Superantigens in dermatology.

abstract：:Aquagenic urticaria is a rare disorder characterized by the occurrence of pruritus and wheals after temporary contact with water. The familial occurrence of aquagenic urticaria over 3 generations is reported here in association with familial lactose intolerance, a condition in which the enzyme lactase encoded on chrom...

journal_title：Journal of the American Academy of Dermatology

authors： Treudler R,Tebbe B,Steinhoff M,Orfanos CE

更新日期：2002-10-01 00:00:00

abstract：:Fifteen patients with toxic epidermal necrolysis (TEN) were studied. In all of them the TEN was related to drug ingestion and believed to be drug-induced. The drugs implicated include pyrazolone derivatives, allopurinol, barbiturates, tetracycline, phenytoin, and penicillamine. Possible etiologic co-factors are infect...

journal_title：Journal of the American Academy of Dermatology

authors： Chan HL

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Most biopsy specimens of cicatricial (scarring) alopecia can be readily subclassified as lymphocytic versus neutrophilic, but specific diagnosis remains difficult, particularly when a late stage of the disease is sampled. OBJECTIVE:We sought to document patterns of scarring highlighted by elastic tissue sta...

journal_title：Journal of the American Academy of Dermatology

authors： Fung MA,Sharon VR,Ratnarathorn M,Konia TH,Barr KL,Mirmirani P

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The continuous increase in the US population older than 65 years and the chronic course of psoriasis make management of psoriasis in the elderly an important health care problem. OBJECTIVE:We sought to develop a treatment algorithm for patients with psoriasis who are older than 65 years. METHODS:A systemat...

journal_title：Journal of the American Academy of Dermatology

authors： Grozdev IS,Van Voorhees AS,Gottlieb AB,Hsu S,Lebwohl MG,Bebo BF Jr,Korman NJ,National Psoriasis Foundation.

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Psoriasis's effect on diabetes onset is well documented, but its effect on course of diabetes is poorly understood. OBJECTIVE:We sought to compare risks of developing microvascular and macrovascular complications between diabetic patients with and without psoriasis. METHODS:Adults with 2 or more diabetes d...

journal_title：Journal of the American Academy of Dermatology

authors： Armstrong AW,Guérin A,Sundaram M,Wu EQ,Faust ES,Ionescu-Ittu R,Mulani P

更新日期：2015-06-01 00:00:00

abstract：:Poison ivy, poison oak, and poison sumac are now classified in the genus Toxicodendron which is readily distinguished from Rhus. In the United States, there are two species of poison oak, Toxicodendron diversilobum (western poison oak) and Toxicodendron toxicarium (eastern poison oak). There are also two species of po...

journal_title：Journal of the American Academy of Dermatology

authors： Guin JD,Gillis WT,Beaman JH

更新日期：1981-01-01 00:00:00

abstract：:Malacoplakia, an inflammatory disease characterized by accumulations of phagocytic macrophages, occurs primarily in immunocompromised individuals. Cutaneous involvement is rare. Two men, each with a renal allograft, had expanding nodules on the temple and perianal area (case 1) and perianal, inguinal, and scrotal skin...

journal_title：Journal of the American Academy of Dermatology

authors： Lowitt MH,Kariniemi AL,Niemi KM,Kao GF

更新日期：1996-02-01 00:00:00

abstract：:We report the case of a 29-year-old transsexual who developed Mycobacterium abscessus infection after receiving intramammary liquid silicone injections in the nonphysician office setting. Our patient represents 1 of 14 confirmed and 11 suspected cases in New York City of M abscessus infection after illicit cosmetic pr...

journal_title：Journal of the American Academy of Dermatology

authors： Fox LP,Geyer AS,Husain S,Della-Latta P,Grossman ME

更新日期：2004-03-01 00:00:00

abstract：:This study was conducted to further evaluate the safety and efficacy of 3% topical minoxidil in the treatment of extensive alopecia areata. Patients were assigned to one of two treatment regimens in a double-blind manner. One group applied 3% minoxidil to the scalp twice daily for 64 weeks; the other group applied pla...

journal_title：Journal of the American Academy of Dermatology

authors： Price VH

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Skin ulcers are common vascular complications of systemic sclerosis (SSc). OBJECTIVE:The aim of the study was to identify clinical, biologic, and imaging parameters that constitute risk factors for the occurrence and persistence of skin ulcers. METHODS:One hundred thirty Italian SSc patients were examined ...

journal_title：Journal of the American Academy of Dermatology

authors： Alivernini S,De Santis M,Tolusso B,Mannocci A,Bosello SL,Peluso G,Pinnelli M,D'Antona G,La Torre G,Ferraccioli G

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Eosinophilic myositis/perimyositis (EM/P) are a group of rare idiopathic muscle disorders associated with eosinophilia. OBJECTIVE:We describe the frequency and spectrum of cutaneous manifestations in EM/P and compare them with the idiopathic hypereosinophilic syndrome (HES). METHODS:We review the literatur...

journal_title：Journal of the American Academy of Dermatology

authors： Trüeb RM,Pericin M,Winzeler B,Wüthrich B,Burg G

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:A wide array of miscellaneous agents is being studied for the treatment of atopic dermatitis (AD), including targeted topical, oral systemic, and biologic agents. OBJECTIVE:To review the known efficacy and safety to date for such agents being studied for the treatment of AD. METHODS:A nonsystematic review ...

journal_title：Journal of the American Academy of Dermatology

authors： Vakharia PP,Silverberg JI

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Some studies have purported to link isotretinoin prescribed for acne with the development of inflammatory bowel disease (IBD). OBJECTIVE:We sought to identify existence of disproportionate attorney-initiated reporting of isotretinoin-associated IBD in the Food and Drug Administration Adverse Event Reporting...

journal_title：Journal of the American Academy of Dermatology

authors： Stobaugh DJ,Deepak P,Ehrenpreis ED

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:The appropriate classification of study designs is important for review and assessment of the relevant scientific literature as a basis for decision making; however, little is known about whether study designs have been appropriately reported in the dermatology literature. OBJECTIVE:We aimed to validate the...

journal_title：Journal of the American Academy of Dermatology

authors： Ohn J,Eun SJ,Kim DY,Park HS,Cho S,Yoon HS

更新日期：2018-08-01 00:00:00

abstract：:We present two patients who developed granuloma annulare in the scars from previous herpes zoster. The development of granuloma annulare in herpes zoster scars may represent an atypical delayed hypersensitivity immune reaction to herpes zoster/varicella virus antigen(s) or a tissue antigen altered by the virus. ...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman SJ,Fox BJ,Albert HL

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:If not diagnosed earlier, chromoblastomycosis has a chronic evolutional course that may cause several problems, such as difficulty in managing therapy because of the recrudescent character of the disease, potential association with the growth of epidermoid carcinoma in affected regions, and poor quality of l...

journal_title：Journal of the American Academy of Dermatology

authors： Minotto R,Bernardi CD,Mallmann LF,Edelweiss MI,Scroferneker ML

更新日期：2001-04-01 00:00:00

abstract：:Erythematous papulonodules that resembled a malignant lymphoma developed in a 62-year-old man. Further examination revealed that he had primary myelofibrosis with cutaneous extramedullary hematopoiesis. All three marrow elements (myeloid, erythroid, and megakaryocytic series) were present in the skin lesions. Although...

journal_title：Journal of the American Academy of Dermatology

authors： Mizoguchi M,Kawa Y,Minami T,Nakayama H,Mizoguchi H

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Confirmation of mild bites caused by Loxosceles reclusa with swab testing has not been previously documented, to our knowledge. METHODS:We report a case using an enzyme-linked immunosorbent assay (ELISA) test. RESULTS:A lesion lacking necrosis or other specific signs of loxoscelism was confirmed by identif...

journal_title：Journal of the American Academy of Dermatology

authors： Stoecker WV,Green JA,Gomez HF

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Very low vitamin D levels have been noted in patients with a variety of autoimmune diseases. OBJECTIVE:To determine whether low vitamin D levels are associated with autoimmunity in the setting of vitiligo vulgaris. METHODS:A prospective cohort study was conducted on 45 consecutive patients with vitiligo vu...

journal_title：Journal of the American Academy of Dermatology

authors： Silverberg JI,Silverberg AI,Malka E,Silverberg NB

更新日期：2010-06-01 00:00:00

abstract：:A patient with symptomatic urticaria pigmentosa who responded to nifedipine therapy is reported. Relief from cold-induced urtication and flushing was obtained with 10 mg taken orally three times daily. Calcium influx is an early step in the degranulation of mast cells. We hypothesize that the beneficial effect of nife...

journal_title：Journal of the American Academy of Dermatology

authors： Fairley JA,Pentland AP,Voorhees JJ

更新日期：1984-10-01 00:00:00

abstract：:We describe a patient with hypereosinophilic syndrome, who had severe cutaneous eruptions. Immunohistochemical study revealed that dermal endothelial cells in the lesional skin of this patient expressed eotaxin, which indicates eotaxin plays a part in inducing eosinophil migration into cutaneous tissue in hypereosinop...

journal_title：Journal of the American Academy of Dermatology

authors： Tsunemi Y,Idezuki T,Nakamura K,Tamaki K

更新日期：2003-11-01 00:00:00

abstract：:Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unknown origin that is characterized clinically by annular patches with erythematous borders and hypopigmented centers and histologically by loss of elastic fibers and elastophagocytosis. We report a case of AEGCG in an 8-month-ol...

journal_title：Journal of the American Academy of Dermatology

authors： Lee HW,Lee MW,Choi JH,Moon KC,Koh JK

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Despite a lack of evidence that dysplastic nevi are precursors to melanoma, a large proportion of dermatologists continue to treat them as such. Emerging data suggest that histologic grading approach may result in many unnecessary excisions. OBJECTIVE:Using a nongrading approach to diagnosis of Clark/dyspla...

journal_title：Journal of the American Academy of Dermatology

authors： Lozeau DF,Farber MJ,Lee JB

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Dermatomyositis affects visible skin and causes disease symptoms that can affect patients' quality of life (QOL). METHODS:In all, 71 patients with dermatomyositis or dermatomyositis sine myositis completed two QOL measures (the Skindex-16 and the Dermatology Life Quality Index) and a visual analog scale for...

journal_title：Journal of the American Academy of Dermatology

authors： Hundley JL,Carroll CL,Lang W,Snively B,Yosipovitch G,Feldman SR,Jorizzo JL

更新日期：2006-02-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infection in children has emerged as a major, rapidly growing public health problem. The majority of children become infected by perinatal transmission of the virus from an infected mother. The disease is frequently associated with progressive neurologic dysfunction and with opportun...

journal_title：Journal of the American Academy of Dermatology

authors： Prose NS

更新日期：1990-06-01 00:00:00

abstract：:Calciphylaxis is a rare phenomenon of cutaneous necrosis that typically occurs in association with renal failure and has a poor prognosis. We report 5 new cases of calciphylaxis that illustrate the important clinical and histopathologic features of the disease. All patients had end-stage renal failure at the time that...

journal_title：Journal of the American Academy of Dermatology

authors： Oh DH,Eulau D,Tokugawa DA,McGuire JS,Kohler S

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Current knowledge of angiolymphoid hyperplasia with eosinophilia (ALHE) derives from retrospective reports and case series, leading to a nonevidence-based treatment approach. OBJECTIVE:We sought to systematically review the literature relating to cutaneous ALHE to estimate its epidemiology and treatment out...

journal_title：Journal of the American Academy of Dermatology

authors： Adler BL,Krausz AE,Minuti A,Silverberg JI,Lev-Tov H

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Necrobiotic xanthogranuloma (NXG) is a rare histiocytic disorder of unknown origin. OBJECTIVE:We conducted an investigation of skin biopsy specimens from 7 patients with NXG for the presence of Borrelia by focus-floating microscopy. METHODS:Focus-floating microscopy is a recently described, modified immuno...

journal_title：Journal of the American Academy of Dermatology

authors： Zelger B,Eisendle K,Mensing C,Zelger B

更新日期：2007-12-01 00:00:00

abstract：:Kathon CG, a cosmetics preservative containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, appears to be a frequent cause of contact dermatitis in Europe. In the United States, where Kathon CG was introduced some 5 years later, the use of this preservative system f...

journal_title：Journal of the American Academy of Dermatology

authors： de Groot AC,Weyland JW

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Drug-specific T cells are involved in the pathogenesis of cutaneous adverse drug reactions (CADRs). OBJECTIVE:We sought to evaluate the diagnostic role of in vitro drug-induced release of interferon gamma in CADRs. METHODS:The study group consisted of 36 patients with CADRs after intake of 106 drugs that w...

journal_title：Journal of the American Academy of Dermatology

authors： Halevy S,Cohen AD,Grossman N

更新日期：2005-02-01 00:00:00