Autoantibodies of systemic rheumatic diseases in the healthy elderly.

Abstract:

:Antinuclear antibodies, anticardiolipin antibodies and IgM rheumatoid factor were determined in 300 healthy aged subjects, comparing their prevalence to that in 100 healthy subjects aged between 19 and 44 years and 352 patients under 65 years of age, affected by various systemic rheumatic diseases. Increased production of IgM rheumatoid factor and antinuclear and anticardiolipin antibodies was found as characteristic of aged humans, and suggested that a correction for age should be considered in evaluating the clinical significance of autoantibody profiles in elderly patients.

journal_name

Gerontology

journal_title

Gerontology

authors

Ruffatti A,Rossi L,Calligaro A,Del Ross T,Lagni M,Marson P,Todesco S

doi

10.1159/000213183

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

104-11

issue

2

eissn

0304-324X

issn

1423-0003

journal_volume

36

pub_type

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