Anticentromere antibody in localized scleroderma.

abstract：:A newcomer in the cosmetic market, the tan accelerator, has stimulated much publicity in recent months. We studied the effects of two brands of this product, used according to package instructions, in eighteen healthy volunteers. Readings at 24, 72, 96 hours, and 1 week failed to show augmented tanning. Our study cont...

journal_title：Journal of the American Academy of Dermatology

authors： Jaworsky C,Ratz JL,Dijkstra JW

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:The decision to perform Mohs micrographic surgery (MMS) or wide local excision (WLE) for eyelid sebaceous carcinoma (SC) is controversial. OBJECTIVE:To compare local recurrence, metastasis, and tumor-related mortality of patients with eyelid SC who were initially treated with MMS versus with WLE. METHODS:A...

journal_title：Journal of the American Academy of Dermatology

authors： Zhou C,Wu F,Chai P,Shi Y,Ye J,Shi X,Tan J,Ding Y,Luo Y,Esmaeli B,Jia R,Fan X

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Safety profiles of systemic biologic agents for the treatment of psoriasis and psoriatic arthritis (PsA) encompass a wide spectrum of adverse events. To date, no uniform evidence-based guidelines exist regarding screening and monitoring patients who are undergoing biologic therapy. OBJECTIVE:We sought to id...

journal_title：Journal of the American Academy of Dermatology

authors： Ahn CS,Dothard EH,Garner ML,Feldman SR,Huang WW

更新日期：2015-09-01 00:00:00

abstract：:Dermatologists frequently are consulted by a pregnant patient or a woman of childbearing age who desires acne therapy. Because there are no published studies in which women took acne medications throughout pregnancy, information about safety must be obtained indirectly from studies in which the agents were taken for a...

journal_title：Journal of the American Academy of Dermatology

authors： Rothman KF,Pochi PE

更新日期：1988-09-01 00:00:00

abstract：UNLABELLED:Skin cancer is the most common cancer in human beings. The increased incidence of skin cancer has brought much attention to the process by which these tumors develop and how they can be prevented. Efforts have been made to educate the public about the importance of protecting skin from excessive ultraviolet ...

journal_title：Journal of the American Academy of Dermatology

authors： Wright TI,Spencer JM,Flowers FP

更新日期：2006-06-01 00:00:00

abstract：:Certain scalp hair shafts from 2 of 10 cases of pili annulati examined by scanning electron microscopy exhibited an unusual weathering pattern. The majority of affected hair shafts showed minor surface abnormalities at regular intervals (nodes) associated with the underlying spaces. However, in a few examples, there w...

journal_title：Journal of the American Academy of Dermatology

authors： Feldmann KA,Dawber RP,Pittelkow MR,Ferguson DJ

更新日期：2001-10-01 00:00:00

abstract：:The etiology of mycosis fungoides (MF) is uncertain, although infectious agents and other environmental exposures have been implicated. We describe what appears to be the first case in which both a husband and his wife were diagnosed with large-cell transformation of MF. After 10 years of having stage I MF, the wife d...

journal_title：Journal of the American Academy of Dermatology

authors： Schmidt AN,Robbins JB,Greer JP,Zic JA

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Enfuvirtide is the first of a new class of antiretroviral agents for the treatment of HIV-1 infection, called the fusion inhibitors. The most common type of adverse event associated with enfuvirtide treatment is injection site reactions, occurring in up to 98% of patients. Many of these lesions are symptomat...

journal_title：Journal of the American Academy of Dermatology

authors： Ball RA,Kinchelow T,ISR Substudy Group.

更新日期：2003-11-01 00:00:00

abstract：:Two cases of semicircular lipoatrophy and one of annular lipoatrophy are presented. The reasons why semicircular lipoatrophy, annular lipoatrophy, and annular atrophy of the ankles seem to be different clinical entities are discussed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rongioletti F,Rebora A

更新日期：1989-03-01 00:00:00

abstract：:We report a detailed clinical, histopathologic, and photobiologic study of 16 Dutch patients with actinic reticuloid. All were middle-aged or elderly men who had persistent plaques on light-exposed skin only (two patients), extension of lesions to nonexposed areas (four patients), or prolonged or persistent episodes o...

journal_title：Journal of the American Academy of Dermatology

authors： Toonstra J,Henquet CJ,van Weelden H,van der Putte SC,van Vloten WA

更新日期：1989-08-01 00:00:00

abstract：:Calcinosis cutis is the deposition of insoluble calcium salts in the skin and subcutaneous tissue. We report the case of a 28-year-old Caucasian woman with cystic fibrosis in whom strikingly symmetrical and reticulate calcinosis cutis developed on the lower extremities, which was noted on histology to spare the eccrin...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman JS,Fulghum Walters R,Woosley J,Fine JD

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Epidermolysis bullosa simplex is a skin-blistering disorder caused by mutations in keratin (K)14 or K5. Treatment with nuclear factor (erythroid-derived 2)-like 2 inducer sulforaphane ameliorated skin blistering in Krt14-null mice, correlating with induction of K17. To be therapeutically useful for epidermol...

journal_title：Journal of the American Academy of Dermatology

authors： Kerns ML,Guss L,Fahey J,Cohen B,Hakim JM,Sung S,Lu RG,Coulombe PA

更新日期：2017-03-01 00:00:00

abstract：:Cutaneous leishmaniasis (oriental sore) is characterized by slowly evolving inflammatory lesion(s) that are nodular, noduloulcerative, or ulcerative and that heal spontaneously with scar(s) in 3 to 12 months. In the course of a comprehensive study of cutaneous leishmaniasis due to Leishmania major in an endemic focus ...

journal_title：Journal of the American Academy of Dermatology

authors： Kubba R,Al-Gindan Y,el-Hassan AM,Omer AH

更新日期：1987-06-01 00:00:00

abstract：:To evaluate the sensitivity of histologic criteria 396 hematoxylin-eosin-stained step sections of 150 randomly sampled thin malignant melanomas (tumor thickness, less than or equal to 1.5 mm; level of invasion, I-III) were analyzed. The highest sensitivity was determined for nuclear atypia (84%), followed by the asymm...

journal_title：Journal of the American Academy of Dermatology

authors： Stolz W,Schmoeckel C,Welkovich B,Braun-Falco O

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:There are subgroups of cutaneous squamous cell carcinoma (SCC) that have a higher risk for both regional and distant metastasis. When cutaneous SCC does metastasize, it typically spreads first to local nodal groups. Sentinel lymph node (SLN) localization has been successfully used to evaluate nodal metastasi...

journal_title：Journal of the American Academy of Dermatology

authors： Weisberg NK,Bertagnolli MM,Becker DS

更新日期：2000-09-01 00:00:00

abstract：:Blisters from five patients with porphyria cutanea tarda and two patients with drug-induced pseudoporphyria were examined by direct immunofluorescence and by immunofluorescence mapping with antibodies against laminin and type IV collagen to determine the level of subepidermal separation. Primary screening by direct im...

journal_title：Journal of the American Academy of Dermatology

authors： Dabski C,Beutner EH

更新日期：1991-07-01 00:00:00

abstract：:Skin specimens from five mummies were examined histologically. The specimens ranged in age from 2,000 to 3,200 years. Material from two mummies had carbonized and showed only amorphous debris. The histology of the three remaining skin fragments retained surprising histologic architectural detail. One specimen obtained...

journal_title：Journal of the American Academy of Dermatology

authors： Chapel TA,Mehregan AH,Reyman TA

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Actinic keratosis is a skin lesion that can progress to squamous cell carcinoma but cannot always be clinically distinguished from a squamous cell carcinoma. OBJECTIVE:The purpose of this article is to describe the clinical presentation of actinic keratoses and squamous cell carcinoma. METHODS:The author's...

journal_title：Journal of the American Academy of Dermatology

authors： Moy RL

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Acral vascular syndromes associated with malignancy have rarely been reported. OBJECTIVE:Our purpose was to assess the clinical and evolving features of paraneoplastic acral vascular syndromes. PATIENTS AND METHODS:Two cases of paraneoplastic gangrene are described and analyzed together with previously rep...

journal_title：Journal of the American Academy of Dermatology

authors： Poszepczynska-Guigné E,Viguier M,Chosidow O,Orcel B,Emmerich J,Dubertret L

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Treatment of chronic discoid lupus erythematosus (CDLE) with a pulsed dye laser (PDL) has shown promising results, although outcomes in previous studies were not validated and laser parameters were inconsistent. OBJECTIVE:We conducted an open prospective study to assess the efficacy and safety of PDL for th...

journal_title：Journal of the American Academy of Dermatology

authors： Erceg A,Bovenschen HJ,van de Kerkhof PC,de Jong EM,Seyger MM

更新日期：2009-04-01 00:00:00

abstract：:Thirty-two patients with acne completed a randomized, double-blind study using topical 1% clindamycin phosphate or its vehicle applied twice daily for 8 weeks for a study of its effects on the intestinal microflora. Two clindamycin patients and one vehicle patient had Clostridium difficile in stools prior to therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Siegle RJ,Fekety R,Sarbone PD,Finch RN,Deery HG,Voorhees JJ

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Total body photography (TBP) can facilitate identification of new and changing lesions. By confirming that particular nevi are stable, TBP may reduce nevus biopsies. OBJECTIVES:We sought to determine the number and rate of nevus biopsies before and after TBP, and the factors associated with increased biopsy...

journal_title：Journal of the American Academy of Dermatology

authors： Truong A,Strazzulla L,March J,Boucher KM,Nelson KC,Kim CC,Grossman D

更新日期：2016-07-01 00:00:00

abstract：:Disseminated histoplasmosis is being diagnosed more frequently in persons infected with the human immunodeficiency virus and is often the initial manifestation of the acquired immunodeficiency syndrome (AIDS). Disease-related cutaneous features of HIV-associated disseminated histoplasmosis are defined as mucocutaneous...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen PR,Bank DE,Silvers DN,Grossman ME

更新日期：1990-09-01 00:00:00

abstract：:Kathon CG, a cosmetics preservative containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, appears to be a frequent cause of contact dermatitis in Europe. In the United States, where Kathon CG was introduced some 5 years later, the use of this preservative system f...

journal_title：Journal of the American Academy of Dermatology

authors： de Groot AC,Weyland JW

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Olumacostat glasaretil (OG) inhibits acetyl-coenzyme A carboxylase, the enzyme responsible for the first, rate-limiting step in de novo fatty acid synthesis. OG inhibited in vitro human sebocyte lipid production and reduced in vivo sebaceous gland size in hamster ears. OBJECTIVES:Safety and efficacy of OG 7...

journal_title：Journal of the American Academy of Dermatology

authors： Bissonnette R,Poulin Y,Drew J,Hofland H,Tan J

更新日期：2017-01-01 00:00:00

abstract：:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely dermatologic topics. Commentaries from the Dialogues Editor-in-Chief, Warren R. Heymann, MD, are provided after each discussion as a topic summary. These highlights are prov...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：2004-07-01 00:00:00

abstract：:Recently, low-dose 5-fluorouracil/cisplatin induction concurrent with radiation (chemoradiation) has been reported to be effective for locally advanced squamous cell carcinoma of the otorhinolaryngologic and gynecologic regions. However, to date, this therapeutic option has not been evaluated for squamous cell carcino...

journal_title：Journal of the American Academy of Dermatology

authors： Fujisawa Y,Umebayashi Y,Ichikawa E,Kawachi Y,Otsuka F

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Comparing effectiveness of biologics in real-world settings will help inform treatment decisions. OBJECTIVES:We sought to compare therapeutic responses among patients initiating infliximab, adalimumab, or etanercept versus ustekinumab during the Psoriasis Longitudinal Assessment and Registry (PSOLAR). METH...

journal_title：Journal of the American Academy of Dermatology

authors： Strober BE,Bissonnette R,Fiorentino D,Kimball AB,Naldi L,Shear NH,Goyal K,Fakharzadeh S,Calabro S,Langholff W,You Y,Galindo C,Lee S,Lebwohl MG

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Often after biopsy a skin cancer appears to resolve clinically and a repeat biopsy may be done on the area in question before proceeding with further treatment. OBJECTIVE:Our purpose was to assess the value of a subsequent biopsy in the treatment of skin cancers previously diagnosed by biopsy results. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Torres A,Seeburger J,Robison D,Glogau R

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:In the United States, complementary and alternative medicine (CAM) is used for a variety of diseases, including those of the skin. An estimate of the prevalence of CAM use among adults with skin disease using the alternative health supplement of the 2002 National Health Interview Survey (NHIS) has been publi...

journal_title：Journal of the American Academy of Dermatology

authors： Fuhrmann T,Smith N,Tausk F

更新日期：2010-12-01 00:00:00