Superantigens in dermatology.

abstract：:Topical nitrogen mustard is an alkylating agent. Its efficacy in treating alopecia areata was reported in an uncontrolled study. We present a preliminary, half-head, controlled 16-week study showing that topical nitrogen mustard was of benefit in 1 of 6 patients treated with 50% to 100% scalp involvement. Another 4 pa...

journal_title：Journal of the American Academy of Dermatology

authors： Bernardo O,Tang L,Lui H,Shapiro J

更新日期：2003-08-01 00:00:00

abstract：:This report reflects the best data available at the time the report was prepared, but caution should be exercised in interpreting the data; the results of future studies may require alteration of the conclusions or recommendations set forth in this report. ...

journal_title：Journal of the American Academy of Dermatology

authors： Miller OF 3rd,Phillips TJ

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Psoriasis significantly impairs work productivity and daily activities. OBJECTIVES:We sought to examine the effects of adalimumab on psoriasis-related work productivity and activity impairment and associations between the impairment and psoriasis severity in patients with moderate to severe psoriasis. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Kimball AB,Yu AP,Signorovitch J,Xie J,Tsaneva M,Gupta SR,Bao Y,Mulani PM

更新日期：2012-02-01 00:00:00

abstract：:A case of Flegel's disease, or hyperkeratosis lenticularis perstans, is reported. This rare chronic disorder is characterized by asymptomatic hyperkeratotic papules, usually located on the lower extremities. Most reported cases have been from Europe. We report a case of hyperkeratosis lenticularis perstans from our in...

journal_title：Journal of the American Academy of Dermatology

authors： Pearson LH,Smith JG Jr,Chalker DK

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Telemedicine technology holds great promise for dermatologic health care delivery. However, the clinical outcomes of digital image consultations (teledermatology) must be compared with traditional clinic-based consultations. OBJECTIVE:Our purpose was to assess and compare the reliability and accuracy of der...

journal_title：Journal of the American Academy of Dermatology

authors： Whited JD,Hall RP,Simel DL,Foy ME,Stechuchak KM,Drugge RJ,Grichnik JM,Myers SA,Horner RD

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Hypopigmented macules have been described infrequently as a presenting form of mycosis fungoides (MF). OBJECTIVE:This study was designed to clarify general characteristics of a hypopigmented MF variant. METHODS:Seven new cases were investigated with the use of descriptive epidemiology techniques. Demograph...

journal_title：Journal of the American Academy of Dermatology

authors： Lambroza E,Cohen SR,Phelps R,Lebwohl M,Braverman IM,DiCostanzo D

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Photosensitivity (PS) in lupus erythematosus (LE) is frequently determined by patient report. OBJECTIVE:We sought to characterize self-reported PS in cutaneous LE (CLE). METHODS:The PS survey was used to classify subject responses into 5 phenotypes: direct sun-induced CLE flare (directCLE); general exacerb...

journal_title：Journal of the American Academy of Dermatology

authors： Foering K,Chang AY,Piette EW,Cucchiara A,Okawa J,Werth VP

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Junctional nevi are traditionally associated with children and younger patients. We noticed that these lesions are also often found in elderly patients. OBJECTIVE:We sought to determine if junctional nevi are found in all age groups. METHODS:All biopsy reports for junctional nevi for the year 2001 at the P...

journal_title：Journal of the American Academy of Dermatology

authors： Westhafer J,Gildea J,Klepeiss S,Clarke L,Helm K

更新日期：2007-05-01 00:00:00

abstract：:We describe a 48-year-old woman with a 12-year history of porphyria cutanea tarda who showed a remarkable exacerbation of her eruptions accompanied by high serum levels of iron and ferritin at menopause. As iron storage is known to be a triggering factor of porphyria cutanea tarda, the possible role of menstruation as...

journal_title：Journal of the American Academy of Dermatology

authors： Nishioka E,Funasaka Y,Bito T,Ito A,Tani M,Kawara A,Yoon S,Kondo M,Ichihashi M

更新日期：2003-09-01 00:00:00

abstract：:We present a case of cutaneous infection due to Cladophialophora bantiana, an agent of phaeohyphomycosis. The patient developed a nodule with pustule formation on the dorsum of the left hand; no trauma was reported. The lesion was successfully treated with itraconazole and surgical excision. Histopathologically, there...

journal_title：Journal of the American Academy of Dermatology

authors： Patterson JW,Warren NG,Kelly LW

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Skin pigmentation disorders in systemic sclerosis (SSc) have been sparsely described in the literature. Nevertheless, they could be a diagnostic and/or severity marker. OBJECTIVES:To assess the association between pigmentation disorders and systemic involvement in patients with SSc. METHODS:A total of 5 pa...

journal_title：Journal of the American Academy of Dermatology

authors： Leroy V,Henrot P,Barnetche T,Cario M,Darrigade AS,Manicki P,Doutre MS,Lazaro E,Constans J,Barcat D,Vernhes JP,Richez C,Taieb A,Truchetet ME,Seneschal J,Fédération Hospitalo-Universitaire–Aquitaine's Care and Research Organi

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The decision to perform Mohs micrographic surgery (MMS) or wide local excision (WLE) for eyelid sebaceous carcinoma (SC) is controversial. OBJECTIVE:To compare local recurrence, metastasis, and tumor-related mortality of patients with eyelid SC who were initially treated with MMS versus with WLE. METHODS:A...

journal_title：Journal of the American Academy of Dermatology

authors： Zhou C,Wu F,Chai P,Shi Y,Ye J,Shi X,Tan J,Ding Y,Luo Y,Esmaeli B,Jia R,Fan X

更新日期：2019-06-01 00:00:00

abstract：:The regulation of telemedicine in the United States is evolving, with new legislation expanding reimbursement and cross-state licensing capabilities. As telemedicine grows, communities with limited access to traditional dermatologic care may find a solution in teledermatology. A search of the medical literature and on...

journal_title：Journal of the American Academy of Dermatology

authors： Chuchvara N,Patel R,Srivastava R,Reilly C,Rao BK

更新日期：2020-04-01 00:00:00

abstract：:This study compares the histopathologic characteristics of photodistributed and nonphotodistributed lichenoid drug eruptions in 13 patients. Both types have been said to be, in an unknown proportion, different from idiopathic lichen planus in that they can involve the deep as well as the superficial plexus, can contai...

journal_title：Journal of the American Academy of Dermatology

authors： West AJ,Berger TG,LeBoit PE

更新日期：1990-10-01 00:00:00

abstract：:Mycobacterium avium complex, a common opportunistic pathogen among patients with AIDS, usually manifests as disseminated disease involving the lung, lymph nodes, and gastrointestinal tract. Primary cutaneous infections with M avium complex are extremely rare, and most cutaneous lesions are caused by dissemination. Cut...

journal_title：Journal of the American Academy of Dermatology

authors： Kayal JD,McCall CO

更新日期：2002-11-01 00:00:00

abstract：:Human papillomavirus (HPV) is responsible for common condyloma acuminata and a number of premalignant and malignant anogenital lesions. These conditions are of particular concern in immunocompromised individuals who have higher risk of malignant transformation and are more difficult to treat. This is part I of a two-p...

journal_title：Journal of the American Academy of Dermatology

authors： Gormley RH,Kovarik CL

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Symptomatic dermographism is the most common type of physical urticaria. It can be severe and poorly controlled with H1 antihistamines in some patients. Photochemotherapy (psoralen plus ultraviolet [UV] A) may help the itch of dermographism but the effect of narrowband (NB) UVB therapy has not been previousl...

journal_title：Journal of the American Academy of Dermatology

authors： Borzova E,Rutherford A,Konstantinou GN,Leslie KS,Grattan CE

更新日期：2008-11-01 00:00:00

abstract：:In patients with psoriasis, there is an increased availability of drugs for treatment. However, there are important questions about drug safety for mothers with psoriasis and their fetuses. Currently, there are limited safety data for many of the medications used. In this article, we review current pregnancy risk info...

journal_title：Journal of the American Academy of Dermatology

authors： Lam J,Polifka JE,Dohil MA

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:UVA induces tissue damage via the production of radical oxygen species. Adding antioxidants to UV filters in sunscreens is a novel photoprotective strategy. The topical application of antioxidants in sunscreen can potentially neutralize the UVA-induced free radicals. OBJECTIVES:We sought to assess the degre...

journal_title：Journal of the American Academy of Dermatology

authors： Wang SQ,Osterwalder U,Jung K

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Mouse studies show that tumor-derived prostaglandins and platelets promote melanoma progression and immune evasion. OBJECTIVE:Determine whether aspirin confers longer survival in patients with melanoma. METHODS:A retrospective cohort study of 1522 patients at Indiana University Health who had melanoma diag...

journal_title：Journal of the American Academy of Dermatology

authors： Rachidi S,Wallace K,Li H,Lautenschlaeger T,Li Z

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Classical dermatomyositis (CDM) patients display the hallmark cutaneous manifestations of dermatomyositis (DM), proximal muscle weakness, and laboratory evidence of myositis. The epidemiology and management of both adult-onset and juvenile-onset CDM has been well characterized. However, the clinical significa...

journal_title：Journal of the American Academy of Dermatology

authors： Gerami P,Schope JM,McDonald L,Walling HW,Sontheimer RD

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Epidemiology and patterns of antibiotic resistance for Staphylococcus aureus are changing in the United States. OBJECTIVE:We sought to determine the epidemiology and antibiotic susceptibility profiles in S aureus cutaneous infections in a pediatric dermatology tertiary health care facility in North Carolina...

journal_title：Journal of the American Academy of Dermatology

authors： Ortega-Loayza AG,Diamantis SA,Gilligan P,Morrell DS

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Hyperlipidemia has received little attention as a side effect of cyclosporine therapy for severe psoriasis. OBJECTIVE:We report changes in fasting serum lipids in patients treated with low-dose oral cyclosporine for psoriasis and discuss their significance. METHODS:Twenty-two patients with severe, recalcit...

journal_title：Journal of the American Academy of Dermatology

authors： Stiller MJ,Pak GH,Kenny C,Jondreau L,Davis I,Wachsman S,Shupack JL

更新日期：1992-09-01 00:00:00

abstract：:Several aspects of trichotillomania in childhood are described and discussed. Case records of twenty-one children not older than 15 years of age, who were seen in the previous 5 years, were examined. The female/male ratio was 2.5:1 (fifteen girls and six boys); the age range was 2 to 15 years. Although trichotillomani...

journal_title：Journal of the American Academy of Dermatology

authors： Oranje AP,Peereboom-Wynia JD,De Raeymaecker DM

更新日期：1986-10-01 00:00:00

abstract：:We describe a female patient with an acute purpuric and bullous eruption mainly affecting the lower aspect of the legs. Skin biopsy specimens demonstrated microvascular occlusions with fibrin thrombi but no dermal inflammation. Intermediate hyperhomocysteinemia and transient antiphospholipid antibodies were evidenced ...

journal_title：Journal of the American Academy of Dermatology

authors： Martin L,Armingaud P,Georgescu V,Matre F,Legac E,Estève E

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Only a few reports have been published on the long-term outcome of surgical excision of cutaneous squamous cell carcinoma (SCC). OBJECTIVE:Our purpose was to report the clinical findings and 5-year recurrence rate of all patients with cutaneous SCC treated with Mohs micrographic surgery (MMS) in Australia b...

journal_title：Journal of the American Academy of Dermatology

authors： Leibovitch I,Huilgol SC,Selva D,Hill D,Richards S,Paver R

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Lymphomatoid papulosis (LyP) is a cyclic papulonodular eruption that is clinically benign and histologically malignant. Association with hematologic neoplasias has been reported in 5% to 20% of all cases. OBJECTIVE:We sought to review the clinical and histopathologic features of LyP in pediatric patients. ...

journal_title：Journal of the American Academy of Dermatology

authors： de Souza A,Camilleri MJ,Wada DA,Appert DL,Gibson LE,el-Azhary RA

更新日期：2009-12-01 00:00:00

abstract：:Our objective was to determine the percutaneous absorption of hydrocortisone in psoriatic skin. [14C]-Hydrocortisone formulated as a 0.5% cream was applied to sharply defined erythematous plaques with silvery scales on the dorsal forearm of four hospitalized psoriatic patients. An average 2.32 +/- 1.4 (SD) percent of ...

journal_title：Journal of the American Academy of Dermatology

authors： Wester RC,Bucks DA,Maibach HI

更新日期：1983-05-01 00:00:00

abstract：:Talimogene laherparepvec (T-VEC) is an oncolytic virus based on herpes simplex virus type 1 approved for intralesional treatment of advanced melanoma. In this article, we review the clinical literature on T-VEC for advanced melanoma and provide a practical approach to using T-VEC in the dermatologic surgery and oncolo...

journal_title：Journal of the American Academy of Dermatology

authors： Haitz K,Khosravi H,Lin JY,Menge T,Nambudiri VE

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The appropriate classification of study designs is important for review and assessment of the relevant scientific literature as a basis for decision making; however, little is known about whether study designs have been appropriately reported in the dermatology literature. OBJECTIVE:We aimed to validate the...

journal_title：Journal of the American Academy of Dermatology

authors： Ohn J,Eun SJ,Kim DY,Park HS,Cho S,Yoon HS

更新日期：2018-08-01 00:00:00