Is renal biopsy justified for the diagnosis and management of the nephrotic syndrome in the elderly?

abstract：:The biological rhythms of rectal temperature were documented in young (circadian variations) and elderly (circadian and seasonal variations) human subjects either in apparent good health or suffering from senile dementia of Alzheimer type (SDAT). All the subjects were synchronized. Data obtained showed a decrease of t...

journal_title：Gerontology

authors： Touitou Y,Reinberg A,Bogdan A,Auzéby A,Beck H,Touitou C

更新日期：1986-01-01 00:00:00

abstract：:This paper critiques Brand and Markowitsch's viewpoint that the decision-making difficulties experienced by older adults during laboratory-based gambling tasks can be attributed to deficits in executive control and feedback operations. While Brand and Markowitsch provide an important platform with which to understand ...

journal_title：Gerontology

authors： McCarrey AC,Henry JD,Luszcz M

更新日期：2010-01-01 00:00:00

abstract：:The influence of age and smoking on pharmacokinetics of pindolol and propranolol was investigated. Although there was a statistically significant difference in certain pharmacokinetic parameters (maximum plasma concentration, area under the curve, elimination constant and elimination half-life) between elderly patient...

journal_title：Gerontology

authors： Hitzenberger G,Fitscha P,Beveridge T,Nüesch E,Pacha W

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:The oral cavity is a reservoir for colonization and infection of systemic organs by pathogenic bacteria. It is understood that aging, tooth eruption, hormonal changes, active disease, oral hygiene, and other factors have an influence on biofilm formation and bacterial accumulation in the oral cavity. OBJECT...

journal_title：Gerontology

authors： Senpuku H,Sogame A,Inoshita E,Tsuha Y,Miyazaki H,Hanada N

更新日期：2003-09-01 00:00:00

abstract：:Constant exposure to new and persisting antigens and the need to replace cellular attrition with newly built cells lead to profound remodeling of the immune system after the age of 50 years. The impact of the immunosenescence process varies amongst the different cellular subsets represented within the immune system. E...

journal_title：Gerontology

authors： Jagger A,Shimojima Y,Goronzy JJ,Weyand CM

更新日期：2014-01-01 00:00:00

abstract：:The effect of ageing on the threshold firing rate of motor units from the first dorsal interosseous muscle was investigated. Two groups of 9 healthy male subjects between the ages of 20-29 and 60-69 years took part in the study. The threshold firing rate of motor units in young subjects showed close agreement with pre...

journal_title：Gerontology

authors： Newton JP,Yemm R,McDonagh MJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Old age has traditionally been considered to begin at age 65. The improving health and functional status observed among older people may necessitate reevaluation of this cut-off point. OBJECTIVE:To present the changing prevalence of common geriatric syndromes, functional parameters, common disease status an...

journal_title：Gerontology

authors： Jacobs JM,Maaravi Y,Cohen A,Bursztyn M,Ein-Mor E,Stessman J

更新日期：2012-01-01 00:00:00

abstract：:We have shown that ultrastructural changes accompany ageing in the human fetal lung fibroblast strain MRC-5. In order to further characterise these changes a method has been devised to prepare subcellular fractions from MRC-5 fibroblasts using a discontinous gradient of metrizamide preceded by a low-speed centrifugati...

journal_title：Gerontology

authors： Shakespeare VA,Buchanan JH

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Fall incidents and their negative outcomes represent a considerable problem in hospitals, especially in geriatric wards, and require implementation of strategies to prevent these undesirable events. For this reason, the College of Geriatrics, a body funded by the Belgian Government to set up quality improvem...

journal_title：Gerontology

authors： Coussement J,Dejaeger E,Lambert M,Van Den Noortgate N,De Paepe L,Boonen S,Schoevaerdts D,Milisen K

更新日期：2009-01-01 00:00:00

abstract：:In the United States, an increasing proportion of all forms of reactivation tuberculosis occurs in patients over the age of 60 years. Atypical presentations and presence of chronic illness obscure the diagnosis of tuberculosis in the elderly. Prompt diagnosis requires a high index of suspicion and aggressive procedure...

journal_title：Gerontology

authors： Nagami P,Yoshikawa TT

更新日期：1984-01-01 00:00:00

abstract：:Some authors have hypothesised that life expectancy at birth could reach 100 years in developed countries in the next decades. Using recent data for French women, it is shown that life expectancy changes from 1993 to 2016 are mainly linked to mortality rates of oldest women. In recent years, it happened that life expe...

journal_title：Gerontology

authors： Le Bourg E

更新日期：2019-01-01 00:00:00

abstract：:We use nerve tissue cultures as a model system for studying the mode of action of centrally acting drugs. Neurons in cerebellar cultures retain a number of organ-specific properties including the formation of complex synaptic networks and characteristic bioelectric activity. Electrical activity may be recorded from Pu...

journal_title：Gerontology

authors： Gähwiler BH

更新日期：1978-01-01 00:00:00

abstract：:The immunocompetence of 22 subjects aged 85-104 years (mean 90 +/- 1 years) was studied and compared to 21 young subjects aged 19-37 years (mean 30 +/- 1 years). The absolute lymphocyte number and the percentage of T and B lymphocytes in the peripheral blood was similar in the two groups. A marked decrease in phytohem...

journal_title：Gerontology

authors： Licastro F,Tabacchi PL,Chiricolo M,Parente R,Cenci M,Barboni F,Franceschi C

更新日期：1983-01-01 00:00:00

abstract：:Differences between women and men in terms of gender gaps at late stages of their lives are the focus of this mini-review. We approach the matter by taking up the position of complex yet promising standpoints, the bio-psycho-social perspective on the one hand and approaches of developmental psychology on the other. Li...

journal_title：Gerontology

authors： Kryspin-Exner I,Lamplmayr E,Felnhofer A

更新日期：2011-01-01 00:00:00

abstract：:Adhesion molecules, such as leukocyte-function-associated antigen (LFA-1 or CD11a/CD18), intercellular adhesion molecule 1 (ICAM-1 or CD54) and Hermes antigen (HCAM or CD44), have important roles in many adhesive interactions involving cells of the immune system. Since it has been shown that many immunological alterat...

journal_title：Gerontology

authors： Chiricolo M,Morini MC,Mancini R,Beltrandi E,Belletti D,Conte R

更新日期：1995-01-01 00:00:00

abstract：:Both ageing and vitamin C (VC) deficiency result in immune defect. Since low serum and tissue levels of VC are found in the elderly, we have in a placebo-controlled study, tested the effect of VC supplements (500 mg/day i.m. for 1 month) on various immune parameters. Indeed, VC enhances the proliferative response of T...

journal_title：Gerontology

authors： Kennes B,Dumont I,Brohee D,Hubert C,Neve P

更新日期：1983-01-01 00:00:00

abstract：:To investigate the mechanisms of age-related decline in synthesis of adrenal androgen, we studied the contents of cortisol (F) and dehydroepiandrosterone (DHEA) and the amounts of cytochrome P450 17 alpha-hydroxylase (P450c17) mRNA and cytochrome P450 11 beta-hydroxylase (P450c11) mRNA in young (1 year old) and senesc...

journal_title：Gerontology

authors： Ogo A,Haji M,Ohashi M,Nawata H

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Reference values are usually defined based on blood samples from healthy men or nonpregnant women in the age range of 20-50 years. These values are not optimal for elderly patients, as many biological markers change over time and adequate reference values are important for correct clinical decisions. OBJECT...

journal_title：Gerontology

authors： Carlsson L,Lind L,Larsson A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Nerve growth factor (NGF), discovered because of its action on cells in the peripheral and the central nervous system, is now known to act also on immune cells in developing and adult subjects. Whether peripheral lymphocytes of aged subjects are responsive to this molecule is less clear. OBJECTIVE:Aim of ou...

journal_title：Gerontology

authors： Antonelli A,Bracci-Laudiero L,Aloe L

更新日期：2003-05-01 00:00:00

abstract：:Cyclic AMP-dependent and -independent protein kinase have been isolated from livers of rats at 3, 9, 18 and 30 months of age. A preliminary characterization reported here reveals that in addition to a decrease in their activities due to ageing and a likely shift to cyclic AMP-independent casein kinase activity at 30 m...

journal_title：Gerontology

authors： Kumar R,Chiero L,Rodriguez D

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Perceived stress may be a modifiable risk factor for mild cognitive impairment (MCI) and ultimately dementia, but studies on this topic from low- and middle-income countries (LMICs) are lacking. OBJECTIVE:We assessed the association between perceived stress and MCI in six LMICs (China, Ghana, India, Mexico,...

journal_title：Gerontology

authors： Koyanagi A,Oh H,Vancampfort D,Carvalho AF,Veronese N,Stubbs B,Lara E

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Disturbance of vertical eye movement and ocular convergence is often observed in elderly people, but little is known about its frequency. OBJECTIVE:The purpose of this study was to investigate age-associated changes in vertical eye movement and convergence in healthy elderly people, using a digital video ca...

journal_title：Gerontology

authors： Oguro H,Okada K,Suyama N,Yamashita K,Yamaguchi S,Kobayashi S

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Relationships between alcohol consumption and risks for metabolic syndrome in general populations are very controversial. It is unknown whether age influences the relationship between alcohol intake and the prevalence of metabolic syndrome. OBJECTIVE:The purpose of this study was to determine whether age in...

journal_title：Gerontology

authors： Wakabayashi I

更新日期：2012-01-01 00:00:00

abstract：:The Zika virus (ZIKV) outbreak in French Polynesia, in 2013, and in Brazil, in 2015, was correlated with neurological complications, which comprised, among others, congenital microcephaly and Guillain-Barré syndrome (GBS), which includes a group of acute autoimmune neuropathies generally reported after respiratory or ...

journal_title：Gerontology

authors： Savino W,Messias CV,Mendes-da-Cruz DA,Passos P,Ferreira AC,Nascimento OJ

更新日期：2017-01-01 00:00:00

abstract：:The kinetics of cell proliferation and sister chromatid exchanges (SCE) were studied in blood lymphocytes treated by mitomycin C (MMC) in young and old human donors. In both the young and old donors MMC inhibited cell proliferation. Spontaneous SCE frequency was not age-dependent. In young donors, MMC induced a dose-r...

journal_title：Gerontology

authors： Musilová J,Michalová K,Pacovský V

更新日期：1984-01-01 00:00:00

abstract：:Because the body composition effects of growth hormone and insulin-like growth factor-I (IGF-I) are opposite to those of advancing age, it has been hypothesized that the decreased activity of the growth hormone-IGF-I axis is partly responsible for the loss of bone and muscle mass that characterizes normal human aging....

journal_title：Gerontology

authors： Boonen S,Lesaffre E,Aerssens J,Pelemans W,Dequeker J,Bouillon R

更新日期：1996-01-01 00:00:00

abstract：:The distribution of sister chromatid exchange (SCE) points has been analyzed in cultured lymphocytes from three age-groups of 30 females (n = 10; young: 13-20, middle-aged: 30-55, old: 75-84 years). The observed interchromosomal SCE distribution is in good agreement with the results of previous workers, significant ag...

journal_title：Gerontology

authors： Vormittag W

更新日期：1983-01-01 00:00:00

abstract：AIM:To investigate acceptance and usage issues in relation to Telehealth products as used by frail older clients of the Transition Care Program and their carers. METHOD:The study design was a quasi-randomised controlled clinical trial. A stratified random sample of participants was allocated to one of five groups usin...

journal_title：Gerontology

authors： Wade R,Shaw K,Cartwright C

更新日期：2012-01-01 00:00:00

abstract：:A morphometric analysis of neuronal loss during normal aging was performed in the nucleus basalis Meynert complex of the basal forebrain (Nbm) (nucleus septi medialis, nucleus of Broca's diagonal band, nucleus basalis) and the ciliary ganglion, a peripheral cholinergic structure, in patients free of neurological and p...

journal_title：Gerontology

authors： Bigl V,Arendt T,Fischer S,Fischer S,Werner M,Arendt A

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Hearing impairment (HI) is a very common condition in elderly people and the epidemiology together with hearing-related problems is still poorly investigated. Moreover, the cognitive status may be impaired in relation to hearing function. OBJECTIVE:The goal of the study was to evaluate: (a) the prevalence o...

journal_title：Gerontology

authors： Cacciatore F,Napoli C,Abete P,Marciano E,Triassi M,Rengo F

更新日期：1999-11-01 00:00:00