Autoimmune hemolytic anemia associated with the use of immune checkpoint inhibitors for cancer: 68 cases from the Food and Drug Administration database and review.

abstract：OBJECTIVES:Northern Norway consists of a multiethnic population of Sámi and non-Sámi. We evaluated iron status in these two groups with respect to gender, age and residence. METHODS:In 2002-2004, a cross-sectional study of health and living conditions in areas with both Sámi and Norwegian populations, SAMINOR, was per...

journal_title：European journal of haematology

authors： Broderstad AR,Melhus M,Lund E

更新日期：2007-11-01 00:00:00

abstract：:Many cost analyses of stem-cell transplantations are available, which is in sharp contrast to the level of cost analyses on first-line chemotherapy for aggressive non-Hodgkin's lymphoma (NHL). Given the scarcity of cost analyses of first-line chemotherapy for NHL, it is difficult to assess the economic impact of upcom...

journal_title：European journal of haematology

authors： van Agthoven M,Faber LM,Uyl-de Groot CA,Sonneveld P,Verdonck LF,Willemze R,Kluin-Nelemans JC,Löwenberg B,Huijgens PC

更新日期：2002-10-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection is one of the most common causes of morbidity and mortality after allogeneic marrow transplantation. We studied 14 consecutive CMV-seropositive patients adding ganciclovir (2.5 mg/kg i.v. every 8 hours for 7 days prior to transplant and 6 mg/kg three times a week after neutrophils becam...

journal_title：European journal of haematology

authors： Yau JC,Dimopoulos MA,Huan SD,Tarrand JJ,Spencer V,Spitzer G,Meneghetti CM,Wallerstein RO,Andersson BS,LeMaistre CF

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Tumor lysis syndrome (TLS) is a complication that can cause renal failure by precipitation of uric acid (UA) and phosphate crystals in renal tubules. Rasburicase proved to be effective in rapidly reducing UA levels. Costs of rasburicase average up to 4500 euros. To assess if lower doses of rasburicase are ef...

journal_title：European journal of haematology

authors： Hummel M,Reiter S,Adam K,Hehlmann R,Buchheidt D

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:Interactions between hemopoietic cells and the stromal microenvironment or immunoreactive cells are mediated by specific cell surface receptors. The expression of those molecules may alter the adhesive qualities (mobility and homing) as well as immune response behavior of leukemic blasts. L-Selectin (CD62L) ...

journal_title：European journal of haematology

authors： Graf M,Reif S,Hecht K,Pelka-Fleischer R,Pfister K,Nuessler V,Schmetzer H

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Haemorrhagic cystitis caused by BK virus (BKV) is a known complication of allogeneic haematopoietic cell transplantation (HCT) and is relatively common following HLA-haploidentical transplantation. Adoptive immunotransfer of virus-specific T cells from the donor is a promising therapeutic approach, although ...

journal_title：European journal of haematology

authors： Pello OM,Innes AJ,Bradshaw A,Finn SA,Uddin S,Bray E,Olavarria E,Apperley JF,Pavlů J

更新日期：2017-06-01 00:00:00

abstract：:The heat production rate in peripheral blood lymphocytes was evaluated by direct calorimetry in 76 untreated adults with non-Hodgkin's lymphoma (NHL). Elevated values were recorded for 20 out of 54 patients with lymphomas of high or intermediate malignancy grade (37%) and for 1 out of 22 patients (5%) with low grade l...

journal_title：European journal of haematology

authors： Monti M,Brandt L,Ikomi-Kumm J,Olsson H

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVES:Granulocyte colony-stimulating factor-mobilized peripheral blood hematopoietic stem cell transplantation (HSCT) provides a valuable and increasingly used alternative to bone marrow transplantation (BMT). This retrospective study aimed at determining whether the stem cell source is predictive for outcome, rel...

journal_title：European journal of haematology

authors： Auberger J,Clausen J,Kircher B,Kropshofer G,Lindner B,Nachbaur D

更新日期：2011-12-01 00:00:00

abstract：:A murine cultured cell line (MKM-O) was established from a tumor of a BALB/C (nu/nu) mouse that had been subcutaneously inoculated with human hepatoma tissue fragments in the same location. The MKM-O cell line was proven to be of endothelial origin by morphological examinations and positive staining with fluorescein-l...

journal_title：European journal of haematology

authors： Yoshimura T,Miyanomae T,Tanaka M,Iwai Y,Mayumi M,Mikawa H

更新日期：1987-08-01 00:00:00

abstract：:In addition to BCR, various rare fusion partners for the ABL1 gene have been reported in leukemia. We have identified the fusion gene SNX2-ABL1 in a pediatric case of acute lymphoblastic leukemia (ALL), which has only once previously been reported in an adult patient. Cytogenetic analysis detected this fusion gene ari...

journal_title：European journal of haematology

authors： Masuzawa A,Kiyotani C,Osumi T,Shioda Y,Iijima K,Tomita O,Nakabayashi K,Oboki K,Yasuda K,Sakamoto H,Ichikawa H,Hata K,Yoshida T,Matsumoto K,Kiyokawa N,Mori T

更新日期：2014-03-01 00:00:00

abstract：:Interferon (IFN) is one of several drugs effective in treating multiple myeloma (MM), and propagermanium is an IFN inducer. We report on 10 MM patients who were treated with propagermanium at doses from 10 to 40 mg. Two patients achieved complete remission (CR), two patients achieved partial remission (PR), and the co...

journal_title：European journal of haematology

authors： Tsutsumi Y,Tanaka J,Kanamori H,Musashi M,Minami H,Fukushima A,Yamato H,Ehira N,Kawamura T,Obara S,Ogura N,Asaka M,Imamura M,Masauzi N

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVES:Disseminated adenovirus (AdV) infections following allogeneic stem cell transplantation (allo-SCT) are increasingly recognised, particularly in children. This study evaluated the clinical relevance of disseminated AdV infections in adult allo-SCT recipients, after different conditioning regimens. METHODS:In...

journal_title：European journal of haematology

authors： Kalpoe JS,van der Heiden PL,Barge RM,Houtzager S,Lankester AC,van Tol MJ,Kroes AC

更新日期：2007-04-01 00:00:00

abstract：:Acute myelogenous leukemia with t(8;21)(q22;q22) developed in a 42-yr-old woman having thrombocytopenia with absent radii syndrome (TARS). Standard induction and postremission therapies were safely administered. With each successive chemotherapy, the onset of platelet recovery was not delayed, but peak platelet counts...

journal_title：European journal of haematology

authors： Go RS,Johnston KL

更新日期：2003-04-01 00:00:00

abstract：:The presence of CD25 and HC2 antigens in 66 different patients with acute myeloid leukemia (AML) was investigated. The expression of both antigens was observed in 32% of AML cells. Dual fluorescence staining experiments performed in 5 AML patient cells showed that CD25 and HC2 antigens were simultaneously expressed in...

journal_title：European journal of haematology

authors： Padrós MR,Salamone MC,Zunszain PA,Fainboim L

更新日期：1989-05-01 00:00:00

abstract：:Reduced-intensity conditioning regimens have demonstrated lower toxicity but increased relapse rates in the context of allogeneic hematopoietic stem cell transplantation (aSCT) for patients with acute myelogenous leukemia (AML). The FLAMSA- reduced-intensity conditioning (RIC) regimen, combining a cytoreductive and a ...

journal_title：European journal of haematology

authors： Holtick U,Shimabukuro-Vornhagen A,Chakupurakal G,Theurich S,Leitzke S,Burst A,Hallek M,von Bergwelt-Baildon M,Scheid C,Chemnitz JM

更新日期：2016-05-01 00:00:00

abstract：:Intravascular lymphoma (IVL) is a rare type of extranodal lymphoma in which the lymphoma cells proliferate exclusively in lumina of small vessels. Here, we report a clinicopathological study of 13 cases IVL diagnosed at our institution between March 1999 and July 2007, and evaluated the clinical characteristics, usefu...

journal_title：European journal of haematology

authors： Matsue K,Asada N,Takeuchi M,Yamakura M,Kimura S,Odawara J,Aoki T

更新日期：2008-03-01 00:00:00

abstract：INTRODUCTION:Outcome of patients with standard-risk (SR) multiple myeloma (MM) has improved; however, subsets of patients do worse than expected. We sought to identify the factors associated with inferior outcome. METHODS:We evaluated 51 patients with SR MM that received upfront autologous hematopoietic stem cell tran...

journal_title：European journal of haematology

authors： Badar T,Srour S,Bashir Q,Shah N,Al-Atrash G,Hosing C,Popat U,Nieto Y,Orlowski RZ,Champlin R,Qazilbash MH

更新日期：2017-03-01 00:00:00

abstract：:We tested the immunosuppressive effect of cord blood (CB) natural killer (NK) cells using highly purified CB NK cells in mixed lymphocyte cultures (MLC) containing autologous CB T cells as responders. Control cultures were done without NK cells. Our findings revealed that CB NK cells induced a dose-dependent inhibitio...

journal_title：European journal of haematology

authors： El Marsafy S,Dosquet C,Coudert MC,Bensussan A,Carosella E,Gluckman E

更新日期：2001-04-01 00:00:00

abstract：:Our aim was to assess liver iron content, in thalassaemic patients, by using three different MR protocols and compare their data. Ninety-four thalassaemic patients (44 M and 50 F, mean age 25.82 +/- 8.3 yrs), were enrolled in the study. In each patient, three measurements of the liver iron content were performed, with...

journal_title：European journal of haematology

authors： Christoforidis A,Perifanis V,Spanos G,Vlachaki E,Economou M,Tsatra I,Athanassiou-Metaxa M

更新日期：2009-05-01 00:00:00

abstract：INTRODUCTION:Prenatal diagnosis of severe alpha- and beta-thalasssemia diseases is usually performed by DNA analysis. OBJECTIVE:To establish a simple method, we have evaluated the reliability of prenatal diagnosis by fetal blood analysis using automated capillary electrophoresis system. METHODS:Forty-seven fetal bloo...

journal_title：European journal of haematology

authors： Srivorakun H,Fucharoen G,Sae-Ung N,Sanchaisuriya K,Ratanasiri T,Fucharoen S

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:Transfusional iron overload is of major concern in hematological disease. Iron-overload-related dyserythropoiesis and reactive oxygen species (ROS)-related damage to hematopoietic stem cell (HSC) function are major setbacks in treatment for such disorders. We therefore aim to investigate the effect of iron o...

journal_title：European journal of haematology

authors： Lu W,Zhao M,Rajbhandary S,Xie F,Chai X,Mu J,Meng J,Liu Y,Jiang Y,Xu X,Meng A

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Interleukin-6 (IL-6) is a multifunctional cytokine that plays roles in the immune response, inflammation and hematopoiesis. Serum IL-6 levels have reported to reflect disease severity and high tumor burden in multiple myeloma (MM) patients and to correlate with several other laboratory parameters. Serum-solu...

journal_title：European journal of haematology

authors： Hatzimichael EC,Christou L,Bai M,Kolios G,Kefala L,Bourantas KL

更新日期：2001-01-01 00:00:00

abstract：:Neonatal alloimmune thrombocytopenia (NAIT) occurs because of transplacentally acquired maternal platelet alloantibodies. Most of the alloantibodies are against human platelet antigens, but the alloantibody against CD36 is rare. A full-term female baby was delivered by a mother who experienced two spontaneous abortion...

journal_title：European journal of haematology

authors： Taketani T,Ito K,Mishima S,Kanai R,Uchiyama A,Hirata Y,Kumakura S,Ishikura H,Yamaguchi S

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Non-Hodgkin lymphoma patients have a 25% increased risk of secondary primary neoplasms (SPNs). Regarding the controversy about the increased risk of SPN in patients exposed to radioimmunotherapy (RIT), we have analyzed this issue in a cohort of follicular lymphoma (FL) patients treated with/without RIT. PAT...

journal_title：European journal of haematology

authors： Andrade-Campos MM,Liévano P,Espinosa-Lara N,Soro-Alcubierre G,Grasa-Ulrich JM,López-Gómez L,Baringo T,Giraldo P

更新日期：2016-12-01 00:00:00

abstract：:The therapeutic management of patients with idiopathic hemochromatosis (IH) requires an accurate estimate of hepatic iron overload in order to prevent tissue fibrosis and organ failure. Magnetic resonance imaging (MRI) was used to estimate liver iron overload in 5 patients with IH and in 8 normal controls. Signal inte...

journal_title：European journal of haematology

authors： Andersen PB,Birgegård G,Nyman R,Hemmingsson A

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVE:Diagnosing myeloid sarcoma remains challenging, and we aimed to provide clinicopathological features to facilitate diagnosis. METHOD:Clinicopathological data from 41 patients with de novo and 31 with secondary myeloid sarcoma were reviewed. RESULTS:Most de novo cases presented with isolated myeloid sarcoma ...

journal_title：European journal of haematology

authors： Claerhout H,Van Aelst S,Melis C,Tousseyn T,Gheysens O,Vandenberghe P,Dierickx D,Boeckx N

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:Hepcidin, a peptide hormone released by hepatocytes into circulation is the main regulator of dietary iron absorption and cellular iron release. Although commercial tests are available, assay harmonization for hepcidin has not been yet reached, making reference intervals and consequent clinical decisions sti...

journal_title：European journal of haematology

authors： Cangemi G,Pistorio A,Miano M,Gattorno M,Acquila M,Bicocchi MP,Gastaldi R,Riccardi F,Gatti C,Fioredda F,Calvillo M,Melioli G,Martini A,Dufour C

更新日期：2013-04-01 00:00:00

abstract：:Thirty-four patients with myelodysplastic syndromes, 23 men and 11 women, aged between 47 and 80 years, with all types of myelodysplastic syndromes were treated with 13-cis-retinoic acid. The dose of retinoic acid ranged between 10 and 60 mg/m2/daily and was administered in combination with vitamin E to diminish side ...

journal_title：European journal of haematology

authors： Bourantas KL,Tsiara S,Christou L

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to compare the major transplant outcomes between patients receiving hematopoietic stem cell transplantation (HSCT) from bone marrow (BM) or peripheral blood stem cells (PBSC). METHODS:All consecutive HSCT patients using BM or PBSC from an HLA-matched related donors for haemat...

journal_title：European journal of haematology

authors： Campregher PV,Hamerschlak N,Colturato VA,Mauad MA,de Souza MP,Bouzas LF,Tavares Rde C,Barros JC,Chiattone R,Paz A,Silla L,Vigorito AC,Miranda E,Funke VA,Flowers ME

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To correlate the clinical and hematological features of β-globin gene haplotypes with the oxidative stress status in pediatric patients with sickle cell disease (SCD). METHODS:A total of 95 patients with SCD and 40 healthy children were studied. The β-globin cluster, plasma lipid peroxidation (LPO) and plasm...

journal_title：European journal of haematology

authors： Rusanova I,Escames G,Cossio G,de Borace RG,Moreno B,Chahboune M,López LC,Díez T,Acuña-Castroviejo D

更新日期：2010-12-01 00:00:00