Care transitions: a leverage point for safe and effective medication use in older adults--a mini-review.

abstract：BACKGROUND:Diabetes is common in elderly persons and is highly prevalent in Mexican Americans. Little is known about factors associated with the incidence of diabetes complications. OBJECTIVE:To examine the social, demographic and health factors associated with a 7-year incidence of diabetes complications among older ...

journal_title：Gerontology

authors： Kaushik VP,Al Snih S,Ray LA,Raji MA,Markides KS,Goodwin JS

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Many falls in older adults occur during walking and result in lateral falls. The ability to perform a recovery step after balance perturbation determines whether a fall will occur. AIM:To investigate age-related changes in first recovery step kinematics and kinematic adaptations over a wide range of later...

journal_title：Gerontology

authors： Nachmani H,Shani G,Shapiro A,Melzer I

更新日期：2020-01-01 00:00:00

abstract：:Cell surface of chick fibroblasts were labelled by a short treatment with 125I in presence of lactoperoxidase. A glycoprotein (220,000 molec. wt) was iodinated and was present in a more exposed position or in greater amounts at the surface of old phase III cells compared to young phase II cells. The findings extend ou...

journal_title：Gerontology

authors： Courtois Y,Hughes RC

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:The chronological age is clearly the strongest risk factor for fractures or death. Age as a concept can be described exactly as chronological age. Age in relative terms can be described as biological age. OBJECTIVE:We postulated that, even without taking into account known or unknown comorbidity, an immedia...

journal_title：Gerontology

authors： Gerdhem P,Ringsberg K,Akesson K,Obrant KJ

更新日期：2004-09-01 00:00:00

abstract：:The purpose of this study was to examine the effects of a multifactorial memory training program designed for normal older adults. The multifactorial program involved the training of three components that are critical to memory functioning: recoding operations, attentional functions and relaxation. Two controls groups...

journal_title：Gerontology

authors： Stigsdotter A,Bäckman L

更新日期：1989-01-01 00:00:00

abstract：:The concentrations of noradrenaline and adrenaline were studied in specimens of the posterior tibial artery obtained from 18 subjects at postmortem examination. The mean noradrenaline concentration was 167 ng/g artery (range 17-449 ng/g) and the mean adrenaline concentration was 5 ng/g (range 0--21 ng/g). There was no...

journal_title：Gerontology

authors： Neubauer B,Christensen NJ

更新日期：1978-01-01 00:00:00

abstract：:A group of clinical senile dementia patients underwent a series of cerebrovascular examinations. Some of them were standard examinations (fundus oculi, electroencephalogram, rheoencephalogram, cerebral angiogram and pneumonencephalogram) while the others were studying regional cerebral blood flow (rCBF) and modificati...

journal_title：Gerontology

authors： Dekoninck WJ,Collard M,Noel G

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Previous studies have shown links between cognitive impairment and hypertension as well as mortality. However, combined effects of these two conditions on mortality have not been fully explored. OBJECTIVE:To assess the combined effect of cognitive impairment and hypertension on all-cause mortality among the...

journal_title：Gerontology

authors： Gombojav B,Yi SW,Sull JW,Nam CM,Ohrr H

更新日期：2011-01-01 00:00:00

abstract：:Various parameters of copulatory behavior were examined in intact and castrated testosterone-(T-)treated male rats of various ages ranging from 3 to 27 months. Serum T levels were controlled by subcutaneous implantation of different sizes of T-filled Silastic capsules at the time of castration. In intact male rats, sc...

journal_title：Gerontology

authors： Hsu HK,Hsu C,Yu JY,Peng MT

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Although foot pain has been linked to fall risk, contributions of pain severity, foot posture, or foot function are unclear. These factors were examined in a cohort of older adults. OBJECTIVE:The purpose of this study was to examine the associations of foot pain, severity of foot pain, and measures of foot ...

journal_title：Gerontology

authors： Awale A,Hagedorn TJ,Dufour AB,Menz HB,Casey VA,Hannan MT

更新日期：2017-01-01 00:00:00

abstract：:The kinetics of cell proliferation and sister chromatid exchanges (SCE) were studied in blood lymphocytes treated by mitomycin C (MMC) in young and old human donors. In both the young and old donors MMC inhibited cell proliferation. Spontaneous SCE frequency was not age-dependent. In young donors, MMC induced a dose-r...

journal_title：Gerontology

authors： Musilová J,Michalová K,Pacovský V

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:One of the earliest and most persistent inquiries in developmental psychology is that of the relative contributions of nature and nurture to human ontogeny. One way of studying this distinction is by doing cross-cultural studies, in which culture provides a powerful way to operationalize the influence of nur...

journal_title：Gerontology

authors： Luszcz M

更新日期：2006-01-01 00:00:00

abstract：:This paper critiques Brand and Markowitsch's viewpoint that the decision-making difficulties experienced by older adults during laboratory-based gambling tasks can be attributed to deficits in executive control and feedback operations. While Brand and Markowitsch provide an important platform with which to understand ...

journal_title：Gerontology

authors： McCarrey AC,Henry JD,Luszcz M

更新日期：2010-01-01 00:00:00

abstract：:Because the body composition effects of growth hormone and insulin-like growth factor-I (IGF-I) are opposite to those of advancing age, it has been hypothesized that the decreased activity of the growth hormone-IGF-I axis is partly responsible for the loss of bone and muscle mass that characterizes normal human aging....

journal_title：Gerontology

authors： Boonen S,Lesaffre E,Aerssens J,Pelemans W,Dequeker J,Bouillon R

更新日期：1996-01-01 00:00:00

abstract：:The effects of ovine corticotropin releasing factor (o-CRF) on the secretions of ACTH, cortisol, dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) were studied in the healthy young and elderly male individuals. o-CRF caused significant elevations of plasma ACTH, cortisol and DHEA concentrations...

journal_title：Gerontology

authors： Ohashi M,Fujio N,Kato K,Nawata H,Ibayashi H

更新日期：1986-01-01 00:00:00

abstract：AIM:To investigate acceptance and usage issues in relation to Telehealth products as used by frail older clients of the Transition Care Program and their carers. METHOD:The study design was a quasi-randomised controlled clinical trial. A stratified random sample of participants was allocated to one of five groups usin...

journal_title：Gerontology

authors： Wade R,Shaw K,Cartwright C

更新日期：2012-01-01 00:00:00

abstract：:To investigate the mechanisms of age-related decline in synthesis of adrenal androgen, we studied the contents of cortisol (F) and dehydroepiandrosterone (DHEA) and the amounts of cytochrome P450 17 alpha-hydroxylase (P450c17) mRNA and cytochrome P450 11 beta-hydroxylase (P450c11) mRNA in young (1 year old) and senesc...

journal_title：Gerontology

authors： Ogo A,Haji M,Ohashi M,Nawata H

更新日期：1991-01-01 00:00:00

abstract：:The influence of age and smoking on pharmacokinetics of pindolol and propranolol was investigated. Although there was a statistically significant difference in certain pharmacokinetic parameters (maximum plasma concentration, area under the curve, elimination constant and elimination half-life) between elderly patient...

journal_title：Gerontology

authors： Hitzenberger G,Fitscha P,Beveridge T,Nüesch E,Pacha W

更新日期：1982-01-01 00:00:00

abstract：:Historically, family ties have been understood as the primary source of support for aging adults, and past empirical and theoretical work has highlighted the tendency of older adults to focus on close family. However, in line with demographic changes and historical increases in the diversity of social structures, frie...

journal_title：Gerontology

authors： Fiori KL,Windsor TD,Huxhold O

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:It is known that growth factors play a role in ageing and atherogenesis, and insulin develops mitogenic activity in vitro. OBJECTIVES:This study focuses on the pathway by which insulin induces proliferation and mobility in vascular smooth muscle cells (SMCs) compared with that of insulin-like growth factor-...

journal_title：Gerontology

authors： Ruiz-Torres A,Lozano R,Melón J,Carraro R

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Future time perspective has been associated with subjective well-being, though depending on the line of research considered either an open-ended future time perspective or a limited future time perspective has been associated with high well-being. Most of this research however has conceptualized future time ...

journal_title：Gerontology

authors： Kozik P,Hoppmann CA,Gerstorf D

更新日期：2015-01-01 00:00:00

abstract：:During the past decade, controversy has raged about the necessity of renal biopsy for the management of the idiopathic nephrotic syndrome. The debate has centered on whether a precise diagnosis is imperative for steroid treatment or whether such therapy can be given blindly. The above question has not been addressed i...

journal_title：Gerontology

authors： Moran D,Korzets Z,Bernheim J,Bernheim J,Yaretzky A

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:Creutzfeldt-Jakob disease (CJD) is not only a disorder of the central nervous system but also affects the skeletal muscle. Subclinical skeletal muscle involvement, manifesting as hyper-creatine-kinase (CK)-emia, is rare. CASE REPORT:The patient, a 60-year-old male, developed progressive dementia, accompanie...

journal_title：Gerontology

authors： Finsterer J,Gelpi E

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Older adults are stereotypically considered to be risk averse compared to younger age groups, although meta-analyses on age and the influence of gain/loss framing on risky choices have not found empirical evidence for age differences in risk-taking. OBJECTIVE:The current study extends the investigation of a...

journal_title：Gerontology

authors： Best R,Freund AM

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Aging changes in different body system are well described, but few studies have considered the relationship between them. OBJECTIVE:The purpose of this study was, therefore, to investigate the interrelationships between markers of aging in different parts of the body. METHODS:A cross-sectional study design...

journal_title：Gerontology

authors： Aihie Sayer A,Osmond C,Briggs R,Cooper C

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Understanding comorbidity prevalence and the effects of comorbidities in older veterans with lower extremity amputations may aid in assessing patient outcomes, resource use, and facility-level quality of care. OBJECTIVES:To determine the degree to which adding outpatient to inpatient administrative data sou...

journal_title：Gerontology

authors： Kurichi JE,Stineman MG,Kwong PL,Bates BE,Reker DM

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Fall incidents and their negative outcomes represent a considerable problem in hospitals, especially in geriatric wards, and require implementation of strategies to prevent these undesirable events. For this reason, the College of Geriatrics, a body funded by the Belgian Government to set up quality improvem...

journal_title：Gerontology

authors： Coussement J,Dejaeger E,Lambert M,Van Den Noortgate N,De Paepe L,Boonen S,Schoevaerdts D,Milisen K

更新日期：2009-01-01 00:00:00

abstract：:A profound influence of steroidal (and possibly growth) hormone change during aging on the P-450 functions has been found in male rats. Direct and rapid autonomic nervous controls on glycogen metabolism in the liver is also greatly affected by aging. However, neither the responses of isolated rat hepatocyte preparatio...

journal_title：Gerontology

authors： Kitani K

更新日期：1988-01-01 00:00:00

abstract：:Tuberculosis is still a major cause of morbidity and mortality worldwide. Recent studies have suggested that even in the developed world its incidence in the elderly is increasing. Symptoms of active tuberculosis are non-specific and less pronounced in the elderly. Radiological features are more likely to be 'atypical...

journal_title：Gerontology

authors： Packham S

更新日期：2001-07-01 00:00:00

abstract：:Metabolic, endocrine and biochemical variables of female hamsters were studied to define age-related alterations in their characteristics. Endurance performance, aerobic capacity and metabolic fuels and hormones were measured and compared in young-adult (2-3 months) and old (16-17 months) hamsters to determine if the ...

journal_title：Gerontology

authors： Nichols JF,Borer KT

更新日期：1987-01-01 00:00:00