An instrument to measure engagement in life: factor analysis and associations with sociodemographic, health and cognition measures.

abstract：BACKGROUND:Myostatin has been proposed as a candidate biomarker for frailty and sarcopenia. However, the relationship of myostatin with these conditions remains inconclusive. OBJECTIVE:To determine the association of serum myostatin concentration with body composition, physical fitness, physical activity level, and fr...

journal_title：Gerontology

authors： Arrieta H,Hervás G,Rezola-Pardo C,Ruiz-Litago F,Iturburu M,Yanguas JJ,Gil SM,Rodriguez-Larrad A,Irazusta J

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Infections due to Streptococcus pneumoniae are the major cause of adult community-acquired pneumonia, especially in elderly persons with chronic medical conditions. Despite their well-documented efficacy against bacteraemic disease and deaths in the elderly population, pneumococcal polysaccharide vaccines ar...

journal_title：Gerontology

authors： Wagner C,Popp W,Posch M,Vlasich C,Rosenberger-Spitzy A

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Wheelchairs are frequently prescribed for residents with mobility impairments in long-term care. Many residents receive poorly fitting wheelchairs, compromising functional independence and mobility, and contributing to subsequent health issues such as pressure ulcers. The extent of this problem and the facto...

journal_title：Gerontology

authors： Giesbrecht EM,Mortenson WB,Miller WC

更新日期：2012-01-01 00:00:00

abstract：:Aging researchers have long been interested in understanding individuals' subjective perceptions of their own memory functioning. Previous research has shown that subjective memory ratings are partly based on memory performance but also reflect the influence of other factors, such as depressive symptoms. The aim of th...

journal_title：Gerontology

authors： Hülür G,Hertzog C,Pearman AM,Gerstorf D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Historically, older adults have been disproportionately affected by disasters. In particular, homebound adults are especially at risk. As one facet of bolstering community resilience, home health agencies have been tasked with improving their patients' disaster preparedness. However, home health practitioner...

journal_title：Gerontology

authors： Wyte-Lake T,Claver M,Tubbesing S,Davis D,Dobalian A

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Creutzfeldt-Jakob disease (CJD) is not only a disorder of the central nervous system but also affects the skeletal muscle. Subclinical skeletal muscle involvement, manifesting as hyper-creatine-kinase (CK)-emia, is rare. CASE REPORT:The patient, a 60-year-old male, developed progressive dementia, accompanie...

journal_title：Gerontology

authors： Finsterer J,Gelpi E

更新日期：2006-01-01 00:00:00

abstract：:Antinuclear antibodies, anticardiolipin antibodies and IgM rheumatoid factor were determined in 300 healthy aged subjects, comparing their prevalence to that in 100 healthy subjects aged between 19 and 44 years and 352 patients under 65 years of age, affected by various systemic rheumatic diseases. Increased productio...

journal_title：Gerontology

authors： Ruffatti A,Rossi L,Calligaro A,Del Ross T,Lagni M,Marson P,Todesco S

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Falls are a significant problem for older adults. Individuals who have sustained a fall come to the attention of health care providers and are at risk of further falls. To promote the highest quality of care and reduce variation in care, a practice guideline is needed. Summarization of evidence regarding fal...

journal_title：Gerontology

authors： Moreland J,Richardson J,Chan D,O'Neill J,Bellissimo A,Grum R,Shanks L

更新日期：2003-03-01 00:00:00

abstract：:Because the body composition effects of growth hormone and insulin-like growth factor-I (IGF-I) are opposite to those of advancing age, it has been hypothesized that the decreased activity of the growth hormone-IGF-I axis is partly responsible for the loss of bone and muscle mass that characterizes normal human aging....

journal_title：Gerontology

authors： Boonen S,Lesaffre E,Aerssens J,Pelemans W,Dequeker J,Bouillon R

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Perceived stress may be a modifiable risk factor for mild cognitive impairment (MCI) and ultimately dementia, but studies on this topic from low- and middle-income countries (LMICs) are lacking. OBJECTIVE:We assessed the association between perceived stress and MCI in six LMICs (China, Ghana, India, Mexico,...

journal_title：Gerontology

authors： Koyanagi A,Oh H,Vancampfort D,Carvalho AF,Veronese N,Stubbs B,Lara E

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Understanding comorbidity prevalence and the effects of comorbidities in older veterans with lower extremity amputations may aid in assessing patient outcomes, resource use, and facility-level quality of care. OBJECTIVES:To determine the degree to which adding outpatient to inpatient administrative data sou...

journal_title：Gerontology

authors： Kurichi JE,Stineman MG,Kwong PL,Bates BE,Reker DM

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Although foot pain has been linked to fall risk, contributions of pain severity, foot posture, or foot function are unclear. These factors were examined in a cohort of older adults. OBJECTIVE:The purpose of this study was to examine the associations of foot pain, severity of foot pain, and measures of foot ...

journal_title：Gerontology

authors： Awale A,Hagedorn TJ,Dufour AB,Menz HB,Casey VA,Hannan MT

更新日期：2017-01-01 00:00:00

abstract：:Although the two-point discrimination test of the skin is a simple test of the sensory nerve function, there have been few studies on age-related changes in the ability to discriminate between two points in a large noninstitutionalized population. In this study we attempted (1) to determine normal values on the two-po...

journal_title：Gerontology

authors： Shimokata H,Kuzuya F

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Previous extensive clinical studies, using angiography or ultrasound, investigated the influence of alimentary, medicamentous and other antiatherosclerotic measures on the degree of atherosclerosis. The following signs of regression were found: clinical improvement, changes in tonus of vascular walls, format...

journal_title：Gerontology

authors： Kunz J

更新日期：2002-09-01 00:00:00

abstract：:Both ageing and vitamin C (VC) deficiency result in immune defect. Since low serum and tissue levels of VC are found in the elderly, we have in a placebo-controlled study, tested the effect of VC supplements (500 mg/day i.m. for 1 month) on various immune parameters. Indeed, VC enhances the proliferative response of T...

journal_title：Gerontology

authors： Kennes B,Dumont I,Brohee D,Hubert C,Neve P

更新日期：1983-01-01 00:00:00

abstract：:(Na+-K+)-ATPase is an enzyme responsible for ionic homeostasis in excitable tissues. Thus, the activity of this enzyme is essential for the maintenance of optimal function of the cerebral cortex. Although abnormalities of cerebral oxidative metabolism have been described in aging, these abnormalities do not appear to ...

journal_title：Gerontology

authors： LaManna JC,Doull G,McCracken K,Harik SI

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Although white matter changes visible with MRI are generally considered to result from ischemia, it has become clear that these changes also appear in patients with Alzheimer's disease (AD). However, their significance in AD is unknown. OBJECTIVE:We evaluated the clinical significance of white matter change...

journal_title：Gerontology

authors： Kono I,Mori S,Nakajima K,Nakagawa M,Watanabe Y,Kizu O,Yamada K,Sakai Y

更新日期：2004-07-01 00:00:00

abstract：:Induced tyrosine aminotransferase from adult and old rat liver was purified and its properties were studied. No differences could be detected for any physicochemical properties studied, i.e. specific activity, molecular weight, isoelectric point, thermostability, sensitivity to trypsin, Km for pyridoxal phosphate. Mor...

journal_title：Gerontology

authors： Szajnert MF,Schapira F

更新日期：1983-01-01 00:00:00

abstract：:We quantitated the skin elastic fibers of the papillary and reticular dermis using specific staining procedure followed by automated computerized image analysis. Fifty skin biopsies of patients consulting for cardiovascular risk factors were studied. The following parameters were estimated: surface area (% of total su...

journal_title：Gerontology

authors： Robert C,Lesty C,Robert AM

更新日期：1988-01-01 00:00:00

abstract：UNLABELLED:BACKGROUND; The link between experiencing difficulties in reading or understanding and non-compliance with drug treatment among seniors is not clearly established. OBJECTIVES:We measured the effect of both difficulties in reading, as well as difficulties in understanding prescription labelling, on non-compl...

journal_title：Gerontology

authors： Moisan J,Gaudet M,Grégoire JP,Bouchard R

更新日期：2002-01-01 00:00:00

abstract：AIM:To investigate acceptance and usage issues in relation to Telehealth products as used by frail older clients of the Transition Care Program and their carers. METHOD:The study design was a quasi-randomised controlled clinical trial. A stratified random sample of participants was allocated to one of five groups usin...

journal_title：Gerontology

authors： Wade R,Shaw K,Cartwright C

更新日期：2012-01-01 00:00:00

abstract：:We have previously shown that lymphocytes from Alzheimer's disease (AD) patients are hypersensitive to ionising radiation, as revealed by their higher levels of dicentrics than those from age-matched, normal individuals. We have now examined the sensitivity of these cells to N-methyl-N-nitrosourea or methyl methanesul...

journal_title：Gerontology

authors： Tobi SE,Neary D,Itzhaki RF

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The common cause account suggests that there is a third factor causing aging effects in both sensory and cognitive functioning, hypothesized to be the integrity of the central nervous system [Lindenberger and Baltes; Psychol Aging 1994;9:339-355]. Importantly, the common cause account was developed based on ...

journal_title：Gerontology

authors： Sternäng O,Jonsson B,Wahlin A,Nyberg L,Nilsson LG

更新日期：2010-01-01 00:00:00

abstract：:Neuron density, volume of the area and total neuron number were measured in the medial preoptic area, supraoptic nucleus, paraventricular nucleus, anterior hypothalamic area, ventromedial nucleus, dorsomedial nucleus and arcuate nucleus of the hypothalamus in young adult male rats (3.5-5 months old) and in old male ra...

journal_title：Gerontology

authors： Peng MT,Hsü HK

更新日期：1982-01-01 00:00:00

abstract：:During the past decade, controversy has raged about the necessity of renal biopsy for the management of the idiopathic nephrotic syndrome. The debate has centered on whether a precise diagnosis is imperative for steroid treatment or whether such therapy can be given blindly. The above question has not been addressed i...

journal_title：Gerontology

authors： Moran D,Korzets Z,Bernheim J,Bernheim J,Yaretzky A

更新日期：1993-01-01 00:00:00

abstract：:The subcellular distribution of estradiol following the in vivo administration of 3H-estradiol, cytosol and nuclear estrogen receptor after in vitro incubation with 3H-estradiol were studied in young adult female rats (3-6 months old) and old female rats (over 18 months old). After intravenous injection of 3H-estradio...

journal_title：Gerontology

authors： Jiang MJ,Peng MT

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:Each year, influenza and its complications account for 10,000-40,000 excess deaths in the United States. Over 80% of these deaths occur among the elderly. The Advisory Committee on Immunization Practices for the US Public Health Service and others recommend that all persons 65 years of age and older as well a...

journal_title：Gerontology

authors： Nichol KL,Margolis KL,Wouremna J,von Sternberg T

更新日期：1996-01-01 00:00:00

abstract：:We use nerve tissue cultures as a model system for studying the mode of action of centrally acting drugs. Neurons in cerebellar cultures retain a number of organ-specific properties including the formation of complex synaptic networks and characteristic bioelectric activity. Electrical activity may be recorded from Pu...

journal_title：Gerontology

authors： Gähwiler BH

更新日期：1978-01-01 00:00:00

abstract：:We examined age- and diet-related alterations in RNA poly(A) tail length using high-resolution gel electrophoresis followed by Northern hybridization. The results demonstrate conclusively that there is no age-related decrease in the size of the Poly(A) tail of RNA isolated from the male Fischer 344 rat. In contrast, o...

journal_title：Gerontology

authors： Kristal BS,Conrad CC,Richarson A,Yu BP

更新日期：1993-01-01 00:00:00

abstract：:We performed 24-hour ambulatory electrocardiographic (Holter) examinations in 50 retired hospital workers (30 men, 20 women), aged 58-85 years (mean age +/- SD: 65.9 +/- 4.6 years), with a normal clinical history, physical examination and baseline ECG. There was a significant difference between daytime and nocturnal m...

journal_title：Gerontology

authors： Ribera JM,Cruz AJ,Zamorano JL,Pérez-Casar F

更新日期：1989-01-01 00:00:00