Abstract:
BACKGROUND:A scattered generalized distribution (SGD) of dermatitis is a challenging problem; patch testing is a strategy for evaluating allergic contact dermatitis as a relevant factor. OBJECTIVE:We sought to analyze patient characteristics and most frequently relevant positive allergens in patients presenting for patch testing with SGD. METHODS:We conducted retrospective cross-sectional analysis of North American Contact Dermatitis Group 2001 to 2004 data. Patients with SGD were compared with patients without SGD. RESULTS:Of 10,061 patients, 14.9% (n = 1497) had only a SGD. Men and patients with a history of atopic eczema were more likely to have dermatitis in a SGD (P < .001). Preservatives, fragrances, propylene glycol, cocamidopropyl betaine, ethyleneurea melamine formaldehyde, tixocortol pivalate, and budesonide were among the more frequently relevant positive allergens. Top allergen sources included cosmetics/beauty preparations/skin and health care products, clothing, and topical corticoids. LIMITATIONS:This was a retrospective analysis of patch-tested patients with SGD suspected to have allergy. CONCLUSIONS:A total of 49% of patients with SGD had at least one relevant positive allergen, thus demonstrating the benefit of patch testing these patients.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Zug KA,Rietschel RL,Warshaw EM,Belsito DV,Taylor JS,Maibach HI,Mathias CG,Fowler JF Jr,Marks JG Jr,DeLeo VA,Pratt MD,Sasseville D,Storrs FJdoi
10.1016/j.jaad.2008.05.008subject
Has Abstractpub_date
2008-09-01 00:00:00pages
426-31issue
3eissn
0190-9622issn
1097-6787pii
S0190-9622(08)00590-2journal_volume
59pub_type
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