Protective Function of Ahnak1 in Vascular Healing after Wire Injury.

abstract：:In the present study, we investigated the actions of calmodulin (CaM) and CaM-dependent protein kinase II (CaMK-II) on the L-type Ca2+ currents (ICa(L)) of cultured vascular smooth muscle (VSM) cells (A7r5 cell line), using the whole-cell voltage clamp method. The peak IBa (Ca2+ channel using 5 mM Ba2+ as charge carri...

journal_title：Journal of vascular research

authors： Sunagawa M,Yokoshiki H,Seki T,Sperelakis N

更新日期：1998-09-01 00:00:00

abstract：:We investigated the possible interference of smooth muscle cells with monocyte response to LDL as well as with their adhesion and transmigration in a coculture of porcine endothelial and smooth muscle cells. Lysophosphatidylcholine (LPC), a component of oxidized LDL (oxLDL), stimulated the adhesion of THP-1 cells to e...

journal_title：Journal of vascular research

authors： Kinard F,Jaworski K,Sergent-Engelen T,Goldstein D,Van Veldhoven PP,Holvoet P,Trouet A,Schneider YJ,Remacle C

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND/AIMS:Laser Doppler flowmetry (LDF) was used to determine the influence of acute myocardial infarction (AMI) and of successful reperfusion treatment on basal skin blood flow and its oscillatory components. METHODS:Skin LDF was performed on all extremities in 58 patients 4-9 days after AMI (Killip class I), a...

journal_title：Journal of vascular research

authors： Azman-Juvan K,Bernjak A,Urbancic-Rovan V,Stefanovska A,Stajer D

更新日期：2008-01-01 00:00:00

abstract：:Vascular restenosis is one of the major concerns for the management of coronary artery disease using therapeutic vascular procedures. Treatments with thrombin-specific inhibitors, hirudin or hirulog-1, reduced ischemic events in coronary artery disease patients. Early started and prolonged infusions of these thrombin ...

journal_title：Journal of vascular research

authors： Xue M,Ren S,Welch S,Shen GX

更新日期：2001-03-01 00:00:00

abstract：:Signaling pathways activated by the tachykinin substance P (SP) were investigated in pig coronary artery endothelial cells (PCAECs). Single cells were obtained after enzymatic digestion of coronary arteries. Intracellular Ca2+ ([Ca2+]i) was measured from fura-2 fluorescence while membrane potential or ionic current wa...

journal_title：Journal of vascular research

authors： Davis MJ,Sharma NR

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:We have developed an in vitro model by organ culture of rat mesenteric arteries to imitate vascular smooth muscle cell (VSMC) receptor changes in cardiovascular disease. By using this model, alteration of VSMC thromboxane A(2) (TP) receptors was studied. METHODS AND RESULTS:After organ culture of the arteri...

journal_title：Journal of vascular research

authors： Zhang W,Zhang Y,Edvinsson L,Xu CB

更新日期：2009-01-01 00:00:00

abstract：:Most virus-infected cells release interferon-beta (IFN-beta) as a powerful inducer of antiviral defense. Endothelial cells tightly regulate local immune cell recruitment by expression of adhesion molecules and chemokines. Here, we studied the transcriptional regulation of IFN-beta-induced chemokine expression in prima...

journal_title：Journal of vascular research

authors： Buttmann M,Berberich-Siebelt F,Serfling E,Rieckmann P

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to evaluate different signaling pathways by which exercise training would interfere in endothelial function in obesity. Therefore, we examined adipocytokine levels and their receptors in the corpus cavernosum and femoral artery from trained rats on a high-fat diet. METHODS:F...

journal_title：Journal of vascular research

authors： Sponton AC,Silva FH,Araujo HN,Valgas da Silva CP,de Moraes C,Antunes E,Zanesco A,Delbin MA

更新日期：2017-01-01 00:00:00

abstract：:The purpose of the present study was to develop a rapid, reproducible method of nonviral gene transfer to the intact vasculature. Male Sprague-Dawley rats were anesthetized, a midline abdominal incision was made and segmental branches of the superior mesenteric artery were dissected free of surrounding mesentery. A sp...

journal_title：Journal of vascular research

authors： Martin JB,Young JL,Benoit JN,Dean DA

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:A new method was evaluated where local changes in oxygen tension were induced in a tissue while being studied under a microscope in vivo. We tested whether hypoxic vasodilation and hyperoxic vasoconstriction in arterioles in striated muscle are being propagated upstream, and whether the endothelium and smoot...

journal_title：Journal of vascular research

authors： Riemann M,Rai A,Ngo AT,Dziegiel MH,Holstein-Rathlou NH,Torp-Pedersen C

更新日期：2011-01-01 00:00:00

abstract：:Fibroblast growth factor-2 (FGF2) and vascular endothelial growth factor (VEGF) exert their angiogenic activity by interacting with endothelial cells in a distinct manner. In this study, we investigated the morphological features of endothelial cells of the chick embryo chorioallantoic membrane (CAM) microvasculature ...

journal_title：Journal of vascular research

authors： Ribatti D,Nico B,Morbidelli L,Donnini S,Ziche M,Vacca A,Roncali L,Presta M

更新日期：2001-07-01 00:00:00

abstract：:The mechanosensitive nonselective cation channel (NSC(MS)) is a key player in vascular myogenic contraction. The functional channel density and pressure sensitivity of NSC(MS) in vascular myocytes were compared between pulmonary and systemic arteries (coronary, mesenteric and cerebral arteries) in the rabbit. In cell-...

journal_title：Journal of vascular research

authors： Park KS,Lee HA,Earm KH,Ko JH,Earm YE,Kim SJ

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIMS:Dysfunction of endothelial progenitor cell (EPCs) contributes to diabetic vascular disease. We reported that downregulated miR-126 in diabetic patients causes EPC dysfunction. The study was designed to investigate how high glucose (HG) and advanced glycation end products (AGEs) regulate miR-126 expressi...

journal_title：Journal of vascular research

authors： Li Y,Zhou Q,Pei C,Liu B,Li M,Fang L,Sun Y,Li Y,Meng S

更新日期：2016-01-01 00:00:00

abstract：:The aim of this study was to use periarterial manipulation to produce an atheroma-like neo-intima in rabbits and study resting blood flow and vascular responsiveness in vivo. One common carotid artery was enclosed in a silastic collar to induce a neo-intima similar to that of human early atherosclerosis, and carotid b...

journal_title：Journal of vascular research

authors： Arthur JF,Dusting GJ,Woodman OL

更新日期：1994-07-01 00:00:00

abstract：:Increased vascular disease occurs with low albumin (human serum albumin, HSA), possibly reflecting specific inhibition of endothelial apoptosis reported for tissue culture. Despite the reported specificity for endothelial protection by HSA, the high but physiological concentrations needed appear more consistent with n...

journal_title：Journal of vascular research

authors： Bolitho C,Bayl P,Hou JY,Lynch G,Hassel AJ,Wall AJ,Zoellner H

更新日期：2007-01-01 00:00:00

abstract：:In response to stimuli, endothelial cells release arachidonic acid, a lipid precursor of various vasoactive substances. We have investigated the relationships between cytosolic Ca2+ movements and arachidonic acid release in human umbilical vein endothelial cells. Histamine, a receptor-dependent agonist, and thapsigarg...

journal_title：Journal of vascular research

authors： Millanvoye-Van Brussel E,David-Dufilho M,Pham TD,Iouzalen L,Aude Devynck M

更新日期：1999-05-01 00:00:00

abstract：:The novel endothelial cell tyrosine kinase receptors, Tie1 and Tie2, are essential for vascular development and remodeling in the embryo but little is known regarding the regulation of their expression and their role in the maintenance and repair of the adult vascular system. We examined the expression of Tie1 and Tie...

journal_title：Journal of vascular research

authors： Fujikawa K,Presman E,Isner JM,Varticovski L

更新日期：1999-07-01 00:00:00

abstract：:Conduit arteries of hypertensive rats are thicker and stiffer than those of normotensive controls. The possible role played by collagen type I and II subtypes in the mechanism of arterial stiffness remains unknown. The carotid and aortic arterial wall of rats of Japanese (Wistar-Kyoto and spontaneously hypertensive ra...

journal_title：Journal of vascular research

authors： Chamiot Clerc P,Renaud JF,Blacher J,Legrand M,Samuel JL,Levy BI,Sassard J,Safar ME

更新日期：1999-03-01 00:00:00

abstract：:The D allele of the insertion (I)/deletion (D) polymorphism in the angiotensin-converting enzyme (ACE) gene and the C allele of the A1166-C polymorphism in the angiotensin II type 1 receptor (AGT1R) gene have been associated with altered vascular structure and with an increased risk of myocardial infarction. The aim o...

journal_title：Journal of vascular research

authors： Steeds RP,Toole LO,Channer KS,Morice AH

更新日期：1999-11-01 00:00:00

abstract：:Inflammation is a highly regulated process with common but also specific characteristics in each tissue affected. Recruitment of leukocytes from the blood to the injured tissue is an important early step in the inflammatory cascade. This review highlights the role of connexins (Cxs) in the regulation of both acute and...

journal_title：Journal of vascular research

authors： Scheckenbach KE,Crespin S,Kwak BR,Chanson M

更新日期：2011-01-01 00:00:00

abstract：:A radioligand binding assay and autoradiographic localisation of P2X-purinoceptors were carried out in several different blood vessels from rat, guinea-pig and rabbit by using [3H]alpha,beta-methylene ATP ([3H]alpha,beta-MeATP) as the radioligand. The radioligand binding assay on rabbit ear artery showed that the bind...

journal_title：Journal of vascular research

authors： Bo X,Burnstock G

更新日期：1993-03-01 00:00:00

abstract：:The goal of this study was to determine the role of endothelium-derived relaxing factor (EDRF) in dilatation of cerebral arterioles in response to adenosine 5'-diphosphate (ADP). Using intravital microscopy, we measured the diameters of pial arterioles in vivo in rats during superfusion with ADP, acetylcholine and nit...

journal_title：Journal of vascular research

authors： Mayhan WG

更新日期：1992-09-01 00:00:00

abstract：:Although the content of histamine in myocardial tissue is high, its contribution to the regulation of coronary blood flow has not been clearly defined. The aim of the present study was to investigate whether or not nitric oxide (NO), an important modulator of coronary vascular tone, is involved in histamine-induced co...

journal_title：Journal of vascular research

authors： Kelm M,Feelisch M,Krebber T,Motz W,Strauer BE

更新日期：1993-05-01 00:00:00

abstract：:The effects of the close arterial infusion of histamine upon the microcirculation of facial and nasal tissues were examined in dogs. Blood flow through arteriovenous anastomoses (AVA flow), capillaries (CAP flow) and collaterals (COL flow) were determined by electromagnetic flowmetry and the tracer-microsphere techniq...

journal_title：Journal of vascular research

authors： Bari F,Ariwodola JO,Pleschka K

更新日期：1993-01-01 00:00:00

abstract：:Previous studies have demonstrated endothelial and smooth muscle hyperplasia occur during arterial luminal expansion associated with elevation of arterial wall shear rates. The current study investigated whether remodeling induced by elevated wall shear would ultimately result in a vessel with intimal and medial cell ...

journal_title：Journal of vascular research

authors： Fath SW,Burkhart HM,Miller SC,Dalsing MC,Unthank JL

更新日期：1998-07-01 00:00:00

abstract：:The aim of this study was to verify that subcutaneous lymph node transplantation inducing lymphatic regeneration is possible in healthy adult rats, in analogy to results obtained in other species. This rat model was used to determine the effects of lymph node fragmentation as well as sheep erythrocytes and platelet-ri...

journal_title：Journal of vascular research

authors： Hadamitzky C,Blum KS,Pabst R

更新日期：2009-01-01 00:00:00

abstract：UNLABELLED:Diabetic patients have an increased risk of restenosis and late stent thrombosis after angioplasty, i.e. complications that are related to a defective re-endothelialization. Exendin-4, a stable glucagon-like peptide (GLP)-1 receptor agonist, has been suggested to influence the formation of intimal hyperplasi...

journal_title：Journal of vascular research

authors： Eriksson L,Saxelin R,Röhl S,Roy J,Caidahl K,Nyström T,Hedin U,Razuvaev A

更新日期：2015-01-01 00:00:00

abstract：AIMS:Percutaneous coronary intervention is routinely performed to treat occlusive coronary artery disease. Coronary perforation is a potential complication and can be treated with a stent graft. Current stent grafts are associated with high restenosis rates. We tested the safety and feasibility of biodegradable stent g...

journal_title：Journal of vascular research

authors： Taavitsainen J,Tarvainen S,Kuivanen A,Mangiardi EK,Guelcher M,Martin J,Mathur A,Hytönen JP,Ylä-Herttuala S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Low birth weight (LBW) is associated with increased risk of type 2 diabetes and cardiovascular disease. We studied endothelial function and insulin sensitivity in young men with LBW (n = 22) and controls (n = 22). METHODS:Insulin sensitivity and endothelial function was studied with venous occlusion plethys...

journal_title：Journal of vascular research

authors： Sonne MP,Højbjerre L,Alibegovic AC,Vaag A,Stallknecht B,Dela F

更新日期：2010-01-01 00:00:00

abstract：:In segments of rabbit basilar artery (BA) platelet-activating factor (PAF) initiated a concentration-dependent transitory contraction which was unaffected by indomethacin or nordihydroguaiaretic acid (NDGA). N omega-nitro-L-arginine (NLA) did not change the magnitude of PAF-induced contraction, but in the presence of ...

journal_title：Journal of vascular research

authors： Akopov SE,Sercombe R,Seylaz J

更新日期：1995-01-01 00:00:00