The local treatment and available dressings designed for chronic wounds.

abstract：:Nevoid hyperkeratosis of the nipple and areola, which is characterized by verrucous thickening and pigmentation of the nipple or areola, is a rare condition. Different therapeutic options have been used with varying results, but there is no uniformly effective treatment. We describe two patients with hyperkeratosis of...

journal_title：Journal of the American Academy of Dermatology

authors： Bayramgürler D,Bilen N,Apaydin R,Erçin C

更新日期：2002-01-01 00:00:00

abstract：:A 38-year-old woman came for treatment of multiple clear vesicles and hemorrhagic papules on the posterior aspect of the right shoulder and the right axillary vault of 5 years' duration. These lesions would spontaneously manifest as clear or blood-filled vesicles (or both) and appear to be exacerbated by physical cont...

journal_title：Journal of the American Academy of Dermatology

authors： Bikowski JB,Dumont AM

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Finasteride, a type II 5alpha-reductase inhibitor, reduces scalp and serum dihydrotestosterone and has been shown to be effective in men with androgenetic alopecia (AGA). OBJECTIVE:The purpose of this study was to determine the effect of finasteride on scalp hair weight in men with AGA. METHODS:Sixty-six m...

journal_title：Journal of the American Academy of Dermatology

authors： Price VH,Menefee E,Sanchez M,Ruane P,Kaufman KD

更新日期：2002-04-01 00:00:00

abstract：:This report describes a 25-year-old white woman with lentigines, cutaneous myxomas, bilateral atrial myxomas, and cerebral artery aneurysms. We believe this case to be the fifth reported case of this unusual association in the medical literature, with the additional finding of a central nervous system aneurysm. In the...

journal_title：Journal of the American Academy of Dermatology

authors： Reed OM,Mellette JR Jr,Fitzpatrick JE

更新日期：1986-08-01 00:00:00

abstract：:Conventional chemotherapy continues to be an important part of cancer management, but may cause various cutaneous reactions because it disturbs specific cell cycle phases. The alkylating agents cyclophosphamide, ifosfamide, and thiotepa can produce hyperpigmentation, while hypersensitivity reactions can be seen with p...

journal_title：Journal of the American Academy of Dermatology

authors： Reyes-Habito CM,Roh EK

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Severe atopic dermatitis (AD) is increasingly treated with systemic immuno-modulatory drugs yet their safety is unclear. OBJECTIVE:We evaluated the comparative risk of serious bacterial and opportunistic infections among users of systemic immuno-modulatory medications in patients with severe AD in routine c...

journal_title：Journal of the American Academy of Dermatology

authors： Schneeweiss MC,Perez-Chada L,Merola JF

更新日期：2019-05-31 00:00:00

abstract：:Glyceryl monothioglycolate has recently been implicated as an allergen. A case of a hairdresser who used this material is presented. He appeared to have an irritant contact dermatitis on his fingertips. Patch testing the patient and extensive patch testing in a group of fifty-four volunteers showed a very high inciden...

journal_title：Journal of the American Academy of Dermatology

authors： Rapaport M

更新日期：1983-11-01 00:00:00

abstract：:Primary hyperoxaluria encompasses 3 rare genetic disorders of glyoxylate metabolism characterized by excessive urinary excretion of oxalic acid, resulting in oxalosis. Patients typically have recurrent calcium oxalate nephrolithiasis and nephrocalcinosis, leading to chronic renal failure and death from uremia. Oxalate...

journal_title：Journal of the American Academy of Dermatology

authors： Marconi V,Mofid MZ,McCall C,Eckman I,Nousari HC

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Lack of agreement on how to accurately capture disease outcomes in localized scleroderma (LS) has hindered the development of efficacious treatment protocols. The LS Cutaneous Assessment Tool (LoSCAT), consisting of the modified LS Skin Severity Index (mLoSSI) and the LS Damage Index, has potential for use i...

journal_title：Journal of the American Academy of Dermatology

authors： Kelsey CE,Torok KS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Little is known about how individuals with a predisposition for rosacea appear in childhood. This retrospective, matched control, longitudinal study examined the relationship between childhood stye and adult rosacea. METHODS:The records of the Rochester Epidemiology Project were examined to identify patient...

journal_title：Journal of the American Academy of Dermatology

authors： Bamford JT,Gessert CE,Renier CM,Jackson MM,Laabs SB,Dahl MV,Rogers RS 3rd

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Recent studies have shown a higher prevalence of cardiovascular (CV) risk factors in patients with rosacea. However, it remains unknown whether rosacea represents an independent CV risk factor. OBJECTIVE:We evaluated the risk of myocardial infarction, stroke, CV death, major adverse CV events, and all-cause...

journal_title：Journal of the American Academy of Dermatology

authors： Egeberg A,Hansen PR,Gislason GH,Thyssen JP

更新日期：2016-08-01 00:00:00

abstract：UNLABELLED:Sentinel lymph node biopsy for melanoma was introduced in the early 1990s as a minimally invasive method of identifying and pathologically staging regional lymph node basins in patients with clinical stage I/II melanoma. Numerous large trials have demonstrated that sentinel lymph node evaluation has utility ...

journal_title：Journal of the American Academy of Dermatology

authors： Stebbins WG,Garibyan L,Sober AJ

更新日期：2010-05-01 00:00:00

abstract：:We report eight patients with ulcerative colitis who have subsequently developed pemphigoid. Four patients were investigated to determine the pattern of pemphigoid antibody staining on whole and chemically split skin and oral mucosa to distinguish between pemphigoid and epidermolysis bullosa acquisita. The findings we...

journal_title：Journal of the American Academy of Dermatology

authors： Barth JH,Kelly SE,Wojnarowska F,Savin JA,Whittaker S,Cream JJ,White JE

更新日期：1988-08-01 00:00:00

abstract：:At the International Consensus Conference for Cutaneous T-Cell Lymphoma (CTCL) Treatment Recommendations (held in Boston, Massachusetts, Oct. 1 and 2, 1994), international experts were asked to assess where consensus existed and to identify areas that required clinical research. We review the epidemiology, pathology, ...

journal_title：Journal of the American Academy of Dermatology

authors： Demierre MF,Foss FM,Koh HK

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:In 1982 we reported our preliminary observations on the use of home UV phototherapy for patch and early plaque phase mycosis fungoides (MF). OBJECTIVE:Our purpose was to present follow-up data of the original 31 patients, covering an interval of up to 15 years. METHODS:All patients used a commercially avai...

journal_title：Journal of the American Academy of Dermatology

authors： Resnik KS,Vonderheid EC

更新日期：1993-07-01 00:00:00

abstract：:Hutchinson's sign, periungual extension of brown-black pigmentation from longitudinal melanonychia onto the proximal and lateral nailfolds, is an important indicator of subungual melanoma. However, experience has demonstrated that Hutchinson's sign, although valuable, is not an infallible predictor of melanoma. Periun...

journal_title：Journal of the American Academy of Dermatology

authors： Baran R,Kechijian P

更新日期：1996-01-01 00:00:00

abstract：:Five patients with cutaneous leishmaniasis are described. Four of these patients acquired leishmaniasis in Texas. Four cases represent acute cutaneous leishmaniasis, and one case probably represents chronic cutaneous leishmaniasis. The classification and treatment of cutaneous leishmaniasis are reviewed. One patient i...

journal_title：Journal of the American Academy of Dermatology

authors： Nelson DA,Gustafson TL,Spielvogel RL

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:Differentiation between seborrheic keratosis (SK) and skin cancers may be difficult. Reflectance confocal microscopy (RCM) enables noninvasive assessment of skin neoplasms at cellular-level resolution. OBJECTIVE:We sought to describe RCM features of SK and to correlate these RCM findings with dermoscopic st...

journal_title：Journal of the American Academy of Dermatology

authors： Ahlgrimm-Siess V,Cao T,Oliviero M,Laimer M,Hofmann-Wellenhof R,Rabinovitz HS,Scope A

更新日期：2013-07-01 00:00:00

abstract：:The 3 major features of psoriasis--abnormal differentiation of keratinocytes, hyperproliferation of keratinocytes, and infiltration of inflammatory components into the skin--can be quantified by measuring levels of certain biochemical markers. Psoriasis is associated with upregulation or downregulation of several of t...

journal_title：Journal of the American Academy of Dermatology

authors： Duvic M,Asano AT,Hager C,Mays S

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Confirmation of mild bites caused by Loxosceles reclusa with swab testing has not been previously documented, to our knowledge. METHODS:We report a case using an enzyme-linked immunosorbent assay (ELISA) test. RESULTS:A lesion lacking necrosis or other specific signs of loxoscelism was confirmed by identif...

journal_title：Journal of the American Academy of Dermatology

authors： Stoecker WV,Green JA,Gomez HF

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Seborrheic dermatitis is commonly treated with anti-inflammatory products, including topical corticosteroids. Pimecrolimus cream 1% also exerts anti-inflammatory activity by inhibiting T-cell cytokine production. OBJECTIVE:We sought to compare the efficacy and safety of twice-daily pimecrolimus for treatmen...

journal_title：Journal of the American Academy of Dermatology

authors： Warshaw EM,Wohlhuter RJ,Liu A,Zeller SA,Wenner RA,Bowers S,Schultz JC,Katz HI,McCormick CL,Parneix-Spake A

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Onychomycosis is a common nail infection, often resulting in nail plate damage and deformity. Topical lacquer treatments have negligible efficacy. Oral treatments, although more efficacious, are limited by drug interactions and potential hepatotoxicity. OBJECTIVE:We investigated the safety and efficacy of e...

journal_title：Journal of the American Academy of Dermatology

authors： Elewski BE,Rich P,Pollak R,Pariser DM,Watanabe S,Senda H,Ieda C,Smith K,Pillai R,Ramakrishna T,Olin JT

更新日期：2013-04-01 00:00:00

abstract：:We studied the effects of two retinoids, naturally occurring all-trans-retinoic acid (retinoic acid) and the synthetic 4-hydroxyphenylretinamide (4-OH-PRT) on monolayer cultures of rabbit synovial fibroblasts and on explants of rabbit articular cartilage. Treatment of fibroblasts with phorbol myristate acetate (PMA; 1...

journal_title：Journal of the American Academy of Dermatology

authors： Brinckerhoff CE,Nagase H,Nagel JE,Harris ED Jr

更新日期：1982-04-01 00:00:00

abstract：:The case of a male diabetic patient with recurrent bullous lesions restricted to the hands is reported. Areas of spongiosis in the epidermis, as well as subepidermal blister formation, were observed in repeated biopsies. On electron microscopy, separation was seen at the level of the lamina lucida. No immunopathology ...

journal_title：Journal of the American Academy of Dermatology

authors： Toonstra J

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Epidemiology and patterns of antibiotic resistance for Staphylococcus aureus are changing in the United States. OBJECTIVE:We sought to determine the epidemiology and antibiotic susceptibility profiles in S aureus cutaneous infections in a pediatric dermatology tertiary health care facility in North Carolina...

journal_title：Journal of the American Academy of Dermatology

authors： Ortega-Loayza AG,Diamantis SA,Gilligan P,Morrell DS

更新日期：2010-05-01 00:00:00

abstract：UNLABELLED:Cutaneous vascular malformations are rare disorders representing errors in vascular development. These lesions occur much less commonly but are often confused with the common infantile hemangioma. It is important to properly diagnose vascular malformations because of their distinct differences in morbidity, ...

journal_title：Journal of the American Academy of Dermatology

authors： Garzon MC,Huang JT,Enjolras O,Frieden IJ

更新日期：2007-04-01 00:00:00

abstract：:We describe a patient with vitamin A deficiency phrynoderma caused by a combination of inadequate dietary intake of vitamin A and beta-carotene and malabsorption secondary to primary visceral myopathy and total colectomy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bleasel NR,Stapleton KM,Lee MS,Sullivan J

更新日期：1999-08-01 00:00:00

abstract：:A young woman developed minocycline-related lupus erythematosus with associated autoimmune hepatitis. All clinical and laboratory abnormalities returned to normal when the drug was stopped. The symptoms worsened dramatically upon rechallenge, strongly suggesting the reaction was related to the minocycline. ...

journal_title：Journal of the American Academy of Dermatology

authors： Crosson J,Stillman MT

更新日期：1997-05-01 00:00:00

abstract：:Diagnosis and classification of cutaneous lymphoid infiltrates are often hampered by lack of frozen tissue to allow detailed immunophenotyping. Therefore antibodies that recognize antigens resistant to routine tissue processing would be of value. In this study we present a detailed analysis of two such antibodies agai...

journal_title：Journal of the American Academy of Dermatology

authors： Sterry W,Hauschild A

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Maternal smoking during pregnancy has been shown to lead to immunologic changes in the offspring. However, little is known about the influence of this exposure on atopic manifestations. OBJECTIVE:Our purpose was to investigate the influence of air pollutants on manifestations of atopy in preschool children....

journal_title：Journal of the American Academy of Dermatology

authors： Schäfer T,Dirschedl P,Kunz B,Ring J,Uberla K

更新日期：1997-04-01 00:00:00