Surface labelling of senescent chick fibroblasts by lactoperoxidase-catalysed iodination.

Abstract:

:Cell surface of chick fibroblasts were labelled by a short treatment with 125I in presence of lactoperoxidase. A glycoprotein (220,000 molec. wt) was iodinated and was present in a more exposed position or in greater amounts at the surface of old phase III cells compared to young phase II cells. The findings extend our previous observations on cell surface modifications in in vitro senescing fibroblasts.

journal_name

Gerontology

journal_title

Gerontology

authors

Courtois Y,Hughes RC

doi

10.1159/000212149

subject

Has Abstract

pub_date

1976-01-01 00:00:00

pages

371-9

issue

5

eissn

0304-324X

issn

1423-0003

journal_volume

22

pub_type

杂志文章
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    abstract:BACKGROUND:Constipation and lower urinary tract symptoms (LUTS) very frequently occur in the elderly, and several reports have suggested that dysfunction in either one of these systems may affect the other. Most studies correlating rectal and bladder dysfunction, however, have been carried out in children or young wome...

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    authors: Charach G,Greenstein A,Rabinovich P,Groskopf I,Weintraub M

    更新日期:2001-03-01 00:00:00

  • Relationship among activities of daily living, apathy, and subjective well-being in elderly people living alone in a rural town.

    abstract:BACKGROUND:There are limited psychological data on the quality of life and activities of daily living among elderly Japanese who live alone. OBJECTIVE:The aim of this study was to examine the frequency of apathy and its correlation with activities of daily living and with subjective well-being in elderly people living...

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    pub_type: 杂志文章

    doi:10.1159/000022102

    authors: Yamashita K,Iijima K,Kobayashi S

    更新日期:1999-09-01 00:00:00

  • Autoantibodies of systemic rheumatic diseases in the healthy elderly.

    abstract::Antinuclear antibodies, anticardiolipin antibodies and IgM rheumatoid factor were determined in 300 healthy aged subjects, comparing their prevalence to that in 100 healthy subjects aged between 19 and 44 years and 352 patients under 65 years of age, affected by various systemic rheumatic diseases. Increased productio...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000213183

    authors: Ruffatti A,Rossi L,Calligaro A,Del Ross T,Lagni M,Marson P,Todesco S

    更新日期:1990-01-01 00:00:00

  • Urinary characteristics and infection in the very aged.

    abstract::In the course of a health survey covering 561 inhabitants of Tampere, Finland, aged 85 or over, morning urine specimens were studied. 82% of the participants were women. Significant bacteriuria was recorded in 27% of the subjects, 13% of the men and 30% of the women. Pyuria was recorded in 47% of the total material. R...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212664

    authors: Heinämäki P,Haavisto M,Mattila K,Rajala S

    更新日期:1984-01-01 00:00:00

  • Do subchondral bone changes exacerbate or precede articular cartilage destruction in osteoarthritis of the elderly?

    abstract::Research into the aetiology of osteoarthritis has for several decades been concentrated on the destruction of the articular cartilage, the initiating events being believed to be changes in the proteoglycans and subsequently in the supporting collagenous framework, whereafter the disease is irreversible. Recent evidenc...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000213866

    authors: Bailey AJ,Mansell JP

    更新日期:1997-01-01 00:00:00

  • Decreased plasma taurine in aged rats.

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    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000213171

    authors: Wallace DR,Dawson R Jr

    更新日期:1990-01-01 00:00:00

  • Pharmacokinetics of theophylline in young and elderly subjects.

    abstract::Theophylline kinetics were evaluated in 6 elderly (age 65-75 years) and 5 young (age 22-28 years), nonsmoking males following the oral administration of 200 mg of Elixophylline. Theophylline serum concentration in the postabsorptive phase declined in a monoexponential manner. Total body clearance, elimination half-lif...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212549

    authors: Blouin RA,Erwin WG,Foster TS,Scott S

    更新日期:1982-01-01 00:00:00

  • The symptomatic post-surgical stomach--an endoscopic review.

    abstract::100 consecutive endoscopies in elderly patients referred with symptoms after previous gastric surgery are reviewed. 57% showed positive findings, and the procedure was found particularly useful in making definitive diagnoses in patients presenting with dyspepsia and upper gastro-intestinal bleeding. The incidence of g...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212699

    authors: Gibbins FJ,Gupta SD,Sen I

    更新日期:1985-01-01 00:00:00

  • Cerebral vasoreactivity in senile dementia.

    abstract::A group of clinical senile dementia patients underwent a series of cerebrovascular examinations. Some of them were standard examinations (fundus oculi, electroencephalogram, rheoencephalogram, cerebral angiogram and pneumonencephalogram) while the others were studying regional cerebral blood flow (rCBF) and modificati...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212183

    authors: Dekoninck WJ,Collard M,Noel G

    更新日期:1977-01-01 00:00:00

  • Potential mechanisms contributing to decision-making difficulties in late adulthood.

    abstract::This paper critiques Brand and Markowitsch's viewpoint that the decision-making difficulties experienced by older adults during laboratory-based gambling tasks can be attributed to deficits in executive control and feedback operations. While Brand and Markowitsch provide an important platform with which to understand ...

    journal_title:Gerontology

    pub_type: 评论,杂志文章

    doi:10.1159/000275060

    authors: McCarrey AC,Henry JD,Luszcz M

    更新日期:2010-01-01 00:00:00

  • Cytoplasmic and nuclear binding of estradiol in the brain and pituitary of old female rats.

    abstract::The subcellular distribution of estradiol following the in vivo administration of 3H-estradiol, cytosol and nuclear estrogen receptor after in vitro incubation with 3H-estradiol were studied in young adult female rats (3-6 months old) and old female rats (over 18 months old). After intravenous injection of 3H-estradio...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212449

    authors: Jiang MJ,Peng MT

    更新日期:1981-01-01 00:00:00

  • Disorders in peripheral arterial system in asymptomatic elderly: plethysmographic semiology at rest, during postural, effort and pharmacological tests.

    abstract::The vascular system of 30 old asymptomatic patients (average age 62.5 years) was studied by reflection plethysmography. The plethysmogram (PTG) was recorded from the forefinger of the left hand at rest, during two postural tests (+45 degrees arm-up and -45 degrees arm-down), after physical work, and during the infusio...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212317

    authors: Strozzi C,Cocco G,Destro A,Padovan G,Abbasciano V,Tosatti S

    更新日期:1979-01-01 00:00:00

  • The role of anthropometry in the assessment of malnutrition in the hospitalized frail elderly.

    abstract::Although common among the hospitalized frail elderly, malnutrition is often unrecognized by clinicians, and its identification is fought with difficulty due to inadequate nutritional assessment methods and standards. This study compared the use of percent ideal body weight (%IBW) and anthropometry in the assessment of...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000213553

    authors: Lansey S,Waslien C,Mulvihill M,Fillit H

    更新日期:1993-01-01 00:00:00

  • Effects of long-term Hydergine administration on lipofuscin accumulation in senescent rat brain.

    abstract::The effects of ageing and of 6 months of Hydergine treatment on lipofuscin deposition within the cytoplasma of pyramidal neurons of rat prefrontal cortex, hippocampus (fields CA1 and CA3) and of Purkinje neurons were assessed microfluorimetrically. No lipofuscin autofluorescence was detected in the nerve cell populati...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212963

    authors: Amenta D,Ferrante F,Franch F,Amenta F

    更新日期:1988-01-01 00:00:00

  • Perception of Risk for Older Adults: Differences in Evaluations for Self versus Others and across Risk Domains.

    abstract:BACKGROUND AND OBJECTIVES:Proxy decision-making may be flawed by inaccurate perceptions of risk. This may be particularly true when older adults are the targets of the decisions, given the pervasive negative stereotypes about older adults. METHODS:In study 1, individuals aged 18- to 87 years (as target persons) as wel...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000494352

    authors: Rolison JJ,Hanoch Y,Freund AM

    更新日期:2019-01-01 00:00:00

  • Aging-related genes in mesenchymal stem cells: a mini-review.

    abstract::Adult stem cells in mammalian organs play pivotal roles in the maintenance and repair of these organs throughout the life of the adult and maintain the proper homeostasis of a tissue or organ. Among the adult stem cells described to date, mesenchymal stem cells (MSCs) are highlighted for clinical applications because ...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000353857

    authors: Yu KR,Kang KS

    更新日期:2013-01-01 00:00:00

  • Potassium changes with age.

    abstract::Measurements of total exchangeable potassium and total exchangeable sodium, total body water and extracellular fluid volumes were made in 69 patients aged 30-90+ years, using multiple isotope techniques. The patients were not suffering from any chronic disorder or having potassium or diuretic therapy and were consider...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212495

    authors: Cox JR,Shalaby WA

    更新日期:1981-01-01 00:00:00

  • L-tryptophan administration in L-dopa-induced hallucinations in elderly Parkinsonian patients.

    abstract::L-tryptophan (L-T) was added at a dose of 150-450 mg daily to eight Parkinsonian patients who developed visual hallucinations with paranoidal features under L-dopa (L-D) treatment (112.5-75 mg daily) in combination with alpha-methyldopa hydrazine (12.5-75 mg daily). In six patients L-T ameliorated the symptomatology b...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212220

    authors: Rabey JM,Vardi J,Askenazi JJ,Streifler M

    更新日期:1977-01-01 00:00:00

  • Correlates and moderators of change in subjective memory and memory performance: findings from the health and retirement study.

    abstract::Aging researchers have long been interested in understanding individuals' subjective perceptions of their own memory functioning. Previous research has shown that subjective memory ratings are partly based on memory performance but also reflect the influence of other factors, such as depressive symptoms. The aim of th...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000369010

    authors: Hülür G,Hertzog C,Pearman AM,Gerstorf D

    更新日期:2015-01-01 00:00:00

  • Growth in fishes.

    abstract::Fishes exhibit a 'determinate' type of growth in short-lived species of warmer regions and an 'indeterminate' type in long-lived species of colder regions. Growth is measured in units of length and weight and is best represented as the specific growth rate. The relationship between weight and length provides an index ...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000213581

    authors: Dutta H

    更新日期:1994-01-01 00:00:00

  • Recovery of functional impairment after acute illness and mortality: one-year follow-up study.

    abstract:BACKGROUND:Functional status in older people is a dynamic situation, which makes it necessary to evaluate functional capacity at different times to determinate their prognostic value. OBJECTIVE:To examine the association between functional status (baseline and change after acute illness) and mortality and functional c...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000193068

    authors: Baztán JJ,Gálvez CP,Socorro A

    更新日期:2009-01-01 00:00:00

  • Purification of a trypsin-type protease from human umbilical vein endothelial cells which is highly sensitive to the Kunitz inhibitor domain peptide of Alzheimer's disease amyloid protein precursor.

    abstract::A trypsin-type protease was purified to enzymatic homogeneity from human umbilical vein endothelial cells by sequential affinity chromatographies. The enzyme specifically hydrolyzed dibasic substrates with leucine at the P3 positions, but scarcely hydrolyzed the other substrates tested. The enzyme was strongly inhibit...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000213563

    authors: Kido H,Takeda M,Wakabayashi H,Tanaka S,Nishimura N,Takenaka M,Okada M

    更新日期:1993-01-01 00:00:00

  • Influence of age, disease and disability on anthropometric indices in elderly Chinese aged 70 years and above.

    abstract::To determine the influence of age, disease and other factors on anthropometric indices in elderly subjects aged 70 years and above, body mass index (BMI), arm muscle circumference (AMC), corrected arm muscle area (CAMA), fat-free mass (FFM) and total body fat (TBF) were determined in a random sample of 990 Chinese men...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000213679

    authors: Woo J,Ho SC,Sham A,Yuen YK,Chan SG

    更新日期:1995-01-01 00:00:00

  • Introduction. Back to nurture: cross-cultural research as a paradigm for understanding bio-cultural dynamics of cognitive ageing.

    abstract:BACKGROUND:One of the earliest and most persistent inquiries in developmental psychology is that of the relative contributions of nature and nurture to human ontogeny. One way of studying this distinction is by doing cross-cultural studies, in which culture provides a powerful way to operationalize the influence of nur...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000094610

    authors: Luszcz M

    更新日期:2006-01-01 00:00:00

  • A neuropathological study of dementia in nursing homes over a 17-year period, in Shimane Prefecture, Japan.

    abstract:BACKGROUND:In Japan, vascular dementia (VD) has been responsible for the majority of all dementia cases in both epidemiological and neuropathological studies. Recently, however, several epidemiological investigations have shown that the rate of VD has decreased and senile dementia of the Alzheimer type (SDAT) is now th...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000022054

    authors: Seno H,Ishino H,Inagaki T,Iijima M,Kaku K,Inata T

    更新日期:1999-01-01 00:00:00

  • A Guiding Nightlight Decreases Fear of Falling and Increases Sleep Quality of Community-Dwelling Older People: A Quantitative and Qualitative Evaluation.

    abstract:BACKGROUND:Even though poor lighting at nighttime is an important risk factor for falls (and most falls occur during the night), lighting interventions to improve nightly lighting from bed to bathroom are rarely evaluated for fall prevention. OBJECTIVE:We tested the hypothesis that an automated guiding light would red...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000504883

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  • Effects of aging on formalin-fixed brain weight in mice and rats.

    abstract::In three mouse lineages it was found that during the 18- to 60-day interval after formalin fixation, brain weight was inversely proportional to the age at sacrifice, as was the decline in the weight of the brain during this period. In a second study using rat subjects it was confirmed that the aging difference is due ...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212460

    authors: Douglas RJ,Clark GM,Truncer PC,Treneer CM

    更新日期:1981-01-01 00:00:00

  • Inducible nitric oxide synthase-activated mitochondrial apoptotic pathway in hypoxic and aged rat hearts.

    abstract:BACKGROUND:Hypoxia and aging determine on mammalian cells a stress response which implies modified production of oxidants, reactive oxygen species or reactive nitrogen species at the mitochondrial level, interfering with cell-signaling proteins and inducing mitochondrial damage, apoptosis occurrence and functional cons...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000299105

    authors: Zara S,Rapino M,Centurione L,di Giacomo V,Petruccelli G,Cataldi A

    更新日期:2010-01-01 00:00:00

  • Cardiac surgery in nonagenarians: single-centre series and review.

    abstract:BACKGROUND:Cardiac surgery is widely believed to be an excessively high-risk intervention for very elderly patients with coronary artery or valvular disease. However, as life expectancy and the prospect of sustained quality of life into older age increase, this assumption should be challenged so that surgery is not den...

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    pub_type: 杂志文章,评审

    doi:10.1159/000271602

    authors: Guilfoyle MR,Drain AJ,Khan A,Ferguson J,Large SR,Nashef SA

    更新日期:2010-01-01 00:00:00

  • Thymus and aging: potential of gene therapy for restoration of endocrine thymic function in thymus-deficient animal models.

    abstract:OBJECTIVE AND BACKGROUND:The aim of the present article is to discuss the potential of gene therapy for thymic hormones as a novel therapeutic strategy to treat dyshomeostatic states associated with athymia, as Di George syndrome, or hypothymic conditions like those associated with AIDS, chronic stress or aging. First ...

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    pub_type: 杂志文章

    doi:10.1159/000065258

    authors: Goya RG,Cónsole G,Hereñú C,Brown O,Rimoldi OJ

    更新日期:2002-09-01 00:00:00