onset transgred...

journal_title：Journal of the American Academy of Dermatology

authors： Pilger U,Hennies HC,Truschnegg A,Aberer E

更新日期：2003-11-01 00:00:00