Characteristics of colorectal cancer in elderly patients.

abstract：:Different approaches using cell culture techniques to study the biology of aging are critically described. Most of the studies concerned the relationship between cell division potential and aging. The growth potential of cells is fundamental for aging of the organism, since it relates to phenomena such as the regenera...

journal_title：Gerontology

authors： Macieira-Coelho A

更新日期：2000-03-01 00:00:00

abstract：:Morphometric measurements have been carried out on the human myenteric esophageal neurons at the ages of 20-40 and more than 70 years. The number of neurons decreases after 70 years of age, which is accompanied by an increase in the sizes of the neurons. In percentage terms the decrease in the number of neurons in the...

journal_title：Gerontology

authors： Meciano Filho J,Carvalho VC,de Souza RR

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:The chronic stress of providing care for a spouse suffering from Alzheimer's disease has been associated with an increased risk for coronary artery disease and overall mortality. Procoagulant changes are kindled by mental stress, and they are prospectively associated with atherothrombotic events. OBJECTIVE:...

journal_title：Gerontology

authors： von Kanel R,Dimsdale JE,Adler KA,Patterson TL,Mills PJ,Grant I

更新日期：2005-01-01 00:00:00

abstract：:The effects of ageing and of 6 months of Hydergine treatment on lipofuscin deposition within the cytoplasma of pyramidal neurons of rat prefrontal cortex, hippocampus (fields CA1 and CA3) and of Purkinje neurons were assessed microfluorimetrically. No lipofuscin autofluorescence was detected in the nerve cell populati...

journal_title：Gerontology

authors： Amenta D,Ferrante F,Franch F,Amenta F

更新日期：1988-01-01 00:00:00

abstract：:Aging is associated with far-reaching changes in physiological functions resulting in morbidity and ultimately death. Age-related frailty, insecurity and reduced physical activity contribute to a progressive loss of muscle mass and function, commonly referred to as sarcopenia. Due to the increase in life expectancy in...

journal_title：Gerontology

authors： Arnold AS,Egger A,Handschin C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Aging may be defined as gradual and progressive changes in an organism that increase the probability of death. Accumulating evidence now indicates that the sum of deleterious free radical reactions going on continuously throughout cells and tissues constitutes the aging process or is a major contributor to i...

journal_title：Gerontology

authors： Martins Chaves M,Prates Rodrigues AL,Pereira dos Reis A,Gerzstein NC,Nogueira-Machado JA

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Irrelevant unexpected stimuli elicit various types of inhibitory processes modulated by ongoing activity. An index of the inhibitory processes, namely the N2b and P3a event-related potentials (ERP), shows marked age-related differences. OBJECTIVE:In this experiment, we attempted to separate the effects of i...

journal_title：Gerontology

authors： Pató L,Czigler I

更新日期：2011-01-01 00:00:00

abstract：:The rates of collagen fibril formation are, under otherwise identical conditions, a function of the age of the acid-soluble rat tail tendon collagen utilized. The rate is most rapid with young adult (165 day) collagen, which exhibits no induction period before collagen multimerization begins. In contrast, 21-day colla...

journal_title：Gerontology

authors： Brooks C,Simons ER

更新日期：1978-01-01 00:00:00

abstract：:A morphometric analysis of neuronal loss during normal aging was performed in the nucleus basalis Meynert complex of the basal forebrain (Nbm) (nucleus septi medialis, nucleus of Broca's diagonal band, nucleus basalis) and the ciliary ganglion, a peripheral cholinergic structure, in patients free of neurological and p...

journal_title：Gerontology

authors： Bigl V,Arendt T,Fischer S,Fischer S,Werner M,Arendt A

更新日期：1987-01-01 00:00:00

abstract：UNLABELLED:BACKGROUND; The link between experiencing difficulties in reading or understanding and non-compliance with drug treatment among seniors is not clearly established. OBJECTIVES:We measured the effect of both difficulties in reading, as well as difficulties in understanding prescription labelling, on non-compl...

journal_title：Gerontology

authors： Moisan J,Gaudet M,Grégoire JP,Bouchard R

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Constipation and lower urinary tract symptoms (LUTS) very frequently occur in the elderly, and several reports have suggested that dysfunction in either one of these systems may affect the other. Most studies correlating rectal and bladder dysfunction, however, have been carried out in children or young wome...

journal_title：Gerontology

authors： Charach G,Greenstein A,Rabinovich P,Groskopf I,Weintraub M

更新日期：2001-03-01 00:00:00

abstract：:Hydrogen breath testing (HBT) is frequently used as an alternative to small bowel aspiration in the diagnosis of small intestinal bacterial overgrowth (SIBO). The role of the glucose HBT was assessed in 30 elderly patients. A positive HBT was recorded in 15 of 20 SIBO cases and 7 of 10 culture negatives (sensitivity 7...

journal_title：Gerontology

authors： Mac Mahon M,Gibbons N,Mullins E,O'Moore RR,Keane CT,Walsh JB,Coakley D

更新日期：1996-01-01 00:00:00

abstract：:Various parameters of copulatory behavior were examined in intact and castrated testosterone-(T-)treated male rats of various ages ranging from 3 to 27 months. Serum T levels were controlled by subcutaneous implantation of different sizes of T-filled Silastic capsules at the time of castration. In intact male rats, sc...

journal_title：Gerontology

authors： Hsu HK,Hsu C,Yu JY,Peng MT

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Diabetes is common in elderly persons and is highly prevalent in Mexican Americans. Little is known about factors associated with the incidence of diabetes complications. OBJECTIVE:To examine the social, demographic and health factors associated with a 7-year incidence of diabetes complications among older ...

journal_title：Gerontology

authors： Kaushik VP,Al Snih S,Ray LA,Raji MA,Markides KS,Goodwin JS

更新日期：2007-01-01 00:00:00

abstract：:Protein malnutrition is associated with a decreased febrile and acute phase response to infection and increased mortality. To elucidate a cause for this poor response, we assessed the effect of chronic protein malnutrition on monocyte production of the pyrogens interleukin-1 (IL-1) and tumor necrosis factor (TNF). Thi...

journal_title：Gerontology

authors： Bradley SF,Vibhagool A,Fabrick S,Terpenning MS,Kauffman CA

更新日期：1990-01-01 00:00:00

abstract：:(Na+-K+)-ATPase is an enzyme responsible for ionic homeostasis in excitable tissues. Thus, the activity of this enzyme is essential for the maintenance of optimal function of the cerebral cortex. Although abnormalities of cerebral oxidative metabolism have been described in aging, these abnormalities do not appear to ...

journal_title：Gerontology

authors： LaManna JC,Doull G,McCracken K,Harik SI

更新日期：1983-01-01 00:00:00

abstract：:Two kinds of evidence, taken in conjunction, indicate that Orgel's theory is inapplicable to a wide range of disorders of senescence in man. The age dependence and the anatomical distribution of the lesions of such disorders imply a Burnet type 'forbidden clone' theory of ageing. We describe the difficulty of establis...

journal_title：Gerontology

authors： Burch PR,Jackson D

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:There are limited psychological data on the quality of life and activities of daily living among elderly Japanese who live alone. OBJECTIVE:The aim of this study was to examine the frequency of apathy and its correlation with activities of daily living and with subjective well-being in elderly people living...

journal_title：Gerontology

authors： Yamashita K,Iijima K,Kobayashi S

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:The oral cavity is a reservoir for colonization and infection of systemic organs by pathogenic bacteria. It is understood that aging, tooth eruption, hormonal changes, active disease, oral hygiene, and other factors have an influence on biofilm formation and bacterial accumulation in the oral cavity. OBJECT...

journal_title：Gerontology

authors： Senpuku H,Sogame A,Inoshita E,Tsuha Y,Miyazaki H,Hanada N

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Previous extensive clinical studies, using angiography or ultrasound, investigated the influence of alimentary, medicamentous and other antiatherosclerotic measures on the degree of atherosclerosis. The following signs of regression were found: clinical improvement, changes in tonus of vascular walls, format...

journal_title：Gerontology

authors： Kunz J

更新日期：2002-09-01 00:00:00

abstract：:The maximal glucocorticoid responsiveness and the adaptation degree are reduced in old rat liver as demonstrated by cortisol stimulation of RNA polymerases. Nevertheless the concentration of unoccupied 3H-dexamethasone binding sites in molybdate-stabilized cytosol of adrenalectomized old animals is significantly incre...

journal_title：Gerontology

authors： Martin H,Martin R

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Perceived stress may be a modifiable risk factor for mild cognitive impairment (MCI) and ultimately dementia, but studies on this topic from low- and middle-income countries (LMICs) are lacking. OBJECTIVE:We assessed the association between perceived stress and MCI in six LMICs (China, Ghana, India, Mexico,...

journal_title：Gerontology

authors： Koyanagi A,Oh H,Vancampfort D,Carvalho AF,Veronese N,Stubbs B,Lara E

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Declines in physical fitness can notably affect healthy aging of older adults. Multimodal exercise training regimen such as mind-body interventions (MBIs) has been reported to mitigate these aging-related declines of physical function. This meta-analytical review aimed at pooling the effects of MBIs on phy...

journal_title：Gerontology

authors： Ebner SA,Meikis L,Morat M,Held S,Morat T,Donath L

更新日期：2021-01-27 00:00:00

abstract：:New neurons are continuously generated and added to neural circuits in the adult brain. However, increasing age imposes changes in neural progenitor cells and their microenvironment that lead to a reduction of neurogenesis. Age-related decreased production of new neurons in the neurogenic dentate gyrus has been associ...

journal_title：Gerontology

authors： Seib DR,Martin-Villalba A

更新日期：2015-01-01 00:00:00

abstract：:Alloxan diabetes in Swiss mice of both sexes accelerated the ageing of collagen in newly formed cotton pellet granuloma concomitant with its similar effect on dorsal skin. The degree of response of collagen to alloxanization was dependent on the duration of the treatment and the sex of the animal. It is suggested that...

journal_title：Gerontology

authors： Behera HN,Patnaik BK

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Functional and physiological declines in advancing age may be significant limiting factors in reduced physical activity. Sarcopenia of aging, as a normative process or disease, cannot entirely explain reduced physical activity in the elderly. OBJECTIVE:The purpose of the study was to investigate the relatio...

journal_title：Gerontology

authors： Carmeli E,Reznick AZ,Coleman R,Carmeli V

更新日期：2000-09-01 00:00:00

abstract：:During a winter epidemic of A/H1N1 influenza virus, we evaluated the protection conferred by vaccination of 285 residents of a nursing home. Fifteen of 204 members of the nursing staff were also vaccinated. Serological determinations were performed before and after vaccination using radial hemolysis (RH) and neuramini...

journal_title：Gerontology

authors： Odelin MF,Pozzetto B,Aymard M,Defayolle M,Jolly-Million J

更新日期：1993-01-01 00:00:00

abstract：:We review findings on spousal interrelations in old age in such key domains as cognition, well-being, and health. Therein, we demonstrate that spousal interrelations may extend developmental options but may also make an individual vulnerable to the experience of loss. We address theoretical questions concerning possib...

journal_title：Gerontology

authors： Hoppmann C,Gerstorf D

更新日期：2009-01-01 00:00:00

abstract：:Historically, family ties have been understood as the primary source of support for aging adults, and past empirical and theoretical work has highlighted the tendency of older adults to focus on close family. However, in line with demographic changes and historical increases in the diversity of social structures, frie...

journal_title：Gerontology

authors： Fiori KL,Windsor TD,Huxhold O

更新日期：2020-01-01 00:00:00

abstract：:Alteration in lipid peroxidation products such as lipid peroxides, lipid hydroperoxides were studied in different regions of CNS of ageing rats (13, 26, 52, 78 and 104 weeks). The levels of lipid peroxide and lipid hydroperoxide were increased in various regions of brain and spinal cord. However, the activity of super...

journal_title：Gerontology

authors： Gupta A,Hasan M,Chander R,Kapoor NK

更新日期：1991-01-01 00:00:00