Current information on sacral neuromodulation and botulinum toxin treatment for refractory idiopathic overactive bladder syndrome: a review.

Abstract:

:The overactive bladder syndrome (OAB) negatively affects the daily life of many people. Conservative treatments, such as antimuscarinics, do not always lead to sufficient improvement of the complaints and/or are often associated with considerable side effects resulting in treatment failure. In the case of failure or intolerable side effects, sacral neuromodulation (SNM) and botulinum toxin are minimally invasive and reversible alternatives. Currently, of these alternatives only SNM with InterStimTM therapy has FDA approval for use in OAB patients. This review attempts to provide an update on the current position of SNM and botulinum toxin in the second-line management of adults with idiopathic OAB, based on the available clinical evidence concerning the efficacy and safety.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Leong RK,De Wachter SG,van Kerrebroeck PE

doi

10.1159/000288223

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

245-53

issue

3

eissn

0042-1138

issn

1423-0399

pii

000288223

journal_volume

84

pub_type

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