Early-Stage Breast Cancer in the Elderly: Confronting an Old Clinical Problem.

abstract：PURPOSE:The MammaPrint™ gene signature, currently used in clinical practice, provides prognostic information regarding the recurrence and potential metastasis in breast cancer patients. However, the prognostic information of the 70 genes included can only be estimated at the RNA expression level. In this study, we inve...

journal_title：Journal of breast cancer

authors： Fatima A,Tariq F,Malik MFA,Qasim M,Haq F

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:We investigated the feasibility of using surgical clips as markers for tumor localization and their effect on the imaging evaluation of treatment responses after neoadjuvant chemotherapy (NAC). METHODS:A total of 16 breast cancers confirmed by needle biopsy in 15 patients were included in this study from Octob...

journal_title：Journal of breast cancer

authors： Youn I,Choi SH,Kook SH,Choi YJ,Park CH,Park YL,Kim DH

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:We aimed to confirm the prognostic and predictive value of p53 expression, particularly in invasive breast cancer patients, according to immunohistochemical hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) status. METHODS:Immunohistochemical data for p53, estrogen receptor, progesteron...

journal_title：Journal of breast cancer

authors： Ahn SH,Kim HJ,Han W,Cho J,Gong G,Jung KH,Kim SB,Son BH,Lee JW

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:The Gail model is one of the most widely used tools to assess the risk of breast cancer. However, it is known to overestimate breast cancer risk for Asian women. Here, we validate the Gail model and the Korean model using Korean data, and subsequently update and revalidate the Korean model using recent data. M...

journal_title：Journal of breast cancer

authors： Min JW,Chang MC,Lee HK,Hur MH,Noh DY,Yoon JH,Jung Y,Yang JH,Korean Breast Cancer Society.

更新日期：2014-09-01 00:00:00

abstract：Purpose:Pokemon, also known as ZBTB7A, belongs to the POZ and Krüppel (POK) family of transcription repressors and is implicated in tumor progression as a key proto-oncogene. This present study aimed at determining the mechanism by which Pokemon inhibits transforming growth factor β (TGFβ)-Smad4 pathway-dependent proli...

journal_title：Journal of breast cancer

authors： Chen L,Zhong J,Liu JH,Liao DF,Shen YY,Zhong XL,Xiao X,Ding WJ,Peng XD,Xiong W,Zu XY

更新日期：2019-02-15 00:00:00

abstract：PURPOSE:Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel belonging to the transient receptor potential family, and it is expressed in different neoplastic tissues. Its activation is associated with regulation of cancer growth and progression. The aim of this research was to study the ex...

journal_title：Journal of breast cancer

authors： Vercelli C,Barbero R,Cuniberti B,Racca S,Abbadessa G,Piccione F,Re G

更新日期：2014-12-01 00:00:00

abstract：:The Korean Breast Cancer Society (KBCS) has reported a nationwide breast cancer data since 1996. We present a comprehensive report on the facts and trends of breast cancer in Korea in 2013. Data on the newly diagnosed patients in the year 2013 were collected from 99 hospitals by using nationwide questionnaire survey. ...

journal_title：Journal of breast cancer

authors： Min SY,Kim Z,Hur MH,Yoon CS,Park EH,Jung KW,Korean Breast Cancer Society Consortium.

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:This study was performed to assess frequency, timings of occurrence, and predictors of radiologic lung damage (RLD) after forward-planned intensity-modulated radiotherapy (FIMRT) for whole breast irradiation. METHODS:We retrospectively reviewed medical records of 157 breast cancer patients and each of their se...

journal_title：Journal of breast cancer

authors： Kim H,Bae H,Lee MY,Cheong KH,Kim KJ,Han T,Kang SK,Park S,Hwang T,Yoon JW,Kim LS

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:Breast cancer subtype correlates with response to systemic therapy and overall survival (OS), but its impact on lymphatic spread is incompletely understood. In this study, we used the Surveillance, Epidemiology, and End Results registry to assess whether the subtype can predict the presence of nodal metastasis ...

journal_title：Journal of breast cancer

authors： Mattes MD,Bhatia JK,Metzger D,Ashamalla H,Katsoulakis E

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:Patients with recurrent breast cancer usually die of their disease, even after radical surgery and adjuvant therapies which could reduce the odds of dying. Many studies analyzed and compared patients who died of recurrent disease with those that died without recurrent disease. However, less attention has been p...

journal_title：Journal of breast cancer

authors： Song WJ,Kim KI,Park SH,Kwon MS,Lee TH,Park HK,An JS

更新日期：2012-06-01 00:00:00

abstract：Purpose:Whether tamoxifen affects the risk of neurodegenerative disease is controversial. This nationwide population-based study investigated the risk of Parkinson's disease (PD) associated with tamoxifen treatment in female patients with breast cancer using Taiwan's National Health Insurance Research Database. Method...

journal_title：Journal of breast cancer

authors： Hong CT,Chan L,Hu CJ,Lin CM,Hsu CY,Lin MC

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:In our previous studies we showed that upregulating claudin-6 (CLDN6) expression may contribute to preventing breast cancer, and that 17β-estradiol induces a concentration- and time-related effect on CLDN6 mRNA and protein expression in MCF-7 cells. However, the mechanisms of 17β-estradiol regulation of CLDN6 a...

journal_title：Journal of breast cancer

authors： Yafang L,Qiong W,Yue R,Xiaoming X,Lina Y,Mingzi Z,Ting Z,Yulin L,Chengshi Q

更新日期：2011-03-01 00:00:00

abstract：:The prognosis associated with brain metastasis arising from breast cancer is very poor. Eribulin is a microtubule dynamic inhibitor synthesized from halichondrin B, a natural marine product. In a phase III study (EMBRACE), eribulin improved overall survival in patients with heavily pretreated metastatic breast cancers...

journal_title：Journal of breast cancer

authors： Byun KD,Ahn SG,Baik HJ,Lee A,Bae KB,An MS,Kim KH,Shin JH,Park HK,Cho H,Jeong J,Kim TH

更新日期：2016-06-01 00:00:00

abstract：Purpose:Previous oncological studies showed that lymph node ratio (LNR) (ratio of number of lymph nodes that tested positive for metastasis to the total number of lymph nodes examined) is a negative indicator of cancer survival. The American Joint Committee on Cancer (AJCC) staging system incorporates tumor size, lymph...

journal_title：Journal of breast cancer

authors： Hung M,Xu J,Nielson D,Bounsanga J,Gu Y,Hansen AR,Voss MW

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:The purpose of this study was to assess the incidence of invasive lobular carcinoma (ILC) and to compare the clinicopathological features and treatment results after breast conserving surgery (BCS) followed by radiotherapy between ILC and invasive ductal carcinoma (IDC). METHODS:A total of 1,071 patients who u...

journal_title：Journal of breast cancer

authors： Park JS,Choi DH,Huh SJ,Park W,Kim YI,Nam SJ,Lee JE,Kil WH

更新日期：2015-09-01 00:00:00

abstract：:On a pathological specimen of breast cancer cells, retraction artifact during histological processing mimics true lymphovascular invasion (LVI). The accurate determination of the presence or absence of LVI is a factor in determining risk of having a positive sentinel node, or having additional positive axillary nodes ...

journal_title：Journal of breast cancer

authors： Zaorsky NG,Patil N,Freedman GM,Tuluc M

更新日期：2012-12-01 00:00:00

abstract：:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis belong to a severe dermatopathic spectrum that includes frequently fatal mucocutaneous manifestations consisting of whole epidermal necrosis and sloughing with bullous transformation, blistering, and further skin detachment. Notably, cancer patients are at ...

journal_title：Journal of breast cancer

authors： López-Gómez V,Yarza R,Muñoz-González H,Revilla E,Enrech S,González-Valle O,Tolosa P,Ciruelos E

更新日期：2019-09-18 00:00:00

abstract：PURPOSE:As doxorubicin cardiotoxicity is considered irreversible, early detection of cardiotoxicity and prevention of overt heart failure is essential. Although there are monitoring guidelines for cardiotoxicity, optimal timing for early detection of subclinical doxorubicin cardiotoxicity is still obscure. The purpose ...

journal_title：Journal of breast cancer

authors： Chung WB,Yi JE,Jin JY,Choi YS,Park CS,Park WC,Song BJ,Youn HJ

更新日期：2013-06-01 00:00:00

abstract：Purpose:We aimed to investigate the clinicopathologic factors associated with distant metastasis (DM) and post-recurrence overall survival (OS) after salvage treatments for isolated locoregional recurrence (ILRR) of breast cancer and identify long-term surviving patients for providing a more personalized therapy. Meth...

journal_title：Journal of breast cancer

authors： Kim BH,Shin KH,Chie EK,Kim JH,Kim K,Hwang KT,Kim J,Choi IS,Park JH,Kim S

更新日期：2020-04-29 00:00:00

abstract：Purpose:Triple-negative breast cancer (TNBC) is associated with poor prognosis with limited treatment options. Angiogenesis is known to be involved in the progression of TNBC, and targeting this pathway results in modest clinical benefits. In this study, we analyzed the role of tumor microvascular endothelial Notch1 (E...

journal_title：Journal of breast cancer

authors： Kim D,Lee J,Kang J,Kim SH,Yoo TK,Oh S,Lee A

更新日期：2019-12-12 00:00:00

abstract：Purpose:The 8th edition of the American Joint Committee on Cancer (AJCC) staging manual introduced a new prognostic staging system for breast cancer. This study aimed to evaluate the changes in staging distribution and predictive power of the new staging system. Methods:Of the 12,275 patients with breast cancer identi...

journal_title：Journal of breast cancer

authors： Kim EJ,Park HS,Kim JY,Kim SI,Cho YU,Park BW

更新日期：2020-01-09 00:00:00

abstract：PURPOSE:To investigate the significance of the cortex-hilum (CH) area ratio and longitudinal-transverse (LT) axis ratio and the blood flow pattern for diagnosis of metastatic axillary lymph nodes by ultrasound in breast cancer patients. METHODS:From October 2005 to July 2006, we prospectively evaluated axillary nodes ...

journal_title：Journal of breast cancer

authors： Song SE,Seo BK,Lee SH,Yie A,Lee KY,Cho KR,Woo OH,Cha SH,Kim BH

更新日期：2012-03-01 00:00:00

abstract：Purpose:The treatment of triple-negative breast cancer (TNBC) remains challenging, due to the absence of estrogen, progesterone, and human epidermal growth factor receptors. This study was designed to evaluate the efficiency and safety of cytokine-induced killer (CIK) cell immunotherapy, following regular chemotherapy,...

journal_title：Journal of breast cancer

authors： Li M,Wang Y,Wei F,An X,Zhang N,Cao S,Ren B,Zhang X,Ren X

更新日期：2018-06-01 00:00:00

abstract：Purpose:The aim of this study was to investigate the association of telomere length with breast cancer risk. We simultaneously explored the association between telomerase reverse transcriptase gene polymorphisms and telomere length. Methods:We used real-time quantitative polymerase chain reaction to measure relative t...

journal_title：Journal of breast cancer

authors： Wang Z,Zhang Z,Guo Y,Shui H,Liu G,Jin T,Wang H

更新日期：2018-12-01 00:00:00

abstract：Purpose:The exact mechanism regulating fibronectin (FN) expression in breast cancer cells has not been fully elucidated. In this study, we investigated the pharmacological mechanism of berberine (BBR) with respect to FN expression in triple-negative breast cancer (TNBC) cells. Methods:The clinical significance of FN m...

journal_title：Journal of breast cancer

authors： Jeong Y,You D,Kang HG,Yu J,Kim SW,Nam SJ,Lee JE,Kim S

更新日期：2018-03-01 00:00:00

abstract：Purpose:BRCA1/2 mutations are associated with risks of breast and ovarian cancer. In Korea, incidences of BRCA1/2 genetic testing and risk-reducing surgery (RRS) have increased with insurance coverage and the Angelina Jolie effect. The aim of this study was to identify trends in RRS performed in Korean women with the B...

journal_title：Journal of breast cancer

authors： Jung SM,Ryu JM,Park HS,Park JS,Kang E,Lee S,Lee HB,Youn HJ,Yoo TK,Kim J,Lee JE,Han SA,Kim D,Kim SW,Korean Hereditary Breast Cancer Study Group.

更新日期：2020-12-03 00:00:00

abstract：:[This corrects the article on p. 192 in vol. 20, PMID: 28690656.]. ...

journal_title：Journal of breast cancer

authors： Chu AJ,Chang JM,Cho N,Moon WK

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:We evaluated the effect of local recurrence (LR) and regional recurrence (RR) on distant metastasis and survival in patients treated with breast conservation therapy (BCT). METHODS:We analyzed 907 patients who were treated for invasive breast cancer between 1993 and 2006. With 53 months of follow-up, 28 patien...

journal_title：Journal of breast cancer

authors： Lee JS,Kim SI,Park HS,Lee JS,Park S,Park BW

更新日期：2011-09-01 00:00:00

abstract：:Internationally, breast cancer is the most common female cancer, and is induced by a combination of environmental, genetic, and epigenetic risk factors. Despite the advancement of imaging techniques, invasive sampling of breast epithelial cells is the only definitive diagnostic procedure for patients with breast cance...

journal_title：Journal of breast cancer

authors： Cheuk IW,Shin VY,Kwong A

更新日期：2017-03-01 00:00:00

abstract：Purpose:Breast cancer treatments, including chemotherapy, administered in combination with glucocorticoids can induce hyperglycemia. This study aimed to investigate the effect of hyperglycemia during adjuvant chemotherapy on the prognosis of breast cancer patients without a known history of diabetes. Methods:In this s...

journal_title：Journal of breast cancer

authors： Ahn HR,Kang SY,Youn HJ,Jung SH

更新日期：2020-08-05 00:00:00