解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVE:To report conservative and surgical strategies for treatment of mesh erosion after pelvic organ prolapse (POP) repair. METHODS:Between 1998 and 2008, 179 patients underwent integral pelvic floor reconstruction for advanced POP in our tertiary urogynecological unit. Patients' charts and follow-up data were en...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000324243
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:Endorectal coil MRI (endoMRI) of the prostate is useful to evaluate tumor localization. There is little evidence on patient characteristics affecting its diagnostic performance. We evaluate the influence of clinical and histological parameters on the accuracy of endoMRI. METHODS:Sixty-nine patients with pro...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000324098
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:The initial objective of this renal cancer study was to identify gene sets in clear cell renal cell carcinoma (ccRCC) to support grading of ccRCC histopathology. MATERIALS AND METHODS:Preselected ccRCC tumor tissues of grade 1 (G1, n = 14) and grade 3 (G3, n = 15) as well es 14 normal kidney tissues thereof ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000328196
更新日期:2011-01-01 00:00:00
abstract::Metastatic renal cell carcinoma (mRCC) is a difficult to treat malignancy and currently Sunitinib is a standard of care first-line therapy. A new metastasis during the treatment is considered a sign of drug failure and alternative therapeutic methods should be tried. Here, we report 2 cases of newly diagnosed isolated...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000321908
更新日期:2011-01-01 00:00:00
abstract:AIM:To examine the hypothesis that the risk of high-grade bladder cancer can be predicted using noninvasively obtained data. PATIENTS AND METHODS:We retrospectively analyzed the database of 431 patients that had transurethral resection of first-time bladder tumors between June 1998 and December 2009. Pre-operative par...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000328635
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To investigate the diagnostic value of the nuclear matrix protein 22 (NMP22) test in comparison to urine cytology for the detection of upper tract urothelial carcinoma. PATIENTS AND METHODS:Patients with transitional cell carcinoma of the upper urinary tract (n = 34) and patients with renal calculosis (n = 2...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000330246
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine whether periurethral injection of allogenic mesenchymal stem cells (MSCs) could increase the leak point pressure (LPP) in a rat model of stress urinary incontinence. MATERIALS AND METHODS:Female Sprague-Dawley rats (230-240 g, n = 30) were divided into 3 groups: sham ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000317322
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Sunitinib is standard first-line therapy for metastatic clear cell renal cancer (MCRC). It is associated with leucopenia; however, its effects on specific immune cell subsets are unclear. Alterations in immune cell subsets may contribute to tumour progression. METHODS:Lymphocyte subsets (CD3, 4, 8, 19 and 5...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章
doi:10.1159/000319498
更新日期:2011-01-01 00:00:00
abstract::A review of the recent literature on the surgical management of anterior urethral stricture was performed. The literature was searched via PubMed using the search terms 'urethral stricture' and 'urethroplasty' from 1996 to 2009. The management of anterior urethral strictures is changing rapidly in the sense that the r...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000319501
更新日期:2011-01-01 00:00:00
abstract::Laparoscopic partial nephrectomy (LPN) is increasingly becoming a definitive therapeutic option for the treatment of small (less than 4 cm) and select moderate-sized (less than 7 cm) renal tumors. Postoperative hemorrhage and urine leak are the most pertinent complications after nephron-sparing surgery, open or laparo...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000331905
更新日期:2011-01-01 00:00:00
abstract::We investigated the baseline levels of urine nuclear matrix protein 22 (U-NMP22) and survivin in urine after radical cystectomy for primary invasive bladder cancer. We measured U-NMP22 and survivin values in 72 patients with four types of urinary diversion (Indiana bladder, Bricker bladder, Mainz bladder and orthotopi...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000330911
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:The regulation proteins retinoblastoma protein (pRb) and p16 play an important role in the cell cycle as tumor suppressors. pRb is the main substrate for the function of cyclin-dependent kinases during the cell cycle in the transition from G(1) to S phase. In this study, the immunohistochemical expression ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000320510
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Phosphatidylinositol 3-kinase (PI3K)-AKT signaling is a well-characterized pathway involved in the control of cell proliferation, apoptosis and oncogenesis. LY294002 is a commonly used pharmacologic inhibitor which acts at the ATP-binding site of the PI3K enzyme, thus selectively inhibiting the PI3K-AKT nexu...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000322849
更新日期:2011-01-01 00:00:00
abstract::Acute renal failure due to ischemia-reperfusion (I/R) injury is a common complication in cardiovascular surgery. We determined the influence of tadalafil on renal injury in a renal I/R model in rats. For this purpose, 21 male Wistar albino rats were separated into 3 groups: sham, placebo and tadalafil. A right nephrec...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000321927
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Prostate biopsy (PBx) techniques have changed significantly since the original Hodge's scheme, with an increase in the number and location of cores. These improvements have been realized in part because of the introduction of different local anaesthesia techniques. We critically analysed the literature discu...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000327827
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Adherence to international guidelines is viewed as a prerequisite for optimal medical care delivery. Previously reported surveys for non-muscle-invasive bladder cancer (NMIBC) employed mailed questionnaires to urologists or patients resulting in conflicting degrees of agreement with existing guidelines. In...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000321926
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Virtual reality (VR) simulation has been known to shorten learning curves. The aim of this research was to determine whether VR transurethral bladder tumor resection (TURBT) with and without photodynamic diagnostic (PDD) can improve endourological skills in novice and trained endoscopists. MATERIALS AND M...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000328218
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To assess the association between the development of a urethral stricture (US) and disease-free survival for patients with localized prostate cancer treated with high-intensity focused ultrasound (HIFU). PATIENTS AND METHODS:Patients with clinical stage T1-T2N0M0 prostate cancer were eligible for treatment wit...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000330909
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study is to clarify the relationship of erectile dysfunction (ED) and diabetes mellitus (DM) parameters (referred to with '1'), including peripheral neuropathy (referred to with '2'). METHODS:(1) The DM parameters including age, serum levels of blood sugar, hemoglobin A1c, duration of DM a...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000327991
更新日期:2011-01-01 00:00:00
abstract::This is the first report of urothelial carcinoma (UC) in a hemodialysis (HD) patient treated with almost the same doses of gemcitabine and paclitaxel (GP) as those administered to patients with normal renal function. There have been some reports of UC treated with cisplatin-based chemotherapy in HD patients. However, ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000327511
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:Genetic variants of vitamin D receptor (VDR) were implicated in urolithiasis susceptibility in several case-control studies. However, these studies so far have provided conflicting results. In order to investigate the potential relationship, a meta-analysis was conducted. METHODS:Eligible studies were retrie...
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000323949
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The objective of this study is to describe and analyze the experience over a period of 10 years at our center through a retrospective study of a series of diagnosed and treated cases of penile fracture. MATERIAL AND METHODS:From 2005 to 2009 the Urology Department of the Hospital Clínico San Carlos of Madri...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000324249
更新日期:2011-01-01 00:00:00
abstract::This report presents a case of a 16-year-old hypertensive boy who presented to our clinic. Laboratory findings showed severe hypokalemia and markedly increased plasma renin activity. Abdominal ultrasonography and contrast-enhanced computed tomography of the abdomen revealed a well-circumscribed, solid, hypoenhancing c...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000314339
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Wnt-1 is capable of inducing metanephric mesenchyme to undergo tubulogenesis. A relationship between the degree of cystogenesis and reduced E-cadherin (E-cad) expression was described. Syndecan-1 (Sdc-1) has a critical role in kidney development. MATERIALS AND METHODS:Ten multicystic dysplastic kidneys (M...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000296285
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Planification of living donor nephrectomy requires exact knowledge of the renal vascular architecture because of the high prevalence of anatomical variants. After magnetic resonance angiography (MRA) challenged CT angiography for preoperative assessment over the last years, we revisit in this study the rel...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000273467
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:To investigate the protective role of thymoquinone (TQ) on unilateral testicular ischemia-reperfusion (I/R) injury in mice. MATERIALS AND METHODS:Experiments were performed on male C57BL/6 mice (8 weeks old, 20-25 g). The animals were divided into 3 groups including 6 mice in each group: control (sham), tor...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000318890
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Radical prostatectomy (RP) in patients with locally advanced (cT3) prostate cancer (PCa) is considered an optional therapy. AIM:To evaluate outcomes of surgery for cT3 disease and to compare results with those of patients treated for cT1-T2 PCa. PATIENTS AND METHODS:Data of 74 consecutive patients with c...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000316944
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Our purpose was to evaluate patients who underwent failed hypospadias repair. PATIENTS AND METHODS:We evaluated 4 different groups of patients who underwent failed hypospadias repair. Group 1: patients who underwent only urethral surgery; group 2: patients who underwent only corpora cavernosa surgery; gro...
journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
doi:10.1159/000319856
更新日期:2010-01-01 00:00:00
abstract:AIMS:To study the effects of left gonadal vein ligation on semen parameters and venous hemodynamics of the testis. SUBJECTS AND METHODS:All male voluntary kidney donors who were scheduled to have left donor nephrectomy between March 2004 and February 2005, by either open or laparoscopic technique, were considered for ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000277603
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To present the long-term outcome of high-risk prostate cancer patients treated by radical retropubic prostatectomy (RRP) and stage-dependent adjuvant androgen deprivation therapy. PATIENTS AND METHODS:Between 1989 and 2005, 2,655 patients underwent RRP by 9 surgeons. All cases (n = 372) with high-risk prostate...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000277593
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Cyclooxygenase-2 (COX-2) is a key enzyme involved in the production of prostaglandins and its inhibitors have been shown to induce apoptosis in a variety of cancer cells. We reasoned that combination treatment of renal cell carcinoma (RCC) cells with COX-2 inhibitors and anticancer agents may result in syner...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000288243
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:We report our experience with the use of povidone iodine instillation into the renal pelvis for the treatment of chyluria. MATERIALS AND METHODS:From August 2006 to November 2008, 26 patients with chyluria were treated. There were 18 males and 8 females ranging from 24-55 years of age. Cystoscopic localization...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000288233
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:The aim of this work was to verify the tolerability and the preliminary clinical results of intensive intravesical instillations of a mitomycin C (MMC) regimen. PATIENTS AND METHODS:From September 2007 to November 2009, 40 consecutive evaluable patients with pathologically confirmed intermediate-risk non-mus...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000315492
更新日期:2010-01-01 00:00:00
abstract::The overactive bladder syndrome (OAB) negatively affects the daily life of many people. Conservative treatments, such as antimuscarinics, do not always lead to sufficient improvement of the complaints and/or are often associated with considerable side effects resulting in treatment failure. In the case of failure or i...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000288223
更新日期:2010-01-01 00:00:00
abstract:AIM:Since DNA damage-related apoptosis is raising concerns regarding abnormal spermatogenesis, we investigated the changes in γ-H2AX during testicular germ cell apoptotic responses in the varicocele model. MATERIALS AND METHODS:Varicocele was induced by partial ligation of the left renal vein and animals were sacrific...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000316356
更新日期:2010-01-01 00:00:00
abstract:AIM:To analyze demographics, perioperative mortality and overall survival of radical cystectomy (RC) in patients aged 70+ years in Austria in a nation-wide registry cohort. PATIENTS AND METHODS:All patients >69 years who underwent RC in public hospitals (covering >95% of all surgical procedures) in Austria between 199...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000316100
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:Improvements in quality of life (QoL) and disease-related symptoms are key goals in the treatment of hormone refractory prostate cancer (HRPC). Our aim was to evaluate the impact of gefitinib on QoL of patients with HRPC. METHODS:Patients with HRPC received gefitinib 250 mg daily in addition to antiandrogen...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000200800
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:The goal of the study was to define treatment rules for the uncommon, rarely (10%) malignant and chemorefractory Leydig cell tumors (LCT) of the testis. METHODS:The main clinical data of patients treated in centers affiliated to the GUONE (North-Eastern Uro-Oncological Group, Italy) were reviewed. We cons...
journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
doi:10.1159/000200790
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:This prospective study was designed to compare symmetrical overlapping double flaps with a single dartos flap in regard to fistula formation as an adjunct to tubularized incised plate urethroplasty (TIPU). PATIENTS AND METHODS:77 consecutive children with primary coronal or subcoronal hypospadias were ran...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000241682
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:Our aim was to review our pathological archive to find out the actual incidence of micropapillary pattern (MPP) in our urothelial carcinoma patient population and determine its correlation with clinical outcome. PATIENTS AND METHODS:14 out of 170 cases with complete clinical follow-up were clinicopathologic...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000241672
更新日期:2009-01-01 00:00:00