Management of a new isolated metastasis during sunitinib treatment in renal cell carcinoma patients: a lesson from two cases.

Abstract:

:Metastatic renal cell carcinoma (mRCC) is a difficult to treat malignancy and currently Sunitinib is a standard of care first-line therapy. A new metastasis during the treatment is considered a sign of drug failure and alternative therapeutic methods should be tried. Here, we report 2 cases of newly diagnosed isolated metastasis during Sunitinib treatment of mRCC patients. Our management plan included local palliative therapy to the lesion followed by recommencing of Sunitinib. This resulted in a good symptomatic relief locally as well as good overall control of the disease.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Shablak A,O'Dwyer J,Hawkins R,Board R

doi

10.1159/000321908

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

245-8

issue

2

eissn

0042-1138

issn

1423-0399

pii

000321908

journal_volume

86

pub_type

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