abstract：Purpose:BRCA1/2 mutations are associated with risks of breast and ovarian cancer. In Korea, incidences of BRCA1/2 genetic testing and risk-reducing surgery (RRS) have increased with insurance coverage and the Angelina Jolie effect. The aim of this study was to identify trends in RRS performed in Korean women with the B...

journal_title：Journal of breast cancer

authors： Jung SM,Ryu JM,Park HS,Park JS,Kang E,Lee S,Lee HB,Youn HJ,Yoo TK,Kim J,Lee JE,Han SA,Kim D,Kim SW,Korean Hereditary Breast Cancer Study Group.

更新日期：2020-12-03 00:00:00

abstract：:The combination of luteinizing hormone-releasing hormone analogs (LHRHa) with tamoxifen is used as a standard postoperative adjuvant therapy in patients with hormone receptor-positive/premenopausal breast cancer. Long-acting LHRHa formulations offer advantages in terms of patient convenience. However, data on the effe...

journal_title：Journal of breast cancer

authors： Lee YJ,Wu ZY,Kim HJ,Lee JW,Chung IY,Kim J,Lee SB,Son BH,Kim SB,Jung JH,Gong G,Ahn SH,Ko B

更新日期：2020-10-26 00:00:00

abstract：Purpose:Breast cancer treatments, including chemotherapy, administered in combination with glucocorticoids can induce hyperglycemia. This study aimed to investigate the effect of hyperglycemia during adjuvant chemotherapy on the prognosis of breast cancer patients without a known history of diabetes. Methods:In this s...

journal_title：Journal of breast cancer

authors： Ahn HR,Kang SY,Youn HJ,Jung SH

更新日期：2020-08-05 00:00:00

abstract：Purpose:We aimed to investigate the clinicopathologic factors associated with distant metastasis (DM) and post-recurrence overall survival (OS) after salvage treatments for isolated locoregional recurrence (ILRR) of breast cancer and identify long-term surviving patients for providing a more personalized therapy. Meth...

journal_title：Journal of breast cancer

authors： Kim BH,Shin KH,Chie EK,Kim JH,Kim K,Hwang KT,Kim J,Choi IS,Park JH,Kim S

更新日期：2020-04-29 00:00:00

abstract：Purpose:The 8th edition of the American Joint Committee on Cancer (AJCC) staging manual introduced a new prognostic staging system for breast cancer. This study aimed to evaluate the changes in staging distribution and predictive power of the new staging system. Methods:Of the 12,275 patients with breast cancer identi...

journal_title：Journal of breast cancer

authors： Kim EJ,Park HS,Kim JY,Kim SI,Cho YU,Park BW

更新日期：2020-01-09 00:00:00

abstract：:ESR1 mutation is frequently encountered in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC), especially after aromatase inhibitor (AI) therapy, as a mechanism of resistance to endocrine therapy. Circulating tumor DNA-based detection of ESR1 mutatio...

journal_title：Journal of breast cancer

authors： Carausu M,Melaabi S,Pierga JY,Bidard FC,Cabel L

更新日期：2019-12-19 00:00:00

abstract：Purpose:Triple-negative breast cancer (TNBC) is associated with poor prognosis with limited treatment options. Angiogenesis is known to be involved in the progression of TNBC, and targeting this pathway results in modest clinical benefits. In this study, we analyzed the role of tumor microvascular endothelial Notch1 (E...

journal_title：Journal of breast cancer

authors： Kim D,Lee J,Kang J,Kim SH,Yoo TK,Oh S,Lee A

更新日期：2019-12-12 00:00:00

abstract：:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis belong to a severe dermatopathic spectrum that includes frequently fatal mucocutaneous manifestations consisting of whole epidermal necrosis and sloughing with bullous transformation, blistering, and further skin detachment. Notably, cancer patients are at ...

journal_title：Journal of breast cancer

authors： López-Gómez V,Yarza R,Muñoz-González H,Revilla E,Enrech S,González-Valle O,Tolosa P,Ciruelos E

更新日期：2019-09-18 00:00:00

abstract：Purpose:This study was aimed at identifying the influence of initial weight and weight change during neoadjuvant chemotherapy (NAC) on pathologic complete response (pCR) and long-term survival in Chinese patients with operable breast cancer. Methods:We conducted a retrospective study using data from 409 female patient...

journal_title：Journal of breast cancer

authors： Fang Q,Huang J,Gan L,Shen K,Chen X,Wu B

更新日期：2019-08-26 00:00:00

abstract：Purpose:The benefit of post-mastectomy radiation therapy (PMRT) in patients with breast cancer who achieve ypN0 following neoadjuvant chemotherapy (NAC) has not yet been established. This study aimed to identify the role of PMRT in patients who achieve ypN0 according to molecular subtype. Methods:We identified patient...

journal_title：Journal of breast cancer

authors： Cho WK,Park W,Choi DH,Kim YB,Kim JH,Kim SS,Kim K,Kim JH,Ahn SJ,Lee SY,Lee J,Kim SW,Kwon J,Ahn KJ

更新日期：2019-05-13 00:00:00

abstract：:Oxygen is crucial to maintain the homeostasis in aerobic cells. Hypoxia is a condition in which cells are deprived of the oxygen supply necessary for their optimum performance. Whereas oxygen deprivation may occur in normal physiological processes, hypoxia is frequently associated with pathological conditions. It has ...

journal_title：Journal of breast cancer

authors： Daimiel I

更新日期：2019-05-13 00:00:00

abstract：Purpose:Pokemon, also known as ZBTB7A, belongs to the POZ and Krüppel (POK) family of transcription repressors and is implicated in tumor progression as a key proto-oncogene. This present study aimed at determining the mechanism by which Pokemon inhibits transforming growth factor β (TGFβ)-Smad4 pathway-dependent proli...

journal_title：Journal of breast cancer

authors： Chen L,Zhong J,Liu JH,Liao DF,Shen YY,Zhong XL,Xiao X,Ding WJ,Peng XD,Xiong W,Zu XY

更新日期：2019-02-15 00:00:00

abstract：:When faced with a case of bilateral breast cancer (BBC), understanding how to differentiate bilateral primary breast cancer from contralateral metastatic breast cancer is essential for treatment, but clear identification criteria have not been established to date. Diverse events play different roles in the therapy and...

journal_title：Journal of breast cancer

authors： Li X,Yang M,Zhang Q,Fan Y,Zhu T,Chen F,Wang K

更新日期：2019-02-02 00:00:00

abstract：Purpose:The aim of this study was to investigate the association of telomere length with breast cancer risk. We simultaneously explored the association between telomerase reverse transcriptase gene polymorphisms and telomere length. Methods:We used real-time quantitative polymerase chain reaction to measure relative t...

journal_title：Journal of breast cancer

authors： Wang Z,Zhang Z,Guo Y,Shui H,Liu G,Jin T,Wang H

更新日期：2018-12-01 00:00:00

abstract：Purpose:Previous oncological studies showed that lymph node ratio (LNR) (ratio of number of lymph nodes that tested positive for metastasis to the total number of lymph nodes examined) is a negative indicator of cancer survival. The American Joint Committee on Cancer (AJCC) staging system incorporates tumor size, lymph...

journal_title：Journal of breast cancer

authors： Hung M,Xu J,Nielson D,Bounsanga J,Gu Y,Hansen AR,Voss MW

更新日期：2018-09-01 00:00:00

abstract：:Apocrine encapsulated papillary carcinoma (EPC) of the breast is a rare neoplasm, and only 10 cases have been reported in the literature to date. Although EPC by definition lacks a peripheral myoepithelial layer, all previously published apocrine EPC cases were clinically indolent and lacked a conventional invasive co...

journal_title：Journal of breast cancer

authors： Kővári B,Ormándi K,Simonka Z,Vörös A,Cserni G

更新日期：2018-06-01 00:00:00

abstract：Purpose:The treatment of triple-negative breast cancer (TNBC) remains challenging, due to the absence of estrogen, progesterone, and human epidermal growth factor receptors. This study was designed to evaluate the efficiency and safety of cytokine-induced killer (CIK) cell immunotherapy, following regular chemotherapy,...

journal_title：Journal of breast cancer

authors： Li M,Wang Y,Wei F,An X,Zhang N,Cao S,Ren B,Zhang X,Ren X

更新日期：2018-06-01 00:00:00

abstract：:Malignant melanoma rarely originates from the female nipple. Tumors that develop on the skin of the breast are often subject to a delayed diagnosis. Cytologic examination provides excellent diagnostic capabilities and is a safe procedure with a lower risk of local implantation, compared to needle or incisional biopsy....

journal_title：Journal of breast cancer

authors： Nagata Y,Yoshioka M,Uramoto H,Tsurudome Y,Yamada S,Hanagiri T,Tanaka F

更新日期：2018-03-01 00:00:00

abstract：Purpose:The exact mechanism regulating fibronectin (FN) expression in breast cancer cells has not been fully elucidated. In this study, we investigated the pharmacological mechanism of berberine (BBR) with respect to FN expression in triple-negative breast cancer (TNBC) cells. Methods:The clinical significance of FN m...

journal_title：Journal of breast cancer

authors： Jeong Y,You D,Kang HG,Yu J,Kim SW,Nam SJ,Lee JE,Kim S

更新日期：2018-03-01 00:00:00

abstract：Purpose:Whether tamoxifen affects the risk of neurodegenerative disease is controversial. This nationwide population-based study investigated the risk of Parkinson's disease (PD) associated with tamoxifen treatment in female patients with breast cancer using Taiwan's National Health Insurance Research Database. Method...

journal_title：Journal of breast cancer

authors： Hong CT,Chan L,Hu CJ,Lin CM,Hsu CY,Lin MC

更新日期：2017-12-01 00:00:00

abstract：:[This corrects the article on p. 192 in vol. 20, PMID: 28690656.]. ...

journal_title：Journal of breast cancer

authors： Chu AJ,Chang JM,Cho N,Moon WK

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:The MammaPrint™ gene signature, currently used in clinical practice, provides prognostic information regarding the recurrence and potential metastasis in breast cancer patients. However, the prognostic information of the 70 genes included can only be estimated at the RNA expression level. In this study, we inve...

journal_title：Journal of breast cancer

authors： Fatima A,Tariq F,Malik MFA,Qasim M,Haq F

更新日期：2017-09-01 00:00:00

abstract：:The median time of brain metastasis from the diagnosis of breast cancer is approximately 3 years. In this case report, a 69-year-old woman demonstrated cerebellar ataxia. Brain magnetic resonance imaging revealed enhanced lesions in bilateral cerebellar hemispheres. She had undergone surgery, radiation, and chemothera...

journal_title：Journal of breast cancer

authors： Yamada SM,Tomita Y,Shibui S,Kurokawa T,Baba Y

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:Metastasis and local recurrence are the primary causes of treatment failure and patient death in breast cancer. The aim of this study was to validate a metastasis- and local recurrenceassociated biomarker for prognostic evaluation and planning treatment strategies. METHODS:Formalin-fixed, paraffin-embedded tis...

journal_title：Journal of breast cancer

authors： Ye F,Zhong X,Qiu Y,Yang L,Wei B,Zhang Z,Bu H

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:Breast volume assessment is one of the most important steps during implant-based breast reconstruction because it is critical in selecting implant size. According to previous studies, there is a close relationship between the mastectomy specimen weight and resected breast volume. The aim of this study was to ev...

journal_title：Journal of breast cancer

authors： Baek WY,Byun IH,Kim YS,Lew DH,Jeong J,Roh TS

更新日期：2017-03-01 00:00:00

abstract：:Internationally, breast cancer is the most common female cancer, and is induced by a combination of environmental, genetic, and epigenetic risk factors. Despite the advancement of imaging techniques, invasive sampling of breast epithelial cells is the only definitive diagnostic procedure for patients with breast cance...

journal_title：Journal of breast cancer

authors： Cheuk IW,Shin VY,Kwong A

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:Surgical clips are used as a target for postoperative breast radiotherapy, and displacement of surgical clips would result in inaccurate delivery of radiation. We investigated the displacement range of surgical clips in the breast during postoperative radiotherapy following breast-conserving surgery. METHODS:A...

journal_title：Journal of breast cancer

authors： Sung S,Lee JH,Lee JH,Kim SH,Kwak YK,Lee SW,Jeon YW,Suh YJ

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:This study assessed the incidence and cancer rate of probably benign lesions detected on bilateral whole-breast screening ultrasound (US), which corresponded to US Breast Imaging Reporting and Data System (BI-RADS) category 3, and evaluated the proper management of those lesions. METHODS:This study was approve...

journal_title：Journal of breast cancer

authors： Nam SY,Ko EY,Han BK,Shin JH,Ko ES,Hahn SY

更新日期：2016-09-01 00:00:00

abstract：:The prognosis associated with brain metastasis arising from breast cancer is very poor. Eribulin is a microtubule dynamic inhibitor synthesized from halichondrin B, a natural marine product. In a phase III study (EMBRACE), eribulin improved overall survival in patients with heavily pretreated metastatic breast cancers...

journal_title：Journal of breast cancer

authors： Byun KD,Ahn SG,Baik HJ,Lee A,Bae KB,An MS,Kim KH,Shin JH,Park HK,Cho H,Jeong J,Kim TH

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:MicroRNAs (miRNAs) are a major class of small endogenous RNA molecules that posttranscriptionally regulate the expression of most genes in the human genome. miRNAs are often located in chromosomal fragile sites, which are suscept-ible to amplification or deletion. Chromosomal deletions are frequent events in br...

journal_title：Journal of breast cancer

authors： Damavandi Z,Torkashvand S,Vasei M,Soltani BM,Tavallaei M,Mowla SJ

更新日期：2016-06-01 00:00:00

abstract：:The Korean Breast Cancer Society (KBCS) has reported a nationwide breast cancer data since 1996. We present a comprehensive report on the facts and trends of breast cancer in Korea in 2013. Data on the newly diagnosed patients in the year 2013 were collected from 99 hospitals by using nationwide questionnaire survey. ...

journal_title：Journal of breast cancer

authors： Min SY,Kim Z,Hur MH,Yoon CS,Park EH,Jung KW,Korean Breast Cancer Society Consortium.

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:Somatic mutations of the chromatin remodeling AT-rich interactive domain 1A (SWI-like) gene (ARID1A) have been identified in many human cancers, including breast cancer. The purpose of this study was to evaluate the nuclear expression of ARID1A in breast cancers by immunohistochemistry (IHC) and to correlate th...

journal_title：Journal of breast cancer

authors： Cho HD,Lee JE,Jung HY,Oh MH,Lee JH,Jang SH,Kim KJ,Han SW,Kim SY,Kim HJ,Bae SB,Lee HJ

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:The purpose of this study was to assess the incidence of invasive lobular carcinoma (ILC) and to compare the clinicopathological features and treatment results after breast conserving surgery (BCS) followed by radiotherapy between ILC and invasive ductal carcinoma (IDC). METHODS:A total of 1,071 patients who u...

journal_title：Journal of breast cancer

authors： Park JS,Choi DH,Huh SJ,Park W,Kim YI,Nam SJ,Lee JE,Kil WH

更新日期：2015-09-01 00:00:00

abstract：:Breast cancer generally develops in older women and its incidence is continuing to increase with increasing age of the population. The pathology and biology of breast cancer seem to be different in the elderly, often resulting in the undertreatment of elderly patients and thus in higher rates of recurrence and mortal-...

journal_title：Journal of breast cancer

authors： Dimitrakopoulos FI,Kottorou A,Antonacopoulou AG,Makatsoris T,Kalofonos HP

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:Breast cancer subtype correlates with response to systemic therapy and overall survival (OS), but its impact on lymphatic spread is incompletely understood. In this study, we used the Surveillance, Epidemiology, and End Results registry to assess whether the subtype can predict the presence of nodal metastasis ...

journal_title：Journal of breast cancer

authors： Mattes MD,Bhatia JK,Metzger D,Ashamalla H,Katsoulakis E

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:We investigated the feasibility of using surgical clips as markers for tumor localization and their effect on the imaging evaluation of treatment responses after neoadjuvant chemotherapy (NAC). METHODS:A total of 16 breast cancers confirmed by needle biopsy in 15 patients were included in this study from Octob...

journal_title：Journal of breast cancer

authors： Youn I,Choi SH,Kook SH,Choi YJ,Park CH,Park YL,Kim DH

更新日期：2015-03-01 00:00:00

abstract：:Multiple symmetric lipomatosis (MSL), or Madelung's disease, is a rare disease of unknown etiology. It is characterized by the presence of loose adipose tissue deposits localized in the cervical region and upper body. MSL presenting as bilateral huge gynecomastia is an extremely rare phenomenon. The present report des...

journal_title：Journal of breast cancer

authors： Jang JH,Lee A,Han SA,Ryu JK,Song JY

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel belonging to the transient receptor potential family, and it is expressed in different neoplastic tissues. Its activation is associated with regulation of cancer growth and progression. The aim of this research was to study the ex...

journal_title：Journal of breast cancer

authors： Vercelli C,Barbero R,Cuniberti B,Racca S,Abbadessa G,Piccione F,Re G

更新日期：2014-12-01 00:00:00

abstract：:Since recurrent bilateral breast infection due to nontuberculous mycobacterium (NTM) is rare, its diagnosis is easily overlooked; in addition, complete recovery is often difficult to achieve. We report a case of recurrent bilateral infection in a 35-year-old woman who had completed treatment for NTM. Although various ...

journal_title：Journal of breast cancer

authors： Yoo H,Choi SH,Kim YJ,Kim SJ,Cho YU,Choi SJ

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:The Gail model is one of the most widely used tools to assess the risk of breast cancer. However, it is known to overestimate breast cancer risk for Asian women. Here, we validate the Gail model and the Korean model using Korean data, and subsequently update and revalidate the Korean model using recent data. M...

journal_title：Journal of breast cancer

authors： Min JW,Chang MC,Lee HK,Hur MH,Noh DY,Yoon JH,Jung Y,Yang JH,Korean Breast Cancer Society.

更新日期：2014-09-01 00:00:00