Effects of novelty on event-related potentials: aging and stimulus replacement.

abstract：BACKGROUND:Mortality in the intensive care unit (ICU) rises with age, a high basal serum cortisol and a small response to adrenocorticotropin (ACTH) stimulation. Even slight impairment of the adrenal response during severe illness can be lethal. OBJECTIVES:To determine if age is associated with changes in basal or sti...

journal_title：Gerontology

authors： Beale E,Zhu J,Belzberg H

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:The oral cavity is a reservoir for colonization and infection of systemic organs by pathogenic bacteria. It is understood that aging, tooth eruption, hormonal changes, active disease, oral hygiene, and other factors have an influence on biofilm formation and bacterial accumulation in the oral cavity. OBJECT...

journal_title：Gerontology

authors： Senpuku H,Sogame A,Inoshita E,Tsuha Y,Miyazaki H,Hanada N

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Previous studies have shown links between cognitive impairment and hypertension as well as mortality. However, combined effects of these two conditions on mortality have not been fully explored. OBJECTIVE:To assess the combined effect of cognitive impairment and hypertension on all-cause mortality among the...

journal_title：Gerontology

authors： Gombojav B,Yi SW,Sull JW,Nam CM,Ohrr H

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Nerve growth factor (NGF), discovered because of its action on cells in the peripheral and the central nervous system, is now known to act also on immune cells in developing and adult subjects. Whether peripheral lymphocytes of aged subjects are responsive to this molecule is less clear. OBJECTIVE:Aim of ou...

journal_title：Gerontology

authors： Antonelli A,Bracci-Laudiero L,Aloe L

更新日期：2003-05-01 00:00:00

abstract：:The biological rhythms of rectal temperature were documented in young (circadian variations) and elderly (circadian and seasonal variations) human subjects either in apparent good health or suffering from senile dementia of Alzheimer type (SDAT). All the subjects were synchronized. Data obtained showed a decrease of t...

journal_title：Gerontology

authors： Touitou Y,Reinberg A,Bogdan A,Auzéby A,Beck H,Touitou C

更新日期：1986-01-01 00:00:00

abstract：:Dementia is a symptom of a variety of specific structural brain diseases as well as several system degenerations. Alzheimer's disease presently is the commonest cause in the developed world, causing a cortical-subcortical degeneration of ascending cholinergic neurons and large pyramidal cells in the cerebral cortex. C...

journal_title：Gerontology

authors： Plum F

更新日期：1986-01-01 00:00:00

abstract：UNLABELLED:BACKGROUND; The link between experiencing difficulties in reading or understanding and non-compliance with drug treatment among seniors is not clearly established. OBJECTIVES:We measured the effect of both difficulties in reading, as well as difficulties in understanding prescription labelling, on non-compl...

journal_title：Gerontology

authors： Moisan J,Gaudet M,Grégoire JP,Bouchard R

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:In Germany, there is an ongoing concern about the high prevalence of underweight on admission to health-care institutions. In order to assess possible sex-specific differences, the aim of this study is to provide valid figures about the prevalence and risk factors of underweight of men and women in German nur...

journal_title：Gerontology

authors： Strube-Lahmann S,Müller-Werdan U,Norman K,Skarabis H,Lahmann NA

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:Research on the relationship between vestibular function and falls in older people is sparse. The perception of the postural vertical (PPV) provides an indicator measure of vestibular (otolith) function in the absence of visual input and diminished somatosensory feedback. OBJECTIVE:This study examined wheth...

journal_title：Gerontology

authors： Menant JC,St George RJ,Fitzpatrick RC,Lord SR

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The chronic stress of providing care for a spouse suffering from Alzheimer's disease has been associated with an increased risk for coronary artery disease and overall mortality. Procoagulant changes are kindled by mental stress, and they are prospectively associated with atherothrombotic events. OBJECTIVE:...

journal_title：Gerontology

authors： von Kanel R,Dimsdale JE,Adler KA,Patterson TL,Mills PJ,Grant I

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Developmental researchers use a variety of research designs to examine aging-related changes. Most longitudinal studies of aging are based on research designs that feature successive, widely spaced, assessments to estimate changes in cognitive performance. Such designs assume that short-term variations in co...

journal_title：Gerontology

authors： Martin M,Hofer SM

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:There are limited psychological data on the quality of life and activities of daily living among elderly Japanese who live alone. OBJECTIVE:The aim of this study was to examine the frequency of apathy and its correlation with activities of daily living and with subjective well-being in elderly people living...

journal_title：Gerontology

authors： Yamashita K,Iijima K,Kobayashi S

更新日期：1999-09-01 00:00:00

abstract：:We studied the effects of factors associated with vascular injury on the production of endothelin-1 (ET-1) in cultured porcine aortic endothelial cells. ET-1 mRNA expression and peptide production in endothelial cells were increased by thrombin, transforming growth factor beta 1 (TGF beta 1), interleukin-1 (IL-1) and ...

journal_title：Gerontology

authors： Maemura K,Kurihara H,Morita T,Oh-hashi Y,Yazaki Y

更新日期：1992-01-01 00:00:00

abstract：:Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulat...

journal_title：Gerontology

authors： Nagy V,Penninger JM

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Six-metre walking speed (SMWS) is a commonly used test for measuring functional performance in older people. However, apart from lower limb strength, few studies have examined the range of physiological and psychological factors that influence performance in this test. OBJECTIVE:To investigate the relative ...

journal_title：Gerontology

authors： Tiedemann A,Sherrington C,Lord SR

更新日期：2005-11-01 00:00:00

abstract：:Cyclic AMP-dependent and -independent protein kinase have been isolated from livers of rats at 3, 9, 18 and 30 months of age. A preliminary characterization reported here reveals that in addition to a decrease in their activities due to ageing and a likely shift to cyclic AMP-independent casein kinase activity at 30 m...

journal_title：Gerontology

authors： Kumar R,Chiero L,Rodriguez D

更新日期：1984-01-01 00:00:00

abstract：:Aging is associated with a decline in renal concentrating ability in response to dehydration-induced arginine vasopressin (AVP) release. To examine target tissue sensitivity, cortical collecting tubules (CCT) were individually microdissected from young (3 months), middle-aged (2-3 years) and old (4-5.5 years) rabbits ...

journal_title：Gerontology

authors： Wilson PD,Dillingham MA

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To focus on diagnostic and therapeutic problems of pulmonary embolism in the elderly. METHODS:Retrospective analysis of 5 years of clinical, instrumental, and laboratory data (collected at the time of hospital admission) for patients 65 years and older with pulmonary embolism proven by a high-probability sci...

journal_title：Gerontology

authors： Masotti L,Ceccarelli E,Cappelli R,Guerrini M,Forconi S

更新日期：2000-07-01 00:00:00

abstract：:Prospective surveillance of nosocomial infection was conducted at seven skilled proprietary nursing facilities in Orange County, Calif., USA. The average incidence of facility-acquired infection was 5.2 infections/1,000 patient days. The most common source of infection was urinary tract (47%), followed by respiratory ...

journal_title：Gerontology

authors： Lee YL,Thrupp LD,Friis RH,Fine M,Maleki P,Cesario TC

更新日期：1992-01-01 00:00:00

abstract：:A brief review is given of the use of fluoride, mithramycin, glucagon, actinomycin D, calcitonins and diphosphonates for treatment of Paget's disease of bone. The decision regarding treatment, effectiveness of the drugs, the incidence of side effects and assessment of clinical, biochemical, histological, radiological ...

journal_title：Gerontology

authors： Chakravorty NK

更新日期：1979-01-01 00:00:00

abstract：:Induced tyrosine aminotransferase from adult and old rat liver was purified and its properties were studied. No differences could be detected for any physicochemical properties studied, i.e. specific activity, molecular weight, isoelectric point, thermostability, sensitivity to trypsin, Km for pyridoxal phosphate. Mor...

journal_title：Gerontology

authors： Szajnert MF,Schapira F

更新日期：1983-01-01 00:00:00

abstract：:Anaerobic bacteremia occurred in 68 patients over the age of 60 in a university hospital. These elderly patients were more likely than younger patients to have an underlying malignancy. Anaerobes involved included Bacteroides fragilis group (64 isolates), Bacteroides melaninogenicus group (11) and Clostridium species ...

journal_title：Gerontology

authors： Terpenning MS

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Older adults are stereotypically considered to be risk averse compared to younger age groups, although meta-analyses on age and the influence of gain/loss framing on risky choices have not found empirical evidence for age differences in risk-taking. OBJECTIVE:The current study extends the investigation of a...

journal_title：Gerontology

authors： Best R,Freund AM

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Many studies have demonstrated an inverse relationship between gait performance and cognitive impairment. The main purposes of this study were: (1) to design and validate a complex gait test (CGT) in older people, (2) to analyze the effects of age and sex on CGT, and (3) to analyze the association between CG...

journal_title：Gerontology

authors： Latorre Román PÁ,Muñoz Jiménez M,Salas Sánchez J,Consuegra González P,Moreno Del Castillo R,Herrador Sánchez JA,López Ivanco MDA,Linares Jiménez C,Navas Morales JF,Párraga Montilla JA

更新日期：2020-01-01 00:00:00

abstract：:The effect of centrophenixine has been studied on the monovalent electrolyte contents of the brain cortical cells of old female Wistar rats by means of energy dispersive x-ray microanalysis. The drug was administered in form of an intraperitoneal injection of 100 mg/kg body weight for 20 days. The treatment decreased ...

journal_title：Gerontology

authors： Zs-Nagy I,Pieri C,Giuli C,Del Moro M

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVES:Due to an increase in the percentage of older people in industrialized countries there is an increasing demand for medical care for the elderly. With advancing age, a series of structural, architectural and compositional modifications take place in the vasculature. Therefore, we analyzed the influence of pat...

journal_title：Gerontology

authors： Kröger K,Strubel G,Poser M,Pratikto T,Renzing-Köhler K,Rudofsky G

更新日期：2004-11-01 00:00:00

abstract：:Arterial aging is a cornerstone of organismal aging. The central arterial wall structurally and functionally remodels under chronic proinflammatory stress over a lifetime. The low-grade proinflammation that accompanies advancing age causes arterial wall thickening and stiffening. These structural and functional altera...

journal_title：Gerontology

authors： Wang M,Monticone RE,Lakatta EG

更新日期：2014-01-01 00:00:00

abstract：:Fishes exhibit a 'determinate' type of growth in short-lived species of warmer regions and an 'indeterminate' type in long-lived species of colder regions. Growth is measured in units of length and weight and is best represented as the specific growth rate. The relationship between weight and length provides an index ...

journal_title：Gerontology

authors： Dutta H

更新日期：1994-01-01 00:00:00

abstract：:The distribution of sister chromatid exchange (SCE) points has been analyzed in cultured lymphocytes from three age-groups of 30 females (n = 10; young: 13-20, middle-aged: 30-55, old: 75-84 years). The observed interchromosomal SCE distribution is in good agreement with the results of previous workers, significant ag...

journal_title：Gerontology

authors： Vormittag W

更新日期：1983-01-01 00:00:00

abstract：:The hippocampus is a structure equipped with a high degree of flexibility and adaptation. In contrast to most structures of the adult central nervous system, the hippocampus can rely on a form of plasticity known as neurogenesis. The continuous provision of new neurons derived from resident adult neural stem cells app...

journal_title：Gerontology

authors： Couillard-Despres S,Iglseder B,Aigner L

更新日期：2011-01-01 00:00:00