Physiological, metabolic and running characteristics of senescent female hamsters.

Abstract:

:Metabolic, endocrine and biochemical variables of female hamsters were studied to define age-related alterations in their characteristics. Endurance performance, aerobic capacity and metabolic fuels and hormones were measured and compared in young-adult (2-3 months) and old (16-17 months) hamsters to determine if the storage of substrates used in endurance exercise is altered with age, and if so, its effect on performance. The results indicate that storage of metabolic fuels are not appreciably altered with age, although voluntary running is markedly reduced. Other factors are likely involved in the hypoactivity of senescent female hamsters.

journal_name

Gerontology

journal_title

Gerontology

authors

Nichols JF,Borer KT

doi

10.1159/000212902

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

349-56

issue

6

eissn

0304-324X

issn

1423-0003

journal_volume

33

pub_type

杂志文章
  • Waist circumference adds to the variance in plasma C-reactive protein levels in elderly patients with metabolic syndrome.

    abstract:BACKGROUND:C-reactive protein (CRP), a nonspecific marker of the inflammatory status, is associated with cardiovascular disease risk factors and may be an important feature of the metabolic syndrome (MSX) in middle-aged subjects. OBJECTIVES:We assessed the relationship of CRP levels to specific components of MSX and o...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000103555

    authors: Dupuy AM,Jaussent I,Lacroux A,Durant R,Cristol JP,Delcourt C

    更新日期:2007-01-01 00:00:00

  • Potential mechanisms contributing to decision-making difficulties in late adulthood.

    abstract::This paper critiques Brand and Markowitsch's viewpoint that the decision-making difficulties experienced by older adults during laboratory-based gambling tasks can be attributed to deficits in executive control and feedback operations. While Brand and Markowitsch provide an important platform with which to understand ...

    journal_title:Gerontology

    pub_type: 评论,杂志文章

    doi:10.1159/000275060

    authors: McCarrey AC,Henry JD,Luszcz M

    更新日期:2010-01-01 00:00:00

  • The long-stay patient.

    abstract::The characteristics of long-stay patients (defined as those staying more than 6 months) have been studied in a prospective series of 2,405 admissions. 5.6% become long-stay patients and they were more likely to be women, to be readmissions, to have been admitted from an old people's home, to have been non-emergency ad...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212467

    authors: Hodkinson I,Hodkinson HM

    更新日期:1981-01-01 00:00:00

  • Foot Function, Foot Pain, and Falls in Older Adults: The Framingham Foot Study.

    abstract:BACKGROUND:Although foot pain has been linked to fall risk, contributions of pain severity, foot posture, or foot function are unclear. These factors were examined in a cohort of older adults. OBJECTIVE:The purpose of this study was to examine the associations of foot pain, severity of foot pain, and measures of foot ...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000475710

    authors: Awale A,Hagedorn TJ,Dufour AB,Menz HB,Casey VA,Hannan MT

    更新日期:2017-01-01 00:00:00

  • Effects of age and turpentine-induced inflammation on the activity of ceruloplasmin from blood of CFY rats.

    abstract::The activity of ceruloplasmin (CP) increased 3-fold in rat blood between 1 week and 20 months of age, but the difference in CP activity of adult and old rats was only 14%, which still is statistically significant (p less than 0.01). The increase in NaCl and KCl concentrations in vitro resulted in the same exponential ...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000213261

    authors: Semsei I

    更新日期:1991-01-01 00:00:00

  • Determination of malonaldehyde in Alzheimer's disease: a comparative study of high-performance liquid chromatography and thiobarbituric acid test.

    abstract::The concentration of malonaldehyde (MDA) was measured in human erythrocytes obtained from subjects suffering from senile dementia of the Alzheimer type (SDAT), non-demented elderly subjects, and from young controls by two methods: high-performance liquid chromatography (HPLC) and the thiobarbituric acid (TBA) test. Th...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000213853

    authors: Bermejo P,Gómez-Serranillos P,Santos J,Pastor E,Gil P,Martín-Aragón S

    更新日期:1997-01-01 00:00:00

  • Thymidine labelling index as a criterion of aging in vitro.

    abstract::For logarithmically growing cultures of the human diploid cell lines WI-38 and WI-26, there is an exponential increase in the fraction of cells not incorporating [3H]dT under conditions of continuous labelling. Thymidine uptake, phosphorylation and incorporation into DNA can be correlated with cell proliferation. In a...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212122

    authors: Cristofalo VJ

    更新日期:1976-01-01 00:00:00

  • Development of a Home Health Patient Assessment Tool for Disaster Planning.

    abstract:BACKGROUND:Historically, older adults have been disproportionately affected by disasters. In particular, homebound adults are especially at risk. As one facet of bolstering community resilience, home health agencies have been tasked with improving their patients' disaster preparedness. However, home health practitioner...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000494971

    authors: Wyte-Lake T,Claver M,Tubbesing S,Davis D,Dobalian A

    更新日期:2019-01-01 00:00:00

  • Age-related difference in the response of plasma erythropoietin to hemorrhage in ovariectomized rats.

    abstract::The effect of aging on plasma erythropoietin (EPO) levels after acute hemorrhage was investigated in ovariectomized (Ovx) rats. Old (22 months), middle (mid)-aged (14 months) and adult (5-6 months) Ovx rats were studied. Rats were anesthetized with ether and bled by heart puncture (5 ml/kg). They were bled again after...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000213666

    authors: Wang RY,Tung YF,Wang PS

    更新日期:1995-01-01 00:00:00

  • Tuberculosis in the elderly.

    abstract::Tuberculosis is still a major cause of morbidity and mortality worldwide. Recent studies have suggested that even in the developed world its incidence in the elderly is increasing. Symptoms of active tuberculosis are non-specific and less pronounced in the elderly. Radiological features are more likely to be 'atypical...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000052794

    authors: Packham S

    更新日期:2001-07-01 00:00:00

  • Is renal biopsy justified for the diagnosis and management of the nephrotic syndrome in the elderly?

    abstract::During the past decade, controversy has raged about the necessity of renal biopsy for the management of the idiopathic nephrotic syndrome. The debate has centered on whether a precise diagnosis is imperative for steroid treatment or whether such therapy can be given blindly. The above question has not been addressed i...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000213514

    authors: Moran D,Korzets Z,Bernheim J,Bernheim J,Yaretzky A

    更新日期:1993-01-01 00:00:00

  • Impact of pneumococcal vaccination on morbidity and mortality of geriatric patients: a case-controlled study.

    abstract:BACKGROUND:Infections due to Streptococcus pneumoniae are the major cause of adult community-acquired pneumonia, especially in elderly persons with chronic medical conditions. Despite their well-documented efficacy against bacteraemic disease and deaths in the elderly population, pneumococcal polysaccharide vaccines ar...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000070405

    authors: Wagner C,Popp W,Posch M,Vlasich C,Rosenberger-Spitzy A

    更新日期:2003-07-01 00:00:00

  • Some unusual features of Paget's disease of bone.

    abstract::The usual features of Paget's disease of bone, e.g. large head, deafness due to involvement of the 8th cranial nerve and bowing of the legs are all well described in text books of medicine. However, some features such as platybasia with neurological deficit, involvement of the 2nd, 5th and 7th cranial nerves, hydrocep...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212286

    authors: Chakravorty NK

    更新日期:1978-01-01 00:00:00

  • Ageing of the skin: study of elastic fiber network modifications by computerized image analysis.

    abstract::We quantitated the skin elastic fibers of the papillary and reticular dermis using specific staining procedure followed by automated computerized image analysis. Fifty skin biopsies of patients consulting for cardiovascular risk factors were studied. The following parameters were estimated: surface area (% of total su...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212969

    authors: Robert C,Lesty C,Robert AM

    更新日期:1988-01-01 00:00:00

  • Role of stress granules and RNA-binding proteins in neurodegeneration: a mini-review.

    abstract::The eukaryotic stress response involves translational suppression of non-housekeeping proteins and the sequestration of unnecessary mRNA transcripts into stress granules (SGs). This process is dependent on mRNA-binding proteins (RBPs) that interact with capped mRNA transcripts through RNA recognition motifs, and exhib...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000354170

    authors: Vanderweyde T,Youmans K,Liu-Yesucevitz L,Wolozin B

    更新日期:2013-01-01 00:00:00

  • Do subchondral bone changes exacerbate or precede articular cartilage destruction in osteoarthritis of the elderly?

    abstract::Research into the aetiology of osteoarthritis has for several decades been concentrated on the destruction of the articular cartilage, the initiating events being believed to be changes in the proteoglycans and subsequently in the supporting collagenous framework, whereafter the disease is irreversible. Recent evidenc...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000213866

    authors: Bailey AJ,Mansell JP

    更新日期:1997-01-01 00:00:00

  • How can we not 'lose it' if we still don't understand how to 'use it'? Unanswered questions about the influence of activity participation on cognitive performance in older age--a mini-review.

    abstract::The 'use it or lose it' hypothesis of cognitive aging predicts that engagement in intellectual, social, and physical activities offers protective benefits from age-related cognitive decline and lowers dementia risk. Although this hypothesis has not yet been supported conclusively, there is some empirical evidence in f...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000264918

    authors: Bielak AA

    更新日期:2010-01-01 00:00:00

  • Principles of control and selection in mammalian aging.

    abstract::Acquisition of immunologic self-tolerance by clonal deletion in the thymus is concluded to be a critical process in immune aging and is found to be transiently protected from genetic instability by means of a feedback surveillance which functions at the expense of chronic thymic involution. In the immune control of ma...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000213604

    authors: Hartwig M

    更新日期:1994-01-01 00:00:00

  • Study of age changes in the motor units of the first dorsal interosseous muscle in man.

    abstract::The effect of ageing on the threshold firing rate of motor units from the first dorsal interosseous muscle was investigated. Two groups of 9 healthy male subjects between the ages of 20-29 and 60-69 years took part in the study. The threshold firing rate of motor units in young subjects showed close agreement with pre...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212939

    authors: Newton JP,Yemm R,McDonagh MJ

    更新日期:1988-01-01 00:00:00

  • Predictors of improvement or decline in instrumental activities of daily living among community-dwelling older Japanese.

    abstract:BACKGROUND:To explore predictors of functional improvement or decline in instrumental activities of daily living (IADL) among community-dwelling older people. METHODS:Of all the residents (>or=65 years, n = 1,673) living in Yoita town, Niigata prefecture, Japan, in 2000, 1,544 subjects who participated in the baseline...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000151221

    authors: Fujiwara Y,Yoshida H,Amano H,Fukaya T,Liang J,Uchida H,Shinkai S

    更新日期:2008-01-01 00:00:00

  • Urinary Urgency in the Elderly.

    abstract::The last 2 decades have brought an explosion of research, new products, and general attention to the problem of urinary urgency, and yet patients continue to be plagued by this symptom - especially the elderly. What is it? What does it mean? How can we guide patients successfully through this challenge? This paper pre...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000492330

    authors: Potts JM,Payne CK

    更新日期:2018-01-01 00:00:00

  • Multifactorial memory training with older adults: how to foster maintenance of improved performance.

    abstract::The purpose of this study was to examine the effects of a multifactorial memory training program designed for normal older adults. The multifactorial program involved the training of three components that are critical to memory functioning: recoding operations, attentional functions and relaxation. Two controls groups...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000213035

    authors: Stigsdotter A,Bäckman L

    更新日期:1989-01-01 00:00:00

  • Characteristics of the phagocytically induced respiratory burst in leukocytes from young adult and aged beagle dogs.

    abstract::Phagocytically stimulated canine leukocyte suspensions obtained from 12 young adult and 43 aged individuals were examined for several physiological manifestations of the phagocytically induced respiratory burst. There was considerable variation in levels of oxygen consumption, glucose oxidation via the hexose monophos...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212625

    authors: Johnson DD,Renshaw HW,Warner DH,Browder EJ,Williams JD

    更新日期:1984-01-01 00:00:00

  • Expression of High Mobility Group Protein B1 in Cardiac Tissue of Elderly Patients with Coronary Artery Disease with or without Inflammatory Rheumatic Disease.

    abstract:BACKGROUND:It is known from clinical practice and observational studies that elderly patients with a diagnosis of inflammatory rheumatic diseases (IRD) bear a significantly increased risk for cardiovascular diseases such as coronary artery disease (CAD) and heart failure. The molecular mechanism, however, is still not ...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000471763

    authors: Bruton M,Hollan I,Xiao J,Lindroos E,Mikkelsen K,Rynning SE,Saatvedt K,Almdahl SM,Harris HE,Lundberg IE,Wick C

    更新日期:2017-01-01 00:00:00

  • Can atherosclerosis regress? The role of the vascular extracellular matrix and the age-related changes of arteries.

    abstract:BACKGROUND:Previous extensive clinical studies, using angiography or ultrasound, investigated the influence of alimentary, medicamentous and other antiatherosclerotic measures on the degree of atherosclerosis. The following signs of regression were found: clinical improvement, changes in tonus of vascular walls, format...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000065248

    authors: Kunz J

    更新日期:2002-09-01 00:00:00

  • Life Expectancy: Frequently Used, but Hardly Understood.

    abstract::Period life expectancy is one of the most used summary indicators for the overall health of a population. Its levels and trends direct health policies, and researchers try to identify the determining risk factors to assess and forecast future developments. The use of period life expectancy is often based on the assump...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000500955

    authors: Luy M,Di Giulio P,Di Lego V,Lazarevič P,Sauerberg M

    更新日期:2020-01-01 00:00:00

  • The Increasing Importance of Friendship in Late Life: Understanding the Role of Sociohistorical Context in Social Development.

    abstract::Historically, family ties have been understood as the primary source of support for aging adults, and past empirical and theoretical work has highlighted the tendency of older adults to focus on close family. However, in line with demographic changes and historical increases in the diversity of social structures, frie...

    journal_title:Gerontology

    pub_type: 杂志文章,评审

    doi:10.1159/000505547

    authors: Fiori KL,Windsor TD,Huxhold O

    更新日期:2020-01-01 00:00:00

  • Systemic diseases in association with microbial species in oral biofilm from elderly requiring care.

    abstract:BACKGROUND:The oral cavity is a reservoir for colonization and infection of systemic organs by pathogenic bacteria. It is understood that aging, tooth eruption, hormonal changes, active disease, oral hygiene, and other factors have an influence on biofilm formation and bacterial accumulation in the oral cavity. OBJECT...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000071711

    authors: Senpuku H,Sogame A,Inoshita E,Tsuha Y,Miyazaki H,Hanada N

    更新日期:2003-09-01 00:00:00

  • Urinary characteristics and infection in the very aged.

    abstract::In the course of a health survey covering 561 inhabitants of Tampere, Finland, aged 85 or over, morning urine specimens were studied. 82% of the participants were women. Significant bacteriuria was recorded in 27% of the subjects, 13% of the men and 30% of the women. Pyuria was recorded in 47% of the total material. R...

    journal_title:Gerontology

    pub_type: 杂志文章

    doi:10.1159/000212664

    authors: Heinämäki P,Haavisto M,Mattila K,Rajala S

    更新日期:1984-01-01 00:00:00

  • Evidence-based guidelines for the secondary prevention of falls in older adults.

    abstract:BACKGROUND:Falls are a significant problem for older adults. Individuals who have sustained a fall come to the attention of health care providers and are at risk of further falls. To promote the highest quality of care and reduce variation in care, a practice guideline is needed. Summarization of evidence regarding fal...

    journal_title:Gerontology

    pub_type: 杂志文章,meta分析

    doi:10.1159/000067948

    authors: Moreland J,Richardson J,Chan D,O'Neill J,Bellissimo A,Grum R,Shanks L

    更新日期:2003-03-01 00:00:00