Activities of the mitochondrial NAD-linked isocitric dehydrogenase in different regions of the rat brain: changes in ageing and the effect of chronic manganese chloride administration.

abstract：:We studied the correlation between the in vitro lymphocyte proliferative response and some early parameters of lymphocyte activation in aged people. While a consistent number of elderly subjects showed significantly decreased proliferative responses to mitogen stimulation, interleukin-1 (IL-1) production and IL-2 rece...

journal_title：Gerontology

authors： Amadori A,Zanovello P,Cozzi E,Ciminale V,Borghesan F,Fagiolo U,Crepaldi G

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Studies have demonstrated that measures of lower quality of care and associated adverse health effects are more prevalent in for-profit nursing homes compared to not-for-profit facilities. However, these studies omit persons who receive care in the community setting, and exclusively focus on isolated clinica...

journal_title：Gerontology

authors： Friedman L,Avila S,Friedman D,Meltzer W

更新日期：2019-01-01 00:00:00

abstract：:The effect of centrophenixine has been studied on the monovalent electrolyte contents of the brain cortical cells of old female Wistar rats by means of energy dispersive x-ray microanalysis. The drug was administered in form of an intraperitoneal injection of 100 mg/kg body weight for 20 days. The treatment decreased ...

journal_title：Gerontology

authors： Zs-Nagy I,Pieri C,Giuli C,Del Moro M

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:To focus on diagnostic and therapeutic problems of pulmonary embolism in the elderly. METHODS:Retrospective analysis of 5 years of clinical, instrumental, and laboratory data (collected at the time of hospital admission) for patients 65 years and older with pulmonary embolism proven by a high-probability sci...

journal_title：Gerontology

authors： Masotti L,Ceccarelli E,Cappelli R,Guerrini M,Forconi S

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:The chronological age is clearly the strongest risk factor for fractures or death. Age as a concept can be described exactly as chronological age. Age in relative terms can be described as biological age. OBJECTIVE:We postulated that, even without taking into account known or unknown comorbidity, an immedia...

journal_title：Gerontology

authors： Gerdhem P,Ringsberg K,Akesson K,Obrant KJ

更新日期：2004-09-01 00:00:00

abstract：INTRODUCTION:Many falls in older adults occur during walking and result in lateral falls. The ability to perform a recovery step after balance perturbation determines whether a fall will occur. AIM:To investigate age-related changes in first recovery step kinematics and kinematic adaptations over a wide range of later...

journal_title：Gerontology

authors： Nachmani H,Shani G,Shapiro A,Melzer I

更新日期：2020-01-01 00:00:00

abstract：:The subcellular distribution of estradiol following the in vivo administration of 3H-estradiol, cytosol and nuclear estrogen receptor after in vitro incubation with 3H-estradiol were studied in young adult female rats (3-6 months old) and old female rats (over 18 months old). After intravenous injection of 3H-estradio...

journal_title：Gerontology

authors： Jiang MJ,Peng MT

更新日期：1981-01-01 00:00:00

abstract：:A morphometric analysis of neuronal loss during normal aging was performed in the nucleus basalis Meynert complex of the basal forebrain (Nbm) (nucleus septi medialis, nucleus of Broca's diagonal band, nucleus basalis) and the ciliary ganglion, a peripheral cholinergic structure, in patients free of neurological and p...

journal_title：Gerontology

authors： Bigl V,Arendt T,Fischer S,Fischer S,Werner M,Arendt A

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:C-reactive protein (CRP), a nonspecific marker of the inflammatory status, is associated with cardiovascular disease risk factors and may be an important feature of the metabolic syndrome (MSX) in middle-aged subjects. OBJECTIVES:We assessed the relationship of CRP levels to specific components of MSX and o...

journal_title：Gerontology

authors： Dupuy AM,Jaussent I,Lacroux A,Durant R,Cristol JP,Delcourt C

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:The identification of modifiable health span-promoting factors is a public health priority. OBJECTIVE:To explore the socio-environmental, lifestyle, behavioural, and psychological determinants of a clinical phenotypic measure of biological ageing in the Singapore Longitudinal Ageing Study (SLAS) cohort. ...

journal_title：Gerontology

authors： Ng TP,Zhong X,Gao Q,Gwee X,Chua DQL,Larbi A

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:It has been proposed that active engagement with life may protect against cognitive decline. However, existing instruments for measuring life engagement have covered limited domains. OBJECTIVE:To present a new instrument to measure engagement with life; the RIASEC Activities List draws on activities categor...

journal_title：Gerontology

authors： Parslow RA,Jorm AF,Christensen H,Mackinnon A

更新日期：2006-01-01 00:00:00

abstract：:Differences between women and men in terms of gender gaps at late stages of their lives are the focus of this mini-review. We approach the matter by taking up the position of complex yet promising standpoints, the bio-psycho-social perspective on the one hand and approaches of developmental psychology on the other. Li...

journal_title：Gerontology

authors： Kryspin-Exner I,Lamplmayr E,Felnhofer A

更新日期：2011-01-01 00:00:00

abstract：:Older adults often face challenges as they transition out of the acute care hospital, especially with regard to adhering to their medications. In this narrative review, we discuss medication adherence in older adults across the continuum of care, describing reasons for nonadherence, methods to assess adherence and too...

journal_title：Gerontology

authors： Mixon AS,Neal E,Bell S,Powers JS,Kripalani S

更新日期：2015-01-01 00:00:00

abstract：:Hyposplenism has been reported in elderly people. However, from previous studies, it was not clear whether the observed alterations in splenic function were a physiologic effect of advanced age itself or a consequence of age-related diseases. As hyposplenism is believed to predispose to infections, autoimmune phenomen...

journal_title：Gerontology

authors： Ravaglia G,Forti P,Biagi F,Maioli F,Boschi F,Corazza GR

更新日期：1998-01-01 00:00:00

abstract：:The purpose of this study was to examine the effects of a multifactorial memory training program designed for normal older adults. The multifactorial program involved the training of three components that are critical to memory functioning: recoding operations, attentional functions and relaxation. Two controls groups...

journal_title：Gerontology

authors： Stigsdotter A,Bäckman L

更新日期：1989-01-01 00:00:00

abstract：:Dietary intake, sunlight exposure and 25-hydroxy-vitamin D levels were estimated in 62 patients admitted to a geriatric assessment unit. There was a significant correlation between vitamin D intake and 25-hydroxy-vitamin D levels but none between sunlight exposure and these. This suggests that in old age dietary defic...

journal_title：Gerontology

authors： Nayal AS,MacLennan WJ,Hamilton JC,Rose P,Kong M

更新日期：1978-01-01 00:00:00

abstract：:The experimental evidence is reviewed which bears on the theory that aging in mammalian cells may be related to a decline in the efficiency of normal DNA repair processes. Although the data are as yet fragmentary, they do suggest that there is an age-associated decline in the capacity of cells to perform at least cert...

journal_title：Gerontology

authors： Little JB

更新日期：1976-01-01 00:00:00

abstract：:The prevalence of and risk factors for varicose veins (VV) were studied in elderly persons over 60 years of age who had visited the Tonya and Farabi Hospitals in Trabzon, a city in northeastern Turkey. VV were defined as dilated, tortuous and elongated veins of the lower extremities and were classified into four types...

journal_title：Gerontology

authors： Komsuoğlu B,Göldeli O,Kulan K,Cetinarslan B,Komsuoğlu SS

更新日期：1994-01-01 00:00:00

abstract：:Sarcopenia is a complex and multifactorial disease that includes a decrease in the number, structure and physiology of muscle fibers, and age-related muscle mass loss, and is associated with loss of strength, increased frailty, and increased risk for fractures and falls. Treatment options are suboptimal and consist of...

journal_title：Gerontology

authors： Naranjo JD,Dziki JL,Badylak SF

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To examine the relationships between upper extremity function (UEF) and mortality, need for social assistance and change of residence, at discharge from hospital and at 1 month following discharge. METHODS:Observational, cohort study. SETTING:Acute Geriatric Unit of a Tertiary Teaching Hospital. SUBJECTS:3...

journal_title：Gerontology

authors： Abizanda P,Navarro JL,Romero L,León M,Sánchez-Jurado PM,Domínguez L

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Malnutrition is a widespread but largely unrecognized problem in aged patients, more so as it is a contributing factor to the increased morbidity and mortality in this age group. Since direct measurements of body composition are not possible in a large number of patients, good anthropometric reference data a...

journal_title：Gerontology

authors： Bonnefoy M,Jauffret M,Kostka T,Jusot JF

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Previous studies have shown links between cognitive impairment and hypertension as well as mortality. However, combined effects of these two conditions on mortality have not been fully explored. OBJECTIVE:To assess the combined effect of cognitive impairment and hypertension on all-cause mortality among the...

journal_title：Gerontology

authors： Gombojav B,Yi SW,Sull JW,Nam CM,Ohrr H

更新日期：2011-01-01 00:00:00

abstract：:Recently, Granacher et al. (2010) proposed an intergenerational approach to promoting balance and strength for fall prevention in children and elderly subjects together. Although this sounds like a stimulating idea, its effectiveness for fall prevention in both groups has yet to be demonstrated. Undoubtedly, fall prev...

journal_title：Gerontology

authors： Burtscher M,Kopp M

更新日期：2011-01-01 00:00:00

abstract：:Hydrogen breath testing (HBT) is frequently used as an alternative to small bowel aspiration in the diagnosis of small intestinal bacterial overgrowth (SIBO). The role of the glucose HBT was assessed in 30 elderly patients. A positive HBT was recorded in 15 of 20 SIBO cases and 7 of 10 culture negatives (sensitivity 7...

journal_title：Gerontology

authors： Mac Mahon M,Gibbons N,Mullins E,O'Moore RR,Keane CT,Walsh JB,Coakley D

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Perceived stress may be a modifiable risk factor for mild cognitive impairment (MCI) and ultimately dementia, but studies on this topic from low- and middle-income countries (LMICs) are lacking. OBJECTIVE:We assessed the association between perceived stress and MCI in six LMICs (China, Ghana, India, Mexico,...

journal_title：Gerontology

authors： Koyanagi A,Oh H,Vancampfort D,Carvalho AF,Veronese N,Stubbs B,Lara E

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Creutzfeldt-Jakob disease (CJD) is not only a disorder of the central nervous system but also affects the skeletal muscle. Subclinical skeletal muscle involvement, manifesting as hyper-creatine-kinase (CK)-emia, is rare. CASE REPORT:The patient, a 60-year-old male, developed progressive dementia, accompanie...

journal_title：Gerontology

authors： Finsterer J,Gelpi E

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Relationships between alcohol consumption and risks for metabolic syndrome in general populations are very controversial. It is unknown whether age influences the relationship between alcohol intake and the prevalence of metabolic syndrome. OBJECTIVE:The purpose of this study was to determine whether age in...

journal_title：Gerontology

authors： Wakabayashi I

更新日期：2012-01-01 00:00:00

abstract：:A brief review is given of the use of fluoride, mithramycin, glucagon, actinomycin D, calcitonins and diphosphonates for treatment of Paget's disease of bone. The decision regarding treatment, effectiveness of the drugs, the incidence of side effects and assessment of clinical, biochemical, histological, radiological ...

journal_title：Gerontology

authors： Chakravorty NK

更新日期：1979-01-01 00:00:00

abstract：:Arterial aging is a cornerstone of organismal aging. The central arterial wall structurally and functionally remodels under chronic proinflammatory stress over a lifetime. The low-grade proinflammation that accompanies advancing age causes arterial wall thickening and stiffening. These structural and functional altera...

journal_title：Gerontology

authors： Wang M,Monticone RE,Lakatta EG

更新日期：2014-01-01 00:00:00

abstract：:We use nerve tissue cultures as a model system for studying the mode of action of centrally acting drugs. Neurons in cerebellar cultures retain a number of organ-specific properties including the formation of complex synaptic networks and characteristic bioelectric activity. Electrical activity may be recorded from Pu...

journal_title：Gerontology

authors： Gähwiler BH

更新日期：1978-01-01 00:00:00