Abstract：
:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis belong to a severe dermatopathic spectrum that includes frequently fatal mucocutaneous manifestations consisting of whole epidermal necrosis and sloughing with bullous transformation, blistering, and further skin detachment. Notably, cancer patients are at higher risk of developing SJS than the general population as a consequence of both the nature of neoplastic disease and frequent exposure to anticancer drugs. Ribociclib is a newly approved cycline-dependent kinase inhibitor that has been recently associated with a single case of SJS. We hereby present a case of ribociclib-related SJS. Early detection of threatening skin lesions is crucial to permit the immediate discontinuation of ribociclib given the predictable and unacceptable risk level. In cases of established SJS, early aggressive support should be initiated, ribociclib should be abruptly discontinued, and specific treatment based on actual evidence should be started.
journal_name
J Breast Cancerjournal_title
Journal of breast cancerauthors
López-Gómez V,Yarza R,Muñoz-González H,Revilla E,Enrech S,González-Valle O,Tolosa P,Ciruelos Edoi
10.4048/jbc.2019.22.e44subject
Has Abstractpub_date
2019-09-18 00:00:00pages
661-666issue
4eissn
1738-6756issn
2092-9900journal_volume
22pub_type
abstract：:Breast cancer is the most common malignancy, and it is also the major cause of cancer-related deaths of women worldwide. Breast cancer treatment involves surgery, chemotherapy, radiation therapy, or combination therapy, and novel strategies are needed to boost the oncologic outcome. The non-metabolizable glucose analo...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2012.15.2.141
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:Somatic mutations of the chromatin remodeling AT-rich interactive domain 1A (SWI-like) gene (ARID1A) have been identified in many human cancers, including breast cancer. The purpose of this study was to evaluate the nuclear expression of ARID1A in breast cancers by immunohistochemistry (IHC) and to correlate th...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2015.18.4.339
更新日期：2015-12-01 00:00:00
abstract：:We describe a patient with breast cancer who relapsed with an extensive pulmonary lymphovascular tumor embolism. A 38-year-old female, who previously received neoadjuvant chemotherapy and curative resection of breast cancer, underwent adjuvant chemotherapy and was referred to the emergency room because of sudden-onset...
journal_title：Journal of breast cancer
pub_type：
doi：10.4048/jbc.2012.15.1.128
更新日期：2012-03-01 00:00:00
abstract：:Since recurrent bilateral breast infection due to nontuberculous mycobacterium (NTM) is rare, its diagnosis is easily overlooked; in addition, complete recovery is often difficult to achieve. We report a case of recurrent bilateral infection in a 35-year-old woman who had completed treatment for NTM. Although various ...
journal_title：Journal of breast cancer
pub_type：
doi：10.4048/jbc.2014.17.3.295
更新日期：2014-09-01 00:00:00
abstract：:[This corrects the article on p. 192 in vol. 20, PMID: 28690656.]. ...
journal_title：Journal of breast cancer
pub_type： 已发布勘误
doi：10.4048/jbc.2017.20.3.319
更新日期：2017-09-01 00:00:00
abstract：PURPOSE:To investigate the significance of the cortex-hilum (CH) area ratio and longitudinal-transverse (LT) axis ratio and the blood flow pattern for diagnosis of metastatic axillary lymph nodes by ultrasound in breast cancer patients. METHODS:From October 2005 to July 2006, we prospectively evaluated axillary nodes ...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2012.15.1.65
更新日期：2012-03-01 00:00:00
abstract：PURPOSE:In our previous studies we showed that upregulating claudin-6 (CLDN6) expression may contribute to preventing breast cancer, and that 17β-estradiol induces a concentration- and time-related effect on CLDN6 mRNA and protein expression in MCF-7 cells. However, the mechanisms of 17β-estradiol regulation of CLDN6 a...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2011.14.1.20
更新日期：2011-03-01 00:00:00
abstract：PURPOSE:We investigated the relationship between BRCA mutations and the distribution of familial cancers other than breast or ovary in high-risk breast cancer patients. METHODS:PATIENTS WITH BREAST CANCER WHO HAD AT LEAST ONE OF THE FOLLOWING RISK FACTORS WERE ENROLLED: reported family history of breast or ovarian can...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2012.15.3.283
更新日期：2012-09-01 00:00:00
abstract：PURPOSE:The role of first-line trastuzumab-based therapy has been firmly established in patients with human epidermal growth factor receptor-2 (HER2) positive metastatic breast cancer. In this trial, we evaluated the efficacy and safety of a vinorelbine and trastuzumab combination chemotherapy in patients who were pret...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2011.14.2.140
更新日期：2011-06-01 00:00:00
abstract：PURPOSE:Breast volume assessment is one of the most important steps during implant-based breast reconstruction because it is critical in selecting implant size. According to previous studies, there is a close relationship between the mastectomy specimen weight and resected breast volume. The aim of this study was to ev...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2017.20.1.98
更新日期：2017-03-01 00:00:00
abstract：:The median time of brain metastasis from the diagnosis of breast cancer is approximately 3 years. In this case report, a 69-year-old woman demonstrated cerebellar ataxia. Brain magnetic resonance imaging revealed enhanced lesions in bilateral cerebellar hemispheres. She had undergone surgery, radiation, and chemothera...
journal_title：Journal of breast cancer
pub_type：
doi：10.4048/jbc.2017.20.2.212
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:The Gail model is one of the most widely used tools to assess the risk of breast cancer. However, it is known to overestimate breast cancer risk for Asian women. Here, we validate the Gail model and the Korean model using Korean data, and subsequently update and revalidate the Korean model using recent data. M...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2014.17.3.226
更新日期：2014-09-01 00:00:00
abstract：PURPOSE:MicroRNAs (miRNAs) are a major class of small endogenous RNA molecules that posttranscriptionally regulate the expression of most genes in the human genome. miRNAs are often located in chromosomal fragile sites, which are suscept-ible to amplification or deletion. Chromosomal deletions are frequent events in br...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2016.19.2.148
更新日期：2016-06-01 00:00:00
abstract：Purpose:The treatment of triple-negative breast cancer (TNBC) remains challenging, due to the absence of estrogen, progesterone, and human epidermal growth factor receptors. This study was designed to evaluate the efficiency and safety of cytokine-induced killer (CIK) cell immunotherapy, following regular chemotherapy,...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2018.21.2.150
更新日期：2018-06-01 00:00:00
abstract：:Internationally, breast cancer is the most common female cancer, and is induced by a combination of environmental, genetic, and epigenetic risk factors. Despite the advancement of imaging techniques, invasive sampling of breast epithelial cells is the only definitive diagnostic procedure for patients with breast cance...
journal_title：Journal of breast cancer
pub_type： 杂志文章,评审
doi：10.4048/jbc.2017.20.1.12
更新日期：2017-03-01 00:00:00
abstract：:Oxygen is crucial to maintain the homeostasis in aerobic cells. Hypoxia is a condition in which cells are deprived of the oxygen supply necessary for their optimum performance. Whereas oxygen deprivation may occur in normal physiological processes, hypoxia is frequently associated with pathological conditions. It has ...
journal_title：Journal of breast cancer
pub_type： 杂志文章,评审
doi：10.4048/jbc.2019.22.e26
更新日期：2019-05-13 00:00:00
abstract：PURPOSE:The reliability of the quantitative measurement of breast density with a semi-automated thresholding method (Cumulus™) has mainly been investigated with film mammograms. This study aimed to evaluate the intrarater reproducibility of percent density (PD) by Cumulus™ with digital mammograms. METHODS:This study i...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2014.17.2.174
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:The frequency of immediate breast reconstruction (IBR) is increasing, and the types of reconstruction used are diverse. Adjuvant chemotherapy is a life-saving intervention in selected high-risk breast cancer patients. The aim of our study was to determine how IBR and type of reconstruction affect the timing of ...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2011.14.4.322
更新日期：2011-12-01 00:00:00
abstract：:Oncoplastic surgery has revolutionized the field of breast conserving surgery (BCS). The final aims of this technique are to obtain an adequate resection margin that will reduce the rate of local recurrence while simultaneously improving cosmetic outcomes. To obtain successful results after oncoplastic surgery, it is ...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2011.14.4.253
更新日期：2011-12-01 00:00:00
abstract：PURPOSE:We investigated the relationship between BRCA mutations, pathological findings, and magnetic resonance imaging (MRI) features in patients with breast cancer at risk for the mutation. METHODS:Genetic testing for BRCA mutations was performed in 275 breast cancer patients with at least one risk factor for the mut...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2013.16.3.308
更新日期：2013-09-01 00:00:00
abstract：:When faced with a case of bilateral breast cancer (BBC), understanding how to differentiate bilateral primary breast cancer from contralateral metastatic breast cancer is essential for treatment, but clear identification criteria have not been established to date. Diverse events play different roles in the therapy and...
journal_title：Journal of breast cancer
pub_type：
doi：10.4048/jbc.2019.22.e10
更新日期：2019-02-02 00:00:00
abstract：Purpose:The benefit of post-mastectomy radiation therapy (PMRT) in patients with breast cancer who achieve ypN0 following neoadjuvant chemotherapy (NAC) has not yet been established. This study aimed to identify the role of PMRT in patients who achieve ypN0 according to molecular subtype. Methods:We identified patient...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2019.22.e25
更新日期：2019-05-13 00:00:00
abstract：Purpose:The 8th edition of the American Joint Committee on Cancer (AJCC) staging manual introduced a new prognostic staging system for breast cancer. This study aimed to evaluate the changes in staging distribution and predictive power of the new staging system. Methods:Of the 12,275 patients with breast cancer identi...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2020.23.e9
更新日期：2020-01-09 00:00:00
abstract：PURPOSE:The objective of this study was to describe the evolution of health-related quality of life (HRQOL) in a cohort of breast cancer patients over 1 year after surgery and to analyse the predictive ability of HRQOL measurement instruments. METHODS:Observational, multicenter and prospective study of a cohort of bre...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2013.16.1.104
更新日期：2013-03-01 00:00:00
abstract：:ESR1 mutation is frequently encountered in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC), especially after aromatase inhibitor (AI) therapy, as a mechanism of resistance to endocrine therapy. Circulating tumor DNA-based detection of ESR1 mutatio...
journal_title：Journal of breast cancer
pub_type：
doi：10.4048/jbc.2020.23.e4
更新日期：2019-12-19 00:00:00
abstract：PURPOSE:The MammaPrint™ gene signature, currently used in clinical practice, provides prognostic information regarding the recurrence and potential metastasis in breast cancer patients. However, the prognostic information of the 70 genes included can only be estimated at the RNA expression level. In this study, we inve...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2017.20.3.246
更新日期：2017-09-01 00:00:00
abstract：Purpose:Previous oncological studies showed that lymph node ratio (LNR) (ratio of number of lymph nodes that tested positive for metastasis to the total number of lymph nodes examined) is a negative indicator of cancer survival. The American Joint Committee on Cancer (AJCC) staging system incorporates tumor size, lymph...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2018.21.e35
更新日期：2018-09-01 00:00:00
abstract：PURPOSE:This study was performed to assess frequency, timings of occurrence, and predictors of radiologic lung damage (RLD) after forward-planned intensity-modulated radiotherapy (FIMRT) for whole breast irradiation. METHODS:We retrospectively reviewed medical records of 157 breast cancer patients and each of their se...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2014.17.1.69
更新日期：2014-03-01 00:00:00
abstract：Purpose:This study was aimed at identifying the influence of initial weight and weight change during neoadjuvant chemotherapy (NAC) on pathologic complete response (pCR) and long-term survival in Chinese patients with operable breast cancer. Methods:We conducted a retrospective study using data from 409 female patient...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2019.22.e37
更新日期：2019-08-26 00:00:00
abstract：PURPOSE:Metastasis and local recurrence are the primary causes of treatment failure and patient death in breast cancer. The aim of this study was to validate a metastasis- and local recurrenceassociated biomarker for prognostic evaluation and planning treatment strategies. METHODS:Formalin-fixed, paraffin-embedded tis...
journal_title：Journal of breast cancer
pub_type： 杂志文章
doi：10.4048/jbc.2017.20.2.142
更新日期：2017-06-01 00:00:00
