Predictors of improvement or decline in instrumental activities of daily living among community-dwelling older Japanese.

abstract：:Electrolytes and/or amino acids were determined in leg skeletal muscle biopsies from elderly (age range 57-75 years) and young (age range 20-35 years) apparently healthy women. When compared to the young group, the elderly one was characterized by increased levels of muscular Na+ and Cl-, while the calculated intracel...

journal_title：Gerontology

authors： Möller P,Alvestrand A,Bergström J,Fürst P,Hellström K

更新日期：1983-01-01 00:00:00

abstract：:Older adults have surprisingly high levels of well-being, which has been referred to as a paradox in the past. Improved emotion regulation has been suggested to underlie these high levels of well-being. Later life is also a period with enhanced exposure to critical life events, and this comes with risks. During such t...

journal_title：Gerontology

authors： Brose A,Ebner-Priemer UW

更新日期：2015-01-01 00:00:00

abstract：:Antinuclear antibodies, anticardiolipin antibodies and IgM rheumatoid factor were determined in 300 healthy aged subjects, comparing their prevalence to that in 100 healthy subjects aged between 19 and 44 years and 352 patients under 65 years of age, affected by various systemic rheumatic diseases. Increased productio...

journal_title：Gerontology

authors： Ruffatti A,Rossi L,Calligaro A,Del Ross T,Lagni M,Marson P,Todesco S

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Falls are a major cause of morbidity among older people. Multifaceted interventions may be effective in preventing falls and related fractures. OBJECTIVE:To evaluate the cost-effectiveness alongside the REducing Falls with Orthoses and a Multifaceted podiatry intervention (REFORM) trial. METHODS:REFORM was...

journal_title：Gerontology

authors： Corbacho B,Cockayne S,Fairhurst C,Hewitt CE,Hicks K,Kenan AM,Lamb SE,MacIntosh C,Menz HB,Redmond AC,Rodgers S,Scantlebury A,Watson J,Torgerson DJ,on behalf of the REFORM study.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The perioperative assessment and management of elderly patients with hip fracture and significant aortic stenosis (AS) is an increasingly common clinical problem with little data available to guide perioperative management. OBJECTIVES:It was the aim of this study to examine the incidence of perioperative ev...

journal_title：Gerontology

authors： Leibowitz D,Rivkin G,Schiffman J,Rott D,Weiss AT,Mattan Y,Kandel L

更新日期：2009-01-01 00:00:00

abstract：:The age-related accumulation of lipopigments was determined in the adrenergic and nonadrenergic peripheral neurons of the rat using a microspectrofluorometric method and electron microscopy, 3-, 12- and 30-month-old rats were used. The rate of lipopigment accumulation was greater in nonadrenergic than adrenergic neuro...

journal_title：Gerontology

authors： Koistinaho J

更新日期：1986-01-01 00:00:00

abstract：:The experimental evidence is reviewed which bears on the theory that aging in mammalian cells may be related to a decline in the efficiency of normal DNA repair processes. Although the data are as yet fragmentary, they do suggest that there is an age-associated decline in the capacity of cells to perform at least cert...

journal_title：Gerontology

authors： Little JB

更新日期：1976-01-01 00:00:00

abstract：:Sarcopenia is a complex and multifactorial disease that includes a decrease in the number, structure and physiology of muscle fibers, and age-related muscle mass loss, and is associated with loss of strength, increased frailty, and increased risk for fractures and falls. Treatment options are suboptimal and consist of...

journal_title：Gerontology

authors： Naranjo JD,Dziki JL,Badylak SF

更新日期：2017-01-01 00:00:00

abstract：:Cell surface of chick fibroblasts were labelled by a short treatment with 125I in presence of lactoperoxidase. A glycoprotein (220,000 molec. wt) was iodinated and was present in a more exposed position or in greater amounts at the surface of old phase III cells compared to young phase II cells. The findings extend ou...

journal_title：Gerontology

authors： Courtois Y,Hughes RC

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Many studies have demonstrated an inverse relationship between gait performance and cognitive impairment. The main purposes of this study were: (1) to design and validate a complex gait test (CGT) in older people, (2) to analyze the effects of age and sex on CGT, and (3) to analyze the association between CG...

journal_title：Gerontology

authors： Latorre Román PÁ,Muñoz Jiménez M,Salas Sánchez J,Consuegra González P,Moreno Del Castillo R,Herrador Sánchez JA,López Ivanco MDA,Linares Jiménez C,Navas Morales JF,Párraga Montilla JA

更新日期：2020-01-01 00:00:00

abstract：:Taurine (TAU) is thought to be a neuromodulator or an inhibitory neurotransmitter in the mammalian brain. In the periphery, TAU is involved in a wide spectrum of physiological functions. One of the most important putative physiological function of TAU is the modulation of cardiovascular activity including blood pressu...

journal_title：Gerontology

authors： Wallace DR,Dawson R Jr

更新日期：1990-01-01 00:00:00

abstract：:One of the problems associated with using random-source dogs to study in vivo vascular responses is their unknown background. Since aging is known to influence vascular responses, unknown variations in age could influence experimental results. The vast majority of aging studies examine arteries in vitro. This study wa...

journal_title：Gerontology

authors： Kaiser L,Ptu S

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Irrelevant unexpected stimuli elicit various types of inhibitory processes modulated by ongoing activity. An index of the inhibitory processes, namely the N2b and P3a event-related potentials (ERP), shows marked age-related differences. OBJECTIVE:In this experiment, we attempted to separate the effects of i...

journal_title：Gerontology

authors： Pató L,Czigler I

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Due to aging, tissue regeneration gradually declines. Contemporary strategies to promote tissue-specific regeneration, in particular in elderly patients, often include synthetic material apt for implantation primarily aiming at upholding body functions and regaining appropriate anatomical and functional inte...

journal_title：Gerontology

authors： Schimke MM,Paul S,Tillmann K,Lepperdinger G,Stigler RG

更新日期：2019-01-01 00:00:00

abstract：:A retrospective study was made of 50 consecutive cases of bacteraemia treated in a geriatric unit. The mortality rate was 24%, the highest incidence occurring amongst the cases of hospital-acquired bacteraemia where only 1 of 7 cases survived the infection. Pyrexia, acute confusion, and falls were the commonest presen...

journal_title：Gerontology

authors： Windsor AC

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Werner's syndrome, a rare autosomal recessive disorder, is characterized by features of premature aging. Seventy-five percent of the alleles of Japanese patients with Werner's syndrome have one of three major mutations. OBJECTIVE:To determine the genotype of a patient with Werner's syndrome. METHODS:We dia...

journal_title：Gerontology

authors： Nakayama T,Ochiai T,Takahashi Y,Ohkubo K,Hironaga T,Kokubun S

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:The link between longevity and diet is of great interest to biological and gerontological research. The fact that relevant knowledge has generally been available for many centuries is often not remarked upon. OBJECTIVE:This article examines three aspects of early modern Western medicine which thematize the ...

journal_title：Gerontology

authors： Schafer D

更新日期：2005-03-01 00:00:00

abstract：:We have previously shown that lymphocytes from Alzheimer's disease (AD) patients are hypersensitive to ionising radiation, as revealed by their higher levels of dicentrics than those from age-matched, normal individuals. We have now examined the sensitivity of these cells to N-methyl-N-nitrosourea or methyl methanesul...

journal_title：Gerontology

authors： Tobi SE,Neary D,Itzhaki RF

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Although cross-sectional studies have demonstrated associations between visual contrast sensitivity and cognitive test performance, it remains unclear whether peripheral visual or perceptual factors explain the association. OBJECTIVE:We aimed at determining whether reducing static contrast of the study stim...

journal_title：Gerontology

authors： Anstey KJ,Butterworth P,Borzycki M,Andrews S

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:C-reactive protein (CRP), a nonspecific marker of the inflammatory status, is associated with cardiovascular disease risk factors and may be an important feature of the metabolic syndrome (MSX) in middle-aged subjects. OBJECTIVES:We assessed the relationship of CRP levels to specific components of MSX and o...

journal_title：Gerontology

authors： Dupuy AM,Jaussent I,Lacroux A,Durant R,Cristol JP,Delcourt C

更新日期：2007-01-01 00:00:00

abstract：:Recently, Granacher et al. (2010) proposed an intergenerational approach to promoting balance and strength for fall prevention in children and elderly subjects together. Although this sounds like a stimulating idea, its effectiveness for fall prevention in both groups has yet to be demonstrated. Undoubtedly, fall prev...

journal_title：Gerontology

authors： Burtscher M,Kopp M

更新日期：2011-01-01 00:00:00

abstract：:We examined age- and diet-related alterations in RNA poly(A) tail length using high-resolution gel electrophoresis followed by Northern hybridization. The results demonstrate conclusively that there is no age-related decrease in the size of the Poly(A) tail of RNA isolated from the male Fischer 344 rat. In contrast, o...

journal_title：Gerontology

authors： Kristal BS,Conrad CC,Richarson A,Yu BP

更新日期：1993-01-01 00:00:00

abstract：:L-tryptophan (L-T) was added at a dose of 150-450 mg daily to eight Parkinsonian patients who developed visual hallucinations with paranoidal features under L-dopa (L-D) treatment (112.5-75 mg daily) in combination with alpha-methyldopa hydrazine (12.5-75 mg daily). In six patients L-T ameliorated the symptomatology b...

journal_title：Gerontology

authors： Rabey JM,Vardi J,Askenazi JJ,Streifler M

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:There is concern that people living in residential care in Australia make significant and often inappropriate use of acute in-patient hospital services. To date, no factual information has been collected in Australia and its absence may allow myths and negative stereotypes to proliferate. OBJECTIVE:To deter...

journal_title：Gerontology

authors： Finucane P,Wundke R,Whitehead C,Williamson L,Baggoley C

更新日期：2000-05-01 00:00:00

abstract：:Aging researchers have long been interested in understanding individuals' subjective perceptions of their own memory functioning. Previous research has shown that subjective memory ratings are partly based on memory performance but also reflect the influence of other factors, such as depressive symptoms. The aim of th...

journal_title：Gerontology

authors： Hülür G,Hertzog C,Pearman AM,Gerstorf D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Due to declining birthrates and an increasing aging population, shortage of the caregiving labor force has become a global issue. Among various efforts toward the solution, introducing robotic products for assistance could provide an effective way to help older adults in their daily lives. As previous studie...

journal_title：Gerontology

authors： Tu YC,Chien SE,Yeh SL

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) is a neurodegenerative disorder in middle and late age. Ribosomal RNA (rRNA) genes are located in the nucleolus (nucleolar organizer regions = NORs). There are increased deposits of beta-amyloid protein in the brains of the patients with AD and aged individuals with Down's syndrome (...

journal_title：Gerontology

authors： Dönmez-Altuntaş H,Akalin H,Karaman Y,Demirtaş H,Imamoğlu N,Ozkul Y

更新日期：2005-09-01 00:00:00

abstract：:Mechanisms underlying the decreased febrile response in the elderly have not been elucidated. One hypothesis is that elderly persons have a decreased response at the hypothalamic or peripheral effector level to endogenous pyrogen (EP). We studied the response to human monocyte-derived EP in young adult and aged Fische...

journal_title：Gerontology

authors： Tocco-Bradley R,Singer R,Kluger MJ,Kauffman CA

更新日期：1985-01-01 00:00:00

abstract：:Alzheimer neurofibrillary changes and senile plaques were found in a variety of distribution patterns and intensities in 50 brains of patients older than 73 years who had been carefully examined for signs of organic dementia in a geriatric unit. As noted by earlier observers, the severity of dementia usually correspon...

journal_title：Gerontology

authors： Ulrich J,Stähelin HB

更新日期：1984-01-01 00:00:00

abstract：:The glucose uptake of lizard brain slices decreased between young and middle-aged groups. There was a significant increase in the parameter between the middle-aged and old-age groups. Cold shock induced a decrease in glucose uptake of brain slices in the old, with no appreciable effect in the young and middle aged. ...

journal_title：Gerontology

authors： Dash BD,Patnaik BK

更新日期：1989-01-01 00:00:00