Abstract:
:Chronic herpesvirus infections are common in patients infected with HIV. Atypical skin lesions secondary to long-standing varicella-zoster virus (VZV) infection have been reported. We present a case of an AIDS patient with a chronic VZV infection that simulated a basal cell carcinoma. Histologic examination and immunohistochemistry confirmed the presence of the virus in the follicular epithelium. In the immunocompromised patient, biopsies should be performed on all suspicious lesions because medically-treatable infections may take on the appearance of malignancy.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Tsao H,Tahan SR,Johnson RAdoi
10.1016/s0190-9622(97)70033-1subject
Has Abstractpub_date
1997-05-01 00:00:00pages
831-3issue
5 Pt 2eissn
0190-9622issn
1097-6787pii
S0190-9622(97)70033-1journal_volume
36pub_type
杂志文章abstract:BACKGROUND:Necrobiotic xanthogranuloma (NXG) is a rare histiocytic disorder of unknown origin. OBJECTIVE:We conducted an investigation of skin biopsy specimens from 7 patients with NXG for the presence of Borrelia by focus-floating microscopy. METHODS:Focus-floating microscopy is a recently described, modified immuno...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2007.05.016
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Often after biopsy a skin cancer appears to resolve clinically and a repeat biopsy may be done on the area in question before proceeding with further treatment. OBJECTIVE:Our purpose was to assess the value of a subsequent biopsy in the treatment of skin cancers previously diagnosed by biopsy results. METH...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(92)70159-d
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Nonmelanoma skin cancer (NMSC) incidence in patients with vitiligo has not been studied. OBJECTIVE:We sought to quantify the incidence of NMSC in patients with vitiligo. METHODS:A cohort of 477 patients with vitiligo and no history of NMSC seen in an outpatient academic center between January 2001 and Dece...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2008.09.033
更新日期:2009-06-01 00:00:00
abstract::Angiolymphoid hyperplasia with eosinophilia developed in a 13-year-old boy. The immune phenotype of infiltrating cells and the distribution of adhesion molecules of the integrin, immunoglobulin, and selectin families were analyzed with monoclonal antibodies. The infiltrate consisted mainly of helper lymphocytes, monoc...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(92)70109-s
更新日期:1992-05-01 00:00:00
abstract::A newcomer in the cosmetic market, the tan accelerator, has stimulated much publicity in recent months. We studied the effects of two brands of this product, used according to package instructions, in eighteen healthy volunteers. Readings at 24, 72, 96 hours, and 1 week failed to show augmented tanning. Our study cont...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(87)70099-1
更新日期:1987-04-01 00:00:00
abstract::A 16-year-old male patient had multiple angiokeratotic lesions arranged in a linear pattern on his left arm. Histopathologic examination showed characteristic features of verrucous hemangioma. This entity should be distinguished from angiokeratoma or simple hemangioma. The linear arrangement of lesions as observed in ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(00)90232-9
更新日期:2000-03-01 00:00:00
abstract::Pyoderma gangrenosum (PG) has four distinctive clinical and histologic variants. Some have morphologic and histologic overlapping features with other reactive neutrophilic skin conditions. PG often occurs in association with a systemic disease, and the specific clinical features of the skin lesion may provide a clue t...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(96)90428-4
更新日期:1996-03-01 00:00:00
abstract::The Americans With Disabilities Act (ADA) defines disability as a physical or mental impairment that substantially limits one or more major life activities. Although dermatology has received relatively little attention in the context of disability law, dermatologic diseases are properly covered by the ADA and are subj...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1067/mjd.2002.128384
更新日期:2002-12-01 00:00:00
abstract::The most problematic vulvovaginal conditions are familiar to dermatologists but may exhibit distinct clinical features or medication management because of the anatomic location. The second article in this continuing medical education series focuses on management pearls for treating vulvar diseases. We highlight key co...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2019.10.077
更新日期:2020-06-01 00:00:00
abstract::To evaluate the sensitivity of histologic criteria 396 hematoxylin-eosin-stained step sections of 150 randomly sampled thin malignant melanomas (tumor thickness, less than or equal to 1.5 mm; level of invasion, I-III) were analyzed. The highest sensitivity was determined for nuclear atypia (84%), followed by the asymm...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(89)70143-2
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND:Hereditary palmoplantar keratoderma (HPPK), type papulosa, is rare, and epidemiologic data are sporadic and inconsistent. An epidemiologic population study of this disease has not been performed previously. OBJECTIVE:We performed a large population study on prevalence of HPPK, type papulosa, in Croatia. ME...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(93)70207-a
更新日期:1993-09-01 00:00:00
abstract::We report the coexistence of pemphigus vulgaris and Paget's disease of the nipple in a patient with a documented history of pemphigus and a 2-year complaint of an eczematous breast lesion. A biopsy taken from the lesion showed the characteristic histologic features of both pemphigus and Paget's disease of the nipple. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(87)80071-3
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Psoralen plus ultraviolet A (PUVA) for the treatment of psoriasis has never been evaluated using the Psoriasis Area Severity Index (PASI) in a randomized, double-blind, placebo-controlled trial. The lack of such data limits our capacity to estimate PUVA's efficacy relative to other treatment options that are...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaad.2009.04.053
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Noninvasive fat removal is preferred because of decreased downtime and lower perceived risk. It is important to seek new noninvasive fat removal treatments that are both safe and efficacious. OBJECTIVE:To assess the extent to which carboxytherapy, which is the insufflation of carbon dioxide gas into subcuta...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaad.2018.04.038
更新日期:2018-08-01 00:00:00
abstract::"Poikiloderma" is a morphologic and descriptive term referring to a combination of cutaneous atrophy, telangiectasia, and varied macular pigmentary changes that result in a mottled skin appearance. Its etiology includes both congenital and acquired causes. Many studies have reported different causes of acquired poikil...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2012.06.015
更新日期:2013-09-01 00:00:00
abstract::The efficacy of a sunscreen containing an investigational drug, butyl methoxydibenzoylmethane in combination with padimate O against the erythemogenic effect of ultraviolet A (UVA) radiation was evaluated in two double-blind studies involving subjects sensitized with topical 8-methoxypsoralen. UVA radiation was suppli...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章
doi:10.1016/s0190-9622(87)70195-9
更新日期:1987-08-01 00:00:00
abstract::Dermatomyositis (DM) is an idiopathic inflammatory myopathy. The mainstay of treatment for DM is oral corticosteroids. However, the dose and length of treatment is debated. Adding to the confusion, there have been no randomized controlled studies comparing the use of various corticosteroid doses and taper rates, and n...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2008.02.043
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:The plasma concentration of bleomycin after injection of bleomycin into warts is unknown, as is the long-term stability of bleomycin solution. OBJECTIVE:Our purpose was to measure plasma bleomycin concentration after injection of bleomycin into warts, to relate histologic and immunocytochemical changes in w...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(93)70133-e
更新日期:1993-06-01 00:00:00
abstract::We performed a 22-month trial of topical tretinoin (retinoic acid) in the treatment of photoaging. Thirty patients participated in a 4-month, randomized, blinded, vehicle-controlled study that has been reported previously; 21 patients continued tretinoin therapy on an open-label basis, participating in the study for a...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0190-9622(90)70265-j
更新日期:1990-10-01 00:00:00
abstract::In addition to being recognized as a chronic inflammatory disease that manifests in the skin, psoriasis is increasingly understood to be a systemic disease that causes immune dysregulation throughout the body. The systemic nature of psoriasis is evidenced by the higher burden of comorbidities and shorter life expectan...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2018.02.040
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Hereditary polymorphic light eruption (HPLE) occurs unique ly in the American Indian and Inuit and exhibits autosomal dominant transmission. Because the cutaneous expression of HPLE resembles that of polymorphic light eruption (PLE) and because many non-Indians in the United States have American Indian herit...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(96)80060-0
更新日期:1996-04-01 00:00:00
abstract::A set of three comparison studies under varying conditions was performed to determine the efficacy of a cotton swab technic for obtaining material for culture of dermatophyte infections. Matched fungal cultures, one by swab and one by scrape, on each of 110 subjects showed that there was no difference in the two metho...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(84)80455-7
更新日期:1984-11-01 00:00:00
abstract::The use of the various forms of phototherapy remains an essential treatment option for psoriasis vulgaris. Expertise concerning the mechanisms involved with the actions of therapeutic ultraviolet light and the proper delivery of office-based treatments resides within the specialty of dermatology. New therapies for the...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(03)01139-3
更新日期:2003-08-01 00:00:00
abstract::We present the identification and characterization of two patients with xeroderma pigmentosum (XP) and squamous cell carcinoma of the tongue. Dermal fibroblasts from two black siblings with XP were shown to be hypersensitive to ultraviolet (UV) light measured by colony-forming ability. UV-induced unscheduled deoxyribo...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(85)70072-2
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND:Pulsed dye laser treatment and other cosmetic procedures result in significant bruising. Claims have been made regarding the efficacy of topical vitamin K in both preventing and speeding the clearing of bruising; however, well-controlled studies are lacking. OBJECTIVE:The purpose of this study is to evaluat...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1067/mjd.2002.120465
更新日期:2002-08-01 00:00:00
abstract::Allergic contact dermatitis has been considered the most common of the many dermatologic conditions found with eyelid dermatitis. This is a retrospective study of 203 patients who presented with persistent or recurrent eyelid dermatitis with or without dermatitis elsewhere. Almost all underwent patch testing and, when...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2002.122736
更新日期:2002-11-01 00:00:00
abstract::A patient who had pemphigus vulgaris received therapy with gold thiomalate in addition to dexamethasone. Three weeks after the initiation of parenteral gold the patient developed acute hepatitis. Causes other than gold toxicity were ruled out, and the patient recovered completely after discontinuation of gold therapy....
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(93)70019-p
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Despite a lack of evidence that dysplastic nevi are precursors to melanoma, a large proportion of dermatologists continue to treat them as such. Emerging data suggest that histologic grading approach may result in many unnecessary excisions. OBJECTIVE:Using a nongrading approach to diagnosis of Clark/dyspla...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2015.09.030
更新日期:2016-01-01 00:00:00
abstract::A 56-year-old man had a deeply invasive leiomyosarcoma of the right buttock. Leiomyosarcomas of the skin and subcutaneous tissues are rare, and most occur on the extremities. Wide local excision is the therapy of choice. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(91)70094-i
更新日期:1991-04-01 00:00:00
abstract::We describe a case of generalized, asymptomatic, chronic annular lichen planus. The centers of the large annular lesions were atrophic and had lost their elasticity. Histologic examination revealed an absence of elastic fiber in the center. Electron microscopy revealed fragmented elastic fibers. Examination of early l...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(91)70212-k
更新日期:1991-08-01 00:00:00