Effect of age on the febrile response of rats to endogenous pyrogen.

abstract：BACKGROUND:Perceived stress may be a modifiable risk factor for mild cognitive impairment (MCI) and ultimately dementia, but studies on this topic from low- and middle-income countries (LMICs) are lacking. OBJECTIVE:We assessed the association between perceived stress and MCI in six LMICs (China, Ghana, India, Mexico,...

journal_title：Gerontology

authors： Koyanagi A,Oh H,Vancampfort D,Carvalho AF,Veronese N,Stubbs B,Lara E

更新日期：2019-01-01 00:00:00

abstract：:The spectrum of aldimine cross-link bonds of skin collagen is dependent on the localization of the examined material. In correlation to this, there is no synchronous behaviour of cross-linkage in the aging process. The age-dependent decrease of HLNL and the increase of DHLNL in the collagen of tail tendon is only unsu...

journal_title：Gerontology

authors： Ruiz-Torres A

更新日期：1978-01-01 00:00:00

abstract：:Creatine phosphokinase (CPK) has been shown to provide the initial ATP for muscle contraction. The effect of wheel running on CPK levels was compared in hindleg and cardiac muscles of young, intermediate-age and old outbred CW-1 and inbred C57BL mice. Short-term (5 weeks) and long-term (over 12 months) regimens were u...

journal_title：Gerontology

authors： Steinhagen-Thiessen E,Reznick AZ

更新日期：1987-01-01 00:00:00

abstract：:Tuberculosis is still a major cause of morbidity and mortality worldwide. Recent studies have suggested that even in the developed world its incidence in the elderly is increasing. Symptoms of active tuberculosis are non-specific and less pronounced in the elderly. Radiological features are more likely to be 'atypical...

journal_title：Gerontology

authors： Packham S

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:compared with other vertebrate taxa, mammals possess a very limited capacity for appendage regeneration. The antlers of deer are an exception in that they are periodically lost and fully regenerated throughout the life of an individual. OBJECTIVE:in this paper we compare certain aspects of antler regenerati...

journal_title：Gerontology

authors： Kierdorf U,Kierdorf H

更新日期：2011-01-01 00:00:00

abstract：:The effects of ovine corticotropin releasing factor (o-CRF) on the secretions of ACTH, cortisol, dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) were studied in the healthy young and elderly male individuals. o-CRF caused significant elevations of plasma ACTH, cortisol and DHEA concentrations...

journal_title：Gerontology

authors： Ohashi M,Fujio N,Kato K,Nawata H,Ibayashi H

更新日期：1986-01-01 00:00:00

abstract：:The conditioned avoidance response and the cerebral levels of dopamine and noradrenaline have been studied in control rats and in rats submitted to a hypobaric hypoxia. A protection against the effects of hypoxia was induced by both dihydroergocornine (20 microgram/kg) and dihydroergocryptine (100 microgram/kg), and t...

journal_title：Gerontology

authors： Boismare F,Le Poncin M,Lefrançois J

更新日期：1978-01-01 00:00:00

abstract：:Adhesion molecules, such as leukocyte-function-associated antigen (LFA-1 or CD11a/CD18), intercellular adhesion molecule 1 (ICAM-1 or CD54) and Hermes antigen (HCAM or CD44), have important roles in many adhesive interactions involving cells of the immune system. Since it has been shown that many immunological alterat...

journal_title：Gerontology

authors： Chiricolo M,Morini MC,Mancini R,Beltrandi E,Belletti D,Conte R

更新日期：1995-01-01 00:00:00

abstract：:100 consecutive endoscopies in elderly patients referred with symptoms after previous gastric surgery are reviewed. 57% showed positive findings, and the procedure was found particularly useful in making definitive diagnoses in patients presenting with dyspepsia and upper gastro-intestinal bleeding. The incidence of g...

journal_title：Gerontology

authors： Gibbins FJ,Gupta SD,Sen I

更新日期：1985-01-01 00:00:00

abstract：:Cell surface of chick fibroblasts were labelled by a short treatment with 125I in presence of lactoperoxidase. A glycoprotein (220,000 molec. wt) was iodinated and was present in a more exposed position or in greater amounts at the surface of old phase III cells compared to young phase II cells. The findings extend ou...

journal_title：Gerontology

authors： Courtois Y,Hughes RC

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:To explore predictors of functional improvement or decline in instrumental activities of daily living (IADL) among community-dwelling older people. METHODS:Of all the residents (>or=65 years, n = 1,673) living in Yoita town, Niigata prefecture, Japan, in 2000, 1,544 subjects who participated in the baseline...

journal_title：Gerontology

authors： Fujiwara Y,Yoshida H,Amano H,Fukaya T,Liang J,Uchida H,Shinkai S

更新日期：2008-01-01 00:00:00

abstract：:The kinetics of cell proliferation and sister chromatid exchanges (SCE) were studied in blood lymphocytes treated by mitomycin C (MMC) in young and old human donors. In both the young and old donors MMC inhibited cell proliferation. Spontaneous SCE frequency was not age-dependent. In young donors, MMC induced a dose-r...

journal_title：Gerontology

authors： Musilová J,Michalová K,Pacovský V

更新日期：1984-01-01 00:00:00

abstract：:The effect of ageing on the threshold firing rate of motor units from the first dorsal interosseous muscle was investigated. Two groups of 9 healthy male subjects between the ages of 20-29 and 60-69 years took part in the study. The threshold firing rate of motor units in young subjects showed close agreement with pre...

journal_title：Gerontology

authors： Newton JP,Yemm R,McDonagh MJ

更新日期：1988-01-01 00:00:00

abstract：:When mouse peritoneal macrophages were cultured with oxidized human low density lipoprotein (ox-LDL), storage of ceroid-like pigments was observed within the cells by light and fluorescent microscopy, and fluorescence spectrophotometry. The fluorescent products exhibit the characteristics of Schiff base structures, ha...

journal_title：Gerontology

authors： Shimasaki H,Maeba R,Tachibana R,Ueta N

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Relationships between alcohol consumption and risks for metabolic syndrome in general populations are very controversial. It is unknown whether age influences the relationship between alcohol intake and the prevalence of metabolic syndrome. OBJECTIVE:The purpose of this study was to determine whether age in...

journal_title：Gerontology

authors： Wakabayashi I

更新日期：2012-01-01 00:00:00

abstract：:Alteration in lipid peroxidation products such as lipid peroxides, lipid hydroperoxides were studied in different regions of CNS of ageing rats (13, 26, 52, 78 and 104 weeks). The levels of lipid peroxide and lipid hydroperoxide were increased in various regions of brain and spinal cord. However, the activity of super...

journal_title：Gerontology

authors： Gupta A,Hasan M,Chander R,Kapoor NK

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:The aim of the present article is to discuss the potential of gene therapy for thymic hormones as a novel therapeutic strategy to treat dyshomeostatic states associated with athymia, as Di George syndrome, or hypothymic conditions like those associated with AIDS, chronic stress or aging. First ...

journal_title：Gerontology

authors： Goya RG,Cónsole G,Hereñú C,Brown O,Rimoldi OJ

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Understanding comorbidity prevalence and the effects of comorbidities in older veterans with lower extremity amputations may aid in assessing patient outcomes, resource use, and facility-level quality of care. OBJECTIVES:To determine the degree to which adding outpatient to inpatient administrative data sou...

journal_title：Gerontology

authors： Kurichi JE,Stineman MG,Kwong PL,Bates BE,Reker DM

更新日期：2007-01-01 00:00:00

abstract：:Prospective surveillance of nosocomial infection was conducted at seven skilled proprietary nursing facilities in Orange County, Calif., USA. The average incidence of facility-acquired infection was 5.2 infections/1,000 patient days. The most common source of infection was urinary tract (47%), followed by respiratory ...

journal_title：Gerontology

authors： Lee YL,Thrupp LD,Friis RH,Fine M,Maleki P,Cesario TC

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The total cholesterol concentration decreases with age in older people. The reasons for this phenomenon are controversial. This study investigated the hypothesis that poor health status is a determinant of the inverse association between age and cholesterol in older persons. METHODS:Cross-sectional study of...

journal_title：Gerontology

authors： Volpato S,Zuliani G,Guralnik JM,Palmieri E,Fellin R

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:The results of the very few histochemical studies that have been performed so far on the lectin-binding profile of normal human epidermis are mostly controversial; thus, the carbohydrate residue composition of the cell surface in the latter still remains in dispute and the possible alterations in the epiderm...

journal_title：Gerontology

authors： Georgiou S,Pasmatzi E,Monastirli A,Sakkis T,Alachioti S,Tsambaos D

更新日期：2005-05-01 00:00:00

abstract：:The maximal glucocorticoid responsiveness and the adaptation degree are reduced in old rat liver as demonstrated by cortisol stimulation of RNA polymerases. Nevertheless the concentration of unoccupied 3H-dexamethasone binding sites in molybdate-stabilized cytosol of adrenalectomized old animals is significantly incre...

journal_title：Gerontology

authors： Martin H,Martin R

更新日期：1988-01-01 00:00:00

abstract：:The distribution of sister chromatid exchange (SCE) points has been analyzed in cultured lymphocytes from three age-groups of 30 females (n = 10; young: 13-20, middle-aged: 30-55, old: 75-84 years). The observed interchromosomal SCE distribution is in good agreement with the results of previous workers, significant ag...

journal_title：Gerontology

authors： Vormittag W

更新日期：1983-01-01 00:00:00

abstract：:The eukaryotic stress response involves translational suppression of non-housekeeping proteins and the sequestration of unnecessary mRNA transcripts into stress granules (SGs). This process is dependent on mRNA-binding proteins (RBPs) that interact with capped mRNA transcripts through RNA recognition motifs, and exhib...

journal_title：Gerontology

authors： Vanderweyde T,Youmans K,Liu-Yesucevitz L,Wolozin B

更新日期：2013-01-01 00:00:00

abstract：AIM:To investigate acceptance and usage issues in relation to Telehealth products as used by frail older clients of the Transition Care Program and their carers. METHOD:The study design was a quasi-randomised controlled clinical trial. A stratified random sample of participants was allocated to one of five groups usin...

journal_title：Gerontology

authors： Wade R,Shaw K,Cartwright C

更新日期：2012-01-01 00:00:00

abstract：:Over the past decades, information about the characteristics of attractiveness has accumulated. We know about eight pillars of beauty, among them youthfulness, symmetry, hormone markers and body odor. But what is the biological function of these attractive signals? Is there one common function to be found in all eight...

journal_title：Gerontology

authors： Oberzaucher E,Grammer K

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:A randomized, double-blind, placebo-controlled clinical trial was conducted to evaluate the effectiveness and safety of peroxide-containing strip-based tooth whitening among subjects with medication-induced hyposalivation. METHODS:Eligibility for this tooth whitening study was limited to dentate adults takin...

journal_title：Gerontology

authors： Papas AS,Kugel G,Singh M,Barker ML,Gerlach RW

更新日期：2009-01-01 00:00:00

abstract：:New neurons are continuously generated and added to neural circuits in the adult brain. However, increasing age imposes changes in neural progenitor cells and their microenvironment that lead to a reduction of neurogenesis. Age-related decreased production of new neurons in the neurogenic dentate gyrus has been associ...

journal_title：Gerontology

authors： Seib DR,Martin-Villalba A

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Reference values are usually defined based on blood samples from healthy men or nonpregnant women in the age range of 20-50 years. These values are not optimal for elderly patients, as many biological markers change over time and adequate reference values are important for correct clinical decisions. OBJECT...

journal_title：Gerontology

authors： Carlsson L,Lind L,Larsson A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:A large proportion of falls in older people are caused by slipping. Previous occupational safety research suggests that inadequate footwear may contribute to slipping accidents; however, no studies have assessed the slip resistance of casual footwear. OBJECTIVE:To evaluate the slip resistance of different t...

journal_title：Gerontology

authors： Menz HB,Lord ST,McIntosh AS

更新日期：2001-05-01 00:00:00