Abstract:
:During a winter epidemic of A/H1N1 influenza virus, we evaluated the protection conferred by vaccination of 285 residents of a nursing home. Fifteen of 204 members of the nursing staff were also vaccinated. Serological determinations were performed before and after vaccination using radial hemolysis (RH) and neuraminidase inhibition (NI) tests. In the outbreak period, only one influenza case was noted in the vaccinated elderly and none among the vaccinated nursing staff. On the other hand, 38 cases (20%) occurred in the unvaccinated hospital personnel. Twenty-one percent of the elderly people exhibited seroconversion to the vaccinal strain by RH and NI while 27 and 20% of the vaccinated nursing staff seroconverted by the same tests, respectively. Thus, the clinical protection conferred by influenza vaccination was excellent and much greater than expected from serological results.
journal_name
Gerontologyjournal_title
Gerontologyauthors
Odelin MF,Pozzetto B,Aymard M,Defayolle M,Jolly-Million Jdoi
10.1159/000213520subject
Has Abstractpub_date
1993-01-01 00:00:00pages
109-16issue
2eissn
0304-324Xissn
1423-0003journal_volume
39pub_type
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