Abstract:
PURPOSE:The purpose of this study was to determine whether periurethral injection of allogenic mesenchymal stem cells (MSCs) could increase the leak point pressure (LPP) in a rat model of stress urinary incontinence. MATERIALS AND METHODS:Female Sprague-Dawley rats (230-240 g, n = 30) were divided into 3 groups: sham operation (group C), saline-treated (group S) and MSC-treated (group M). Bilateral pudendal nerve dissection followed by normal saline or MSC injection on both sides of the urethra was done. LPP and closing pressure (CP) testing was performed after the treatment. The specific markers for smooth muscle cells in the transplantation sites of the urethra were determined. RESULTS:Both the LPP and CP were significantly lower in group S than controls. However, these were restored to the control values in group M (p < 0.05). The LPPs of groups C, S and M were 29.1 ± 2.1, 22.0 ± 2.2 and 43.1 ± 3.2 cm H(2)O, respectively. The CPs of groups C, S and M were 27.1 ± 3.1, 21.1 ± 3.2, and 32.1 ± 2.1 cm H(2)O, respectively. The injected MSCs stained positive for muscle-specific markers. CONCLUSION:This study suggests that MSCs might differentiate into muscle lineage cells and may contribute to the repair of damaged muscle tissue.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Kim SO,Na HS,Kwon D,Joo SY,Kim HS,Ahn Ydoi
10.1159/000317322subject
Has Abstractpub_date
2011-01-01 00:00:00pages
110-6issue
1eissn
0042-1138issn
1423-0399pii
000317322journal_volume
86pub_type
杂志文章abstract:INTRODUCTION:The purpose of this study was to evaluate prognostic factors for patients with upper urinary tract urothelial carcinoma (UUT-UC) after nephroureterectomy and to seek a better way of finding more favorable clinical results for these patients. PATIENTS AND METHODS:We retrospectively reviewed the medical rec...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000335274
更新日期:2012-01-01 00:00:00
abstract::Intrarenal blood flow distribution was measured in normal and hypoperfused dog kidneys by xenon-133 washout measurement in one kidney vary slightly in contrast to those done in different kidneys. In normal kidneys the ratio of compartment I (CI) flow to whole renal flow -- i.e., the CI fraction--as measured by the xen...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280818
更新日期:1982-01-01 00:00:00
abstract::Radiotherapy (RT) is applied in prostate cancer patients with a biochemical recurrence (BcR) after radical prostatectomy (RP). However, for the patients with persistent PSA but not undergoing the process of BcR, it remains unknown whether the application of RT can exempt them from the upcoming BcR. In this study, we i...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000488536
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate the role of bone scan as a staging investigation in newly diagnosed untreated prostate cancers. MATERIALS AND METHODS:Bone scan results in patients with newly diagnosed prostate cancer were reviewed and correlated with clinical stage, prostate-specific antigen (PSA) and Gleason s...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000091620
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:To review the incidence of healthcare-associated infections/urinary tract infection (UTI), risk factors, microorganisms isolated and antibiotic resistances in patients who underwent lower urinary tract endoscopic surgery (LUTES) in a tertiary care hospital. METHODS:A prospective observational study was carr...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000488251
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The internet is an emerging source of information for prostate cancer (PCa) patients. Since little is known about the quality of information on PCa provided online, we investigated its accordance to the latest European Association of Urology (EAU) guidelines. METHODS:A total of 89 German web pages were incl...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000487146
更新日期:2018-01-01 00:00:00
abstract::We report here a 70-year-old man with prostatic malacoplakia which is an extremely rare disease. This diagnosis was obtained from histological examination by prostatic biopsy because the patient was suspected having prostatic cancer on digital examination. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281024
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:To describe our surgical experience and clinical outcome in laparoscopic radical nephrectomy (LRN) for renal cell carcinoma (RCC) with level 1 renal vein tumor thrombus. PATIENTS AND METHODS:11 patients with RCC level 1 renal vein tumor thrombus were treated by LRN plus thrombectomy. The mean age was 66.8 ye...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000363580
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Urologists have to master a variety of techniques to be able to offer the most appropriate surgical stone treatment for each individual patient. Therefore, we performed a survey among board-certified Swiss urologists to assess the availability of the different surgical methods, the current practices of sur...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000502806
更新日期:2019-01-01 00:00:00
abstract::Urinary incontinence in 80 men was classifed by combined radiological and urodynamic techniques. 28 cases of pure stress incontinence were evaluated for grading of sphincteric loss. Clinical and sphincterometric data were correlated. Functional urethral length, urethral closure pressure at rest and with voluntary sphi...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280348
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Despite advances in immunosuppressant medications, improvement in long-term survival for kidney transplant recipients has been more difficult to achieve. In fact, the number of patients with failing grafts who must either return to dialysis or undergo a second transplant is increasing. Second transplantation...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000499490
更新日期:2019-01-01 00:00:00
abstract::Renal pseudoaneurysms are a well-documented complication following trauma or after percutaneous biopsy. When symptomatic, patients present with hematuria and deteriorating renal function. We present the case of a 62-year-old man who, due to development of a pseudoaneurysm, presented with gross hematuria 10 days after ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030536
更新日期:2000-01-01 00:00:00
abstract:INTRODUCTION:The role of positron emission tomography (PET) with 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) is currently under evaluation in urologic oncology. The aim of the present study was to investigate the use of [18F]FDG positron emission tomography ([18F]FDG-PET) in the detection and treatment control of malign...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000048442
更新日期:2002-01-01 00:00:00
abstract:INTRODUCTION:Currently, surgical repair for vesicovaginal fistula (VVF) provides excellent results, but the recurrent VVF is difficult to treat as compared to primary. PATIENTS AND METHODS:Sixty-eight patients (44 primipara and 24 multipara) with recurrent VVF repair from January 2002 to December 2007 were included in...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000331503
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:To present the incidence of bacterial colonization on ureteral double J stents (DJS); isolate the uropathogens; define the rate of multi-resistant bacteria strains (MRBS) and present their clinical importance.
MATERIALS AND METHODS:
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000486798
更新日期:2018-01-01 00:00:00
abstract::Both under physiologic conditions and after short-term ischemia (1-3 min) kallikrein and locally synthesized prostaglandins contribute to control renal blood flow. In the present experiment the antiproteases aprotinin and gabexate-mesilate were administered to rabbits in an attempt to show whether the hemodynamic chan...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280880
更新日期:1983-01-01 00:00:00
abstract:INTRODUCTION:The aims of this study were to establish the prevalence of enuresis, to determine accompanying factors, and to identify common methods in the management of enuresis in Turkish children aged between 6 and 11 years living in eastern Anatolia. METHODS:The parents of 3,527 schoolchildren aged between 6 and 11...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000079696
更新日期:2004-01-01 00:00:00
abstract::Metastatic renal cell carcinoma (mRCC) is a difficult to treat malignancy and currently Sunitinib is a standard of care first-line therapy. A new metastasis during the treatment is considered a sign of drug failure and alternative therapeutic methods should be tried. Here, we report 2 cases of newly diagnosed isolated...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000321908
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The bladder is the most common affected site in urinary tract endometriosis, being diagnosed during gynecologic follow-up. The surgical urological treatment might lead to good results. STUDY OBJECTIVE:To define the state of the art in the diagnosis and treatment of bladder endometriosis. METHODS:We perform...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000339519
更新日期:2012-01-01 00:00:00
abstract::The objective of this case report is to present a rare bladder tumour in a young patient 25 years after the treatment with cyclophosphamide because of a neuroblastoma of the right eye. The first symptom of the tumour was macroscopic haematuria with dysuria and pollakiuria. The final diagnosis was dictaminated by the p...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000437442
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:MicroRNA (miR)371a-3p was suggested to be a sensitive and specific new serum biomarker of germ cell tumours (GCTs); however, its clinical usefulness remains unproven. PATIENTS, METHODS:In 312 consecutive cases with various testicular diseases, serum levels of miR371a-3p were measured. Measurement results ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000477446
更新日期:2017-01-01 00:00:00
abstract::The first case of carcinosarcoma in the spermatic cord is reported in a 40-year-old man. The tumor was a 2.5 X 2 cm pseudoencapsulated formation located in the connective tissue of the spermatic cord among the blood vessels. Light microscopy examination of the neoplasm revealed two different histological patterns: epi...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281727
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:Many epidemiological and experimental studies report a strong role of chemical carcinogens in the etiology of bladder cancer. However, involvement of trace elements in the tumorigenesis of transitional cell carcinoma of the bladder has been poorly investigated. The aim of this study was to examine the rela...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000341976
更新日期:2012-01-01 00:00:00
abstract::Sex-dependent stone formation following portacaval shunt (PCS) was investigated in 82 male and 71 female Sprague-Dawley rats. 72.6% of male PCS rats and none of the female PCS rats developed urolithiasis, in 90.2%, potassium-hydrogen-urate stones formed. Hormonal analysis revealed significant alterations in steroid ho...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282544
更新日期:1993-01-01 00:00:00
abstract:AIM:To evaluate outcomes of laparoscopic adrenalectomy (LA) and laparoendoscopic single-site surgery (LESS) for adrenal masses in the light of changing laparoscopic surgical techniques. MATERIALS AND METHODS:Seventy-three patients were analyzed retrospectively. There were 2 groups; group 1 included patients who had co...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000351959
更新日期:2013-01-01 00:00:00
abstract::In an acute rat model (in vivo) spontaneous rhythmic bladder contractions were induced by ligation of the urethra. In addition single bladder contractions were recorded during neurostimulation of the pelvic nerve. Spontaneous and electrically induced bladder contractions were sensitive to papaverine and isoprenaline i...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282425
更新日期:1992-01-01 00:00:00
abstract::Adherence of human prostate carcinoma (PC 3, DU 145), bladder (647 V, J 82) carcinoma and melanoma (RPMI-8252) cell lines to plastic and bovine endothelial monolayers (BEM) was tested in the presence of 0.5, 1, 5, 10, 20 IU of low-molecular-weight heparin (LMWH), unfractionated heparin (UFH) or saline as a control. Cu...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282848
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the characteristics of the renal arterial segment bleeding and assess the outcome of selective renal artery embolization (SRAE). METHODS:Data on 35 patients in whom SRAE was performed after percutaneous nephrolithotomy (PCNL) from January 2005 to December 2015 in our in...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000508797
更新日期:2020-01-01 00:00:00
abstract::Vesicovaginal fistula (VVF) is a quite rare complication of gynecological surgery. The first attempt to repair the fistulous tract offers the best opportunity for cure. We report the successful repair of VVF in 2 patients using a combined anterior vaginal approach and porcine dermal collagen grafting as interposition ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000176038
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:When feasible, the treatment for all-invasive bladder cancer is radical cystectomy. The aim of the present study was to analyze the prognostic difference, disease-specific survival rate, of muscle-invasive transitional cell cancer of the bladder (TCCB) for progressive invasive TCCB. PATIENTS...
journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
doi:10.1159/000107950
更新日期:2007-01-01 00:00:00