Abstract:
:Alloxan diabetes in Swiss mice of both sexes accelerated the ageing of collagen in newly formed cotton pellet granuloma concomitant with its similar effect on dorsal skin. The degree of response of collagen to alloxanization was dependent on the duration of the treatment and the sex of the animal. It is suggested that the physiologically altered state resulting from alloxanization leads to the formation of metabolites that act as promotants of collagen cross-linking in both existing and newly formed connective tissues.
journal_name
Gerontologyjournal_title
Gerontologyauthors
Behera HN,Patnaik BKdoi
10.1159/000212475subject
Has Abstractpub_date
1981-01-01 00:00:00pages
209-15issue
4eissn
0304-324Xissn
1423-0003journal_volume
27pub_type
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