Medical Management of Endometriosis in Patients with Chronic Pelvic Pain.

Abstract:

:Endometriosis is a common cause of pelvic pain in women of reproductive age. Traditional medical therapies are hormonal in nature, including estrogen-progestin contraceptives, progestins, and gonadotropin-releasing hormone (GnRH) agonists. Other hormonal options are androgens and aromatase inhibitors, with research also suggesting a possible role for GnRH antagonists and selective progesterone receptor modulators. Other than nonsteroidal anti-inflammatories, further work is required for nonhormonal therapies such as antiangiogenic and immune-modulating drugs. Medical treatment of endometriosis can be complex, and requires consideration of side effects, the anatomic type of endometriosis, role of surgery, current infertility or future fertility desires, and other contributors to pain (e.g., central sensitization). These factors should be discussed for each patient, to ensure personalized treatment and optimal outcomes.

journal_name

Semin Reprod Med

authors

Bedaiwy MA,Allaire C,Yong P,Alfaraj S

doi

10.1055/s-0036-1597308

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

38-53

issue

1

eissn

1526-8004

issn

1526-4564

journal_volume

35

pub_type

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