WITHDRAWN: COVID and Biologics.

abstract：BACKGROUND:Overexpression of adhesion molecules in tissues of human neoplasms, including malignant melanoma, has been reported to be clinically relevant, but the predictive value of circulating adhesion molecules for clinical outcome and life expectancy in patients with primary malignant melanoma (PMM) and metastases o...

journal_title：Journal of the American Academy of Dermatology

authors： Schaider H,Rech-Weichselbraun I,Richtig E,Seidl H,Soyer HP,Smolle J,Kerl H

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Pigmented Spitz nevi have distinct clinical features but often may be difficult to differentiate from malignant melanoma by clinical criteria. OBJECTIVE:The purpose of this study was to use a new noninvasive diagnostic approach to improve the clinical diagnosis of Spitz nevi. METHODS:Epiluminescence micros...

journal_title：Journal of the American Academy of Dermatology

authors： Steiner A,Pehamberger H,Binder M,Wolff K

更新日期：1992-11-01 00:00:00

abstract：:Capecitabine, an oral fluoropyrimidine and 5-fluorouracil (FU) prodrug recently approved for the treatment of metastatic colon and breast cancer, is currently under investigation in patients with gastric cancer. It has the advantage of oral administration, and good tolerability with its activity being comparable with ...

journal_title：Journal of the American Academy of Dermatology

authors： Weger W,Kränke B,Gerger A,Salmhofer W,Aberer E

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Crystalline/chrysalis structures (CS) are white shiny streaks that can only be seen with polarized dermatoscopy. OBJECTIVES:We sought to estimate the prevalence and assess the clinical significance of CS in melanocytic and nonmelanocytic lesions. METHODS:This was a prospective observational study in which ...

journal_title：Journal of the American Academy of Dermatology

authors： Balagula Y,Braun RP,Rabinovitz HS,Dusza SW,Scope A,Liebman TN,Mordente I,Siamas K,Marghoob AA

更新日期：2012-08-01 00:00:00

abstract：:A newly recognized and well-described connective tissue disease, eosinophilia-myalgia syndrome, is thought to relate to L-tryptophan ingestion. The suspect L-tryptophan made in Japan has been distributed in Japan and in the United States. Different from many case reports of eosinophilia-myalgia syndrome in the United ...

journal_title：Journal of the American Academy of Dermatology

authors： Mizutani T,Mizutani H,Hashimoto K,Nakamura Y,Kishida M,Taniguchi H,Murata M,Kuzuhara S,Shimizu M

更新日期：1991-09-01 00:00:00

abstract：:The quest for effective strategies to treat obesity has propelled fat research into an exploration of the molecular processes that drive adipocyte formation, and hence body fat mass. The development of obesity is dependent on the coordinated interplay of adipocyte hypertrophy (increased fat cell size), adipocyte hyper...

journal_title：Journal of the American Academy of Dermatology

authors： Avram MM,Avram AS,James WD

更新日期：2007-03-01 00:00:00

abstract：:Chronic neutrophilic leukemia is an uncommon myeloproliferative disorder. We report a new case that fulfills the clinical and biologic criteria for such a diagnosis. The hematologic disease was revealed by a neutrophilic dermatosis that finally disappeared spontaneously after a duration of 1 year. Despite the lack of ...

journal_title：Journal of the American Academy of Dermatology

authors： Castanet J,Lacour JP,Garnier G,Perrin C,Taillan B,Fuzibet JG,Ortonne JP

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Rosacea is a chronic inflammatory skin disease. Inflammation plays a prominent role in atherosclerosis and its complications. OBJECTIVE:We sought to investigate the associations of rosacea with cardiovascular disease risk factors and cardiovascular diseases from a nationwide population-based database. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Hua TC,Chung PI,Chen YJ,Wu LC,Chen YD,Hwang CY,Chu SY,Chen CC,Lee DD,Chang YT,Liu HN

更新日期：2015-08-01 00:00:00

abstract：:This review focuses on some of the most common classes of parenteral and inhalational sedating agents used during cutaneous surgery. Emphasis also is placed on potential adverse effects and their treatments. ...

journal_title：Journal of the American Academy of Dermatology

authors： Weber PJ,Weber M,Dzubow LM

更新日期：1989-05-01 00:00:00

abstract：:The responses to aggressive gluten challenge of two dermatitis herpetiformis patients with normal gut mucosa and negative serum findings for IgA endomysial antibodies while on normal diets indicate that these patients have a latent gluten-sensitive enteropathy. This was shown further by the control of skin lesions in ...

journal_title：Journal of the American Academy of Dermatology

authors： Chorzelski TP,Rosinska D,Beutner EH,Sulej J,Kumar V

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Clinical and histopathologic assessment of pigmented skin lesions remains challenging even for experts. Differentiated and accurate noninvasive diagnostic modalities are highly desirable. OBJECTIVE:We sought to provide clinicians with such a tool. METHODS:A 2-gene classification method based on LINC00518 a...

journal_title：Journal of the American Academy of Dermatology

authors： Gerami P,Yao Z,Polsky D,Jansen B,Busam K,Ho J,Martini M,Ferris LK

更新日期：2017-01-01 00:00:00

abstract：:Tuberous sclerosis is characterized by epilepsy, mental retardation, and adenoma sebaceum. Computerized axial tomography (CAT) is a noninvasive laboratory test that can assist in the diagnosis of this syndrome radiologically. A positive CAT scan is often present before the calcifications are noted on skull x-rays and ...

journal_title：Journal of the American Academy of Dermatology

authors： Burkhart CG,El-Shaar A

更新日期：1981-01-01 00:00:00

abstract：:Unlike other mammals that molt hair seasonally, human beings have scalp hair follicles that exhibit an asynchronized pattern of cycling, with the growth and subsequent shedding of each hair being independent of others around it. This mosaic cycling behavior is established early and continues throughout life. We descri...

journal_title：Journal of the American Academy of Dermatology

authors： Thai KE,Sinclair RD

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis (ACD) to optical brighteners and enzymes in laundry detergents was the focus of numerous reports in the early 1970s. Subsequently, there has been little published on the incidence of allergic reactions to chemicals in laundry detergents. Nonetheless, consumers and physicians conti...

journal_title：Journal of the American Academy of Dermatology

authors： Belsito DV,Fransway AF,Fowler JF Jr,Sherertz EF,Maibach HI,Mark JG Jr,Mathias CG,Rietschel RL,Storrs FJ,Nethercott JR

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:The clinical studies of series of children with herpes zoster (HZ) are rather limited. OBJECTIVE:The purpose of this study was to evaluate the epidemiologic conditions, clinical manifestations, therapy, and outcome of HZ in children. METHODS:Twenty-one patients with HZ have been studied. Five patients who ...

journal_title：Journal of the American Academy of Dermatology

authors： Kakourou T,Theodoridou M,Mostrou G,Syriopoulou V,Papadogeorgaki H,Constantopoulos A

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:The reported efficacy of imiquimod for lentigo maligna varies widely, without consensus on tumor or treatment factors that can impact tumor clearance. OBJECTIVE:We sought to provide a more precise estimate of clearance rates in patients with lentigo maligna who are treated with imiquimod and to analyze fact...

journal_title：Journal of the American Academy of Dermatology

authors： Mora AN,Karia PS,Nguyen BM

更新日期：2015-08-01 00:00:00

abstract：:Hutchinson's sign, periungual extension of brown-black pigmentation from longitudinal melanonychia onto the proximal and lateral nailfolds, is an important indicator of subungual melanoma. However, experience has demonstrated that Hutchinson's sign, although valuable, is not an infallible predictor of melanoma. Periun...

journal_title：Journal of the American Academy of Dermatology

authors： Baran R,Kechijian P

更新日期：1996-01-01 00:00:00

abstract：:At the International Consensus Conference for Cutaneous T-Cell Lymphoma (CTCL) Treatment Recommendations (held in Boston, Massachusetts, Oct. 1 and 2, 1994), international experts were asked to assess where consensus existed and to identify areas that required clinical research. We review the epidemiology, pathology, ...

journal_title：Journal of the American Academy of Dermatology

authors： Demierre MF,Foss FM,Koh HK

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Trichoadenoma is a rare benign follicular tumor first described by Nikolowski 50 years ago. Both trichoadenoma and desmoplastic trichoepithelioma are composed of cords of epithelial cells and cornifying cysts embedded in sclerotic stroma. In trichoadenoma the cystic component predominates, while desmoplastic...

journal_title：Journal of the American Academy of Dermatology

authors： Shimanovich I,Krahl D,Rose C

更新日期：2010-02-01 00:00:00

abstract：:Unilateral dermatomal superficial telangiectasia (UDST) may be congenital or acquired. Acquired UDST may occur coincident with physiologic states of estrogen increase, including puberty and pregnancy in women and adrenarche in men. Acquired UDST may also occur in estrogenized pathologic states such as chronic hepatic ...

journal_title：Journal of the American Academy of Dermatology

authors： Wilkin JK,Smith JG Jr,Cullison DA,Peters GE,Rodriquez-Rigau LJ,Feucht CL

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Few data exist on the relationship between psoriasis and melanocytic lesions. OBJECTIVES:We sought to investigate number of melanocytic nevi in psoriatic patients compared with control subjects and its relationship with disease severity and treatment. METHODS:We performed a prospective study in 189 psoriat...

journal_title：Journal of the American Academy of Dermatology

authors： Di Cesare A,Riitano A,Suppa M,Fidanza R,Zangrilli A,Esposito M,Fargnoli MC,Chimenti S,Peris K

更新日期：2013-12-01 00:00:00

abstract：:One hundred three patients with acne vulgaris were randomly designated to receive either a topical formulation of erythromycin plus zinc or a topical solution of 1% clindamycin phosphate (Cleocin-T). The patients treated themselves twice daily and were examined at 3, 6, 9, and 12 weeks after the start of therapy. By w...

journal_title：Journal of the American Academy of Dermatology

authors： Schachner L,Pestana A,Kittles C

更新日期：1990-03-01 00:00:00

abstract：:Keratoacanthoma (KA) is currently considered a benign epithelial neoplasm. We report a patient with a lesion diagnosed as a KA that behaved aggressively like a squamous cell carcinoma (SCC). Similar reports are not uncommon in the literature. Because there are currently no criteria by which KA can be differentiated fr...

journal_title：Journal of the American Academy of Dermatology

authors： Goldenhersh MA,Olsen TG

更新日期：1984-02-01 00:00:00

abstract：:We report the first case of acral localized acquired cutis laxa. The skin laxity was preceded by swelling of the fingers and toes and by the appearance of papular urticaria. Dapsone therapy was effective in controlling the swelling. Examination of skin biopsy specimens showed fragmentation and almost total loss of ela...

journal_title：Journal of the American Academy of Dermatology

authors： Fisher BK,Page E,Hanna W

更新日期：1989-07-01 00:00:00

abstract：:Angiosarcoma that develops in areas of chronic lymphedema is also called Stewart-Treves syndrome. It usually appears in areas of lymphedema several years after mastectomy for breast carcinoma. Only 10% of these angiosarcomas occur in areas of chronic lymphedema as a result of another cause. We present a patient with e...

journal_title：Journal of the American Academy of Dermatology

authors： Hallel-Halevy D,Yerushalmi J,Grunwald MH,Avinoach I,Halevy S

更新日期：1999-08-01 00:00:00

abstract：:Anti-epiligrin cicatricial pemphigoid is an autoimmune subepithelial blistering disorder of mucous membranes and skin. By immunoblot analyses, sera of most patients with antiepiligrin cicatricial pemphigoid have been shown to react specifically with the alpha3 chain of laminin 5. We describe the first patient with ant...

journal_title：Journal of the American Academy of Dermatology

authors： Fujimoto W,Toi Y,Okazaki F,Lazarova Z,Yancey KB,Arata J

更新日期：1999-04-01 00:00:00

abstract：:Infantile acropustulosis (IA) is a syndrome characterized by recurrent crops of 1- to 2-mm intensely pruritic vesicopustules that are found primarily on the distal extremities of infants. It is reportedly responsive to sulfones and unresponsive to other therapy, but if left untreated spontaneously resolves at about 2 ...

journal_title：Journal of the American Academy of Dermatology

authors： Jennings JL,Burrows WM

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:The adult burden of atopic dermatitis (AD) is poorly characterized. OBJECTIVE:We sought to characterize AD burden in adults with moderate to severe disease from the patient's perspective. METHODS:Patient-reported outcomes collected at screening in a phase 2b clinical trial of dupilumab included pruritus nu...

journal_title：Journal of the American Academy of Dermatology

authors： Simpson EL,Bieber T,Eckert L,Wu R,Ardeleanu M,Graham NM,Pirozzi G,Mastey V

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Preventing fetal exposure to isotretinoin is an important public health goal. Since approval of isotretinoin (1982), the Food and Drug Administration has implemented several unsuccessful risk management programs aimed at preventing fetal exposure. The Kaiser Permanente isotretinoin risk management program in...

journal_title：Journal of the American Academy of Dermatology

authors： Cheetham TC,Wagner RA,Chiu G,Day JM,Yoshinaga MA,Wong L

更新日期：2006-09-01 00:00:00

abstract：:A concept of dichotomous types of segmental involvement of autosomal dominant skin disorders has recently been proposed. Among the different types of porokeratosis, disseminated superficial actinic porokeratosis is known to be an autosomal dominant skin disorder, and linear porokeratosis represents the segmental form ...

journal_title：Journal of the American Academy of Dermatology

authors： Freyschmidt-Paul P,Hoffmann R,König A,Happle R

更新日期：1999-10-01 00:00:00