Abstract：
BACKGROUND:Limited data exist on bioresorbable scaffolds (BRS) in patients with acute coronary syndrome (ACS). The aim of the present study was to evaluate novolimus-eluting BRS (DESolve) as interventional treatment for patients with ACS, and to compare its 12-month outcomes with the everolimus-eluting bioresorbable scaffolds (Absorb). METHODS:In this retrospective study, patients with ACS (including unstable angina pectoris, ST-segment elevation myocardial infarction, or non-ST-segment elevation myocardial infarction) treated with either the Absorb or the DESolve BRS were evaluated in a 1:1 matched-pair analysis. Major adverse cardiac events (MACE), including death, myocardial infarction, and target lesion revascularization, were evaluated as a major endpoint. The occurrence of scaffold thrombosis was also assessed. RESULTS:A total of 102 patients were eligible for this analysis. The rate of MACE at 12 months was comparable between the Absorb and the DESolve group (8.3% vs. 6.8%, p = 0.738). The occurrence of target lesion revascularization (6.2% vs. 4.7%; p = 0.700) and scaffold thrombosis (4.1% vs. 2.1%; p = 0.580) was comparable as well. All instances of scaffold thrombosis occurred within 30 days of the index procedure. CONCLUSION:In this study, similar 12-month event rates were observed for both BRS types after implantation for the treatment of ACS.
journal_name
Herzjournal_title
Herzauthors
Nef HM,Wiebe J,Schmidt G,Möllmann H,Boeder NF,Dörr O,Bauer T,Blachutzik F,Liebetrau C,Elsässer A,Foin N,Hamm CWdoi
10.1007/s00059-019-4822-7subject
Has Abstractpub_date
2020-12-01 00:00:00pages
95-104issue
Suppl 1eissn
0340-9937issn
1615-6692pii
10.1007/s00059-019-4822-7journal_volume
45pub_type
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