Abstract:
PURPOSE OF REVIEW:Fractures of osteoporotic bone in elderly individuals need special attention. This manuscript reviews the current strategies to provide sufficient fracture fixation stability with a particular focus on fractures that frequently occur in elderly individuals with osteoporosis and require full load-bearing capacity, i.e., pelvis, hip, ankle, and peri-implant fractures. RECENT FINDINGS:Elderly individuals benefit immensely from immediate mobilization after fracture and thus require stable fracture fixation that allows immediate post-operative weight-bearing. However, osteoporotic bone has decreased holding capacity for metallic implants and is thus associated with a considerable fracture fixation failure rate both short term and long term. Modern implant technologies with dedicated modifications provide sufficient mechanical stability to allow immediate weight-bearing for elderly individuals. Depending on fracture location and fracture severity, various options are available to reinforce or augment standard fracture fixation systems. Correct application of the basic principles of fracture fixation and the use of modern implant technologies enables mechanically stable fracture fixation that allows early weight-bearing and results in timely fracture healing even in patients with osteoporosis.
journal_name
Curr Osteoporos Repjournal_title
Current osteoporosis reportsauthors
Hollensteiner M,Sandriesser S,Bliven E,von Rüden C,Augat Pdoi
10.1007/s11914-019-00535-9subject
Has Abstractpub_date
2019-12-01 00:00:00pages
363-374issue
6eissn
1544-1873issn
1544-2241pii
10.1007/s11914-019-00535-9journal_volume
17pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:The goal of this paper is to review state-of-the-art transcriptome profiling methods and their recent applications in the field of skeletal biology. RECENT FINDINGS:Next-generation sequencing of mRNA (RNA-seq) methods have been established and routinely used in skeletal biology research. RNA-seq has ...
journal_title:Current osteoporosis reports
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doi:10.1007/s11914-019-00517-x
更新日期:2019-08-01 00:00:00
abstract:PURPOSE OF REVIEW:One aim in bone tissue engineering is to develop human cell-based, 3D in vitro bone models to study bone physiology and pathology. Due to the heterogeneity of cells among patients, patient's own cells are needed to be obtained, ideally, from one single cell source. This review attempts to identify the...
journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
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更新日期:2021-01-15 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-019-00524-y
更新日期:2019-10-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章
doi:10.1007/s11914-009-0011-6
更新日期:2009-07-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
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更新日期:2017-08-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-020-00652-w
更新日期:2021-01-07 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
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更新日期:2015-04-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-013-0157-0
更新日期:2013-09-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-012-0125-0
更新日期:2012-12-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
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更新日期:2014-06-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
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更新日期:2020-12-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-013-0152-5
更新日期:2013-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To identify the use of carbon nanomaterials in bone regeneration and present new data on the regenerative capacity of bone tissue in osteopenic rats treated with graphene nanoribbons (GNRs). RECENT FINDINGS:The results show that the physical and chemical properties of the nanomaterials are suitable f...
journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-018-0476-2
更新日期:2018-10-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-018-0450-z
更新日期:2018-08-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-005-0018-6
更新日期:2005-09-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-019-00545-7
更新日期:2019-12-01 00:00:00
abstract:PURPOSE OF REVIEW:In addition to the actions of the endocrine hormone, 1alpha,25-dihydroxyvitamin D (1,25(OH)2D) in stimulating intestinal calcium absorption, the regulation of bone mineral metabolism by 1,25(OH)2D is also considered an important contributor to calcium homeostasis. However, recent evidence suggest that...
journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-017-0394-8
更新日期:2017-10-01 00:00:00
abstract::Caloric restriction caused by undernutrition or over-exercise is increasingly common and has significant health consequences such as hypothalamic amenorrhea, infertility, attainment of low peak bone mass, and bone loss leading to fracture. In these patients, the pathophysiology of amenorrhea and bone loss is multifact...
journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-007-0011-3
更新日期:2007-12-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-018-0446-8
更新日期:2018-08-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-010-0023-2
更新日期:2010-09-01 00:00:00
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更新日期:2017-08-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11914-011-0068-x
更新日期:2011-12-01 00:00:00
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更新日期:2010-09-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 已发布勘误
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更新日期:2020-10-29 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章
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更新日期:2013-12-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
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更新日期:2007-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-12-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
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更新日期:2016-10-01 00:00:00
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journal_title:Current osteoporosis reports
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更新日期:2004-03-01 00:00:00
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journal_title:Current osteoporosis reports
pub_type: 杂志文章,评审
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更新日期:2020-02-01 00:00:00