Urinary Urgency in the Elderly.

abstract：BACKGROUND:Being able to rise from a chair is an important daily life activity that requires sufficient lower extremity muscle power and postural control. OBJECTIVE:To assess the effects of an individually tailored intervention on the chair rise capacity of active and inactive community-dwelling older men and women. ...

journal_title：Gerontology

authors： Tikkanen P,Lönnroos E,Sipilä S,Nykänen I,Sulkava R,Hartikainen S

更新日期：2013-01-01 00:00:00

abstract：:A trypsin-type protease was purified to enzymatic homogeneity from human umbilical vein endothelial cells by sequential affinity chromatographies. The enzyme specifically hydrolyzed dibasic substrates with leucine at the P3 positions, but scarcely hydrolyzed the other substrates tested. The enzyme was strongly inhibit...

journal_title：Gerontology

authors： Kido H,Takeda M,Wakabayashi H,Tanaka S,Nishimura N,Takenaka M,Okada M

更新日期：1993-01-01 00:00:00

abstract：:100 consecutive endoscopies in elderly patients referred with symptoms after previous gastric surgery are reviewed. 57% showed positive findings, and the procedure was found particularly useful in making definitive diagnoses in patients presenting with dyspepsia and upper gastro-intestinal bleeding. The incidence of g...

journal_title：Gerontology

authors： Gibbins FJ,Gupta SD,Sen I

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Adults aged 65 years and older stand to benefit from the accumulating wealth of Internet-based health resources, including online interventions to assist in the self-management of chronic health conditions. However, concerns have been expressed that lesser Internet use and familiarity among older adults may ...

journal_title：Gerontology

authors： Crabb RM,Rafie S,Weingardt KR

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:The identification of modifiable health span-promoting factors is a public health priority. OBJECTIVE:To explore the socio-environmental, lifestyle, behavioural, and psychological determinants of a clinical phenotypic measure of biological ageing in the Singapore Longitudinal Ageing Study (SLAS) cohort. ...

journal_title：Gerontology

authors： Ng TP,Zhong X,Gao Q,Gwee X,Chua DQL,Larbi A

更新日期：2020-01-01 00:00:00

abstract：:A prospective study of post-operative morbidity in 258 elderly general surgical patients is reported. In 35% of patients no post-operative complications developed. Respiratory, wound and cardiac complications were the leading types of post-operative morbidity encountered, occurring in 39.5, 16.3, and 12.4% of patients...

journal_title：Gerontology

authors： Seymour DG,Pringle R

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The prevalence of aortic stenosis is nearly 20% in octogenarians. Aortic valve replacement (AVR) is the optimal therapy choice, yet many symptomatic patients are denied this beneficent technology. Whether mechanical or bioprosthetic, aortic valves are not a scarce resource and their safety, effectiveness and...

journal_title：Gerontology

authors： Bramstedt KA

更新日期：2003-01-01 00:00:00

abstract：:Older adults have surprisingly high levels of well-being, which has been referred to as a paradox in the past. Improved emotion regulation has been suggested to underlie these high levels of well-being. Later life is also a period with enhanced exposure to critical life events, and this comes with risks. During such t...

journal_title：Gerontology

authors： Brose A,Ebner-Priemer UW

更新日期：2015-01-01 00:00:00

abstract：:Aging is a complex biological phenomenon which involves progressive loss of different physiological functions of various tissues of living organisms. It is the inevitable fate of life and is a major risk factor for death and different pathological disorders. Based on a wide variety of studies performed in humans as we...

journal_title：Gerontology

authors： Chakravarti B,Chakravarti DN

更新日期：2007-01-01 00:00:00

abstract：:Patients over 65 years of age admitted to an ophthalmic ward were routinely screened in a standard way practiced in Geriatric Assessment Units. The previous drug therapy of all patients was particularly noted. A classification of the patients with undetected pathology was made and an attempt to categorise the percenta...

journal_title：Gerontology

authors： Andrews J,Pandita-Gunawardena ND,Suntharalingham M

更新日期：1977-01-01 00:00:00

abstract：:The usual features of Paget's disease of bone, e.g. large head, deafness due to involvement of the 8th cranial nerve and bowing of the legs are all well described in text books of medicine. However, some features such as platybasia with neurological deficit, involvement of the 2nd, 5th and 7th cranial nerves, hydrocep...

journal_title：Gerontology

authors： Chakravorty NK

更新日期：1978-01-01 00:00:00

abstract：:We performed 24-hour ambulatory electrocardiographic (Holter) examinations in 50 retired hospital workers (30 men, 20 women), aged 58-85 years (mean age +/- SD: 65.9 +/- 4.6 years), with a normal clinical history, physical examination and baseline ECG. There was a significant difference between daytime and nocturnal m...

journal_title：Gerontology

authors： Ribera JM,Cruz AJ,Zamorano JL,Pérez-Casar F

更新日期：1989-01-01 00:00:00

abstract：:In three mouse lineages it was found that during the 18- to 60-day interval after formalin fixation, brain weight was inversely proportional to the age at sacrifice, as was the decline in the weight of the brain during this period. In a second study using rat subjects it was confirmed that the aging difference is due ...

journal_title：Gerontology

authors： Douglas RJ,Clark GM,Truncer PC,Treneer CM

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Myostatin has been proposed as a candidate biomarker for frailty and sarcopenia. However, the relationship of myostatin with these conditions remains inconclusive. OBJECTIVE:To determine the association of serum myostatin concentration with body composition, physical fitness, physical activity level, and fr...

journal_title：Gerontology

authors： Arrieta H,Hervás G,Rezola-Pardo C,Ruiz-Litago F,Iturburu M,Yanguas JJ,Gil SM,Rodriguez-Larrad A,Irazusta J

更新日期：2019-01-01 00:00:00

abstract：:Caloric restriction (CR), has been shown to extend average and maximum lifespan in rodents and other animals as well as to delay a wide variety of manifestations of aging. The purpose of this study was to further elucidate the relationship between lipofuscin (LF) accumulation and the aging process by examining the eff...

journal_title：Gerontology

authors： Moore WA,Davey VA,Weindruch R,Walford R,Ivy GO

更新日期：1995-01-01 00:00:00

abstract：:For logarithmically growing cultures of the human diploid cell lines WI-38 and WI-26, there is an exponential increase in the fraction of cells not incorporating [3H]dT under conditions of continuous labelling. Thymidine uptake, phosphorylation and incorporation into DNA can be correlated with cell proliferation. In a...

journal_title：Gerontology

authors： Cristofalo VJ

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:It is known from clinical practice and observational studies that elderly patients with a diagnosis of inflammatory rheumatic diseases (IRD) bear a significantly increased risk for cardiovascular diseases such as coronary artery disease (CAD) and heart failure. The molecular mechanism, however, is still not ...

journal_title：Gerontology

authors： Bruton M,Hollan I,Xiao J,Lindroos E,Mikkelsen K,Rynning SE,Saatvedt K,Almdahl SM,Harris HE,Lundberg IE,Wick C

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Cognitively stimulating activities contribute to the accumulation of cognitive reserve that is proposed to be instrumental for maintaining cognitive functioning in aging. Adopting a novel, more general conceptual perspective including models of vulnerability, we argue that cognitive reserve may modify the lo...

journal_title：Gerontology

authors： Ihle A,Rimmele U,Oris M,Maurer J,Kliegel M

更新日期：2020-01-01 00:00:00

abstract：:The concentrations of noradrenaline and adrenaline were studied in specimens of the posterior tibial artery obtained from 18 subjects at postmortem examination. The mean noradrenaline concentration was 167 ng/g artery (range 17-449 ng/g) and the mean adrenaline concentration was 5 ng/g (range 0--21 ng/g). There was no...

journal_title：Gerontology

authors： Neubauer B,Christensen NJ

更新日期：1978-01-01 00:00:00

abstract：:The characteristics of long-stay patients (defined as those staying more than 6 months) have been studied in a prospective series of 2,405 admissions. 5.6% become long-stay patients and they were more likely to be women, to be readmissions, to have been admitted from an old people's home, to have been non-emergency ad...

journal_title：Gerontology

authors： Hodkinson I,Hodkinson HM

更新日期：1981-01-01 00:00:00

abstract：:The kinetics of cell proliferation and sister chromatid exchanges (SCE) were studied in blood lymphocytes treated by mitomycin C (MMC) in young and old human donors. In both the young and old donors MMC inhibited cell proliferation. Spontaneous SCE frequency was not age-dependent. In young donors, MMC induced a dose-r...

journal_title：Gerontology

authors： Musilová J,Michalová K,Pacovský V

更新日期：1984-01-01 00:00:00

abstract：:In mammals, aging is often viewed as a progressive decline in physiological competence with a corresponding inability to adapt to stressful stimulation. Several current theories of aging have implicated the sympathetic nervous system in many of the metabolic, cardiovascular and behavior changes which attend advancing ...

journal_title：Gerontology

authors： McCarty R

更新日期：1986-01-01 00:00:00

abstract：:Protein malnutrition is associated with a decreased febrile and acute phase response to infection and increased mortality. To elucidate a cause for this poor response, we assessed the effect of chronic protein malnutrition on monocyte production of the pyrogens interleukin-1 (IL-1) and tumor necrosis factor (TNF). Thi...

journal_title：Gerontology

authors： Bradley SF,Vibhagool A,Fabrick S,Terpenning MS,Kauffman CA

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Infections due to Streptococcus pneumoniae are the major cause of adult community-acquired pneumonia, especially in elderly persons with chronic medical conditions. Despite their well-documented efficacy against bacteraemic disease and deaths in the elderly population, pneumococcal polysaccharide vaccines ar...

journal_title：Gerontology

authors： Wagner C,Popp W,Posch M,Vlasich C,Rosenberger-Spitzy A

更新日期：2003-07-01 00:00:00

abstract：:Sera from 40 elderly individuals ranging in age from 60 to 94 years were tested for the presence of antibodies to varicella-zoster virus (VZV)-specific proteins. Sodium dodecylsulfate polyacrylamide gel electrophoresis analysis of lysates of VZV-infected BSC-1 cells labeled with either [35S]methionine or [3H]mannose a...

journal_title：Gerontology

authors： Vafai A,Mahalingam R,Zerbe G,Wellish M,Gilden DH

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Falls are a major cause of morbidity among older people. Multifaceted interventions may be effective in preventing falls and related fractures. OBJECTIVE:To evaluate the cost-effectiveness alongside the REducing Falls with Orthoses and a Multifaceted podiatry intervention (REFORM) trial. METHODS:REFORM was...

journal_title：Gerontology

authors： Corbacho B,Cockayne S,Fairhurst C,Hewitt CE,Hicks K,Kenan AM,Lamb SE,MacIntosh C,Menz HB,Redmond AC,Rodgers S,Scantlebury A,Watson J,Torgerson DJ,on behalf of the REFORM study.

更新日期：2018-01-01 00:00:00

abstract：:Although it is usually assumed that Lamarckian inheritance does not and cannot occur, molecular mechanisms by which non-mutational changes acquired in one generation can be transmitted to the next are now known. These mechanisms involve changes in chromatin structure, rather than changes in DNA base sequence. It is ar...

journal_title：Gerontology

authors： Jablonka E,Lamb MJ

更新日期：1990-01-01 00:00:00

abstract：:Adhesion molecules, such as leukocyte-function-associated antigen (LFA-1 or CD11a/CD18), intercellular adhesion molecule 1 (ICAM-1 or CD54) and Hermes antigen (HCAM or CD44), have important roles in many adhesive interactions involving cells of the immune system. Since it has been shown that many immunological alterat...

journal_title：Gerontology

authors： Chiricolo M,Morini MC,Mancini R,Beltrandi E,Belletti D,Conte R

更新日期：1995-01-01 00:00:00

abstract：:Glutamine synthetase (GS) activity was measured in whole brain, different brain areas, liver and heart of 23- to 26-month-old rats, and then compared to matched animals of 3 months. A significant increase of GS activity was found in whole brain (25%) of old rats, as well as in all brain areas studied, but particularly...

journal_title：Gerontology

authors： Cao Danh H,Strolin Benedetti M,Dostert P

更新日期：1985-01-01 00:00:00

abstract：:The specific activities of NAD-linked isocitric dehydrogenase were determined in hypothalamus, cerebellum, pons and medulla, striatum, midbrain, and cerebral cortex (which included the hippocampus) of the female Wistar rat. In ageing the specific activities of this enzyme were decreased in all regions. Chronic treatme...

journal_title：Gerontology

authors： Lai JC,Leung TK,Lim L

更新日期：1982-01-01 00:00:00