Berberine Suppresses Fibronectin Expression through Inhibition of c-Jun Phosphorylation in Breast Cancer Cells.

abstract：PURPOSE:MicroRNAs (miRNAs) are a major class of small endogenous RNA molecules that posttranscriptionally regulate the expression of most genes in the human genome. miRNAs are often located in chromosomal fragile sites, which are suscept-ible to amplification or deletion. Chromosomal deletions are frequent events in br...

journal_title：Journal of breast cancer

authors： Damavandi Z,Torkashvand S,Vasei M,Soltani BM,Tavallaei M,Mowla SJ

更新日期：2016-06-01 00:00:00

abstract：:On a pathological specimen of breast cancer cells, retraction artifact during histological processing mimics true lymphovascular invasion (LVI). The accurate determination of the presence or absence of LVI is a factor in determining risk of having a positive sentinel node, or having additional positive axillary nodes ...

journal_title：Journal of breast cancer

authors： Zaorsky NG,Patil N,Freedman GM,Tuluc M

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:Metastasis and local recurrence are the primary causes of treatment failure and patient death in breast cancer. The aim of this study was to validate a metastasis- and local recurrenceassociated biomarker for prognostic evaluation and planning treatment strategies. METHODS:Formalin-fixed, paraffin-embedded tis...

journal_title：Journal of breast cancer

authors： Ye F,Zhong X,Qiu Y,Yang L,Wei B,Zhang Z,Bu H

更新日期：2017-06-01 00:00:00

abstract：:Internationally, breast cancer is the most common female cancer, and is induced by a combination of environmental, genetic, and epigenetic risk factors. Despite the advancement of imaging techniques, invasive sampling of breast epithelial cells is the only definitive diagnostic procedure for patients with breast cance...

journal_title：Journal of breast cancer

authors： Cheuk IW,Shin VY,Kwong A

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:We evaluated the effect of local recurrence (LR) and regional recurrence (RR) on distant metastasis and survival in patients treated with breast conservation therapy (BCT). METHODS:We analyzed 907 patients who were treated for invasive breast cancer between 1993 and 2006. With 53 months of follow-up, 28 patien...

journal_title：Journal of breast cancer

authors： Lee JS,Kim SI,Park HS,Lee JS,Park S,Park BW

更新日期：2011-09-01 00:00:00

abstract：:The combination of luteinizing hormone-releasing hormone analogs (LHRHa) with tamoxifen is used as a standard postoperative adjuvant therapy in patients with hormone receptor-positive/premenopausal breast cancer. Long-acting LHRHa formulations offer advantages in terms of patient convenience. However, data on the effe...

journal_title：Journal of breast cancer

authors： Lee YJ,Wu ZY,Kim HJ,Lee JW,Chung IY,Kim J,Lee SB,Son BH,Kim SB,Jung JH,Gong G,Ahn SH,Ko B

更新日期：2020-10-26 00:00:00

abstract：Purpose:Pokemon, also known as ZBTB7A, belongs to the POZ and Krüppel (POK) family of transcription repressors and is implicated in tumor progression as a key proto-oncogene. This present study aimed at determining the mechanism by which Pokemon inhibits transforming growth factor β (TGFβ)-Smad4 pathway-dependent proli...

journal_title：Journal of breast cancer

authors： Chen L,Zhong J,Liu JH,Liao DF,Shen YY,Zhong XL,Xiao X,Ding WJ,Peng XD,Xiong W,Zu XY

更新日期：2019-02-15 00:00:00

abstract：Purpose:BRCA1/2 mutations are associated with risks of breast and ovarian cancer. In Korea, incidences of BRCA1/2 genetic testing and risk-reducing surgery (RRS) have increased with insurance coverage and the Angelina Jolie effect. The aim of this study was to identify trends in RRS performed in Korean women with the B...

journal_title：Journal of breast cancer

authors： Jung SM,Ryu JM,Park HS,Park JS,Kang E,Lee S,Lee HB,Youn HJ,Yoo TK,Kim J,Lee JE,Han SA,Kim D,Kim SW,Korean Hereditary Breast Cancer Study Group.

更新日期：2020-12-03 00:00:00

abstract：PURPOSE:The reliability of the quantitative measurement of breast density with a semi-automated thresholding method (Cumulus™) has mainly been investigated with film mammograms. This study aimed to evaluate the intrarater reproducibility of percent density (PD) by Cumulus™ with digital mammograms. METHODS:This study i...

journal_title：Journal of breast cancer

authors： Sohn G,Lee JW,Park SW,Park J,Woo J,Kim HJ,Shin HJ,Kim HH,Jung KH,Sung J,Lee SW,Son BH,Ahn SH

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:The objective of this study was to describe the evolution of health-related quality of life (HRQOL) in a cohort of breast cancer patients over 1 year after surgery and to analyse the predictive ability of HRQOL measurement instruments. METHODS:Observational, multicenter and prospective study of a cohort of bre...

journal_title：Journal of breast cancer

authors： Moro-Valdezate D,Peiró S,Buch-Villa E,Caballero-Gárate A,Morales-Monsalve MD,Martínez-Agulló A,Checa-Ayet F,Ortega-Serrano J

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:We investigated the relationship between BRCA mutations, pathological findings, and magnetic resonance imaging (MRI) features in patients with breast cancer at risk for the mutation. METHODS:Genetic testing for BRCA mutations was performed in 275 breast cancer patients with at least one risk factor for the mut...

journal_title：Journal of breast cancer

authors： Noh JM,Han BK,Choi DH,Rhee SJ,Cho EY,Huh SJ,Park W,Park H,Nam SJ,Lee JE,Kil WH

更新日期：2013-09-01 00:00:00

abstract：Purpose:Breast cancer treatments, including chemotherapy, administered in combination with glucocorticoids can induce hyperglycemia. This study aimed to investigate the effect of hyperglycemia during adjuvant chemotherapy on the prognosis of breast cancer patients without a known history of diabetes. Methods:In this s...

journal_title：Journal of breast cancer

authors： Ahn HR,Kang SY,Youn HJ,Jung SH

更新日期：2020-08-05 00:00:00

abstract：PURPOSE:We aimed to confirm the prognostic and predictive value of p53 expression, particularly in invasive breast cancer patients, according to immunohistochemical hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) status. METHODS:Immunohistochemical data for p53, estrogen receptor, progesteron...

journal_title：Journal of breast cancer

authors： Ahn SH,Kim HJ,Han W,Cho J,Gong G,Jung KH,Kim SB,Son BH,Lee JW

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Breast cancer subtype correlates with response to systemic therapy and overall survival (OS), but its impact on lymphatic spread is incompletely understood. In this study, we used the Surveillance, Epidemiology, and End Results registry to assess whether the subtype can predict the presence of nodal metastasis ...

journal_title：Journal of breast cancer

authors： Mattes MD,Bhatia JK,Metzger D,Ashamalla H,Katsoulakis E

更新日期：2015-06-01 00:00:00

abstract：Purpose:This study was aimed at identifying the influence of initial weight and weight change during neoadjuvant chemotherapy (NAC) on pathologic complete response (pCR) and long-term survival in Chinese patients with operable breast cancer. Methods:We conducted a retrospective study using data from 409 female patient...

journal_title：Journal of breast cancer

authors： Fang Q,Huang J,Gan L,Shen K,Chen X,Wu B

更新日期：2019-08-26 00:00:00

abstract：PURPOSE:The MammaPrint™ gene signature, currently used in clinical practice, provides prognostic information regarding the recurrence and potential metastasis in breast cancer patients. However, the prognostic information of the 70 genes included can only be estimated at the RNA expression level. In this study, we inve...

journal_title：Journal of breast cancer

authors： Fatima A,Tariq F,Malik MFA,Qasim M,Haq F

更新日期：2017-09-01 00:00:00

abstract：Purpose:The 8th edition of the American Joint Committee on Cancer (AJCC) staging manual introduced a new prognostic staging system for breast cancer. This study aimed to evaluate the changes in staging distribution and predictive power of the new staging system. Methods:Of the 12,275 patients with breast cancer identi...

journal_title：Journal of breast cancer

authors： Kim EJ,Park HS,Kim JY,Kim SI,Cho YU,Park BW

更新日期：2020-01-09 00:00:00

abstract：Purpose:The benefit of post-mastectomy radiation therapy (PMRT) in patients with breast cancer who achieve ypN0 following neoadjuvant chemotherapy (NAC) has not yet been established. This study aimed to identify the role of PMRT in patients who achieve ypN0 according to molecular subtype. Methods:We identified patient...

journal_title：Journal of breast cancer

authors： Cho WK,Park W,Choi DH,Kim YB,Kim JH,Kim SS,Kim K,Kim JH,Ahn SJ,Lee SY,Lee J,Kim SW,Kwon J,Ahn KJ

更新日期：2019-05-13 00:00:00

abstract：:We describe a patient with breast cancer who relapsed with an extensive pulmonary lymphovascular tumor embolism. A 38-year-old female, who previously received neoadjuvant chemotherapy and curative resection of breast cancer, underwent adjuvant chemotherapy and was referred to the emergency room because of sudden-onset...

journal_title：Journal of breast cancer

authors： Yang Y,Choi Y,Beom SH,Kim JW,Joen YK,Kim NJ,Kim JH,Im SA,Lee KH

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:This study was performed to assess frequency, timings of occurrence, and predictors of radiologic lung damage (RLD) after forward-planned intensity-modulated radiotherapy (FIMRT) for whole breast irradiation. METHODS:We retrospectively reviewed medical records of 157 breast cancer patients and each of their se...

journal_title：Journal of breast cancer

authors： Kim H,Bae H,Lee MY,Cheong KH,Kim KJ,Han T,Kang SK,Park S,Hwang T,Yoon JW,Kim LS

更新日期：2014-03-01 00:00:00

abstract：Purpose:Triple-negative breast cancer (TNBC) is associated with poor prognosis with limited treatment options. Angiogenesis is known to be involved in the progression of TNBC, and targeting this pathway results in modest clinical benefits. In this study, we analyzed the role of tumor microvascular endothelial Notch1 (E...

journal_title：Journal of breast cancer

authors： Kim D,Lee J,Kang J,Kim SH,Yoo TK,Oh S,Lee A

更新日期：2019-12-12 00:00:00

abstract：:The prognosis associated with brain metastasis arising from breast cancer is very poor. Eribulin is a microtubule dynamic inhibitor synthesized from halichondrin B, a natural marine product. In a phase III study (EMBRACE), eribulin improved overall survival in patients with heavily pretreated metastatic breast cancers...

journal_title：Journal of breast cancer

authors： Byun KD,Ahn SG,Baik HJ,Lee A,Bae KB,An MS,Kim KH,Shin JH,Park HK,Cho H,Jeong J,Kim TH

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:As doxorubicin cardiotoxicity is considered irreversible, early detection of cardiotoxicity and prevention of overt heart failure is essential. Although there are monitoring guidelines for cardiotoxicity, optimal timing for early detection of subclinical doxorubicin cardiotoxicity is still obscure. The purpose ...

journal_title：Journal of breast cancer

authors： Chung WB,Yi JE,Jin JY,Choi YS,Park CS,Park WC,Song BJ,Youn HJ

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:The Gail model is one of the most widely used tools to assess the risk of breast cancer. However, it is known to overestimate breast cancer risk for Asian women. Here, we validate the Gail model and the Korean model using Korean data, and subsequently update and revalidate the Korean model using recent data. M...

journal_title：Journal of breast cancer

authors： Min JW,Chang MC,Lee HK,Hur MH,Noh DY,Yoon JH,Jung Y,Yang JH,Korean Breast Cancer Society.

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:Re-excisions after breast-conserving surgery (BCS) for breast cancer cause delays in the adjuvant treatment, increased morbidity, and leads to poor aesthetic results. Thus, efforts to reduce the re-excision rate are essential. This study aimed to conclusively determine the re-excision rate and the factors assoc...

journal_title：Journal of breast cancer

authors： Jung W,Kang E,Kim SM,Kim D,Hwang Y,Sun Y,Yom CK,Kim SW

更新日期：2012-12-01 00:00:00

abstract：:Malignant melanoma rarely originates from the female nipple. Tumors that develop on the skin of the breast are often subject to a delayed diagnosis. Cytologic examination provides excellent diagnostic capabilities and is a safe procedure with a lower risk of local implantation, compared to needle or incisional biopsy....

journal_title：Journal of breast cancer

authors： Nagata Y,Yoshioka M,Uramoto H,Tsurudome Y,Yamada S,Hanagiri T,Tanaka F

更新日期：2018-03-01 00:00:00

abstract：:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis belong to a severe dermatopathic spectrum that includes frequently fatal mucocutaneous manifestations consisting of whole epidermal necrosis and sloughing with bullous transformation, blistering, and further skin detachment. Notably, cancer patients are at ...

journal_title：Journal of breast cancer

authors： López-Gómez V,Yarza R,Muñoz-González H,Revilla E,Enrech S,González-Valle O,Tolosa P,Ciruelos E

更新日期：2019-09-18 00:00:00

abstract：PURPOSE:Patients with recurrent breast cancer usually die of their disease, even after radical surgery and adjuvant therapies which could reduce the odds of dying. Many studies analyzed and compared patients who died of recurrent disease with those that died without recurrent disease. However, less attention has been p...

journal_title：Journal of breast cancer

authors： Song WJ,Kim KI,Park SH,Kwon MS,Lee TH,Park HK,An JS

更新日期：2012-06-01 00:00:00

abstract：Purpose:Whether tamoxifen affects the risk of neurodegenerative disease is controversial. This nationwide population-based study investigated the risk of Parkinson's disease (PD) associated with tamoxifen treatment in female patients with breast cancer using Taiwan's National Health Insurance Research Database. Method...

journal_title：Journal of breast cancer

authors： Hong CT,Chan L,Hu CJ,Lin CM,Hsu CY,Lin MC

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:Surgical clips are used as a target for postoperative breast radiotherapy, and displacement of surgical clips would result in inaccurate delivery of radiation. We investigated the displacement range of surgical clips in the breast during postoperative radiotherapy following breast-conserving surgery. METHODS:A...

journal_title：Journal of breast cancer

authors： Sung S,Lee JH,Lee JH,Kim SH,Kwak YK,Lee SW,Jeon YW,Suh YJ

更新日期：2016-12-01 00:00:00