Involvement of neuronal anion exchange proteins in cell death in Alzheimer's disease.

abstract：:Fishes exhibit a 'determinate' type of growth in short-lived species of warmer regions and an 'indeterminate' type in long-lived species of colder regions. Growth is measured in units of length and weight and is best represented as the specific growth rate. The relationship between weight and length provides an index ...

journal_title：Gerontology

authors： Dutta H

更新日期：1994-01-01 00:00:00

abstract：:Induced tyrosine aminotransferase from adult and old rat liver was purified and its properties were studied. No differences could be detected for any physicochemical properties studied, i.e. specific activity, molecular weight, isoelectric point, thermostability, sensitivity to trypsin, Km for pyridoxal phosphate. Mor...

journal_title：Gerontology

authors： Szajnert MF,Schapira F

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:The aim of the present article is to discuss the potential of gene therapy for thymic hormones as a novel therapeutic strategy to treat dyshomeostatic states associated with athymia, as Di George syndrome, or hypothymic conditions like those associated with AIDS, chronic stress or aging. First ...

journal_title：Gerontology

authors： Goya RG,Cónsole G,Hereñú C,Brown O,Rimoldi OJ

更新日期：2002-09-01 00:00:00

abstract：:The specific activities of NAD-linked isocitric dehydrogenase were determined in hypothalamus, cerebellum, pons and medulla, striatum, midbrain, and cerebral cortex (which included the hippocampus) of the female Wistar rat. In ageing the specific activities of this enzyme were decreased in all regions. Chronic treatme...

journal_title：Gerontology

authors： Lai JC,Leung TK,Lim L

更新日期：1982-01-01 00:00:00

abstract：:A brief review is given of the use of fluoride, mithramycin, glucagon, actinomycin D, calcitonins and diphosphonates for treatment of Paget's disease of bone. The decision regarding treatment, effectiveness of the drugs, the incidence of side effects and assessment of clinical, biochemical, histological, radiological ...

journal_title：Gerontology

authors： Chakravorty NK

更新日期：1979-01-01 00:00:00

abstract：:A profound influence of steroidal (and possibly growth) hormone change during aging on the P-450 functions has been found in male rats. Direct and rapid autonomic nervous controls on glycogen metabolism in the liver is also greatly affected by aging. However, neither the responses of isolated rat hepatocyte preparatio...

journal_title：Gerontology

authors： Kitani K

更新日期：1988-01-01 00:00:00

abstract：:Metabolic, endocrine and biochemical variables of female hamsters were studied to define age-related alterations in their characteristics. Endurance performance, aerobic capacity and metabolic fuels and hormones were measured and compared in young-adult (2-3 months) and old (16-17 months) hamsters to determine if the ...

journal_title：Gerontology

authors： Nichols JF,Borer KT

更新日期：1987-01-01 00:00:00

abstract：:The 'use it or lose it' hypothesis of cognitive aging predicts that engagement in intellectual, social, and physical activities offers protective benefits from age-related cognitive decline and lowers dementia risk. Although this hypothesis has not yet been supported conclusively, there is some empirical evidence in f...

journal_title：Gerontology

authors： Bielak AA

更新日期：2010-01-01 00:00:00

abstract：:The effect of ageing on the threshold firing rate of motor units from the first dorsal interosseous muscle was investigated. Two groups of 9 healthy male subjects between the ages of 20-29 and 60-69 years took part in the study. The threshold firing rate of motor units in young subjects showed close agreement with pre...

journal_title：Gerontology

authors： Newton JP,Yemm R,McDonagh MJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Aging changes in different body system are well described, but few studies have considered the relationship between them. OBJECTIVE:The purpose of this study was, therefore, to investigate the interrelationships between markers of aging in different parts of the body. METHODS:A cross-sectional study design...

journal_title：Gerontology

authors： Aihie Sayer A,Osmond C,Briggs R,Cooper C

更新日期：1999-01-01 00:00:00

abstract：INTRODUCTION:The identification of modifiable health span-promoting factors is a public health priority. OBJECTIVE:To explore the socio-environmental, lifestyle, behavioural, and psychological determinants of a clinical phenotypic measure of biological ageing in the Singapore Longitudinal Ageing Study (SLAS) cohort. ...

journal_title：Gerontology

authors： Ng TP,Zhong X,Gao Q,Gwee X,Chua DQL,Larbi A

更新日期：2020-01-01 00:00:00

abstract：:Dietary intake, sunlight exposure and 25-hydroxy-vitamin D levels were estimated in 62 patients admitted to a geriatric assessment unit. There was a significant correlation between vitamin D intake and 25-hydroxy-vitamin D levels but none between sunlight exposure and these. This suggests that in old age dietary defic...

journal_title：Gerontology

authors： Nayal AS,MacLennan WJ,Hamilton JC,Rose P,Kong M

更新日期：1978-01-01 00:00:00

abstract：:Alloxan diabetes in Swiss mice of both sexes accelerated the ageing of collagen in newly formed cotton pellet granuloma concomitant with its similar effect on dorsal skin. The degree of response of collagen to alloxanization was dependent on the duration of the treatment and the sex of the animal. It is suggested that...

journal_title：Gerontology

authors： Behera HN,Patnaik BK

更新日期：1981-01-01 00:00:00

abstract：:We evaluated quantitatively the efficiency and safety of, and influence of either prior arterial injury or immunity against adenovirus on adenovirus-mediated gene transfer into injured arteries of a relatively large animal model, the dog. A replication-defective adenovirus expressing bacterial lacZ was introduced perc...

journal_title：Gerontology

authors： Ueno H

更新日期：1996-01-01 00:00:00

abstract：:Differences between women and men in terms of gender gaps at late stages of their lives are the focus of this mini-review. We approach the matter by taking up the position of complex yet promising standpoints, the bio-psycho-social perspective on the one hand and approaches of developmental psychology on the other. Li...

journal_title：Gerontology

authors： Kryspin-Exner I,Lamplmayr E,Felnhofer A

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Previous studies have shown links between cognitive impairment and hypertension as well as mortality. However, combined effects of these two conditions on mortality have not been fully explored. OBJECTIVE:To assess the combined effect of cognitive impairment and hypertension on all-cause mortality among the...

journal_title：Gerontology

authors： Gombojav B,Yi SW,Sull JW,Nam CM,Ohrr H

更新日期：2011-01-01 00:00:00

abstract：:As populations age globally, the health of older adults is looming larger on the agendas of public health bodies. In particular, the priority is to ensure that older adults remain healthy, independent, and engaged in their communities. In other words, ensuring that increasing life spans are matched by increasing "heal...

journal_title：Gerontology

authors： Doherty TM,Di Pasquale A,Michel JP,Del Giudice G

更新日期：2020-01-01 00:00:00

abstract：UNLABELLED:BACKGROUND; The link between experiencing difficulties in reading or understanding and non-compliance with drug treatment among seniors is not clearly established. OBJECTIVES:We measured the effect of both difficulties in reading, as well as difficulties in understanding prescription labelling, on non-compl...

journal_title：Gerontology

authors： Moisan J,Gaudet M,Grégoire JP,Bouchard R

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Although a relationship between diet and mortality is well recognized, there is little information on the extent to which different food sources contribute to survival in elderly people. OBJECTIVE:To examine the effect of individual food groups on mortality in institutionalized elderly people from Asturias ...

journal_title：Gerontology

authors： González S,Huerta JM,Fernández S,Patterson AM,Lasheras C

更新日期：2008-01-01 00:00:00

abstract：:Protein malnutrition is associated with a decreased febrile and acute phase response to infection and increased mortality. To elucidate a cause for this poor response, we assessed the effect of chronic protein malnutrition on monocyte production of the pyrogens interleukin-1 (IL-1) and tumor necrosis factor (TNF). Thi...

journal_title：Gerontology

authors： Bradley SF,Vibhagool A,Fabrick S,Terpenning MS,Kauffman CA

更新日期：1990-01-01 00:00:00

abstract：:The characteristics of long-stay patients (defined as those staying more than 6 months) have been studied in a prospective series of 2,405 admissions. 5.6% become long-stay patients and they were more likely to be women, to be readmissions, to have been admitted from an old people's home, to have been non-emergency ad...

journal_title：Gerontology

authors： Hodkinson I,Hodkinson HM

更新日期：1981-01-01 00:00:00

abstract：:Alzheimer neurofibrillary changes and senile plaques were found in a variety of distribution patterns and intensities in 50 brains of patients older than 73 years who had been carefully examined for signs of organic dementia in a geriatric unit. As noted by earlier observers, the severity of dementia usually correspon...

journal_title：Gerontology

authors： Ulrich J,Stähelin HB

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVES:Due to an increase in the percentage of older people in industrialized countries there is an increasing demand for medical care for the elderly. With advancing age, a series of structural, architectural and compositional modifications take place in the vasculature. Therefore, we analyzed the influence of pat...

journal_title：Gerontology

authors： Kröger K,Strubel G,Poser M,Pratikto T,Renzing-Köhler K,Rudofsky G

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Wheelchairs are frequently prescribed for residents with mobility impairments in long-term care. Many residents receive poorly fitting wheelchairs, compromising functional independence and mobility, and contributing to subsequent health issues such as pressure ulcers. The extent of this problem and the facto...

journal_title：Gerontology

authors： Giesbrecht EM,Mortenson WB,Miller WC

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Mortality in the intensive care unit (ICU) rises with age, a high basal serum cortisol and a small response to adrenocorticotropin (ACTH) stimulation. Even slight impairment of the adrenal response during severe illness can be lethal. OBJECTIVES:To determine if age is associated with changes in basal or sti...

journal_title：Gerontology

authors： Beale E,Zhu J,Belzberg H

更新日期：2002-03-01 00:00:00

abstract：:The spectrum of aldimine cross-link bonds of skin collagen is dependent on the localization of the examined material. In correlation to this, there is no synchronous behaviour of cross-linkage in the aging process. The age-dependent decrease of HLNL and the increase of DHLNL in the collagen of tail tendon is only unsu...

journal_title：Gerontology

authors： Ruiz-Torres A

更新日期：1978-01-01 00:00:00

abstract：:We performed 24-hour ambulatory electrocardiographic (Holter) examinations in 50 retired hospital workers (30 men, 20 women), aged 58-85 years (mean age +/- SD: 65.9 +/- 4.6 years), with a normal clinical history, physical examination and baseline ECG. There was a significant difference between daytime and nocturnal m...

journal_title：Gerontology

authors： Ribera JM,Cruz AJ,Zamorano JL,Pérez-Casar F

更新日期：1989-01-01 00:00:00

abstract：:Recently, Granacher et al. (2010) proposed an intergenerational approach to promoting balance and strength for fall prevention in children and elderly subjects together. Although this sounds like a stimulating idea, its effectiveness for fall prevention in both groups has yet to be demonstrated. Undoubtedly, fall prev...

journal_title：Gerontology

authors： Burtscher M,Kopp M

更新日期：2011-01-01 00:00:00

abstract：:The Zika virus (ZIKV) outbreak in French Polynesia, in 2013, and in Brazil, in 2015, was correlated with neurological complications, which comprised, among others, congenital microcephaly and Guillain-Barré syndrome (GBS), which includes a group of acute autoimmune neuropathies generally reported after respiratory or ...

journal_title：Gerontology

authors： Savino W,Messias CV,Mendes-da-Cruz DA,Passos P,Ferreira AC,Nascimento OJ

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Mild-to-moderate chronic kidney disease (CKD G3a) is prevalent in older adults. Substantial evidence suggests that individuals with advanced CKD face a high risk for common geriatric conditions, like functional impairment and cognitive decline, whereas the relationships between mild-to-moderate CKD and funct...

journal_title：Gerontology

authors： König M,Gollasch M,Spira D,Buchmann N,Hopfenmüller W,Steinhagen-Thiessen E,Demuth I

更新日期：2018-01-01 00:00:00