Coexistent pemphigus vulgaris and Paget's disease of the nipple. An immunohistochemical study.

abstract：:Skin cancer is less prevalent in people of color than in the white population. However, when skin cancer occurs in non-whites, it often presents at a more advanced stage, and thus the prognosis is worse compared with white patients. The increased morbidity and mortality associated with skin cancer in patients of color...

journal_title：Journal of the American Academy of Dermatology

authors： Agbai ON,Buster K,Sanchez M,Hernandez C,Kundu RV,Chiu M,Roberts WE,Draelos ZD,Bhushan R,Taylor SC,Lim HW

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:A scattered generalized distribution (SGD) of dermatitis is a challenging problem; patch testing is a strategy for evaluating allergic contact dermatitis as a relevant factor. OBJECTIVE:We sought to analyze patient characteristics and most frequently relevant positive allergens in patients presenting for pa...

journal_title：Journal of the American Academy of Dermatology

authors： Zug KA,Rietschel RL,Warshaw EM,Belsito DV,Taylor JS,Maibach HI,Mathias CG,Fowler JF Jr,Marks JG Jr,DeLeo VA,Pratt MD,Sasseville D,Storrs FJ

更新日期：2008-09-01 00:00:00

abstract：:In pyodermatitis-pyostomatitis vegetans annular pustular cutaneous lesions may precede, accompany, or follow the usually extensive vegetating oral disease. Sometimes only cutaneous or only oral lesions occur and previously have been described as separate entities. Clinical, histopathologic, and immunopathologic eviden...

journal_title：Journal of the American Academy of Dermatology

authors： Storwick GS,Prihoda MB,Fulton RJ,Wood WS

更新日期：1994-08-01 00:00:00

abstract：:Splinter hemorrhages are non-blanchable usually distal reddish-brown linear hemorrhages beneath the nails. Among a variety of etiologic factors reported, trauma is the most common cause. A 26-year-old Hispanic female presented with asymptomatic, extensive fingernail hemorrhages of two months duration. There was no his...

journal_title：Journal of the American Academy of Dermatology

authors： Saladi RN,Persaud AN,Rudikoff D,Cohen SR

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:The incidence of melanoma is rising faster than that of any other preventable cancer in the United States. The American Academy of Dermatology has sponsored free skin cancer education and screenings conducted by volunteer dermatologists in the United States since 1985. OBJECTIVE:We aimed to assess the Ameri...

journal_title：Journal of the American Academy of Dermatology

authors： Okhovat JP,Beaulieu D,Tsao H,Halpern AC,Michaud DS,Shaykevich S,Geller AC

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:The adult burden of atopic dermatitis (AD) is poorly characterized. OBJECTIVE:We sought to characterize AD burden in adults with moderate to severe disease from the patient's perspective. METHODS:Patient-reported outcomes collected at screening in a phase 2b clinical trial of dupilumab included pruritus nu...

journal_title：Journal of the American Academy of Dermatology

authors： Simpson EL,Bieber T,Eckert L,Wu R,Ardeleanu M,Graham NM,Pirozzi G,Mastey V

更新日期：2016-03-01 00:00:00

abstract：:Sixty patients were treated for tinea pedis with 2% topical ketoconazole cream either once or twice daily. All diagnoses were confirmed mycologically. They were randomly assigned in a double-blind study into three groups on the basis of their clinical lesions, that is, vesicular pedis, interdigital pedis, and hyperker...

journal_title：Journal of the American Academy of Dermatology

authors： Greer DL

更新日期：1987-03-01 00:00:00

abstract：:Botryomycosis in an uncommon chronic bacterial infection that mimics fungal disease clinically and histologically. Microscopically the hallmark of the disease is the presence of fungus-like granules in which the causative organism is embedded. A patient with typical cutaneous botryomycosis is presented, along with the...

journal_title：Journal of the American Academy of Dermatology

authors： Brunken RC,Lichon-Chao N,van der Broek H

更新日期：1983-09-01 00:00:00

abstract：:We describe a patient with hypereosinophilic syndrome, who had severe cutaneous eruptions. Immunohistochemical study revealed that dermal endothelial cells in the lesional skin of this patient expressed eotaxin, which indicates eotaxin plays a part in inducing eosinophil migration into cutaneous tissue in hypereosinop...

journal_title：Journal of the American Academy of Dermatology

authors： Tsunemi Y,Idezuki T,Nakamura K,Tamaki K

更新日期：2003-11-01 00:00:00

abstract：:Talimogene laherparepvec (T-VEC) is an oncolytic virus based on herpes simplex virus type 1 approved for intralesional treatment of advanced melanoma. In this article, we review the clinical literature on T-VEC for advanced melanoma and provide a practical approach to using T-VEC in the dermatologic surgery and oncolo...

journal_title：Journal of the American Academy of Dermatology

authors： Haitz K,Khosravi H,Lin JY,Menge T,Nambudiri VE

更新日期：2020-07-01 00:00:00

abstract：:Three siblings with infantile-onset biotin-responsive multiple carboxylase deficiency are described. Recognition of the characteristic dermatologic manifestations, alopecia and periorificial dermatitis, should result in early diagnosis and institution of potentially lifesaving therapy with biotin. Other metabolic diso...

journal_title：Journal of the American Academy of Dermatology

authors： Williams ML,Packman S,Cowan MJ

更新日期：1983-07-01 00:00:00

abstract：:The great diversity of wounds and the broad range of available dressings complicate the selection of proper chronic wound treatment. Choosing the right treatment is the essential step in the healing process. In this review, we focus on chronic nonhealing ulcers, which are a critical problem in clinical practice, and c...

journal_title：Journal of the American Academy of Dermatology

authors： Skórkowska-Telichowska K,Czemplik M,Kulma A,Szopa J

更新日期：2013-04-01 00:00:00

abstract：:Conventional chemotherapy continues to be an important part of cancer management, but may cause various cutaneous reactions because it disturbs specific cell cycle phases. The alkylating agents cyclophosphamide, ifosfamide, and thiotepa can produce hyperpigmentation, while hypersensitivity reactions can be seen with p...

journal_title：Journal of the American Academy of Dermatology

authors： Reyes-Habito CM,Roh EK

更新日期：2014-08-01 00:00:00

abstract：:Dermatomyositis (DM) is an idiopathic inflammatory myopathy. The mainstay of treatment for DM is oral corticosteroids. However, the dose and length of treatment is debated. Adding to the confusion, there have been no randomized controlled studies comparing the use of various corticosteroid doses and taper rates, and n...

journal_title：Journal of the American Academy of Dermatology

authors： Iorizzo LJ 3rd,Jorizzo JL

更新日期：2008-07-01 00:00:00

abstract：:Allergic contact dermatitis (ACD), a delayed hypersensitivity skin reaction to environmental allergens, has a prevalence that is similar in children and adults. However, diagnostic testing for ACD in pediatric populations accounts for less than one tenth of all patch tests. The relative infrequency of pediatric patch ...

journal_title：Journal of the American Academy of Dermatology

authors： Neale H,Garza-Mayers AC,Tam I,Yu J

更新日期：2021-02-01 00:00:00

abstract：:The psychosocial impact of infection with human immunodeficiency virus (HIV) can be viewed from three perspectives: (1) the issues focused by acquired immunodeficiency syndrome (AIDS), (2) the persons affected, and (3) the emotions encountered. Among the many issues faced by AIDS patients, their families, and their ca...

journal_title：Journal of the American Academy of Dermatology

authors： Cline DJ

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Electronic claims and medical record databases are increasingly used for observational studies of psoriasis. The purpose of this study was to assess the validity of psoriasis diagnostic codes in an electronic database. METHODS:This study was performed in a population-based setting in Olmsted County, Minneso...

journal_title：Journal of the American Academy of Dermatology

authors： Icen M,Crowson CS,McEvoy MT,Gabriel SE,Maradit Kremers H

更新日期：2008-12-01 00:00:00

abstract：:In two double-blind, parallel-group, multicenter trials, 0.05% halobetasol propionate cream was compared with 0.05% clobetasol 17-propionate cream and 0.05% betamethasone dipropionate cream in 264 patients with acute, severe exacerbations of atopic dermatitis. The efficacy of halobetasol propionate cream and betametha...

journal_title：Journal of the American Academy of Dermatology

authors： Yawalkar SJ,Schwerzmann L

更新日期：1991-12-01 00:00:00

abstract：:Alendronate is a bisphosphonate compound used to treat diseases of pathologic bone resorption. Cutaneous reactions to this medication are rare. We report the case of a superficial gyrate erythema that occurred as a reaction to weekly alendronate therapy used in the treatment of postmenopausal osteoporosis. ...

journal_title：Journal of the American Academy of Dermatology

authors： High WA,Cohen JB,Wetherington W,Cockerell CJ

更新日期：2003-06-01 00:00:00

abstract：:The presence of mast cells, often in an activated state or increased numbers, has been noted in various cutaneous disorders. Recent studies suggest that mast cells are of primary importance in these conditions and their presence does not merely represent a secondary event. This review focuses on atopic dermatitis, con...

journal_title：Journal of the American Academy of Dermatology

authors： Rothe MJ,Nowak M,Kerdel FA

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Brachioradial pruritus (BRP) is a localized pruritus of the dorsolateral aspect of the arm. BRP is an enigmatic condition with a controversial cause; some authors consider BRP to be a photodermatosis whereas other authors attribute BRP to compression of cervical nerve roots. OBJECTIVE:We sought to investiga...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen AD,Masalha R,Medvedovsky E,Vardy DA

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Genital or vulval lichen planus (VLP) may have a disabling effect on a patient's quality of life. Evidence-based management guidelines are lacking for VLP. OBJECTIVE:We sought to review clinical presentation and treatment of patients who received a diagnosis of VLP. METHODS:The 100 consecutive patients who...

journal_title：Journal of the American Academy of Dermatology

authors： Fahy CMR,Torgerson RR,Davis MDP

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Hidradenitis suppurativa (HS) is a chronic inflammatory disease involving intertriginous skin. Previous epidemiologic studies have been limited by small sample size. OBJECTIVE:We sought to describe the prevalence and comorbidities of HS in a large patient care database. METHODS:In this retrospective case-c...

journal_title：Journal of the American Academy of Dermatology

authors： Shlyankevich J,Chen AJ,Kim GE,Kimball AB

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Acne is a multifactorial disease in which androgens appear to play an important role. A low-dose oral contraceptive containing 20 microg of ethinyl estradiol and 100 microg of levonorgestrel (EE/LNG) has been shown to improve biochemical markers of androgenicity. Lowering bioavailable androgens may improve a...

journal_title：Journal of the American Academy of Dermatology

authors： Leyden J,Shalita A,Hordinsky M,Swinyer L,Stanczyk FZ,Weber ME

更新日期：2002-09-01 00:00:00

abstract：:Angioedema is characterized by localized swelling of sudden onset affecting the skin and/or mucous membranes. It can be classified into hereditary and acquired forms. Hereditary angioedema is a rare disease inherited as an autosomal dominant trait and caused by a deficiency of C1-esterase inhibitor. Acute attacks are ...

journal_title：Journal of the American Academy of Dermatology

authors： Greaves M,Lawlor F

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Giant angiofibromas in patients with tuberous sclerosis complex (TSC) are rare. OBJECTIVE:We sought to report two patients who had TSC with unusually large and disfiguring facial angiofibromas and to identify underlying histopathologic changes that may possibly explain the clinical features. METHODS:We per...

journal_title：Journal of the American Academy of Dermatology

authors： Kacerovska D,Kerl K,Michal M,Filipova H,Vrtel R,Vanecek T,Zelenakova H,Kraus J,Kodet R,Kazakov DV

更新日期：2012-12-01 00:00:00

abstract：:Infantile leukemia accounts for only 3% of childhood leukemia. Leukemia cutis occurs in 25% to 30% of infants with congenital leukemia and is more frequently associated with acute myeloid leukemia than with acute lymphoblastic leukemia. We describe an infant in whom hyperpigmented macules that developed when the patie...

journal_title：Journal of the American Academy of Dermatology

authors： Yen A,Sanchez R,Oblender M,Raimer S

更新日期：1996-02-01 00:00:00

abstract：:As the most common human cancer worldwide and continuing to increase in incidence, basal cell carcinoma is associated with significant morbidity and cost. Continued advances in research have refined both our insight and approach to this seemingly ubiquitous disease. This 2-part continuing medical education article wil...

journal_title：Journal of the American Academy of Dermatology

authors： Cameron MC,Lee E,Hibler BP,Barker CA,Mori S,Cordova M,Nehal KS,Rossi AM

更新日期：2019-02-01 00:00:00

abstract：:We describe a female patient with an acute purpuric and bullous eruption mainly affecting the lower aspect of the legs. Skin biopsy specimens demonstrated microvascular occlusions with fibrin thrombi but no dermal inflammation. Intermediate hyperhomocysteinemia and transient antiphospholipid antibodies were evidenced ...

journal_title：Journal of the American Academy of Dermatology

authors： Martin L,Armingaud P,Georgescu V,Matre F,Legac E,Estève E

更新日期：2003-08-01 00:00:00

abstract：:Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In this first of 5 sections of the guidelines of care for psoriasis, we discuss the classification of psoriasis; associated comorbidities including autoimmune...

journal_title：Journal of the American Academy of Dermatology

authors： Menter A,Gottlieb A,Feldman SR,Van Voorhees AS,Leonardi CL,Gordon KB,Lebwohl M,Koo JY,Elmets CA,Korman NJ,Beutner KR,Bhushan R

更新日期：2008-05-01 00:00:00