Effect of alloxan diabetes on the characteristics of collagen of cotton pellet granuloma and dorsal skin of Swiss mice.

Abstract:

:Alloxan diabetes in Swiss mice of both sexes accelerated the ageing of collagen in newly formed cotton pellet granuloma concomitant with its similar effect on dorsal skin. The degree of response of collagen to alloxanization was dependent on the duration of the treatment and the sex of the animal. It is suggested that the physiologically altered state resulting from alloxanization leads to the formation of metabolites that act as promotants of collagen cross-linking in both existing and newly formed connective tissues.

journal_name

Gerontology

journal_title

Gerontology

authors

Behera HN,Patnaik BK

doi

10.1159/000212475

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

209-15

issue

4

eissn

0304-324X

issn

1423-0003

journal_volume

27

pub_type

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