Visual Acuity Testing for Telehealth Using Mobile Applications.

abstract：IMPORTANCE:The potential effect of treatments for diabetic macular edema (DME) on driving should be of value to patients and clinicians, such as ophthalmologists and other physicians, who treat patients with diabetes mellitus. OBJECTIVE:To determine the effect of ranibizumab on driving and patient-reported vision func...

journal_title：JAMA ophthalmology

authors： Bressler NM,Varma R,Mitchell P,Suñer IJ,Dolan C,Ward J,Ferreira A,Ehrlich JS,Turpcu A

更新日期：2016-02-01 00:00:00

abstract：Importance:To our knowledge, a set of well-defined diagnostic criteria is not yet developed for the diagnosis of Vogt-Koyanagi-Harada (VKH) disease. Objective:To develop and evaluate a set of diagnostic criteria for VKH disease using data from Chinese patients. Design, Setting, and Participants:This case-control stud...

journal_title：JAMA ophthalmology

authors： Yang P,Zhong Y,Du L,Chi W,Chen L,Zhang R,Zhang M,Wang H,Lu H,Yang L,Zhuang W,Yang Y,Xing L,Feng L,Jiang Z,Zhang X,Wang Y,Zhong H,Jiang L,Zhao C,Li F,Cao S,Liu X,Chen X,Shi Y,Zhao W,Kijlstra A

更新日期：2018-09-01 00:00:00

abstract：IMPORTANCE:There is a major lack of randomized controlled clinical trials evaluating the efficacy of prismatic treatments for hemianopia. Evidence for their effectiveness is mostly based on anecdotal case reports and open-label evaluations without a control condition. OBJECTIVE:To evaluate the efficacy of real relativ...

journal_title：JAMA ophthalmology

authors： Bowers AR,Keeney K,Peli E

更新日期：2014-02-01 00:00:00

abstract：Importance:Mobility limitations arising from vision impairment (VI) can result in loss of independence and reduced quality of life. However, few data are available on the association between VI and mobility limitations at a population-based level, particularly in Asian populations. Objective:To assess the association ...

journal_title：JAMA ophthalmology

authors： Fenwick EK,Ong PG,Man RE,Cheng CY,Sabanayagam C,Wong TY,Lamoureux EL

更新日期：2016-10-01 00:00:00

abstract：IMPORTANCE:Although anti-vascular endothelial growth factor treatment of neovascular age-related macular degeneration (AMD) results in improved vision overall, loss of substantial vision can occur. Understanding the processes that lead to loss of vision may lead to preventive strategies. OBJECTIVE:To determine the inc...

journal_title：JAMA ophthalmology

authors： Ying GS,Kim BJ,Maguire MG,Huang J,Daniel E,Jaffe GJ,Grunwald JE,Blinder KJ,Flaxel CJ,Rahhal F,Regillo C,Martin DF,CATT Research Group.

更新日期：2014-08-01 00:00:00

abstract：Importance:Although almost equal numbers of male and female medical students enter into ophthalmology residency programs, whether they have similar surgical experiences during training is unclear. Objective:To determine differences for cataract surgery and total procedural volume between male and female residents duri...

journal_title：JAMA ophthalmology

authors： Gong D,Winn BJ,Beal CJ,Blomquist PH,Chen RW,Culican SM,Dagi Glass LR,Domeracki GF,Goshe JM,Jones JK,Khouri AS,Legault GL,Martin TJ,Mitchell KT,Naseri A,Oetting TA,Olson JH,Pettey JH,Reinoso MA,Reynolds AL,Siatkows

更新日期：2019-07-18 00:00:00

abstract：Importance:Mutations in the myocilin (MYOC) gene are the most common molecularly defined cause of primary open-angle glaucoma that typically occurs in patients with high intraocular pressures (IOP). One MYOC mutation, p.Gln368Ter, has been associated with as many as 1.6% of primary open-angle glaucoma cases that had a ...

journal_title：JAMA ophthalmology

authors： Alward WLM,van der Heide C,Khanna CL,Roos BR,Sivaprasad S,Kam J,Ritch R,Lotery A,Igo RP Jr,Cooke Bailey JN,Stone EM,Scheetz TE,Kwon YH,Pasquale LR,Wiggs JL,Fingert JH,NEIGHBORHOOD Consortium.

更新日期：2019-05-01 00:00:00

abstract：IMPORTANCE:Children with a history of amblyopia, even if resolved, exhibit impaired visual-auditory integration and perceive speech differently. OBJECTIVE:To determine whether a history of amblyopia is associated with abnormal visual-auditory speech integration. DESIGN, SETTING, AND PARTICIPANTS:Retrospective observa...

journal_title：JAMA ophthalmology

authors： Burgmeier R,Desai RU,Farner KC,Tiano B,Lacey R,Volpe NJ,Mets MB

更新日期：2015-01-01 00:00:00

abstract：Importance:Visual acuity (VA) outcomes differ considerably among patients with neovascular age-related macular degeneration (nAMD) treated with anti-vascular endothelial growth factor (VEGF) drugs. Identification of pharmacogenetic associations may help clinicians understand the mechanisms underlying this variability a...

journal_title：JAMA ophthalmology

authors： Lorés-Motta L,Riaz M,Grunin M,Corominas J,van Asten F,Pauper M,Leenders M,Richardson AJ,Muether P,Cree AJ,Griffiths HL,Pham C,Belanger MC,Meester-Smoor MA,Ali M,Heid IM,Fritsche LG,Chakravarthy U,Gale R,McKibbin M,

更新日期：2018-08-01 00:00:00

abstract：IMPORTANCE:Macular telangiectasia type 2 is a bilateral disease with characteristic alterations of the macular capillary network and neural atrophy. Vascular and neurodegenerative hypotheses have been proposed to explain these clinical findings, but many questions regarding the pathogenesis remain. OBSERVATIONS:We rep...

journal_title：JAMA ophthalmology

authors： Gillies MC,Mehta H,Bird AC

更新日期：2015-08-01 00:00:00

abstract：IMPORTANCE:Visualization and interpretation of the optic nerve and retina are essential parts of most physical examinations. OBJECTIVE:To design and validate a smartphone-based retinal adapter enabling image capture and remote grading of the retina. DESIGN, SETTING, AND PARTICIPANTS:This validation study compared the...

journal_title：JAMA ophthalmology

authors： Bastawrous A,Giardini ME,Bolster NM,Peto T,Shah N,Livingstone IA,Weiss HA,Hu S,Rono H,Kuper H,Burton M

更新日期：2016-02-01 00:00:00

abstract：Importance:Optical coherence tomographic angiography (OCT-A) is able to visualize retinal microvasculature without the need for injection of fluorescein contrast dye. Nevertheless, it is only able to capture a limited view of macula and does not show leakage. Objectives:To evaluate the retinal microvasculature using O...

journal_title：JAMA ophthalmology

authors： Ting DSW,Tan GSW,Agrawal R,Yanagi Y,Sie NM,Wong CW,San Yeo IY,Lee SY,Cheung CMG,Wong TY

更新日期：2017-04-01 00:00:00

abstract：Importance:Knowledge of the incidence and progression of diabetic retinopathy (DR) after gastric bypass surgery (GBP) in patients with obesity and diabetes could guide the management of these patients. Objective:To investigate the incidence of diabetic ocular complications in patients with type 2 diabetes after GBP co...

journal_title：JAMA ophthalmology

authors： Åkerblom H,Franzén S,Zhou C,Morén Å,Ottosson J,Sundbom M,Eliasson B,Svensson AM,Granstam E

更新日期：2021-01-14 00:00:00

abstract：IMPORTANCE:We conducted a series of phase 1 clinical trials to elucidate the efficacy and safety of the selective Rho kinase inhibitor K-115 as a candidate drug for the treatment of glaucoma. We report the intraocular pressure (IOP)-lowering effects and safety of K-115 based on our results. OBJECTIVE:To study the IOP-...

journal_title：JAMA ophthalmology

authors： Tanihara H,Inoue T,Yamamoto T,Kuwayama Y,Abe H,Araie M,K-115 Clinical Study Group.

更新日期：2013-10-01 00:00:00

abstract：Importance:Macular edema (ME) is the leading cause of decreased visual acuity (VA) associated with retinal vein occlusion (RVO). Identifying factors associated with better outcomes in RVO eyes treated with anti-vascular endothelial growth factor (VEGF) therapy may provide information useful in counseling patients. Obj...

journal_title：JAMA ophthalmology

authors： Scott IU,VanVeldhuisen PC,Ip MS,Blodi BA,Oden NL,King J,Antoszyk AN,Peters MA,Tolentino M,SCORE2 Investigator Group.

更新日期：2017-06-01 00:00:00

abstract：IMPORTANCE:Schnabel cavernous degeneration (SCD) has been observed in eyes with uveal melanoma (UM), but, to our knowledge, a definitive study establishing the association between SCD and UM has not been conducted. OBJECTIVE:To explore an association between SCD and UM. DESIGN, SETTING, AND PARTICIPANTS:A historical ...

journal_title：JAMA ophthalmology

authors： Kanavi MR,Azari AA,Potter HD,Lee V,Albert DM

更新日期：2014-05-01 00:00:00

abstract：Importance:The Diabetic Retinopathy Clinical Research Network Protocol S randomized clinical trial results suggest that ranibizumab is a reasonable treatment alternative to panretinal photocoagulation (PRP) when managing proliferative diabetic retinopathy (PDR), with or without concomitant baseline diabetic macular ede...

journal_title：JAMA ophthalmology

authors： Hutton DW,Stein JD,Bressler NM,Jampol LM,Browning D,Glassman AR,Diabetic Retinopathy Clinical Research Network.

更新日期：2017-06-01 00:00:00

abstract：Importance:Certain features of the lamina cribrosa may be associated with increased risk of glaucoma progression. Objectives:To compare the rates of retinal nerve fiber layer (RNFL) thinning in patients with open-angle glaucoma with or without lamina cribrosa (LC) defects and to evaluate factors associated with the ra...

journal_title：JAMA ophthalmology

authors： Moghimi S,Zangwill LM,Manalastas PIC,Suh MH,Penteado RC,Hou H,Hasenstab K,Ghahari E,Bowd C,Weinreb RN

更新日期：2019-04-01 00:00:00

abstract：IMPORTANCE:To facilitate comparative clinical outcome research in low vision rehabilitation, we must use patient-centered measurements that reflect clinically meaningful changes in visual ability. OBJECTIVE:To quantify the effects of currently provided low vision rehabilitation (LVR) on patients who present for outpat...

journal_title：JAMA ophthalmology

authors： Goldstein JE,Jackson ML,Fox SM,Deremeik JT,Massof RW,Low Vision Research Network Study Group.

更新日期：2015-07-01 00:00:00

abstract：Importance:Given the estimates of increasing prevalence of myopia, especially in Asia, it is important to determine the current prevalence of myopia among populations of schoolchildren in Japan. Objective:To investigate the current prevalence rate of myopia and the association between environmental factors and myopia ...

journal_title：JAMA ophthalmology

authors： Yotsukura E,Torii H,Inokuchi M,Tokumura M,Uchino M,Nakamura K,Hyodo M,Mori K,Jiang X,Ikeda SI,Kondo S,Negishi K,Kurihara T,Tsubota K

更新日期：2019-08-15 00:00:00

abstract：Objective:To compare oral voriconazole with placebo in addition to topical antifungals in the treatment of filamentous fungal keratitis. Design, Setting, and Participants:The Mycotic Ulcer Treatment Trial II (MUTT II), a multicenter, double-masked, placebo-controlled, randomized clinical trial, was conducted in India ...

journal_title：JAMA ophthalmology

authors： Prajna NV,Krishnan T,Rajaraman R,Patel S,Srinivasan M,Das M,Ray KJ,O'Brien KS,Oldenburg CE,McLeod SD,Zegans ME,Porco TC,Acharya NR,Lietman TM,Rose-Nussbaumer J,Mycotic Ulcer Treatment Trial II Group.

更新日期：2016-12-01 00:00:00

abstract：Importance:Ocular manifestations and outcomes in children with confirmed coronavirus disease 2019 (COVID-19), relevant affecting factors, and differences in ocular disease between children and adults have yet to be fully understood. Objective:To investigate ocular manifestations and clinical characteristics of childre...

journal_title：JAMA ophthalmology

authors： Ma N,Li P,Wang X,Yu Y,Tan X,Chen P,Li S,Jiang F

更新日期：2020-10-01 00:00:00

abstract：Importance:Congenital stationary night blindness (CSNB) implies a stable condition, with the major symptom being nyctalopia present at birth. Pediatric clinical presentation and the course of different genetic subtypes of CSNB have not, to our knowledge, been well described in the era of molecular genetic diagnosis. O...

journal_title：JAMA ophthalmology

authors： Miraldi Utz V,Pfeifer W,Longmuir SQ,Olson RJ,Wang K,Drack AV

更新日期：2018-04-01 00:00:00

abstract：Importance:After long-duration spaceflight, morphological changes in the optic nerve head (ONH) and surrounding tissues have been reported. Objective:To develop methods to quantify ONH and surrounding tissue changes using preflight and postflight optical coherence tomographic scans of the ONH region. Design, Setting,...

journal_title：JAMA ophthalmology

authors： Patel N,Pass A,Mason S,Gibson CR,Otto C

更新日期：2018-02-01 00:00:00

abstract：Importance:The number and size of guttae increase over time in Fuchs endothelial corneal dystrophy (FECD); however, the association between these physical parameters and disease pathogenesis is unclear. Objective:To determine the role of guttae in corneal endothelial cell function. Design, Settings, and Participants:...

journal_title：JAMA ophthalmology

authors： Kocaba V,Katikireddy KR,Gipson I,Price MO,Price FW,Jurkunas UV

更新日期：2018-08-01 00:00:00

abstract：Importance:Most premature infants will not develop retinopathy of prematurity (ROP) of clinical relevance, yet screening evaluations often continue beyond hospital discharge, even for those infants without ROP. Objectives:To identify the characteristics of infants at low risk for ROP, for whom further postdischarge sc...

journal_title：JAMA ophthalmology

authors： Wade KC,Ying GS,Baumritter A,Gong A,Kemper AR,Quinn GE,e-ROP Cooperative Group.

更新日期：2019-02-01 00:00:00

abstract：Importance:Anti-vascular endothelial growth factor (anti-VEGF) is a breakthrough treatment for wet age-related macular degeneration (wAMD), the most common cause of blindness in western countries. Anti-VEGF treatment prevents vision loss and has been shown to produce vision gains lasting as long as 5 years. Although th...

journal_title：JAMA ophthalmology

authors： Mulligan K,Seabury SA,Dugel PU,Blim JF,Goldman DP,Humayun MS

更新日期：2019-11-14 00:00:00

abstract：IMPORTANCE:Increased lipofuscin accumulation is assumed to be an important factor in the pathogenesis of age-related macular degeneration (AMD), although direct evidence for this hypothesis is missing. OBJECTIVE:To quantitatively investigate lipofuscin-associated fundus autofluorescence (AF) in patients with early and...

journal_title：JAMA ophthalmology

authors： Gliem M,Müller PL,Finger RP,McGuinness MB,Holz FG,Charbel Issa P

更新日期：2016-07-01 00:00:00

abstract：Importance:Both primary and secondary forms of childhood glaucoma have many distinct causative mechanisms, and in many cases a cause is not immediately clear. The broad phenotypic spectrum of secondary glaucoma, particularly in individuals with variants in FOXC1 or PITX2 genes associated with Axenfeld-Rieger syndrome, ...

journal_title：JAMA ophthalmology

authors： Siggs OM,Souzeau E,Pasutto F,Dubowsky A,Smith JEH,Taranath D,Pater J,Rait JL,Narita A,Mauri L,Del Longo A,Reis A,Chappell A,Kearns LS,Staffieri SE,Elder JE,Ruddle JB,Hewitt AW,Burdon KP,Mackey DA,Craig JE

更新日期：2019-04-01 00:00:00

abstract：Importance:Given the rarity of posterior uveal melanoma in patients younger than 21 years, reporting clinical experience in this area has relevance. Objective:To describe the baseline clinical features, treatment, and clinical course of a group of patients younger than 21 years who have primary posterior uveal melanom...

journal_title：JAMA ophthalmology

authors： Fry MV,Augsburger JJ,Corrêa ZM

更新日期：2019-01-01 00:00:00