Aging-related genes in mesenchymal stem cells: a mini-review.

abstract：BACKGROUND:Although cross-sectional studies have demonstrated associations between visual contrast sensitivity and cognitive test performance, it remains unclear whether peripheral visual or perceptual factors explain the association. OBJECTIVE:We aimed at determining whether reducing static contrast of the study stim...

journal_title：Gerontology

authors： Anstey KJ,Butterworth P,Borzycki M,Andrews S

更新日期：2006-01-01 00:00:00

abstract：:To develop a new method for accurately predicting creatinine clearance (Ccr) in the debilitated elderly without urine collections, the total muscle volume of both thighs (MV thigh), as a new predictive parameter, was calculated using computed tomography in 68 debilitated patients aged 61-92 years. A regression line be...

journal_title：Gerontology

authors： Sanaka M,Takano K,Shimakura K,Koike Y,Mineshita S

更新日期：1995-01-01 00:00:00

abstract：:During the past decade, controversy has raged about the necessity of renal biopsy for the management of the idiopathic nephrotic syndrome. The debate has centered on whether a precise diagnosis is imperative for steroid treatment or whether such therapy can be given blindly. The above question has not been addressed i...

journal_title：Gerontology

authors： Moran D,Korzets Z,Bernheim J,Bernheim J,Yaretzky A

更新日期：1993-01-01 00:00:00

abstract：:The distribution of sister chromatid exchange (SCE) points has been analyzed in cultured lymphocytes from three age-groups of 30 females (n = 10; young: 13-20, middle-aged: 30-55, old: 75-84 years). The observed interchromosomal SCE distribution is in good agreement with the results of previous workers, significant ag...

journal_title：Gerontology

authors： Vormittag W

更新日期：1983-01-01 00:00:00

abstract：:Antinuclear antibodies, anticardiolipin antibodies and IgM rheumatoid factor were determined in 300 healthy aged subjects, comparing their prevalence to that in 100 healthy subjects aged between 19 and 44 years and 352 patients under 65 years of age, affected by various systemic rheumatic diseases. Increased productio...

journal_title：Gerontology

authors： Ruffatti A,Rossi L,Calligaro A,Del Ross T,Lagni M,Marson P,Todesco S

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Fall incidents and their negative outcomes represent a considerable problem in hospitals, especially in geriatric wards, and require implementation of strategies to prevent these undesirable events. For this reason, the College of Geriatrics, a body funded by the Belgian Government to set up quality improvem...

journal_title：Gerontology

authors： Coussement J,Dejaeger E,Lambert M,Van Den Noortgate N,De Paepe L,Boonen S,Schoevaerdts D,Milisen K

更新日期：2009-01-01 00:00:00

abstract：AIM:To investigate acceptance and usage issues in relation to Telehealth products as used by frail older clients of the Transition Care Program and their carers. METHOD:The study design was a quasi-randomised controlled clinical trial. A stratified random sample of participants was allocated to one of five groups usin...

journal_title：Gerontology

authors： Wade R,Shaw K,Cartwright C

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Falls are a major cause of morbidity among older people. Multifaceted interventions may be effective in preventing falls and related fractures. OBJECTIVE:To evaluate the cost-effectiveness alongside the REducing Falls with Orthoses and a Multifaceted podiatry intervention (REFORM) trial. METHODS:REFORM was...

journal_title：Gerontology

authors： Corbacho B,Cockayne S,Fairhurst C,Hewitt CE,Hicks K,Kenan AM,Lamb SE,MacIntosh C,Menz HB,Redmond AC,Rodgers S,Scantlebury A,Watson J,Torgerson DJ,on behalf of the REFORM study.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Recruiting older adults, their family members and their home care workers as participants in research studies is particularly complicated. This might be due to medical or cognitive problems of the older adult as well as the high workload and shortage of time experienced by caregivers. The present study compa...

journal_title：Gerontology

authors： Green O,Ayalon L

更新日期：2015-01-01 00:00:00

abstract：:Mechanisms underlying the decreased febrile response in the elderly have not been elucidated. One hypothesis is that elderly persons have a decreased response at the hypothalamic or peripheral effector level to endogenous pyrogen (EP). We studied the response to human monocyte-derived EP in young adult and aged Fische...

journal_title：Gerontology

authors： Tocco-Bradley R,Singer R,Kluger MJ,Kauffman CA

更新日期：1985-01-01 00:00:00

abstract：:In the present study, we examined the changes that occur with age in anti-idiotype-blocked, hapten-augmentable PFC in the mucosal-associated lymph nodes (MLN and BLN) and spleen of various strains of mice. 2-month-old 129/J, AKR/J, and C57L/J mice had a high percentage of hapten-augmentable PFC in their spleen, MLN, a...

journal_title：Gerontology

authors： Szewczuk MR,Wade AW

更新日期：1985-01-01 00:00:00

abstract：:Because the body composition effects of growth hormone and insulin-like growth factor-I (IGF-I) are opposite to those of advancing age, it has been hypothesized that the decreased activity of the growth hormone-IGF-I axis is partly responsible for the loss of bone and muscle mass that characterizes normal human aging....

journal_title：Gerontology

authors： Boonen S,Lesaffre E,Aerssens J,Pelemans W,Dequeker J,Bouillon R

更新日期：1996-01-01 00:00:00

abstract：INTRODUCTION:Many falls in older adults occur during walking and result in lateral falls. The ability to perform a recovery step after balance perturbation determines whether a fall will occur. AIM:To investigate age-related changes in first recovery step kinematics and kinematic adaptations over a wide range of later...

journal_title：Gerontology

authors： Nachmani H,Shani G,Shapiro A,Melzer I

更新日期：2020-01-01 00:00:00

abstract：:The vascular system of 30 old asymptomatic patients (average age 62.5 years) was studied by reflection plethysmography. The plethysmogram (PTG) was recorded from the forefinger of the left hand at rest, during two postural tests (+45 degrees arm-up and -45 degrees arm-down), after physical work, and during the infusio...

journal_title：Gerontology

authors： Strozzi C,Cocco G,Destro A,Padovan G,Abbasciano V,Tosatti S

更新日期：1979-01-01 00:00:00

abstract：:The concentrations of noradrenaline and adrenaline were studied in specimens of the posterior tibial artery obtained from 18 subjects at postmortem examination. The mean noradrenaline concentration was 167 ng/g artery (range 17-449 ng/g) and the mean adrenaline concentration was 5 ng/g (range 0--21 ng/g). There was no...

journal_title：Gerontology

authors： Neubauer B,Christensen NJ

更新日期：1978-01-01 00:00:00

abstract：:As populations age globally, the health of older adults is looming larger on the agendas of public health bodies. In particular, the priority is to ensure that older adults remain healthy, independent, and engaged in their communities. In other words, ensuring that increasing life spans are matched by increasing "heal...

journal_title：Gerontology

authors： Doherty TM,Di Pasquale A,Michel JP,Del Giudice G

更新日期：2020-01-01 00:00:00

abstract：:A profound influence of steroidal (and possibly growth) hormone change during aging on the P-450 functions has been found in male rats. Direct and rapid autonomic nervous controls on glycogen metabolism in the liver is also greatly affected by aging. However, neither the responses of isolated rat hepatocyte preparatio...

journal_title：Gerontology

authors： Kitani K

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Relationships between alcohol consumption and risks for metabolic syndrome in general populations are very controversial. It is unknown whether age influences the relationship between alcohol intake and the prevalence of metabolic syndrome. OBJECTIVE:The purpose of this study was to determine whether age in...

journal_title：Gerontology

authors： Wakabayashi I

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Orthostatic hypotension (OH) is common in older adults and associated with increased morbidity and mortality, loss of independence and high health-care costs. Standing up slowly is a recommended non-pharmacological intervention. However, the effectiveness of this advice has not been well studied. OBJECTIVES...

journal_title：Gerontology

authors： de Bruïne ES,Reijnierse EM,Trappenburg MC,Pasma JH,de Vries OJ,Meskers CG,Maier AB

更新日期：2017-01-01 00:00:00

abstract：:Alloxan diabetes in Swiss mice of both sexes accelerated the ageing of collagen in newly formed cotton pellet granuloma concomitant with its similar effect on dorsal skin. The degree of response of collagen to alloxanization was dependent on the duration of the treatment and the sex of the animal. It is suggested that...

journal_title：Gerontology

authors： Behera HN,Patnaik BK

更新日期：1981-01-01 00:00:00

abstract：:The pharmacokinetics of indomethacin (Indo) was studied in 10 healthy elderly male volunteers (age 67-81 years) following the oral administration of a single 75-mg dose of a sustained release form of Indo. The total and free plasma and erythrocyte concentrations of Indo were determined by a specific high-pressure liqu...

journal_title：Gerontology

authors： Bruguerolle B,Barbeau G,Bélanger PM,Labrecque G

更新日期：1986-01-01 00:00:00

abstract：:A retrospective study was made of 50 consecutive cases of bacteraemia treated in a geriatric unit. The mortality rate was 24%, the highest incidence occurring amongst the cases of hospital-acquired bacteraemia where only 1 of 7 cases survived the infection. Pyrexia, acute confusion, and falls were the commonest presen...

journal_title：Gerontology

authors： Windsor AC

更新日期：1983-01-01 00:00:00

abstract：:Theophylline kinetics were evaluated in 6 elderly (age 65-75 years) and 5 young (age 22-28 years), nonsmoking males following the oral administration of 200 mg of Elixophylline. Theophylline serum concentration in the postabsorptive phase declined in a monoexponential manner. Total body clearance, elimination half-lif...

journal_title：Gerontology

authors： Blouin RA,Erwin WG,Foster TS,Scott S

更新日期：1982-01-01 00:00:00

abstract：:The aim of the study was to examine the characteristics of colorectal cancer in elderly patients. The medical histories of 178 consecutive patients (79 men and 99 women) with colorectal cancer were studied from hospital records. The studied parameters were compared between three age groups: under 65 years old, 65-80 y...

journal_title：Gerontology

authors： Kemppainen M,Räihä I,Rajala T,Sourander L

更新日期：1993-01-01 00:00:00

abstract：:The Zika virus (ZIKV) outbreak in French Polynesia, in 2013, and in Brazil, in 2015, was correlated with neurological complications, which comprised, among others, congenital microcephaly and Guillain-Barré syndrome (GBS), which includes a group of acute autoimmune neuropathies generally reported after respiratory or ...

journal_title：Gerontology

authors： Savino W,Messias CV,Mendes-da-Cruz DA,Passos P,Ferreira AC,Nascimento OJ

更新日期：2017-01-01 00:00:00

abstract：:100 consecutive endoscopies in elderly patients referred with symptoms after previous gastric surgery are reviewed. 57% showed positive findings, and the procedure was found particularly useful in making definitive diagnoses in patients presenting with dyspepsia and upper gastro-intestinal bleeding. The incidence of g...

journal_title：Gerontology

authors： Gibbins FJ,Gupta SD,Sen I

更新日期：1985-01-01 00:00:00

abstract：:Patients over 65 years of age admitted to an ophthalmic ward were routinely screened in a standard way practiced in Geriatric Assessment Units. The previous drug therapy of all patients was particularly noted. A classification of the patients with undetected pathology was made and an attempt to categorise the percenta...

journal_title：Gerontology

authors： Andrews J,Pandita-Gunawardena ND,Suntharalingham M

更新日期：1977-01-01 00:00:00

abstract：:To determine the influence of age, disease and other factors on anthropometric indices in elderly subjects aged 70 years and above, body mass index (BMI), arm muscle circumference (AMC), corrected arm muscle area (CAMA), fat-free mass (FFM) and total body fat (TBF) were determined in a random sample of 990 Chinese men...

journal_title：Gerontology

authors： Woo J,Ho SC,Sham A,Yuen YK,Chan SG

更新日期：1995-01-01 00:00:00

abstract：:The effect of age on the compositional analysis of human Descemet's membrane was examined. Membranes were obtained from human corneas ranging from 0.5 to 95 years and purified by sodium dodecyl sulfate (SDS) extraction. Substantial age-related changes were obtained in the amino acid compositions of the SDS-insoluble b...

journal_title：Gerontology

authors： Freeman IL,Vergnes JP,Brown SI

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:The chronic stress of providing care for a spouse suffering from Alzheimer's disease has been associated with an increased risk for coronary artery disease and overall mortality. Procoagulant changes are kindled by mental stress, and they are prospectively associated with atherothrombotic events. OBJECTIVE:...

journal_title：Gerontology

authors： von Kanel R,Dimsdale JE,Adler KA,Patterson TL,Mills PJ,Grant I

更新日期：2005-01-01 00:00:00