Proinflammation of aging central arteries: a mini-review.

abstract：BACKGROUND:The chronic stress of providing care for a spouse suffering from Alzheimer's disease has been associated with an increased risk for coronary artery disease and overall mortality. Procoagulant changes are kindled by mental stress, and they are prospectively associated with atherothrombotic events. OBJECTIVE:...

journal_title：Gerontology

authors： von Kanel R,Dimsdale JE,Adler KA,Patterson TL,Mills PJ,Grant I

更新日期：2005-01-01 00:00:00

abstract：:Taurine (TAU) is thought to be a neuromodulator or an inhibitory neurotransmitter in the mammalian brain. In the periphery, TAU is involved in a wide spectrum of physiological functions. One of the most important putative physiological function of TAU is the modulation of cardiovascular activity including blood pressu...

journal_title：Gerontology

authors： Wallace DR,Dawson R Jr

更新日期：1990-01-01 00:00:00

abstract：:A morphometric analysis of neuronal loss during normal aging was performed in the nucleus basalis Meynert complex of the basal forebrain (Nbm) (nucleus septi medialis, nucleus of Broca's diagonal band, nucleus basalis) and the ciliary ganglion, a peripheral cholinergic structure, in patients free of neurological and p...

journal_title：Gerontology

authors： Bigl V,Arendt T,Fischer S,Fischer S,Werner M,Arendt A

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Orthostatic hypotension (OH) is common in older adults and associated with increased morbidity and mortality, loss of independence and high health-care costs. Standing up slowly is a recommended non-pharmacological intervention. However, the effectiveness of this advice has not been well studied. OBJECTIVES...

journal_title：Gerontology

authors： de Bruïne ES,Reijnierse EM,Trappenburg MC,Pasma JH,de Vries OJ,Meskers CG,Maier AB

更新日期：2017-01-01 00:00:00

abstract：:Glutamine synthetase (GS) activity was measured in whole brain, different brain areas, liver and heart of 23- to 26-month-old rats, and then compared to matched animals of 3 months. A significant increase of GS activity was found in whole brain (25%) of old rats, as well as in all brain areas studied, but particularly...

journal_title：Gerontology

authors： Cao Danh H,Strolin Benedetti M,Dostert P

更新日期：1985-01-01 00:00:00

abstract：:The life span of Drosophila melanogaster was reduced when copper compounds were fed at concentrations of 1 X 10(-3) M or greater. Feeding lower concentrations of copper compounds failed to significantly change life span. A combination of copper gluconate and gluconic acid increased the adult life span by 21.6%. We con...

journal_title：Gerontology

authors： Massie HR,Williams TR,Aiello VR

更新日期：1984-01-01 00:00:00

abstract：:The Hermansky-Pudlak syndrome (HPS) is an autosomal recessive disease characterized by a triad of oculocutaneous albinism, accumulation of auto-fluorescent ceroid-like pigments within macrophages, and bleeding tendency due to a storage pool disease of the platelets. We report an autopsy case (39y, male), who died of p...

journal_title：Gerontology

authors： Ohbayashi C,Kanomata N,Imai Y,Ito H,Shimasaki H

更新日期：1995-01-01 00:00:00

abstract：:Paraneoplastic symptoms, caused by a malignancy, but not directly related to invasion by the tumor or its metastases, are the result of a wide variety of tumor-derived biologic mediators like hormones, peptides, antibodies, cytotoxic lymphocytes, autocrine and paracrine mediators. Systemic inflammatory rheumatic disea...

journal_title：Gerontology

authors： Szekanecz Z,Szekanecz E,Bakó G,Shoenfeld Y

更新日期：2011-01-01 00:00:00

abstract：:In three mouse lineages it was found that during the 18- to 60-day interval after formalin fixation, brain weight was inversely proportional to the age at sacrifice, as was the decline in the weight of the brain during this period. In a second study using rat subjects it was confirmed that the aging difference is due ...

journal_title：Gerontology

authors： Douglas RJ,Clark GM,Truncer PC,Treneer CM

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Dual-task-based assessment tests failed to establish a dependable relationship between dual-task-related gait changes and the risk of falls in the elderly. OBJECTIVE:The aim of this study was to examine whether changes in gait while counting backward could be associated with the occurrence of a first fall a...

journal_title：Gerontology

authors： Beauchet O,Allali G,Annweiler C,Berrut G,Maarouf N,Herrmann FR,Dubost V

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The chronological age is clearly the strongest risk factor for fractures or death. Age as a concept can be described exactly as chronological age. Age in relative terms can be described as biological age. OBJECTIVE:We postulated that, even without taking into account known or unknown comorbidity, an immedia...

journal_title：Gerontology

authors： Gerdhem P,Ringsberg K,Akesson K,Obrant KJ

更新日期：2004-09-01 00:00:00

abstract：:We quantitated the skin elastic fibers of the papillary and reticular dermis using specific staining procedure followed by automated computerized image analysis. Fifty skin biopsies of patients consulting for cardiovascular risk factors were studied. The following parameters were estimated: surface area (% of total su...

journal_title：Gerontology

authors： Robert C,Lesty C,Robert AM

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:The aim of the present article is to discuss the potential of gene therapy for thymic hormones as a novel therapeutic strategy to treat dyshomeostatic states associated with athymia, as Di George syndrome, or hypothymic conditions like those associated with AIDS, chronic stress or aging. First ...

journal_title：Gerontology

authors： Goya RG,Cónsole G,Hereñú C,Brown O,Rimoldi OJ

更新日期：2002-09-01 00:00:00

abstract：:Age-related changes of muscle fiber and collagen content of the diaphragm (DIA) and rectus abdominis (RA) muscles were examined in rats aged 1, 4, 8 and 18 months. The cross-sectional areas of all muscle fiber types (I, IIa, IIb) and the amount of collagen in both DIA and RA increased up to the age of 8 months after w...

journal_title：Gerontology

authors： Rodrigues CJ,Rodrigues Júnior AJ,Bohm GM

更新日期：1996-01-01 00:00:00

abstract：:The hippocampus is a structure equipped with a high degree of flexibility and adaptation. In contrast to most structures of the adult central nervous system, the hippocampus can rely on a form of plasticity known as neurogenesis. The continuous provision of new neurons derived from resident adult neural stem cells app...

journal_title：Gerontology

authors： Couillard-Despres S,Iglseder B,Aigner L

更新日期：2011-01-01 00:00:00

abstract：:Over the past decades, information about the characteristics of attractiveness has accumulated. We know about eight pillars of beauty, among them youthfulness, symmetry, hormone markers and body odor. But what is the biological function of these attractive signals? Is there one common function to be found in all eight...

journal_title：Gerontology

authors： Oberzaucher E,Grammer K

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Even though poor lighting at nighttime is an important risk factor for falls (and most falls occur during the night), lighting interventions to improve nightly lighting from bed to bathroom are rarely evaluated for fall prevention. OBJECTIVE:We tested the hypothesis that an automated guiding light would red...

journal_title：Gerontology

authors： Thölking TW,Lamers ECT,Olde Rikkert MGM

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Future time perspective has been associated with subjective well-being, though depending on the line of research considered either an open-ended future time perspective or a limited future time perspective has been associated with high well-being. Most of this research however has conceptualized future time ...

journal_title：Gerontology

authors： Kozik P,Hoppmann CA,Gerstorf D

更新日期：2015-01-01 00:00:00

abstract：:The characteristics of long-stay patients (defined as those staying more than 6 months) have been studied in a prospective series of 2,405 admissions. 5.6% become long-stay patients and they were more likely to be women, to be readmissions, to have been admitted from an old people's home, to have been non-emergency ad...

journal_title：Gerontology

authors： Hodkinson I,Hodkinson HM

更新日期：1981-01-01 00:00:00

abstract：:Lymphopenia is a common finding in old people admitted to medical and psychiatric wards. We describe a pilot study of the clinical associations, and prognostic significance of lymphopenia in elderly persons admitted to acute medical and psychiatric wards. Consecutive patients admitted to acute medical and psychiatric ...

journal_title：Gerontology

authors： Dennis MS,Nicolson A,Lehmann AB,Junaid O,Byrne EJ,Hopkinson N

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Depressed mood may either precede mobility limitation or follow from mobility limitation. OBJECTIVE:To compare mood status among people with manifest mobility limitation, those with preclinical mobility limitation and those without mobility limitation and investigate factors explaining the association betwe...

journal_title：Gerontology

authors： Hirvensalo M,Sakari-Rantala R,Kallinen M,Leinonen R,Lintunen T,Rantanen T

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:A quantitative study of dermal and arterial elastic fibers as a function of age was carried out by computerized image analysis. OBJECTIVE:We investigated whether any parallelism can be established between the morphometric parameters of elastic fibers from the skin and the temporal artery in elderly subjects...

journal_title：Gerontology

authors： Gogly B,Godeau G,Septier D,Hornebeck W,Pellat B,Jeandel C

更新日期：1998-01-01 00:00:00

abstract：:During the past decade, controversy has raged about the necessity of renal biopsy for the management of the idiopathic nephrotic syndrome. The debate has centered on whether a precise diagnosis is imperative for steroid treatment or whether such therapy can be given blindly. The above question has not been addressed i...

journal_title：Gerontology

authors： Moran D,Korzets Z,Bernheim J,Bernheim J,Yaretzky A

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:Each year, influenza and its complications account for 10,000-40,000 excess deaths in the United States. Over 80% of these deaths occur among the elderly. The Advisory Committee on Immunization Practices for the US Public Health Service and others recommend that all persons 65 years of age and older as well a...

journal_title：Gerontology

authors： Nichol KL,Margolis KL,Wouremna J,von Sternberg T

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Disturbance of vertical eye movement and ocular convergence is often observed in elderly people, but little is known about its frequency. OBJECTIVE:The purpose of this study was to investigate age-associated changes in vertical eye movement and convergence in healthy elderly people, using a digital video ca...

journal_title：Gerontology

authors： Oguro H,Okada K,Suyama N,Yamashita K,Yamaguchi S,Kobayashi S

更新日期：2004-05-01 00:00:00

abstract：:To determine the influence of age, disease and other factors on anthropometric indices in elderly subjects aged 70 years and above, body mass index (BMI), arm muscle circumference (AMC), corrected arm muscle area (CAMA), fat-free mass (FFM) and total body fat (TBF) were determined in a random sample of 990 Chinese men...

journal_title：Gerontology

authors： Woo J,Ho SC,Sham A,Yuen YK,Chan SG

更新日期：1995-01-01 00:00:00

abstract：:Prospective surveillance of nosocomial infection was conducted at seven skilled proprietary nursing facilities in Orange County, Calif., USA. The average incidence of facility-acquired infection was 5.2 infections/1,000 patient days. The most common source of infection was urinary tract (47%), followed by respiratory ...

journal_title：Gerontology

authors： Lee YL,Thrupp LD,Friis RH,Fine M,Maleki P,Cesario TC

更新日期：1992-01-01 00:00:00

abstract：:Constant exposure to new and persisting antigens and the need to replace cellular attrition with newly built cells lead to profound remodeling of the immune system after the age of 50 years. The impact of the immunosenescence process varies amongst the different cellular subsets represented within the immune system. E...

journal_title：Gerontology

authors： Jagger A,Shimojima Y,Goronzy JJ,Weyand CM

更新日期：2014-01-01 00:00:00

abstract：:Although the two-point discrimination test of the skin is a simple test of the sensory nerve function, there have been few studies on age-related changes in the ability to discriminate between two points in a large noninstitutionalized population. In this study we attempted (1) to determine normal values on the two-po...

journal_title：Gerontology

authors： Shimokata H,Kuzuya F

更新日期：1995-01-01 00:00:00

abstract：:The prevalence of and risk factors for varicose veins (VV) were studied in elderly persons over 60 years of age who had visited the Tonya and Farabi Hospitals in Trabzon, a city in northeastern Turkey. VV were defined as dilated, tortuous and elongated veins of the lower extremities and were classified into four types...

journal_title：Gerontology

authors： Komsuoğlu B,Göldeli O,Kulan K,Cetinarslan B,Komsuoğlu SS

更新日期：1994-01-01 00:00:00