Effect of vitamin C supplements on cell-mediated immunity in old people.

abstract：:We have previously shown that lymphocytes from Alzheimer's disease (AD) patients are hypersensitive to ionising radiation, as revealed by their higher levels of dicentrics than those from age-matched, normal individuals. We have now examined the sensitivity of these cells to N-methyl-N-nitrosourea or methyl methanesul...

journal_title：Gerontology

authors： Tobi SE,Neary D,Itzhaki RF

更新日期：1993-01-01 00:00:00

abstract：:Form birefringence curves and linear dichroic properties of aging rat tendons are different from those of adult controls. The steepness of the form birefringence curves and the increased retardations found in aging tendons are ascribed to an increase in collagen aggregation accompanied by loss of tissue water. Based o...

journal_title：Gerontology

authors： Mello ML,Vidal BC,de Carvalho AC,Caseiro-Filho AC

更新日期：1979-01-01 00:00:00

abstract：:Differences between women and men in terms of gender gaps at late stages of their lives are the focus of this mini-review. We approach the matter by taking up the position of complex yet promising standpoints, the bio-psycho-social perspective on the one hand and approaches of developmental psychology on the other. Li...

journal_title：Gerontology

authors： Kryspin-Exner I,Lamplmayr E,Felnhofer A

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Due to declining birthrates and an increasing aging population, shortage of the caregiving labor force has become a global issue. Among various efforts toward the solution, introducing robotic products for assistance could provide an effective way to help older adults in their daily lives. As previous studie...

journal_title：Gerontology

authors： Tu YC,Chien SE,Yeh SL

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Depressed mood may either precede mobility limitation or follow from mobility limitation. OBJECTIVE:To compare mood status among people with manifest mobility limitation, those with preclinical mobility limitation and those without mobility limitation and investigate factors explaining the association betwe...

journal_title：Gerontology

authors： Hirvensalo M,Sakari-Rantala R,Kallinen M,Leinonen R,Lintunen T,Rantanen T

更新日期：2007-01-01 00:00:00

abstract：:Constant exposure to new and persisting antigens and the need to replace cellular attrition with newly built cells lead to profound remodeling of the immune system after the age of 50 years. The impact of the immunosenescence process varies amongst the different cellular subsets represented within the immune system. E...

journal_title：Gerontology

authors： Jagger A,Shimojima Y,Goronzy JJ,Weyand CM

更新日期：2014-01-01 00:00:00

abstract：:For logarithmically growing cultures of the human diploid cell lines WI-38 and WI-26, there is an exponential increase in the fraction of cells not incorporating [3H]dT under conditions of continuous labelling. Thymidine uptake, phosphorylation and incorporation into DNA can be correlated with cell proliferation. In a...

journal_title：Gerontology

authors： Cristofalo VJ

更新日期：1976-01-01 00:00:00

abstract：:This paper critiques Brand and Markowitsch's viewpoint that the decision-making difficulties experienced by older adults during laboratory-based gambling tasks can be attributed to deficits in executive control and feedback operations. While Brand and Markowitsch provide an important platform with which to understand ...

journal_title：Gerontology

authors： McCarrey AC,Henry JD,Luszcz M

更新日期：2010-01-01 00:00:00

abstract：:Neuron density, volume of the area and total neuron number were measured in the medial preoptic area, supraoptic nucleus, paraventricular nucleus, anterior hypothalamic area, ventromedial nucleus, dorsomedial nucleus and arcuate nucleus of the hypothalamus in young adult male rats (3.5-5 months old) and in old male ra...

journal_title：Gerontology

authors： Peng MT,Hsü HK

更新日期：1982-01-01 00:00:00

abstract：:Anion exchange (AE) proteins are present in human neurons in the brain. Immunohistochemical data indicate that their apparent expression level increases with age, and especially with degeneration in Alzheimer's disease-affected brain areas. The increase in immunoreactivity is probably caused by changes in AE structure...

journal_title：Gerontology

authors： Bosman GJ,Renkawek K,Van Workum FP,Bartholomeus IG,De Grip WJ

更新日期：1997-01-01 00:00:00

abstract：:Aging is associated with a decline in renal concentrating ability in response to dehydration-induced arginine vasopressin (AVP) release. To examine target tissue sensitivity, cortical collecting tubules (CCT) were individually microdissected from young (3 months), middle-aged (2-3 years) and old (4-5.5 years) rabbits ...

journal_title：Gerontology

authors： Wilson PD,Dillingham MA

更新日期：1992-01-01 00:00:00

abstract：:Anaerobic bacteremia occurred in 68 patients over the age of 60 in a university hospital. These elderly patients were more likely than younger patients to have an underlying malignancy. Anaerobes involved included Bacteroides fragilis group (64 isolates), Bacteroides melaninogenicus group (11) and Clostridium species ...

journal_title：Gerontology

authors： Terpenning MS

更新日期：1989-01-01 00:00:00

abstract：:In three mouse lineages it was found that during the 18- to 60-day interval after formalin fixation, brain weight was inversely proportional to the age at sacrifice, as was the decline in the weight of the brain during this period. In a second study using rat subjects it was confirmed that the aging difference is due ...

journal_title：Gerontology

authors： Douglas RJ,Clark GM,Truncer PC,Treneer CM

更新日期：1981-01-01 00:00:00

abstract：:Phagocytically stimulated canine leukocyte suspensions obtained from 12 young adult and 43 aged individuals were examined for several physiological manifestations of the phagocytically induced respiratory burst. There was considerable variation in levels of oxygen consumption, glucose oxidation via the hexose monophos...

journal_title：Gerontology

authors： Johnson DD,Renshaw HW,Warner DH,Browder EJ,Williams JD

更新日期：1984-01-01 00:00:00

abstract：:The kinetics of cell proliferation and sister chromatid exchanges (SCE) were studied in blood lymphocytes treated by mitomycin C (MMC) in young and old human donors. In both the young and old donors MMC inhibited cell proliferation. Spontaneous SCE frequency was not age-dependent. In young donors, MMC induced a dose-r...

journal_title：Gerontology

authors： Musilová J,Michalová K,Pacovský V

更新日期：1984-01-01 00:00:00

abstract：:100 consecutive endoscopies in elderly patients referred with symptoms after previous gastric surgery are reviewed. 57% showed positive findings, and the procedure was found particularly useful in making definitive diagnoses in patients presenting with dyspepsia and upper gastro-intestinal bleeding. The incidence of g...

journal_title：Gerontology

authors： Gibbins FJ,Gupta SD,Sen I

更新日期：1985-01-01 00:00:00

abstract：:Alteration in lipid peroxidation products such as lipid peroxides, lipid hydroperoxides were studied in different regions of CNS of ageing rats (13, 26, 52, 78 and 104 weeks). The levels of lipid peroxide and lipid hydroperoxide were increased in various regions of brain and spinal cord. However, the activity of super...

journal_title：Gerontology

authors： Gupta A,Hasan M,Chander R,Kapoor NK

更新日期：1991-01-01 00:00:00

abstract：:Recently, Granacher et al. (2010) proposed an intergenerational approach to promoting balance and strength for fall prevention in children and elderly subjects together. Although this sounds like a stimulating idea, its effectiveness for fall prevention in both groups has yet to be demonstrated. Undoubtedly, fall prev...

journal_title：Gerontology

authors： Burtscher M,Kopp M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Dual-task-based assessment tests failed to establish a dependable relationship between dual-task-related gait changes and the risk of falls in the elderly. OBJECTIVE:The aim of this study was to examine whether changes in gait while counting backward could be associated with the occurrence of a first fall a...

journal_title：Gerontology

authors： Beauchet O,Allali G,Annweiler C,Berrut G,Maarouf N,Herrmann FR,Dubost V

更新日期：2008-01-01 00:00:00

abstract：:The effect of centrophenixine has been studied on the monovalent electrolyte contents of the brain cortical cells of old female Wistar rats by means of energy dispersive x-ray microanalysis. The drug was administered in form of an intraperitoneal injection of 100 mg/kg body weight for 20 days. The treatment decreased ...

journal_title：Gerontology

authors： Zs-Nagy I,Pieri C,Giuli C,Del Moro M

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Hearing impairment (HI) is a very common condition in elderly people and the epidemiology together with hearing-related problems is still poorly investigated. Moreover, the cognitive status may be impaired in relation to hearing function. OBJECTIVE:The goal of the study was to evaluate: (a) the prevalence o...

journal_title：Gerontology

authors： Cacciatore F,Napoli C,Abete P,Marciano E,Triassi M,Rengo F

更新日期：1999-11-01 00:00:00

abstract：:The life span of Drosophila melanogaster was reduced when copper compounds were fed at concentrations of 1 X 10(-3) M or greater. Feeding lower concentrations of copper compounds failed to significantly change life span. A combination of copper gluconate and gluconic acid increased the adult life span by 21.6%. We con...

journal_title：Gerontology

authors： Massie HR,Williams TR,Aiello VR

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:The common cause account suggests that there is a third factor causing aging effects in both sensory and cognitive functioning, hypothesized to be the integrity of the central nervous system [Lindenberger and Baltes; Psychol Aging 1994;9:339-355]. Importantly, the common cause account was developed based on ...

journal_title：Gerontology

authors： Sternäng O,Jonsson B,Wahlin A,Nyberg L,Nilsson LG

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Although foot pain has been linked to fall risk, contributions of pain severity, foot posture, or foot function are unclear. These factors were examined in a cohort of older adults. OBJECTIVE:The purpose of this study was to examine the associations of foot pain, severity of foot pain, and measures of foot ...

journal_title：Gerontology

authors： Awale A,Hagedorn TJ,Dufour AB,Menz HB,Casey VA,Hannan MT

更新日期：2017-01-01 00:00:00

abstract：:Walking and other physical activities were studied in a representative population sample of 619 70-year-old people in the city of Gothenburg, Sweden. Walking was the most common physical activity declared, and two thirds of those without an obvious disability walked 30 min or more every day. Subjects who took a daily ...

journal_title：Gerontology

authors： Frändin K,Grimby G,Mellström D,Svanborg A

更新日期：1991-01-01 00:00:00

abstract：INTRODUCTION:Declines in physical fitness can notably affect healthy aging of older adults. Multimodal exercise training regimen such as mind-body interventions (MBIs) has been reported to mitigate these aging-related declines of physical function. This meta-analytical review aimed at pooling the effects of MBIs on phy...

journal_title：Gerontology

authors： Ebner SA,Meikis L,Morat M,Held S,Morat T,Donath L

更新日期：2021-01-27 00:00:00

abstract：:Research into the aetiology of osteoarthritis has for several decades been concentrated on the destruction of the articular cartilage, the initiating events being believed to be changes in the proteoglycans and subsequently in the supporting collagenous framework, whereafter the disease is irreversible. Recent evidenc...

journal_title：Gerontology

authors： Bailey AJ,Mansell JP

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Old age has traditionally been considered to begin at age 65. The improving health and functional status observed among older people may necessitate reevaluation of this cut-off point. OBJECTIVE:To present the changing prevalence of common geriatric syndromes, functional parameters, common disease status an...

journal_title：Gerontology

authors： Jacobs JM,Maaravi Y,Cohen A,Bursztyn M,Ein-Mor E,Stessman J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:While many studies investigate the factors that influence the institutionalisation of older persons, only a few consider one of its most important predictors, namely, the perceived need for institutionalisation. Also referred to as 'desire for institutionalisation', it has mainly been investigated for inform...

journal_title：Gerontology

authors： Dubois MF,Dubuc N,Raîche M,Caron CD,Hébert R

更新日期：2008-01-01 00:00:00

abstract：:Demented elderly patients unable to eat independently and often refusing food are threatened by malnutrition. Therefore, we determined in 6 female patients aged 74-100 with senile dementia the average daily food consumption within a 3-week period by the exact weighing methods on six occasions. The average daily energy...

journal_title：Gerontology

authors： Stähelin HB,Hofer HO,Vogel M,Held C,Seiler WO

更新日期：1983-01-01 00:00:00