No neuron loss from hypothalamic nuclei of old male rats.

abstract：:Age-related changes of muscle fiber and collagen content of the diaphragm (DIA) and rectus abdominis (RA) muscles were examined in rats aged 1, 4, 8 and 18 months. The cross-sectional areas of all muscle fiber types (I, IIa, IIb) and the amount of collagen in both DIA and RA increased up to the age of 8 months after w...

journal_title：Gerontology

authors： Rodrigues CJ,Rodrigues Júnior AJ,Bohm GM

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Thyroid hormones have significant effects on the cardiovascular systems. In general, hyperthyroidism is associated with an increased risk of dysrhythmias, while hypothyroidism may cause atherosclerosis. Recent large studies have sought to identify aging-associated changes in thyroid function and their releva...

journal_title：Gerontology

authors： Barbesino G

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To examine the relationships between upper extremity function (UEF) and mortality, need for social assistance and change of residence, at discharge from hospital and at 1 month following discharge. METHODS:Observational, cohort study. SETTING:Acute Geriatric Unit of a Tertiary Teaching Hospital. SUBJECTS:3...

journal_title：Gerontology

authors： Abizanda P,Navarro JL,Romero L,León M,Sánchez-Jurado PM,Domínguez L

更新日期：2007-01-01 00:00:00

abstract：:Metabolic, endocrine and biochemical variables of female hamsters were studied to define age-related alterations in their characteristics. Endurance performance, aerobic capacity and metabolic fuels and hormones were measured and compared in young-adult (2-3 months) and old (16-17 months) hamsters to determine if the ...

journal_title：Gerontology

authors： Nichols JF,Borer KT

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Werner's syndrome, a rare autosomal recessive disorder, is characterized by features of premature aging. Seventy-five percent of the alleles of Japanese patients with Werner's syndrome have one of three major mutations. OBJECTIVE:To determine the genotype of a patient with Werner's syndrome. METHODS:We dia...

journal_title：Gerontology

authors： Nakayama T,Ochiai T,Takahashi Y,Ohkubo K,Hironaga T,Kokubun S

更新日期：2002-07-01 00:00:00

abstract：:Glutamine synthetase (GS) activity was measured in whole brain, different brain areas, liver and heart of 23- to 26-month-old rats, and then compared to matched animals of 3 months. A significant increase of GS activity was found in whole brain (25%) of old rats, as well as in all brain areas studied, but particularly...

journal_title：Gerontology

authors： Cao Danh H,Strolin Benedetti M,Dostert P

更新日期：1985-01-01 00:00:00

abstract：:A profound influence of steroidal (and possibly growth) hormone change during aging on the P-450 functions has been found in male rats. Direct and rapid autonomic nervous controls on glycogen metabolism in the liver is also greatly affected by aging. However, neither the responses of isolated rat hepatocyte preparatio...

journal_title：Gerontology

authors： Kitani K

更新日期：1988-01-01 00:00:00

abstract：:L-tryptophan (L-T) was added at a dose of 150-450 mg daily to eight Parkinsonian patients who developed visual hallucinations with paranoidal features under L-dopa (L-D) treatment (112.5-75 mg daily) in combination with alpha-methyldopa hydrazine (12.5-75 mg daily). In six patients L-T ameliorated the symptomatology b...

journal_title：Gerontology

authors： Rabey JM,Vardi J,Askenazi JJ,Streifler M

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:To explore predictors of functional improvement or decline in instrumental activities of daily living (IADL) among community-dwelling older people. METHODS:Of all the residents (>or=65 years, n = 1,673) living in Yoita town, Niigata prefecture, Japan, in 2000, 1,544 subjects who participated in the baseline...

journal_title：Gerontology

authors： Fujiwara Y,Yoshida H,Amano H,Fukaya T,Liang J,Uchida H,Shinkai S

更新日期：2008-01-01 00:00:00

abstract：:Adult stem cells in mammalian organs play pivotal roles in the maintenance and repair of these organs throughout the life of the adult and maintain the proper homeostasis of a tissue or organ. Among the adult stem cells described to date, mesenchymal stem cells (MSCs) are highlighted for clinical applications because ...

journal_title：Gerontology

authors： Yu KR,Kang KS

更新日期：2013-01-01 00:00:00

abstract：:Age differences in decision-making are of theoretical interest and have important practical implications, but relevant lines of work are distributed across multiple disciplines and often lack integration. The present review proposes an overarching conceptual framework with the aim of connecting disjointed aspects of t...

journal_title：Gerontology

authors： Löckenhoff CE

更新日期：2018-01-01 00:00:00

abstract：:The rates of collagen fibril formation are, under otherwise identical conditions, a function of the age of the acid-soluble rat tail tendon collagen utilized. The rate is most rapid with young adult (165 day) collagen, which exhibits no induction period before collagen multimerization begins. In contrast, 21-day colla...

journal_title：Gerontology

authors： Brooks C,Simons ER

更新日期：1978-01-01 00:00:00

abstract：:The influence of age and smoking on pharmacokinetics of pindolol and propranolol was investigated. Although there was a statistically significant difference in certain pharmacokinetic parameters (maximum plasma concentration, area under the curve, elimination constant and elimination half-life) between elderly patient...

journal_title：Gerontology

authors： Hitzenberger G,Fitscha P,Beveridge T,Nüesch E,Pacha W

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:There are limited psychological data on the quality of life and activities of daily living among elderly Japanese who live alone. OBJECTIVE:The aim of this study was to examine the frequency of apathy and its correlation with activities of daily living and with subjective well-being in elderly people living...

journal_title：Gerontology

authors： Yamashita K,Iijima K,Kobayashi S

更新日期：1999-09-01 00:00:00

abstract：:Alzheimer neurofibrillary changes and senile plaques were found in a variety of distribution patterns and intensities in 50 brains of patients older than 73 years who had been carefully examined for signs of organic dementia in a geriatric unit. As noted by earlier observers, the severity of dementia usually correspon...

journal_title：Gerontology

authors： Ulrich J,Stähelin HB

更新日期：1984-01-01 00:00:00

abstract：:Various parameters of copulatory behavior were examined in intact and castrated testosterone-(T-)treated male rats of various ages ranging from 3 to 27 months. Serum T levels were controlled by subcutaneous implantation of different sizes of T-filled Silastic capsules at the time of castration. In intact male rats, sc...

journal_title：Gerontology

authors： Hsu HK,Hsu C,Yu JY,Peng MT

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:In Japan, vascular dementia (VD) has been responsible for the majority of all dementia cases in both epidemiological and neuropathological studies. Recently, however, several epidemiological investigations have shown that the rate of VD has decreased and senile dementia of the Alzheimer type (SDAT) is now th...

journal_title：Gerontology

authors： Seno H,Ishino H,Inagaki T,Iijima M,Kaku K,Inata T

更新日期：1999-01-01 00:00:00

abstract：:Taurine (TAU) is thought to be a neuromodulator or an inhibitory neurotransmitter in the mammalian brain. In the periphery, TAU is involved in a wide spectrum of physiological functions. One of the most important putative physiological function of TAU is the modulation of cardiovascular activity including blood pressu...

journal_title：Gerontology

authors： Wallace DR,Dawson R Jr

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Previous extensive clinical studies, using angiography or ultrasound, investigated the influence of alimentary, medicamentous and other antiatherosclerotic measures on the degree of atherosclerosis. The following signs of regression were found: clinical improvement, changes in tonus of vascular walls, format...

journal_title：Gerontology

authors： Kunz J

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:While many studies investigate the factors that influence the institutionalisation of older persons, only a few consider one of its most important predictors, namely, the perceived need for institutionalisation. Also referred to as 'desire for institutionalisation', it has mainly been investigated for inform...

journal_title：Gerontology

authors： Dubois MF,Dubuc N,Raîche M,Caron CD,Hébert R

更新日期：2008-01-01 00:00:00

abstract：:Creatine phosphokinase (CPK) has been shown to provide the initial ATP for muscle contraction. The effect of wheel running on CPK levels was compared in hindleg and cardiac muscles of young, intermediate-age and old outbred CW-1 and inbred C57BL mice. Short-term (5 weeks) and long-term (over 12 months) regimens were u...

journal_title：Gerontology

authors： Steinhagen-Thiessen E,Reznick AZ

更新日期：1987-01-01 00:00:00

abstract：:Sera from 40 elderly individuals ranging in age from 60 to 94 years were tested for the presence of antibodies to varicella-zoster virus (VZV)-specific proteins. Sodium dodecylsulfate polyacrylamide gel electrophoresis analysis of lysates of VZV-infected BSC-1 cells labeled with either [35S]methionine or [3H]mannose a...

journal_title：Gerontology

authors： Vafai A,Mahalingam R,Zerbe G,Wellish M,Gilden DH

更新日期：1988-01-01 00:00:00

abstract：:Normal circulating red blood cells (RBCs) and platelets have been shown to have small amounts of IgG on their membranes. The cell-bound IgG may be cytophilic (IgG nonspecifically adsorbed from the plasma) and/or IgG autoantibody. It has been suggested that most of the RBC-bound IgG is on older RBCs and is an autoantib...

journal_title：Gerontology

authors： Garratty G

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Lying on the floor for a long time after falls, regardless of whether an injury results, remains an unsolved health care problem. In order to develop efficient and acceptable fall detection and reaction approaches, it is relevant to improve the understanding of the circumstances and the characteristics of po...

journal_title：Gerontology

authors： Schwickert L,Klenk J,Zijlstra W,Forst-Gill M,Sczuka K,Helbostad JL,Chiari L,Aminian K,Todd C,Becker C

更新日期：2018-01-01 00:00:00

abstract：:The vascular system of 30 old asymptomatic patients (average age 62.5 years) was studied by reflection plethysmography. The plethysmogram (PTG) was recorded from the forefinger of the left hand at rest, during two postural tests (+45 degrees arm-up and -45 degrees arm-down), after physical work, and during the infusio...

journal_title：Gerontology

authors： Strozzi C,Cocco G,Destro A,Padovan G,Abbasciano V,Tosatti S

更新日期：1979-01-01 00:00:00

abstract：:The kinetics of cell proliferation and sister chromatid exchanges (SCE) were studied in blood lymphocytes treated by mitomycin C (MMC) in young and old human donors. In both the young and old donors MMC inhibited cell proliferation. Spontaneous SCE frequency was not age-dependent. In young donors, MMC induced a dose-r...

journal_title：Gerontology

authors： Musilová J,Michalová K,Pacovský V

更新日期：1984-01-01 00:00:00

abstract：:This paper critiques Brand and Markowitsch's viewpoint that the decision-making difficulties experienced by older adults during laboratory-based gambling tasks can be attributed to deficits in executive control and feedback operations. While Brand and Markowitsch provide an important platform with which to understand ...

journal_title：Gerontology

authors： McCarrey AC,Henry JD,Luszcz M

更新日期：2010-01-01 00:00:00

abstract：:One of the problems associated with using random-source dogs to study in vivo vascular responses is their unknown background. Since aging is known to influence vascular responses, unknown variations in age could influence experimental results. The vast majority of aging studies examine arteries in vitro. This study wa...

journal_title：Gerontology

authors： Kaiser L,Ptu S

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Mortality in the intensive care unit (ICU) rises with age, a high basal serum cortisol and a small response to adrenocorticotropin (ACTH) stimulation. Even slight impairment of the adrenal response during severe illness can be lethal. OBJECTIVES:To determine if age is associated with changes in basal or sti...

journal_title：Gerontology

authors： Beale E,Zhu J,Belzberg H

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:Creutzfeldt-Jakob disease (CJD) is not only a disorder of the central nervous system but also affects the skeletal muscle. Subclinical skeletal muscle involvement, manifesting as hyper-creatine-kinase (CK)-emia, is rare. CASE REPORT:The patient, a 60-year-old male, developed progressive dementia, accompanie...

journal_title：Gerontology

authors： Finsterer J,Gelpi E

更新日期：2006-01-01 00:00:00