Abstract:
:Cardiovascular diseases are the leading cause of death worldwide. Adherence to a healthy lifestyle lifelong is capable of significantly reducing the cardiovascular risk by up to 70% and is therefore a key component in primary prevention of cardiovascular disease. According to the European and American guidelines lifestyle interventions include not smoking, daily physical activity of ≥150 min/week at moderate intensity or 75 min/week for higher intensity physical activity, a cardioprotective nutrition (high proportion of unsaturated fatty acids, low amounts of saturated fatty acids and low salt intake), normal body weight (body mass index 20-25 kg/m2), arterial blood pressure <140/90 mm Hg (optimum <130/80 mm Hg), low-density lipoprotein (LDL)-cholesterol target values depending on the cardiovascular risk and a normal glucose metabolism in type 2 diabetes mellitus with adjustment of a HbA1c to <7%. Lifestyle measures with weight reduction and intensification of physical activity can improve the cardiometabolic risk factors. In this way reduction of the systolic and diastolic blood pressures by approximately 10-15 mm Hg, reduction of HbA1c by approximately 1 % and reduction of triglycerides by ca. 30-40 % are possible. The LDL-cholesterol and lipoprotein(a) levels cannot be easily influenced. Beyond the recommendations for a cardioprotective lifestyle, additional pharmacological therapy may have to be added depending on the cardiovascular risk profile.
journal_name
Herzjournal_title
Herzauthors
Heinicke V,Halle Mdoi
10.1007/s00059-019-04886-ysubject
Has Abstractpub_date
2020-02-01 00:00:00pages
30-38issue
1eissn
0340-9937issn
1615-6692pii
10.1007/s00059-019-04886-yjournal_volume
45pub_type
杂志文章,评审相关文献
HERZ文献大全abstract:BACKGROUND:The German national guidelines on chronic heart failure provide treatment recommendations to physicians and reflect the current level of evidence; however, it is questionable to what extent these recommendations are applied in the routine practice and what the effect of guideline adherence on mortality is. ...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-016-4401-0
更新日期:2016-11-01 00:00:00
abstract::47 patients with aortic valve disease were studied by left ventricular micromanometry and cineangiography before and 18 months after successful valve replacement. There were 27 patients (17 with aortic stenosis, ten with aortic insufficiency) with moderate hypertrophy (angiographic mass less than 180 g/m2) and 20 pati...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1984-10-01 00:00:00
abstract::Geminin, a key regulator of DNA replication licensing in the cell cycle, plays an essential role in determining the fate of cells via suppression of cell proliferation and cellular differentiation. Neuropeptide Y (NPY) intensifies the proliferation of vascular smooth muscle cells (VSMCs) directly by binding with Y1 re...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-018-4721-3
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Atrial remodeling in the form of fibrosis is considered the basis in the development of atrial fibrillation (AF). The aim of this study was to investigate the effects of doxycycline on atrial remodeling induced by chronic intermittent hypoxia (CIH) and the mechanisms underlying such changes. METHODS:A total...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-018-4768-1
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Renal denervation (RDN) has been proposed as a novel antihypertensive intervention for treating resistant hypertension. It remains to be investigated which patient groups can potentially benefit from RDN. The present study aimed to evaluate the efficacy and safety of RDN in patients with mild-moderate resist...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-017-4664-0
更新日期:2019-08-01 00:00:00
abstract::The standardized and constant fixed-dose rate, no necessity for a close and regular blood monitoring as well as the small number of interactions with other drugs and daily food make therapy with the new oral anticoagulants dabigatran and rivaroxaban and in future presumably apixaban much easier and more feasible than ...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-012-3619-8
更新日期:2012-06-01 00:00:00
abstract::In a medical out-patient clinic, over a period of several years, atrial myxoma was diagnosed in four patients with ages ranging between 32 and 69 years. With the exception of one patient referred for assessment of ventricular premature beats, presentation was not primarily attributable to cardiac causes. In all patien...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract::An electrophysiological study (EPS) and a programmed ventricular stimulation (PVS) are strongly recommended and clearly indicated before the implantation of a cardioverter defibrillator (ICD), if patients present with a cardiac arrest and no structural heart disease or a hypertrophic cardiomyopathy. In these patients ...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-005-2671-z
更新日期:2005-03-01 00:00:00
abstract:OBJECTS:To show all cardiac evaluations multislice computed tomography (MSCT) can perform. METHODS:MSCTs were performed on an MSCT scanner (Mx8000; Philips Medical Systems) with enhanced contrast acquisition. The reconstructed images were sent to a workstation for multiplanar reconstruction, volume rendering, and 3-D ...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-003-2443-6
更新日期:2003-02-01 00:00:00
abstract::Atrial fibrillation represents the most common form of clinical arrhythmia in daily routine. However, current therapeutic options are still limited and a better understanding of the underlying molecular mechanisms is expected to contribute to the development of new therapeutic strategies. The scientific field of micro...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-012-3594-0
更新日期:2012-03-01 00:00:00
abstract::Unexplained sudden death in the young is cardiovascular in most cases. Structural and conduction defects in cardiac-related genes can conspire to underlie sudden cardiac death. Here we report a clinical investigation and an extensive genetic assessment of a Tunisian family with sudden cardiac death in young members. I...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-019-04883-1
更新日期:2020-01-22 00:00:00
abstract::Over the past decade there has been a steady proliferation of indices which have been proposed for assessing ventricular function. Many of these indices are based on single measurements and often are insensitive and have limited clinical utility. The present article focuses on the role of wall stress in assessing vent...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1981-10-01 00:00:00
abstract::As a result of an aging, increasingly obese, and decreasingly physically active population, the global incidence and prevalence of type 2 diabetes mellitus (DM) is increasing. While little can be done to influence the contribution of aging to the increasing global prevalence of diabetes, opportunities abound to develo...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-004-2605-1
更新日期:2004-08-01 00:00:00
abstract::Venous disease of the lower extremities comprises several common conditions such as varicose veins, superficial thrombophlebitis, deep venous thrombosis and chronic venous insufficiency. The high prevalence and increasing incidence with age of these disorders impose relevant diagnostic and therapeutic concerns. Varico...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-007-2958-3
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Causes of pericardial effusion requiring pericardiocentesis are very complex; a summary of 140 patients, especially those having iatrogenic pericardial effusion, is rare. METHODS:We prospectively analyzed the clinical data and etiology of moderate to large pericardial effusion requiring pericardiocentesis a...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-011-3428-5
更新日期:2012-03-01 00:00:00
abstract::During the last decade, epigenetics became one of the fastest growing research fields in numerous clinical and basic science disciplines. Evidence suggests that chromatin modifications (e.g., histone modifications and DNA methylation) as well as the expression of micro-RNA molecules play a crucial role in the pathogen...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-015-4213-7
更新日期:2015-05-01 00:00:00
abstract::Familial dilated cardiomyopathy (F-DCM) describes a clinically and genetically heterogeneous group of diseases, mostly inherited as autosomal dominant traits, having idiopathic left ventricular dilatation and dysfunction as a common phenotype. The age of onset, rate of progression, disease complications, as well as ov...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-012-3707-9
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:Cardiovascular magnetic resonance imaging (CMR) has been established as a modality to detect myocardial viability. The aim of this study was to evaluate myocardial viability by observing transmural extent of infraction and microvascular perfusion level. METHODS:We performed CMR in 30 myocardial infarction (M...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-018-4741-z
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND AND AIM OF THE STUDY:The predisposition to atrial fibrillation (AF) in mitral stenosis (MS) has been demonstrated with several electrocardiographic (increased P-wave dispersion) and echocardiographic parameters (atrial electromechanical delay). Despite the improvement in P-wave dispersion after percutaneous ...
journal_title:Herz
pub_type: 临床试验,杂志文章
doi:10.1007/s00059-012-3672-3
更新日期:2013-03-01 00:00:00
abstract::Numerous angiographic control regression studies have demonstrated that aggressive reduction of plasma cholesterol significantly reduces the incidence of clinical overt cardiovascular complications, but has almost no effect on the angiographically determined luminal diameter of the coronary arteries. These, as well as...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/BF03043815
更新日期:1999-02-01 00:00:00
abstract::Disorders of the autonomic nervous control mechanisms of heart rate and vascular tone may cause syncope. Notably these are carotid sinus and vasovagal syndromes. Knowledge of their aetiology is limited. Each presents cardioinhibition and vasodepression. Pacing offers benefit in cardioinhibition and the mode required i...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1993-06-01 00:00:00
abstract::Genetic testing plays an increasing role in cardiovascular medicine. Advances in technology and the development of novel and more affordable (high throughput) methods have led to the identification of genetic risk factors in research and clinical practice. Also, this progress has simplified the screening of patients a...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-017-4576-z
更新日期:2017-08-01 00:00:00
abstract:UNLABELLED:Due to the increasing number of elderly as well as chronically-ill patients, venous thrombosis assumes an increasing role as a typical complication of many courses of disease. Postoperatively, in patients without anticoagulation, fibrinogen tests show venous thrombosis in the lower extremities in up to 50% b...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1989-12-01 00:00:00
abstract::Routine determination of troponin levels is recommended for all patients with acute ischemic stroke. In 20-55% of these patients the troponin levels are elevated, which may be caused by ischemic as well as non-ischemic myocardial damage and particularly neurocardiogenic myocardial damage. In patients with acute ischem...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-020-04967-3
更新日期:2020-07-06 00:00:00
abstract::Transcatheter procedures have been adopted as novel treatment strategy for patients with valvular heart disease, particularly for those who are inoperable or at high risk for surgical valve procedures. Significant technological advances have resulted in an improvement of devices for transcatheter aortic valve replacem...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-015-4207-5
更新日期:2015-04-01 00:00:00
abstract::The European Society of Cardiology (ESC) has recently published new guidelines on the diagnosis and management of chronic coronary syndromes (CCS). Due to variable symptoms, objective tests are often necessary to confirm the diagnosis, exclude alternative diagnoses, and assess the severity of underlying disease. This ...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-020-04935-x
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Unstable angina accounts for more than one million hospital admissions annually. 6-8% of patients with this condition have non-fatal myocardial infarction or die within the first year after diagnosis. Recently, the term "acute coronary syndromes" has been used to describe the spectrum of conditions that incl...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/pl00002018
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was the analysis of long-term results in patients with hemodynamically significant mitral valve disease due to extensively calcified mitral annulus who underwent decalcification and patch reconstruction. PATIENTS AND METHODS:Between 1996 and 2008 a total of 109 patients underwent surger...
journal_title:Herz
pub_type: 临床试验,杂志文章
doi:10.1007/s00059-011-3576-7
更新日期:2012-11-01 00:00:00
abstract::Adequate skin perfusion is one of the most important prerequisites for healing of trophic lesions and amputation wounds in patients with peripheral arterial disease. The discrepancies possible between macro- and microcirculations stress the necessity of new methods for assessment of terminal vascular beds. With laser-...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1988-12-01 00:00:00
abstract::The term "chest pain with normal coronary arteries" encompasses a large number of different cardiac pathophysiological abnormalities, including impairment of coronary flow reserve, endothelial dysfunction, and early atherosclerosis that, in most cases, cannot be readily differentiated one from the other. To study earl...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-005-2659-8
更新日期:2005-02-01 00:00:00