The inhibitory activity of some citrate analogues upon calcium crystalluria: observations using an improved urine evaporation technique.

Abstract:

:The ability of three compounds, all similar in chemical structure to citric acid, to decrease calcium crystalluria has been measured. The measurements were made in normal human urine at 37 degrees C and compared with the crystal-decreasing power of citric acid when measured in the same way and in the same urine samples. One of the compounds tested, phosphocitric acid, was more potent than citric acid in inhibiting calcium oxalate crystal precipitation. At higher concentrations it also proved more effective against calcium phosphate. A urine evaporation method was used to carry out the crystal inhibition tests after modification to improve its precision.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Hallson PC,Kasidas GP,Samuell CT

doi

10.1159/000282875

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

43-7

issue

1

eissn

0042-1138

issn

1423-0399

journal_volume

57

pub_type

杂志文章
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