Detection of Methylated Circulating DNA as Noninvasive Biomarkers for Breast Cancer Diagnosis.

abstract：:The combination of luteinizing hormone-releasing hormone analogs (LHRHa) with tamoxifen is used as a standard postoperative adjuvant therapy in patients with hormone receptor-positive/premenopausal breast cancer. Long-acting LHRHa formulations offer advantages in terms of patient convenience. However, data on the effe...

journal_title：Journal of breast cancer

authors： Lee YJ,Wu ZY,Kim HJ,Lee JW,Chung IY,Kim J,Lee SB,Son BH,Kim SB,Jung JH,Gong G,Ahn SH,Ko B

更新日期：2020-10-26 00:00:00

abstract：PURPOSE:The objective of this study was to describe the evolution of health-related quality of life (HRQOL) in a cohort of breast cancer patients over 1 year after surgery and to analyse the predictive ability of HRQOL measurement instruments. METHODS:Observational, multicenter and prospective study of a cohort of bre...

journal_title：Journal of breast cancer

authors： Moro-Valdezate D,Peiró S,Buch-Villa E,Caballero-Gárate A,Morales-Monsalve MD,Martínez-Agulló A,Checa-Ayet F,Ortega-Serrano J

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:We investigated the relationship between BRCA mutations and the distribution of familial cancers other than breast or ovary in high-risk breast cancer patients. METHODS:PATIENTS WITH BREAST CANCER WHO HAD AT LEAST ONE OF THE FOLLOWING RISK FACTORS WERE ENROLLED: reported family history of breast or ovarian can...

journal_title：Journal of breast cancer

authors： Noh JM,Choi DH,Baek H,Nam SJ,Lee JE,Kim JW,Ki CS,Park W,Huh SJ

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:Breast cancer subtype correlates with response to systemic therapy and overall survival (OS), but its impact on lymphatic spread is incompletely understood. In this study, we used the Surveillance, Epidemiology, and End Results registry to assess whether the subtype can predict the presence of nodal metastasis ...

journal_title：Journal of breast cancer

authors： Mattes MD,Bhatia JK,Metzger D,Ashamalla H,Katsoulakis E

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:We evaluated the effect of local recurrence (LR) and regional recurrence (RR) on distant metastasis and survival in patients treated with breast conservation therapy (BCT). METHODS:We analyzed 907 patients who were treated for invasive breast cancer between 1993 and 2006. With 53 months of follow-up, 28 patien...

journal_title：Journal of breast cancer

authors： Lee JS,Kim SI,Park HS,Lee JS,Park S,Park BW

更新日期：2011-09-01 00:00:00

abstract：:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis belong to a severe dermatopathic spectrum that includes frequently fatal mucocutaneous manifestations consisting of whole epidermal necrosis and sloughing with bullous transformation, blistering, and further skin detachment. Notably, cancer patients are at ...

journal_title：Journal of breast cancer

authors： López-Gómez V,Yarza R,Muñoz-González H,Revilla E,Enrech S,González-Valle O,Tolosa P,Ciruelos E

更新日期：2019-09-18 00:00:00

abstract：:The median time of brain metastasis from the diagnosis of breast cancer is approximately 3 years. In this case report, a 69-year-old woman demonstrated cerebellar ataxia. Brain magnetic resonance imaging revealed enhanced lesions in bilateral cerebellar hemispheres. She had undergone surgery, radiation, and chemothera...

journal_title：Journal of breast cancer

authors： Yamada SM,Tomita Y,Shibui S,Kurokawa T,Baba Y

更新日期：2017-06-01 00:00:00

abstract：Purpose:The treatment of triple-negative breast cancer (TNBC) remains challenging, due to the absence of estrogen, progesterone, and human epidermal growth factor receptors. This study was designed to evaluate the efficiency and safety of cytokine-induced killer (CIK) cell immunotherapy, following regular chemotherapy,...

journal_title：Journal of breast cancer

authors： Li M,Wang Y,Wei F,An X,Zhang N,Cao S,Ren B,Zhang X,Ren X

更新日期：2018-06-01 00:00:00

abstract：Purpose:Whether tamoxifen affects the risk of neurodegenerative disease is controversial. This nationwide population-based study investigated the risk of Parkinson's disease (PD) associated with tamoxifen treatment in female patients with breast cancer using Taiwan's National Health Insurance Research Database. Method...

journal_title：Journal of breast cancer

authors： Hong CT,Chan L,Hu CJ,Lin CM,Hsu CY,Lin MC

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:The purpose of this study was to assess the incidence of invasive lobular carcinoma (ILC) and to compare the clinicopathological features and treatment results after breast conserving surgery (BCS) followed by radiotherapy between ILC and invasive ductal carcinoma (IDC). METHODS:A total of 1,071 patients who u...

journal_title：Journal of breast cancer

authors： Park JS,Choi DH,Huh SJ,Park W,Kim YI,Nam SJ,Lee JE,Kil WH

更新日期：2015-09-01 00:00:00

abstract：Purpose:Triple-negative breast cancer (TNBC) is associated with poor prognosis with limited treatment options. Angiogenesis is known to be involved in the progression of TNBC, and targeting this pathway results in modest clinical benefits. In this study, we analyzed the role of tumor microvascular endothelial Notch1 (E...

journal_title：Journal of breast cancer

authors： Kim D,Lee J,Kang J,Kim SH,Yoo TK,Oh S,Lee A

更新日期：2019-12-12 00:00:00

abstract：PURPOSE:In our previous studies we showed that upregulating claudin-6 (CLDN6) expression may contribute to preventing breast cancer, and that 17β-estradiol induces a concentration- and time-related effect on CLDN6 mRNA and protein expression in MCF-7 cells. However, the mechanisms of 17β-estradiol regulation of CLDN6 a...

journal_title：Journal of breast cancer

authors： Yafang L,Qiong W,Yue R,Xiaoming X,Lina Y,Mingzi Z,Ting Z,Yulin L,Chengshi Q

更新日期：2011-03-01 00:00:00

abstract：:Breast cancer is the most common malignancy, and it is also the major cause of cancer-related deaths of women worldwide. Breast cancer treatment involves surgery, chemotherapy, radiation therapy, or combination therapy, and novel strategies are needed to boost the oncologic outcome. The non-metabolizable glucose analo...

journal_title：Journal of breast cancer

authors： Aghaee F,Pirayesh Islamian J,Baradaran B

更新日期：2012-06-01 00:00:00

abstract：:ESR1 mutation is frequently encountered in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC), especially after aromatase inhibitor (AI) therapy, as a mechanism of resistance to endocrine therapy. Circulating tumor DNA-based detection of ESR1 mutatio...

journal_title：Journal of breast cancer

authors： Carausu M,Melaabi S,Pierga JY,Bidard FC,Cabel L

更新日期：2019-12-19 00:00:00

abstract：:On a pathological specimen of breast cancer cells, retraction artifact during histological processing mimics true lymphovascular invasion (LVI). The accurate determination of the presence or absence of LVI is a factor in determining risk of having a positive sentinel node, or having additional positive axillary nodes ...

journal_title：Journal of breast cancer

authors： Zaorsky NG,Patil N,Freedman GM,Tuluc M

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:We aimed to confirm the prognostic and predictive value of p53 expression, particularly in invasive breast cancer patients, according to immunohistochemical hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) status. METHODS:Immunohistochemical data for p53, estrogen receptor, progesteron...

journal_title：Journal of breast cancer

authors： Ahn SH,Kim HJ,Han W,Cho J,Gong G,Jung KH,Kim SB,Son BH,Lee JW

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:We investigated the feasibility of using surgical clips as markers for tumor localization and their effect on the imaging evaluation of treatment responses after neoadjuvant chemotherapy (NAC). METHODS:A total of 16 breast cancers confirmed by needle biopsy in 15 patients were included in this study from Octob...

journal_title：Journal of breast cancer

authors： Youn I,Choi SH,Kook SH,Choi YJ,Park CH,Park YL,Kim DH

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:The Gail model is one of the most widely used tools to assess the risk of breast cancer. However, it is known to overestimate breast cancer risk for Asian women. Here, we validate the Gail model and the Korean model using Korean data, and subsequently update and revalidate the Korean model using recent data. M...

journal_title：Journal of breast cancer

authors： Min JW,Chang MC,Lee HK,Hur MH,Noh DY,Yoon JH,Jung Y,Yang JH,Korean Breast Cancer Society.

更新日期：2014-09-01 00:00:00

abstract：:Oncoplastic surgery has revolutionized the field of breast conserving surgery (BCS). The final aims of this technique are to obtain an adequate resection margin that will reduce the rate of local recurrence while simultaneously improving cosmetic outcomes. To obtain successful results after oncoplastic surgery, it is ...

journal_title：Journal of breast cancer

authors： Yang JD,Lee JW,Kim WW,Jung JH,Park HY

更新日期：2011-12-01 00:00:00

abstract：:Multiple symmetric lipomatosis (MSL), or Madelung's disease, is a rare disease of unknown etiology. It is characterized by the presence of loose adipose tissue deposits localized in the cervical region and upper body. MSL presenting as bilateral huge gynecomastia is an extremely rare phenomenon. The present report des...

journal_title：Journal of breast cancer

authors： Jang JH,Lee A,Han SA,Ryu JK,Song JY

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:We investigated the relationship between BRCA mutations, pathological findings, and magnetic resonance imaging (MRI) features in patients with breast cancer at risk for the mutation. METHODS:Genetic testing for BRCA mutations was performed in 275 breast cancer patients with at least one risk factor for the mut...

journal_title：Journal of breast cancer

authors： Noh JM,Han BK,Choi DH,Rhee SJ,Cho EY,Huh SJ,Park W,Park H,Nam SJ,Lee JE,Kil WH

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:Somatic mutations of the chromatin remodeling AT-rich interactive domain 1A (SWI-like) gene (ARID1A) have been identified in many human cancers, including breast cancer. The purpose of this study was to evaluate the nuclear expression of ARID1A in breast cancers by immunohistochemistry (IHC) and to correlate th...

journal_title：Journal of breast cancer

authors： Cho HD,Lee JE,Jung HY,Oh MH,Lee JH,Jang SH,Kim KJ,Han SW,Kim SY,Kim HJ,Bae SB,Lee HJ

更新日期：2015-12-01 00:00:00

abstract：:Apocrine encapsulated papillary carcinoma (EPC) of the breast is a rare neoplasm, and only 10 cases have been reported in the literature to date. Although EPC by definition lacks a peripheral myoepithelial layer, all previously published apocrine EPC cases were clinically indolent and lacked a conventional invasive co...

journal_title：Journal of breast cancer

authors： Kővári B,Ormándi K,Simonka Z,Vörös A,Cserni G

更新日期：2018-06-01 00:00:00

abstract：:Oxygen is crucial to maintain the homeostasis in aerobic cells. Hypoxia is a condition in which cells are deprived of the oxygen supply necessary for their optimum performance. Whereas oxygen deprivation may occur in normal physiological processes, hypoxia is frequently associated with pathological conditions. It has ...

journal_title：Journal of breast cancer

authors： Daimiel I

更新日期：2019-05-13 00:00:00

abstract：Purpose:Breast cancer treatments, including chemotherapy, administered in combination with glucocorticoids can induce hyperglycemia. This study aimed to investigate the effect of hyperglycemia during adjuvant chemotherapy on the prognosis of breast cancer patients without a known history of diabetes. Methods:In this s...

journal_title：Journal of breast cancer

authors： Ahn HR,Kang SY,Youn HJ,Jung SH

更新日期：2020-08-05 00:00:00

abstract：PURPOSE:Metastasis and local recurrence are the primary causes of treatment failure and patient death in breast cancer. The aim of this study was to validate a metastasis- and local recurrenceassociated biomarker for prognostic evaluation and planning treatment strategies. METHODS:Formalin-fixed, paraffin-embedded tis...

journal_title：Journal of breast cancer

authors： Ye F,Zhong X,Qiu Y,Yang L,Wei B,Zhang Z,Bu H

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:The MammaPrint™ gene signature, currently used in clinical practice, provides prognostic information regarding the recurrence and potential metastasis in breast cancer patients. However, the prognostic information of the 70 genes included can only be estimated at the RNA expression level. In this study, we inve...

journal_title：Journal of breast cancer

authors： Fatima A,Tariq F,Malik MFA,Qasim M,Haq F

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:This study was performed to assess frequency, timings of occurrence, and predictors of radiologic lung damage (RLD) after forward-planned intensity-modulated radiotherapy (FIMRT) for whole breast irradiation. METHODS:We retrospectively reviewed medical records of 157 breast cancer patients and each of their se...

journal_title：Journal of breast cancer

authors： Kim H,Bae H,Lee MY,Cheong KH,Kim KJ,Han T,Kang SK,Park S,Hwang T,Yoon JW,Kim LS

更新日期：2014-03-01 00:00:00

abstract：:We describe a patient with breast cancer who relapsed with an extensive pulmonary lymphovascular tumor embolism. A 38-year-old female, who previously received neoadjuvant chemotherapy and curative resection of breast cancer, underwent adjuvant chemotherapy and was referred to the emergency room because of sudden-onset...

journal_title：Journal of breast cancer

authors： Yang Y,Choi Y,Beom SH,Kim JW,Joen YK,Kim NJ,Kim JH,Im SA,Lee KH

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:Re-excisions after breast-conserving surgery (BCS) for breast cancer cause delays in the adjuvant treatment, increased morbidity, and leads to poor aesthetic results. Thus, efforts to reduce the re-excision rate are essential. This study aimed to conclusively determine the re-excision rate and the factors assoc...

journal_title：Journal of breast cancer

authors： Jung W,Kang E,Kim SM,Kim D,Hwang Y,Sun Y,Yom CK,Kim SW

更新日期：2012-12-01 00:00:00