Abstract:
:The median time of brain metastasis from the diagnosis of breast cancer is approximately 3 years. In this case report, a 69-year-old woman demonstrated cerebellar ataxia. Brain magnetic resonance imaging revealed enhanced lesions in bilateral cerebellar hemispheres. She had undergone surgery, radiation, and chemotherapy for uterine and breast cancer 24 years prior and 16 years prior, respectively. Although she had not received any anticancer treatment for 10 years, no recurrences were identified using whole body scans. A partial tumor resection was performed and the histological diagnosis was an adenocarcinoma from breast cancer. As no extracranial lesions were found, gamma-knife irradiation was performed, without additional systemic chemotherapy. One month posttreatment, the tumors dramatically reduced in size and the patient completely recovered from cerebellar ataxia. Systemic chemotherapy is not always required for brain metastasis from breast cancer with a long interval period, as long as no evidence of extracranial recurrence is detected.
journal_name
J Breast Cancerjournal_title
Journal of breast cancerauthors
Yamada SM,Tomita Y,Shibui S,Kurokawa T,Baba Ydoi
10.4048/jbc.2017.20.2.212subject
Has Abstractpub_date
2017-06-01 00:00:00pages
212-216issue
2eissn
1738-6756issn
2092-9900journal_volume
20pub_type
abstract:Purpose:Breast cancer treatments, including chemotherapy, administered in combination with glucocorticoids can induce hyperglycemia. This study aimed to investigate the effect of hyperglycemia during adjuvant chemotherapy on the prognosis of breast cancer patients without a known history of diabetes. Methods:In this s...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2020.23.e44
更新日期:2020-08-05 00:00:00
abstract::The combination of luteinizing hormone-releasing hormone analogs (LHRHa) with tamoxifen is used as a standard postoperative adjuvant therapy in patients with hormone receptor-positive/premenopausal breast cancer. Long-acting LHRHa formulations offer advantages in terms of patient convenience. However, data on the effe...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2020.23.e57
更新日期:2020-10-26 00:00:00
abstract:Purpose:BRCA1/2 mutations are associated with risks of breast and ovarian cancer. In Korea, incidences of BRCA1/2 genetic testing and risk-reducing surgery (RRS) have increased with insurance coverage and the Angelina Jolie effect. The aim of this study was to identify trends in RRS performed in Korean women with the B...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2020.23.e61
更新日期:2020-12-03 00:00:00
abstract:PURPOSE:The MammaPrint™ gene signature, currently used in clinical practice, provides prognostic information regarding the recurrence and potential metastasis in breast cancer patients. However, the prognostic information of the 70 genes included can only be estimated at the RNA expression level. In this study, we inve...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2017.20.3.246
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:The role of first-line trastuzumab-based therapy has been firmly established in patients with human epidermal growth factor receptor-2 (HER2) positive metastatic breast cancer. In this trial, we evaluated the efficacy and safety of a vinorelbine and trastuzumab combination chemotherapy in patients who were pret...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2011.14.2.140
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:To investigate the significance of the cortex-hilum (CH) area ratio and longitudinal-transverse (LT) axis ratio and the blood flow pattern for diagnosis of metastatic axillary lymph nodes by ultrasound in breast cancer patients. METHODS:From October 2005 to July 2006, we prospectively evaluated axillary nodes ...
journal_title:Journal of breast cancer
pub_type: 杂志文章
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更新日期:2012-03-01 00:00:00
abstract:Purpose:The exact mechanism regulating fibronectin (FN) expression in breast cancer cells has not been fully elucidated. In this study, we investigated the pharmacological mechanism of berberine (BBR) with respect to FN expression in triple-negative breast cancer (TNBC) cells. Methods:The clinical significance of FN m...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2018.21.1.21
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:We aimed to confirm the prognostic and predictive value of p53 expression, particularly in invasive breast cancer patients, according to immunohistochemical hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) status. METHODS:Immunohistochemical data for p53, estrogen receptor, progesteron...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2013.16.4.386
更新日期:2013-12-01 00:00:00
abstract:Purpose:Previous oncological studies showed that lymph node ratio (LNR) (ratio of number of lymph nodes that tested positive for metastasis to the total number of lymph nodes examined) is a negative indicator of cancer survival. The American Joint Committee on Cancer (AJCC) staging system incorporates tumor size, lymph...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2018.21.e35
更新日期:2018-09-01 00:00:00
abstract:Purpose:The aim of this study was to investigate the association of telomere length with breast cancer risk. We simultaneously explored the association between telomerase reverse transcriptase gene polymorphisms and telomere length. Methods:We used real-time quantitative polymerase chain reaction to measure relative t...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2018.21.e52
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:We evaluated the effect of local recurrence (LR) and regional recurrence (RR) on distant metastasis and survival in patients treated with breast conservation therapy (BCT). METHODS:We analyzed 907 patients who were treated for invasive breast cancer between 1993 and 2006. With 53 months of follow-up, 28 patien...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2011.14.3.191
更新日期:2011-09-01 00:00:00
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journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2015.18.3.285
更新日期:2015-09-01 00:00:00
abstract::Apocrine encapsulated papillary carcinoma (EPC) of the breast is a rare neoplasm, and only 10 cases have been reported in the literature to date. Although EPC by definition lacks a peripheral myoepithelial layer, all previously published apocrine EPC cases were clinically indolent and lacked a conventional invasive co...
journal_title:Journal of breast cancer
pub_type:
doi:10.4048/jbc.2018.21.2.227
更新日期:2018-06-01 00:00:00
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journal_title:Journal of breast cancer
pub_type:
doi:10.4048/jbc.2016.19.2.214
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Breast volume assessment is one of the most important steps during implant-based breast reconstruction because it is critical in selecting implant size. According to previous studies, there is a close relationship between the mastectomy specimen weight and resected breast volume. The aim of this study was to ev...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2017.20.1.98
更新日期:2017-03-01 00:00:00
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journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2016.19.3.301
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:The frequency of immediate breast reconstruction (IBR) is increasing, and the types of reconstruction used are diverse. Adjuvant chemotherapy is a life-saving intervention in selected high-risk breast cancer patients. The aim of our study was to determine how IBR and type of reconstruction affect the timing of ...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2011.14.4.322
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:The Gail model is one of the most widely used tools to assess the risk of breast cancer. However, it is known to overestimate breast cancer risk for Asian women. Here, we validate the Gail model and the Korean model using Korean data, and subsequently update and revalidate the Korean model using recent data. M...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2014.17.3.226
更新日期:2014-09-01 00:00:00
abstract::Since recurrent bilateral breast infection due to nontuberculous mycobacterium (NTM) is rare, its diagnosis is easily overlooked; in addition, complete recovery is often difficult to achieve. We report a case of recurrent bilateral infection in a 35-year-old woman who had completed treatment for NTM. Although various ...
journal_title:Journal of breast cancer
pub_type:
doi:10.4048/jbc.2014.17.3.295
更新日期:2014-09-01 00:00:00
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journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2012.15.2.218
更新日期:2012-06-01 00:00:00
abstract::Breast cancer generally develops in older women and its incidence is continuing to increase with increasing age of the population. The pathology and biology of breast cancer seem to be different in the elderly, often resulting in the undertreatment of elderly patients and thus in higher rates of recurrence and mortal-...
journal_title:Journal of breast cancer
pub_type: 杂志文章,评审
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更新日期:2015-09-01 00:00:00
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journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2016.19.4.417
更新日期:2016-12-01 00:00:00
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journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2014.17.4.332
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:We investigated the relationship between BRCA mutations, pathological findings, and magnetic resonance imaging (MRI) features in patients with breast cancer at risk for the mutation. METHODS:Genetic testing for BRCA mutations was performed in 275 breast cancer patients with at least one risk factor for the mut...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2013.16.3.308
更新日期:2013-09-01 00:00:00
abstract::We describe a patient with breast cancer who relapsed with an extensive pulmonary lymphovascular tumor embolism. A 38-year-old female, who previously received neoadjuvant chemotherapy and curative resection of breast cancer, underwent adjuvant chemotherapy and was referred to the emergency room because of sudden-onset...
journal_title:Journal of breast cancer
pub_type:
doi:10.4048/jbc.2012.15.1.128
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:Re-excisions after breast-conserving surgery (BCS) for breast cancer cause delays in the adjuvant treatment, increased morbidity, and leads to poor aesthetic results. Thus, efforts to reduce the re-excision rate are essential. This study aimed to conclusively determine the re-excision rate and the factors assoc...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2012.15.4.412
更新日期:2012-12-01 00:00:00
abstract::Breast metastasis from gastric carcinoma is rare. We present a case of right breast mass with microcalcification in which the diagnosis of poorly differentiated adenocarcinoma from the stomach was made after a biopsy. Pleomorphic microcalcification was noted in the ill-defined breast mass, which is a rare feature in b...
journal_title:Journal of breast cancer
pub_type:
doi:10.4048/jbc.2012.15.3.356
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:MicroRNAs (miRNAs) are a major class of small endogenous RNA molecules that posttranscriptionally regulate the expression of most genes in the human genome. miRNAs are often located in chromosomal fragile sites, which are suscept-ible to amplification or deletion. Chromosomal deletions are frequent events in br...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2016.19.2.148
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:The objective of this study was to describe the evolution of health-related quality of life (HRQOL) in a cohort of breast cancer patients over 1 year after surgery and to analyse the predictive ability of HRQOL measurement instruments. METHODS:Observational, multicenter and prospective study of a cohort of bre...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2013.16.1.104
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:Metastasis and local recurrence are the primary causes of treatment failure and patient death in breast cancer. The aim of this study was to validate a metastasis- and local recurrenceassociated biomarker for prognostic evaluation and planning treatment strategies. METHODS:Formalin-fixed, paraffin-embedded tis...
journal_title:Journal of breast cancer
pub_type: 杂志文章
doi:10.4048/jbc.2017.20.2.142
更新日期:2017-06-01 00:00:00