Effect Modification of Hormonal Therapy by p53 Status in Invasive Breast Cancer.

abstract：:The prognosis associated with brain metastasis arising from breast cancer is very poor. Eribulin is a microtubule dynamic inhibitor synthesized from halichondrin B, a natural marine product. In a phase III study (EMBRACE), eribulin improved overall survival in patients with heavily pretreated metastatic breast cancers...

journal_title：Journal of breast cancer

authors： Byun KD,Ahn SG,Baik HJ,Lee A,Bae KB,An MS,Kim KH,Shin JH,Park HK,Cho H,Jeong J,Kim TH

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:MicroRNAs (miRNAs) are a major class of small endogenous RNA molecules that posttranscriptionally regulate the expression of most genes in the human genome. miRNAs are often located in chromosomal fragile sites, which are suscept-ible to amplification or deletion. Chromosomal deletions are frequent events in br...

journal_title：Journal of breast cancer

authors： Damavandi Z,Torkashvand S,Vasei M,Soltani BM,Tavallaei M,Mowla SJ

更新日期：2016-06-01 00:00:00

abstract：:The median time of brain metastasis from the diagnosis of breast cancer is approximately 3 years. In this case report, a 69-year-old woman demonstrated cerebellar ataxia. Brain magnetic resonance imaging revealed enhanced lesions in bilateral cerebellar hemispheres. She had undergone surgery, radiation, and chemothera...

journal_title：Journal of breast cancer

authors： Yamada SM,Tomita Y,Shibui S,Kurokawa T,Baba Y

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:The role of first-line trastuzumab-based therapy has been firmly established in patients with human epidermal growth factor receptor-2 (HER2) positive metastatic breast cancer. In this trial, we evaluated the efficacy and safety of a vinorelbine and trastuzumab combination chemotherapy in patients who were pret...

journal_title：Journal of breast cancer

authors： Lee YR,Huh SJ,Lee DH,Yoon HH,Seol YM,Choi YJ,Kwon KA,Lee S,Oh SY,Kim SH,Kim HJ,Kwon HC

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:We evaluated the effect of local recurrence (LR) and regional recurrence (RR) on distant metastasis and survival in patients treated with breast conservation therapy (BCT). METHODS:We analyzed 907 patients who were treated for invasive breast cancer between 1993 and 2006. With 53 months of follow-up, 28 patien...

journal_title：Journal of breast cancer

authors： Lee JS,Kim SI,Park HS,Lee JS,Park S,Park BW

更新日期：2011-09-01 00:00:00

abstract：Purpose:We aimed to investigate the clinicopathologic factors associated with distant metastasis (DM) and post-recurrence overall survival (OS) after salvage treatments for isolated locoregional recurrence (ILRR) of breast cancer and identify long-term surviving patients for providing a more personalized therapy. Meth...

journal_title：Journal of breast cancer

authors： Kim BH,Shin KH,Chie EK,Kim JH,Kim K,Hwang KT,Kim J,Choi IS,Park JH,Kim S

更新日期：2020-04-29 00:00:00

abstract：:The combination of luteinizing hormone-releasing hormone analogs (LHRHa) with tamoxifen is used as a standard postoperative adjuvant therapy in patients with hormone receptor-positive/premenopausal breast cancer. Long-acting LHRHa formulations offer advantages in terms of patient convenience. However, data on the effe...

journal_title：Journal of breast cancer

authors： Lee YJ,Wu ZY,Kim HJ,Lee JW,Chung IY,Kim J,Lee SB,Son BH,Kim SB,Jung JH,Gong G,Ahn SH,Ko B

更新日期：2020-10-26 00:00:00

abstract：:The Korean Breast Cancer Society (KBCS) has reported a nationwide breast cancer data since 1996. We present a comprehensive report on the facts and trends of breast cancer in Korea in 2013. Data on the newly diagnosed patients in the year 2013 were collected from 99 hospitals by using nationwide questionnaire survey. ...

journal_title：Journal of breast cancer

authors： Min SY,Kim Z,Hur MH,Yoon CS,Park EH,Jung KW,Korean Breast Cancer Society Consortium.

更新日期：2016-03-01 00:00:00

abstract：:[This corrects the article on p. 192 in vol. 20, PMID: 28690656.]. ...

journal_title：Journal of breast cancer

authors： Chu AJ,Chang JM,Cho N,Moon WK

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:In our previous studies we showed that upregulating claudin-6 (CLDN6) expression may contribute to preventing breast cancer, and that 17β-estradiol induces a concentration- and time-related effect on CLDN6 mRNA and protein expression in MCF-7 cells. However, the mechanisms of 17β-estradiol regulation of CLDN6 a...

journal_title：Journal of breast cancer

authors： Yafang L,Qiong W,Yue R,Xiaoming X,Lina Y,Mingzi Z,Ting Z,Yulin L,Chengshi Q

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:The purpose of this study was to assess the incidence of invasive lobular carcinoma (ILC) and to compare the clinicopathological features and treatment results after breast conserving surgery (BCS) followed by radiotherapy between ILC and invasive ductal carcinoma (IDC). METHODS:A total of 1,071 patients who u...

journal_title：Journal of breast cancer

authors： Park JS,Choi DH,Huh SJ,Park W,Kim YI,Nam SJ,Lee JE,Kil WH

更新日期：2015-09-01 00:00:00

abstract：Purpose:Triple-negative breast cancer (TNBC) is associated with poor prognosis with limited treatment options. Angiogenesis is known to be involved in the progression of TNBC, and targeting this pathway results in modest clinical benefits. In this study, we analyzed the role of tumor microvascular endothelial Notch1 (E...

journal_title：Journal of breast cancer

authors： Kim D,Lee J,Kang J,Kim SH,Yoo TK,Oh S,Lee A

更新日期：2019-12-12 00:00:00

abstract：:ESR1 mutation is frequently encountered in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC), especially after aromatase inhibitor (AI) therapy, as a mechanism of resistance to endocrine therapy. Circulating tumor DNA-based detection of ESR1 mutatio...

journal_title：Journal of breast cancer

authors： Carausu M,Melaabi S,Pierga JY,Bidard FC,Cabel L

更新日期：2019-12-19 00:00:00

abstract：:Since recurrent bilateral breast infection due to nontuberculous mycobacterium (NTM) is rare, its diagnosis is easily overlooked; in addition, complete recovery is often difficult to achieve. We report a case of recurrent bilateral infection in a 35-year-old woman who had completed treatment for NTM. Although various ...

journal_title：Journal of breast cancer

authors： Yoo H,Choi SH,Kim YJ,Kim SJ,Cho YU,Choi SJ

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:We investigated the relationship between BRCA mutations, pathological findings, and magnetic resonance imaging (MRI) features in patients with breast cancer at risk for the mutation. METHODS:Genetic testing for BRCA mutations was performed in 275 breast cancer patients with at least one risk factor for the mut...

journal_title：Journal of breast cancer

authors： Noh JM,Han BK,Choi DH,Rhee SJ,Cho EY,Huh SJ,Park W,Park H,Nam SJ,Lee JE,Kil WH

更新日期：2013-09-01 00:00:00

abstract：:Multiple symmetric lipomatosis (MSL), or Madelung's disease, is a rare disease of unknown etiology. It is characterized by the presence of loose adipose tissue deposits localized in the cervical region and upper body. MSL presenting as bilateral huge gynecomastia is an extremely rare phenomenon. The present report des...

journal_title：Journal of breast cancer

authors： Jang JH,Lee A,Han SA,Ryu JK,Song JY

更新日期：2014-12-01 00:00:00

abstract：Purpose:Pokemon, also known as ZBTB7A, belongs to the POZ and Krüppel (POK) family of transcription repressors and is implicated in tumor progression as a key proto-oncogene. This present study aimed at determining the mechanism by which Pokemon inhibits transforming growth factor β (TGFβ)-Smad4 pathway-dependent proli...

journal_title：Journal of breast cancer

authors： Chen L,Zhong J,Liu JH,Liao DF,Shen YY,Zhong XL,Xiao X,Ding WJ,Peng XD,Xiong W,Zu XY

更新日期：2019-02-15 00:00:00

abstract：PURPOSE:The MammaPrint™ gene signature, currently used in clinical practice, provides prognostic information regarding the recurrence and potential metastasis in breast cancer patients. However, the prognostic information of the 70 genes included can only be estimated at the RNA expression level. In this study, we inve...

journal_title：Journal of breast cancer

authors： Fatima A,Tariq F,Malik MFA,Qasim M,Haq F

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:We investigated the relationship between BRCA mutations and the distribution of familial cancers other than breast or ovary in high-risk breast cancer patients. METHODS:PATIENTS WITH BREAST CANCER WHO HAD AT LEAST ONE OF THE FOLLOWING RISK FACTORS WERE ENROLLED: reported family history of breast or ovarian can...

journal_title：Journal of breast cancer

authors： Noh JM,Choi DH,Baek H,Nam SJ,Lee JE,Kim JW,Ki CS,Park W,Huh SJ

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:Surgical clips are used as a target for postoperative breast radiotherapy, and displacement of surgical clips would result in inaccurate delivery of radiation. We investigated the displacement range of surgical clips in the breast during postoperative radiotherapy following breast-conserving surgery. METHODS:A...

journal_title：Journal of breast cancer

authors： Sung S,Lee JH,Lee JH,Kim SH,Kwak YK,Lee SW,Jeon YW,Suh YJ

更新日期：2016-12-01 00:00:00

abstract：:Breast cancer generally develops in older women and its incidence is continuing to increase with increasing age of the population. The pathology and biology of breast cancer seem to be different in the elderly, often resulting in the undertreatment of elderly patients and thus in higher rates of recurrence and mortal-...

journal_title：Journal of breast cancer

authors： Dimitrakopoulos FI,Kottorou A,Antonacopoulou AG,Makatsoris T,Kalofonos HP

更新日期：2015-09-01 00:00:00

abstract：:Malignant melanoma rarely originates from the female nipple. Tumors that develop on the skin of the breast are often subject to a delayed diagnosis. Cytologic examination provides excellent diagnostic capabilities and is a safe procedure with a lower risk of local implantation, compared to needle or incisional biopsy....

journal_title：Journal of breast cancer

authors： Nagata Y,Yoshioka M,Uramoto H,Tsurudome Y,Yamada S,Hanagiri T,Tanaka F

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Breast cancer subtype correlates with response to systemic therapy and overall survival (OS), but its impact on lymphatic spread is incompletely understood. In this study, we used the Surveillance, Epidemiology, and End Results registry to assess whether the subtype can predict the presence of nodal metastasis ...

journal_title：Journal of breast cancer

authors： Mattes MD,Bhatia JK,Metzger D,Ashamalla H,Katsoulakis E

更新日期：2015-06-01 00:00:00

abstract：Purpose:BRCA1/2 mutations are associated with risks of breast and ovarian cancer. In Korea, incidences of BRCA1/2 genetic testing and risk-reducing surgery (RRS) have increased with insurance coverage and the Angelina Jolie effect. The aim of this study was to identify trends in RRS performed in Korean women with the B...

journal_title：Journal of breast cancer

authors： Jung SM,Ryu JM,Park HS,Park JS,Kang E,Lee S,Lee HB,Youn HJ,Yoo TK,Kim J,Lee JE,Han SA,Kim D,Kim SW,Korean Hereditary Breast Cancer Study Group.

更新日期：2020-12-03 00:00:00

abstract：:Internationally, breast cancer is the most common female cancer, and is induced by a combination of environmental, genetic, and epigenetic risk factors. Despite the advancement of imaging techniques, invasive sampling of breast epithelial cells is the only definitive diagnostic procedure for patients with breast cance...

journal_title：Journal of breast cancer

authors： Cheuk IW,Shin VY,Kwong A

更新日期：2017-03-01 00:00:00

abstract：Purpose:The benefit of post-mastectomy radiation therapy (PMRT) in patients with breast cancer who achieve ypN0 following neoadjuvant chemotherapy (NAC) has not yet been established. This study aimed to identify the role of PMRT in patients who achieve ypN0 according to molecular subtype. Methods:We identified patient...

journal_title：Journal of breast cancer

authors： Cho WK,Park W,Choi DH,Kim YB,Kim JH,Kim SS,Kim K,Kim JH,Ahn SJ,Lee SY,Lee J,Kim SW,Kwon J,Ahn KJ

更新日期：2019-05-13 00:00:00

abstract：PURPOSE:The objective of this study was to describe the evolution of health-related quality of life (HRQOL) in a cohort of breast cancer patients over 1 year after surgery and to analyse the predictive ability of HRQOL measurement instruments. METHODS:Observational, multicenter and prospective study of a cohort of bre...

journal_title：Journal of breast cancer

authors： Moro-Valdezate D,Peiró S,Buch-Villa E,Caballero-Gárate A,Morales-Monsalve MD,Martínez-Agulló A,Checa-Ayet F,Ortega-Serrano J

更新日期：2013-03-01 00:00:00

abstract：:Oncoplastic surgery has revolutionized the field of breast conserving surgery (BCS). The final aims of this technique are to obtain an adequate resection margin that will reduce the rate of local recurrence while simultaneously improving cosmetic outcomes. To obtain successful results after oncoplastic surgery, it is ...

journal_title：Journal of breast cancer

authors： Yang JD,Lee JW,Kim WW,Jung JH,Park HY

更新日期：2011-12-01 00:00:00

abstract：Purpose:Breast cancer treatments, including chemotherapy, administered in combination with glucocorticoids can induce hyperglycemia. This study aimed to investigate the effect of hyperglycemia during adjuvant chemotherapy on the prognosis of breast cancer patients without a known history of diabetes. Methods:In this s...

journal_title：Journal of breast cancer

authors： Ahn HR,Kang SY,Youn HJ,Jung SH

更新日期：2020-08-05 00:00:00

abstract：:On a pathological specimen of breast cancer cells, retraction artifact during histological processing mimics true lymphovascular invasion (LVI). The accurate determination of the presence or absence of LVI is a factor in determining risk of having a positive sentinel node, or having additional positive axillary nodes ...

journal_title：Journal of breast cancer

authors： Zaorsky NG,Patil N,Freedman GM,Tuluc M

更新日期：2012-12-01 00:00:00