Whole Exome Sequencing in the Accurate Diagnosis of Bilateral Breast Cancer: a Case Study.

abstract：PURPOSE:Re-excisions after breast-conserving surgery (BCS) for breast cancer cause delays in the adjuvant treatment, increased morbidity, and leads to poor aesthetic results. Thus, efforts to reduce the re-excision rate are essential. This study aimed to conclusively determine the re-excision rate and the factors assoc...

journal_title：Journal of breast cancer

authors： Jung W,Kang E,Kim SM,Kim D,Hwang Y,Sun Y,Yom CK,Kim SW

更新日期：2012-12-01 00:00:00

abstract：:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis belong to a severe dermatopathic spectrum that includes frequently fatal mucocutaneous manifestations consisting of whole epidermal necrosis and sloughing with bullous transformation, blistering, and further skin detachment. Notably, cancer patients are at ...

journal_title：Journal of breast cancer

authors： López-Gómez V,Yarza R,Muñoz-González H,Revilla E,Enrech S,González-Valle O,Tolosa P,Ciruelos E

更新日期：2019-09-18 00:00:00

abstract：Purpose:BRCA1/2 mutations are associated with risks of breast and ovarian cancer. In Korea, incidences of BRCA1/2 genetic testing and risk-reducing surgery (RRS) have increased with insurance coverage and the Angelina Jolie effect. The aim of this study was to identify trends in RRS performed in Korean women with the B...

journal_title：Journal of breast cancer

authors： Jung SM,Ryu JM,Park HS,Park JS,Kang E,Lee S,Lee HB,Youn HJ,Yoo TK,Kim J,Lee JE,Han SA,Kim D,Kim SW,Korean Hereditary Breast Cancer Study Group.

更新日期：2020-12-03 00:00:00

abstract：PURPOSE:Breast volume assessment is one of the most important steps during implant-based breast reconstruction because it is critical in selecting implant size. According to previous studies, there is a close relationship between the mastectomy specimen weight and resected breast volume. The aim of this study was to ev...

journal_title：Journal of breast cancer

authors： Baek WY,Byun IH,Kim YS,Lew DH,Jeong J,Roh TS

更新日期：2017-03-01 00:00:00

abstract：:Breast metastasis from gastric carcinoma is rare. We present a case of right breast mass with microcalcification in which the diagnosis of poorly differentiated adenocarcinoma from the stomach was made after a biopsy. Pleomorphic microcalcification was noted in the ill-defined breast mass, which is a rare feature in b...

journal_title：Journal of breast cancer

authors： Luk YS,Ka SY,Lo SS,Chu CY,Ma MW

更新日期：2012-09-01 00:00:00

abstract：:Internationally, breast cancer is the most common female cancer, and is induced by a combination of environmental, genetic, and epigenetic risk factors. Despite the advancement of imaging techniques, invasive sampling of breast epithelial cells is the only definitive diagnostic procedure for patients with breast cance...

journal_title：Journal of breast cancer

authors： Cheuk IW,Shin VY,Kwong A

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:This study assessed the incidence and cancer rate of probably benign lesions detected on bilateral whole-breast screening ultrasound (US), which corresponded to US Breast Imaging Reporting and Data System (BI-RADS) category 3, and evaluated the proper management of those lesions. METHODS:This study was approve...

journal_title：Journal of breast cancer

authors： Nam SY,Ko EY,Han BK,Shin JH,Ko ES,Hahn SY

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:MicroRNAs (miRNAs) are a major class of small endogenous RNA molecules that posttranscriptionally regulate the expression of most genes in the human genome. miRNAs are often located in chromosomal fragile sites, which are suscept-ible to amplification or deletion. Chromosomal deletions are frequent events in br...

journal_title：Journal of breast cancer

authors： Damavandi Z,Torkashvand S,Vasei M,Soltani BM,Tavallaei M,Mowla SJ

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:The role of first-line trastuzumab-based therapy has been firmly established in patients with human epidermal growth factor receptor-2 (HER2) positive metastatic breast cancer. In this trial, we evaluated the efficacy and safety of a vinorelbine and trastuzumab combination chemotherapy in patients who were pret...

journal_title：Journal of breast cancer

authors： Lee YR,Huh SJ,Lee DH,Yoon HH,Seol YM,Choi YJ,Kwon KA,Lee S,Oh SY,Kim SH,Kim HJ,Kwon HC

更新日期：2011-06-01 00:00:00

abstract：:Since recurrent bilateral breast infection due to nontuberculous mycobacterium (NTM) is rare, its diagnosis is easily overlooked; in addition, complete recovery is often difficult to achieve. We report a case of recurrent bilateral infection in a 35-year-old woman who had completed treatment for NTM. Although various ...

journal_title：Journal of breast cancer

authors： Yoo H,Choi SH,Kim YJ,Kim SJ,Cho YU,Choi SJ

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:We investigated the relationship between BRCA mutations, pathological findings, and magnetic resonance imaging (MRI) features in patients with breast cancer at risk for the mutation. METHODS:Genetic testing for BRCA mutations was performed in 275 breast cancer patients with at least one risk factor for the mut...

journal_title：Journal of breast cancer

authors： Noh JM,Han BK,Choi DH,Rhee SJ,Cho EY,Huh SJ,Park W,Park H,Nam SJ,Lee JE,Kil WH

更新日期：2013-09-01 00:00:00

abstract：:The median time of brain metastasis from the diagnosis of breast cancer is approximately 3 years. In this case report, a 69-year-old woman demonstrated cerebellar ataxia. Brain magnetic resonance imaging revealed enhanced lesions in bilateral cerebellar hemispheres. She had undergone surgery, radiation, and chemothera...

journal_title：Journal of breast cancer

authors： Yamada SM,Tomita Y,Shibui S,Kurokawa T,Baba Y

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:We investigated the relationship between BRCA mutations and the distribution of familial cancers other than breast or ovary in high-risk breast cancer patients. METHODS:PATIENTS WITH BREAST CANCER WHO HAD AT LEAST ONE OF THE FOLLOWING RISK FACTORS WERE ENROLLED: reported family history of breast or ovarian can...

journal_title：Journal of breast cancer

authors： Noh JM,Choi DH,Baek H,Nam SJ,Lee JE,Kim JW,Ki CS,Park W,Huh SJ

更新日期：2012-09-01 00:00:00

abstract：Purpose:The 8th edition of the American Joint Committee on Cancer (AJCC) staging manual introduced a new prognostic staging system for breast cancer. This study aimed to evaluate the changes in staging distribution and predictive power of the new staging system. Methods:Of the 12,275 patients with breast cancer identi...

journal_title：Journal of breast cancer

authors： Kim EJ,Park HS,Kim JY,Kim SI,Cho YU,Park BW

更新日期：2020-01-09 00:00:00

abstract：:We describe a patient with breast cancer who relapsed with an extensive pulmonary lymphovascular tumor embolism. A 38-year-old female, who previously received neoadjuvant chemotherapy and curative resection of breast cancer, underwent adjuvant chemotherapy and was referred to the emergency room because of sudden-onset...

journal_title：Journal of breast cancer

authors： Yang Y,Choi Y,Beom SH,Kim JW,Joen YK,Kim NJ,Kim JH,Im SA,Lee KH

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:The purpose of this study was to assess the incidence of invasive lobular carcinoma (ILC) and to compare the clinicopathological features and treatment results after breast conserving surgery (BCS) followed by radiotherapy between ILC and invasive ductal carcinoma (IDC). METHODS:A total of 1,071 patients who u...

journal_title：Journal of breast cancer

authors： Park JS,Choi DH,Huh SJ,Park W,Kim YI,Nam SJ,Lee JE,Kil WH

更新日期：2015-09-01 00:00:00

abstract：:The combination of luteinizing hormone-releasing hormone analogs (LHRHa) with tamoxifen is used as a standard postoperative adjuvant therapy in patients with hormone receptor-positive/premenopausal breast cancer. Long-acting LHRHa formulations offer advantages in terms of patient convenience. However, data on the effe...

journal_title：Journal of breast cancer

authors： Lee YJ,Wu ZY,Kim HJ,Lee JW,Chung IY,Kim J,Lee SB,Son BH,Kim SB,Jung JH,Gong G,Ahn SH,Ko B

更新日期：2020-10-26 00:00:00

abstract：:Breast cancer generally develops in older women and its incidence is continuing to increase with increasing age of the population. The pathology and biology of breast cancer seem to be different in the elderly, often resulting in the undertreatment of elderly patients and thus in higher rates of recurrence and mortal-...

journal_title：Journal of breast cancer

authors： Dimitrakopoulos FI,Kottorou A,Antonacopoulou AG,Makatsoris T,Kalofonos HP

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:The Gail model is one of the most widely used tools to assess the risk of breast cancer. However, it is known to overestimate breast cancer risk for Asian women. Here, we validate the Gail model and the Korean model using Korean data, and subsequently update and revalidate the Korean model using recent data. M...

journal_title：Journal of breast cancer

authors： Min JW,Chang MC,Lee HK,Hur MH,Noh DY,Yoon JH,Jung Y,Yang JH,Korean Breast Cancer Society.

更新日期：2014-09-01 00:00:00

abstract：Purpose:The benefit of post-mastectomy radiation therapy (PMRT) in patients with breast cancer who achieve ypN0 following neoadjuvant chemotherapy (NAC) has not yet been established. This study aimed to identify the role of PMRT in patients who achieve ypN0 according to molecular subtype. Methods:We identified patient...

journal_title：Journal of breast cancer

authors： Cho WK,Park W,Choi DH,Kim YB,Kim JH,Kim SS,Kim K,Kim JH,Ahn SJ,Lee SY,Lee J,Kim SW,Kwon J,Ahn KJ

更新日期：2019-05-13 00:00:00

abstract：PURPOSE:Surgical clips are used as a target for postoperative breast radiotherapy, and displacement of surgical clips would result in inaccurate delivery of radiation. We investigated the displacement range of surgical clips in the breast during postoperative radiotherapy following breast-conserving surgery. METHODS:A...

journal_title：Journal of breast cancer

authors： Sung S,Lee JH,Lee JH,Kim SH,Kwak YK,Lee SW,Jeon YW,Suh YJ

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:We aimed to confirm the prognostic and predictive value of p53 expression, particularly in invasive breast cancer patients, according to immunohistochemical hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) status. METHODS:Immunohistochemical data for p53, estrogen receptor, progesteron...

journal_title：Journal of breast cancer

authors： Ahn SH,Kim HJ,Han W,Cho J,Gong G,Jung KH,Kim SB,Son BH,Lee JW

更新日期：2013-12-01 00:00:00

abstract：Purpose:The aim of this study was to investigate the association of telomere length with breast cancer risk. We simultaneously explored the association between telomerase reverse transcriptase gene polymorphisms and telomere length. Methods:We used real-time quantitative polymerase chain reaction to measure relative t...

journal_title：Journal of breast cancer

authors： Wang Z,Zhang Z,Guo Y,Shui H,Liu G,Jin T,Wang H

更新日期：2018-12-01 00:00:00

abstract：:On a pathological specimen of breast cancer cells, retraction artifact during histological processing mimics true lymphovascular invasion (LVI). The accurate determination of the presence or absence of LVI is a factor in determining risk of having a positive sentinel node, or having additional positive axillary nodes ...

journal_title：Journal of breast cancer

authors： Zaorsky NG,Patil N,Freedman GM,Tuluc M

更新日期：2012-12-01 00:00:00

abstract：Purpose:Pokemon, also known as ZBTB7A, belongs to the POZ and Krüppel (POK) family of transcription repressors and is implicated in tumor progression as a key proto-oncogene. This present study aimed at determining the mechanism by which Pokemon inhibits transforming growth factor β (TGFβ)-Smad4 pathway-dependent proli...

journal_title：Journal of breast cancer

authors： Chen L,Zhong J,Liu JH,Liao DF,Shen YY,Zhong XL,Xiao X,Ding WJ,Peng XD,Xiong W,Zu XY

更新日期：2019-02-15 00:00:00

abstract：Purpose:Previous oncological studies showed that lymph node ratio (LNR) (ratio of number of lymph nodes that tested positive for metastasis to the total number of lymph nodes examined) is a negative indicator of cancer survival. The American Joint Committee on Cancer (AJCC) staging system incorporates tumor size, lymph...

journal_title：Journal of breast cancer

authors： Hung M,Xu J,Nielson D,Bounsanga J,Gu Y,Hansen AR,Voss MW

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:The frequency of immediate breast reconstruction (IBR) is increasing, and the types of reconstruction used are diverse. Adjuvant chemotherapy is a life-saving intervention in selected high-risk breast cancer patients. The aim of our study was to determine how IBR and type of reconstruction affect the timing of ...

journal_title：Journal of breast cancer

authors： Lee J,Lee SK,Kim S,Koo MY,Choi MY,Bae SY,Cho DH,Kim J,Jung SP,Choe JH,Kim JH,Kim JS,Lee JE,Yang JH,Nam SJ

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To investigate the significance of the cortex-hilum (CH) area ratio and longitudinal-transverse (LT) axis ratio and the blood flow pattern for diagnosis of metastatic axillary lymph nodes by ultrasound in breast cancer patients. METHODS:From October 2005 to July 2006, we prospectively evaluated axillary nodes ...

journal_title：Journal of breast cancer

authors： Song SE,Seo BK,Lee SH,Yie A,Lee KY,Cho KR,Woo OH,Cha SH,Kim BH

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:We investigated the feasibility of using surgical clips as markers for tumor localization and their effect on the imaging evaluation of treatment responses after neoadjuvant chemotherapy (NAC). METHODS:A total of 16 breast cancers confirmed by needle biopsy in 15 patients were included in this study from Octob...

journal_title：Journal of breast cancer

authors： Youn I,Choi SH,Kook SH,Choi YJ,Park CH,Park YL,Kim DH

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:Breast cancer subtype correlates with response to systemic therapy and overall survival (OS), but its impact on lymphatic spread is incompletely understood. In this study, we used the Surveillance, Epidemiology, and End Results registry to assess whether the subtype can predict the presence of nodal metastasis ...

journal_title：Journal of breast cancer

authors： Mattes MD,Bhatia JK,Metzger D,Ashamalla H,Katsoulakis E

更新日期：2015-06-01 00:00:00