Abstract:
BACKGROUND:Malnutrition is a widespread but largely unrecognized problem in aged patients, more so as it is a contributing factor to the increased morbidity and mortality in this age group. Since direct measurements of body composition are not possible in a large number of patients, good anthropometric reference data are fundamental in assessing the nutritional state of elderly people. OBJECTIVE:To examine the efficacy of calf circumference (CC) measurement for assessing the nutritional state of the elderly. METHODS:The nutritional state was assessed by anthropometric and biological measurements in 911 elderly patients consecutively admitted to a geriatric unit. In the first instance, univariate analysis was performed for CC and other nutritional parameters. Linear and multiple stepwise regressions were performed to study the association between anthropometric or biological parameters and CC. At a later stage, the specificity, sensitivity and the optimal cutoff CC were established for 2 groups of patients: malnourished and controls. Finally, patients were classified according to this cutoff in order to verify the efficacy of CC in assessing their nutritional state. RESULTS:The results of univariate analysis showed significant correlations between CC and other nutritional anthropometric markers (r = 0.706, p < 0.0001 with body mass index (BMI) and r = 0.661, p < 0.0001 with fat free mass) and biological markers (r = 0.219, p < 0.0001 with albumin and r = 0.162, p < 0.0001 with transthyretin). Multiple regression confirmed associations between CC and tricipital skinfold thickness (p < 0.0001), fat free mass (p < 0.0001), BMI (p < 0.0001), and serum albumin (p < 0.0001; r(2) = 0.561). The optimal cutoff for CC was found to be 30.5 cm for both men (sensitivity 73.2%, specificity 72.8%) and women (sensitivity 78.8%, specificity 61.1%). The classification of patients according to this discriminating factor was confirmed for the optimal cutoff value. CONCLUSION:Calf circumference is a pertinent marker of nutritional state. The cutoff of 30.5 cm provides a good diagnostic capacity.
journal_name
Gerontologyjournal_title
Gerontologyauthors
Bonnefoy M,Jauffret M,Kostka T,Jusot JFdoi
10.1159/000052836keywords:
subject
Has Abstractpub_date
2002-05-01 00:00:00pages
162-9issue
3eissn
0304-324Xissn
1423-0003pii
52836journal_volume
48pub_type
杂志文章相关文献
GERONTOLOGY文献大全abstract::Alloxan diabetes in Swiss mice of both sexes accelerated the ageing of collagen in newly formed cotton pellet granuloma concomitant with its similar effect on dorsal skin. The degree of response of collagen to alloxanization was dependent on the duration of the treatment and the sex of the animal. It is suggested that...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212475
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Even though poor lighting at nighttime is an important risk factor for falls (and most falls occur during the night), lighting interventions to improve nightly lighting from bed to bathroom are rarely evaluated for fall prevention. OBJECTIVE:We tested the hypothesis that an automated guiding light would red...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000504883
更新日期:2020-01-01 00:00:00
abstract::To evaluate the requirement for provocative cystometry in urodynamic investigation in the elderly with urinary incontinence, 100 consecutive patients, who were referred on the basis of defined clinical criteria, were first studied by supine cystometry followed by provocative tests where necessary. The most satisfactor...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212791
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:In Germany, there is an ongoing concern about the high prevalence of underweight on admission to health-care institutions. In order to assess possible sex-specific differences, the aim of this study is to provide valid figures about the prevalence and risk factors of underweight of men and women in German nur...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000512459
更新日期:2021-01-20 00:00:00
abstract::Dietary intake, sunlight exposure and 25-hydroxy-vitamin D levels were estimated in 62 patients admitted to a geriatric assessment unit. There was a significant correlation between vitamin D intake and 25-hydroxy-vitamin D levels but none between sunlight exposure and these. This suggests that in old age dietary defic...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212244
更新日期:1978-01-01 00:00:00
abstract::The interactions of ergot alkaloids and of other drugs with dopamine (DA) and alpha-adrenergic receptors were investigated. The tested ergot alkaloids inhibit synaptosomal tyrosine hydroxylase activity and reverse the apomorphine-elicited inhibition of synaptosomal tyrosine hydroxylase activity. Thus, ergot alkaloids ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212301
更新日期:1978-01-01 00:00:00
abstract::The experimental evidence is reviewed which bears on the theory that aging in mammalian cells may be related to a decline in the efficiency of normal DNA repair processes. Although the data are as yet fragmentary, they do suggest that there is an age-associated decline in the capacity of cells to perform at least cert...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000212123
更新日期:1976-01-01 00:00:00
abstract::The subcellular distribution of estradiol following the in vivo administration of 3H-estradiol, cytosol and nuclear estrogen receptor after in vitro incubation with 3H-estradiol were studied in young adult female rats (3-6 months old) and old female rats (over 18 months old). After intravenous injection of 3H-estradio...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212449
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Myostatin has been proposed as a candidate biomarker for frailty and sarcopenia. However, the relationship of myostatin with these conditions remains inconclusive. OBJECTIVE:To determine the association of serum myostatin concentration with body composition, physical fitness, physical activity level, and fr...
journal_title:Gerontology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000494137
更新日期:2019-01-01 00:00:00
abstract::Demented elderly patients unable to eat independently and often refusing food are threatened by malnutrition. Therefore, we determined in 6 female patients aged 74-100 with senile dementia the average daily food consumption within a 3-week period by the exact weighing methods on six occasions. The average daily energy...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213107
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:The leading causes of death and disability in the elderly are from cardiovascular and cerebrovascular diseases. The biological role of stem cells in the hematopoietic system has been well characterized and has led to the development of hematopoietic stem and progenitor cell (HSPC) transplantation for the tre...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000156223
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To examine the relationships between upper extremity function (UEF) and mortality, need for social assistance and change of residence, at discharge from hospital and at 1 month following discharge. METHODS:Observational, cohort study. SETTING:Acute Geriatric Unit of a Tertiary Teaching Hospital. SUBJECTS:3...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000102541
更新日期:2007-01-01 00:00:00
abstract::The effect of aging on plasma erythropoietin (EPO) levels after acute hemorrhage was investigated in ovariectomized (Ovx) rats. Old (22 months), middle (mid)-aged (14 months) and adult (5-6 months) Ovx rats were studied. Rats were anesthetized with ether and bled by heart puncture (5 ml/kg). They were bled again after...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213666
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Despite declines in cognitive abilities, older adults often perform comparable to younger adults in everyday tasks [J Am Geriatr Soc 1999;47:172-183]. Older adults may compensate for cognitive declines by using more efficient strategies. People often improve their efficiency by switching from an algorithmic ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000446277
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Although white matter changes visible with MRI are generally considered to result from ischemia, it has become clear that these changes also appear in patients with Alzheimer's disease (AD). However, their significance in AD is unknown. OBJECTIVE:We evaluated the clinical significance of white matter change...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000078353
更新日期:2004-07-01 00:00:00
abstract::We studied the effects of factors associated with vascular injury on the production of endothelin-1 (ET-1) in cultured porcine aortic endothelial cells. ET-1 mRNA expression and peptide production in endothelial cells were increased by thrombin, transforming growth factor beta 1 (TGF beta 1), interleukin-1 (IL-1) and ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213360
更新日期:1992-01-01 00:00:00
abstract::The spectrum of aldimine cross-link bonds of skin collagen is dependent on the localization of the examined material. In correlation to this, there is no synchronous behaviour of cross-linkage in the aging process. The age-dependent decrease of HLNL and the increase of DHLNL in the collagen of tail tendon is only unsu...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212268
更新日期:1978-01-01 00:00:00
abstract::To determine the influence of age, disease and other factors on anthropometric indices in elderly subjects aged 70 years and above, body mass index (BMI), arm muscle circumference (AMC), corrected arm muscle area (CAMA), fat-free mass (FFM) and total body fat (TBF) were determined in a random sample of 990 Chinese men...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213679
更新日期:1995-01-01 00:00:00
abstract::We examined the presenting features, clinical course and prognosis in relation to age in 121 patients with primary biliary cirrhosis (PBC) for a mean follow-up of 4.6 years. 35 patients (29%) were over age 65 years at presentation/detection. There was a higher proportion of patients asymptomatic of liver disease in th...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212701
更新日期:1985-01-01 00:00:00
abstract::Acquisition of immunologic self-tolerance by clonal deletion in the thymus is concluded to be a critical process in immune aging and is found to be transiently protected from genetic instability by means of a feedback surveillance which functions at the expense of chronic thymic involution. In the immune control of ma...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000213604
更新日期:1994-01-01 00:00:00
abstract::Typically, subjective memory assessments (be it in form of single items or questionnaires) in old age only weakly correlate with the performance in objective memory tests at cross-section. It thus appears as if individual differences in subjective memory assessments hardly reflect individual differences in memory in o...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000369927
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:To explore predictors of functional improvement or decline in instrumental activities of daily living (IADL) among community-dwelling older people. METHODS:Of all the residents (>or=65 years, n = 1,673) living in Yoita town, Niigata prefecture, Japan, in 2000, 1,544 subjects who participated in the baseline...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000151221
更新日期:2008-01-01 00:00:00
abstract::Tuberculosis is still a major cause of morbidity and mortality worldwide. Recent studies have suggested that even in the developed world its incidence in the elderly is increasing. Symptoms of active tuberculosis are non-specific and less pronounced in the elderly. Radiological features are more likely to be 'atypical...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000052794
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Previous extensive clinical studies, using angiography or ultrasound, investigated the influence of alimentary, medicamentous and other antiatherosclerotic measures on the degree of atherosclerosis. The following signs of regression were found: clinical improvement, changes in tonus of vascular walls, format...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000065248
更新日期:2002-09-01 00:00:00
abstract::The article discusses some aspects demonstrating that a decrease in acetylcholine synthesis in senile dementia of the Alzheimer type (SDAT) is a consequence of the strong decline in glucose turnover in the brain. This becomes obvious by the fact that acetylcoenzyme A, the key substrate of acetylcholine synthesis, is e...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000213592
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Depressed mood may either precede mobility limitation or follow from mobility limitation. OBJECTIVE:To compare mood status among people with manifest mobility limitation, those with preclinical mobility limitation and those without mobility limitation and investigate factors explaining the association betwe...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000098416
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Understanding comorbidity prevalence and the effects of comorbidities in older veterans with lower extremity amputations may aid in assessing patient outcomes, resource use, and facility-level quality of care. OBJECTIVES:To determine the degree to which adding outpatient to inpatient administrative data sou...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000101703
更新日期:2007-01-01 00:00:00
abstract::The distribution of sister chromatid exchange (SCE) points has been analyzed in cultured lymphocytes from three age-groups of 30 females (n = 10; young: 13-20, middle-aged: 30-55, old: 75-84 years). The observed interchromosomal SCE distribution is in good agreement with the results of previous workers, significant ag...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213147
更新日期:1983-01-01 00:00:00
abstract::The activity of ceruloplasmin (CP) increased 3-fold in rat blood between 1 week and 20 months of age, but the difference in CP activity of adult and old rats was only 14%, which still is statistically significant (p less than 0.01). The increase in NaCl and KCl concentrations in vitro resulted in the same exponential ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213261
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:A randomized, double-blind, placebo-controlled clinical trial was conducted to evaluate the effectiveness and safety of peroxide-containing strip-based tooth whitening among subjects with medication-induced hyposalivation. METHODS:Eligibility for this tooth whitening study was limited to dentate adults takin...
journal_title:Gerontology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000235815
更新日期:2009-01-01 00:00:00