Abstract:
INTRODUCTION:Many epidemiological and experimental studies report a strong role of chemical carcinogens in the etiology of bladder cancer. However, involvement of trace elements in the tumorigenesis of transitional cell carcinoma of the bladder has been poorly investigated. The aim of this study was to examine the relationship between zinc, copper and bladder cancer. MATERIALS AND METHODS:Zinc and copper concentration and Cu/Zn ratio in two 36-sample series of bladder cancer tissue and sera from patients with this neoplasm were matched with those of the control group. The amount of trace elements in every tissue sample was determined using atomic absorption spectrometry. This was correlated with tumor stage. RESULTS:While the copper concentrations reached statistically higher values in the bladder cancer tissue, the zinc levels in the sera and bladder tissue of the patients with this carcinoma were substantially lower as compared to those of the control group. The serum Cu/Zn ratio was significantly higher in the bladder cancer group and this increase was greater in the patients with muscle-invasive neoplasm. CONCLUSIONS:The results obtained suggest a relationship between trace elements and the bladder cancer.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Golabek T,Darewicz B,Borawska M,Socha K,Markiewicz R,Kudelski Jdoi
10.1159/000341976subject
Has Abstractpub_date
2012-01-01 00:00:00pages
342-7issue
3eissn
0042-1138issn
1423-0399pii
000341976journal_volume
89pub_type
杂志文章abstract:OBJECTIVE:Our aim was to determine the safety and feasibility of catheter removal on the first morning after transurethral prostatectomy. METHODS:Fifty-four patients who underwent transurethral prostatectomy were included in a prospective study. The decision to remove the catheters on the first morning after surgery w...
journal_title:Urologia internationalis
pub_type: 杂志文章
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abstract:INTRODUCTION:We aimed to assess the outcome of free tube graft urethroplasty for single-stage repair of hypospadias with chordee in children. MATERIALS AND METHODS:We retrospectively evaluated a series of 56 patients (16 months to 9 years old, median 24 months) who underwent free graft urethroplasty for repair of hypo...
journal_title:Urologia internationalis
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abstract::A 63-year-old man underwent inguinal orchiectomy for painless enlargement of the left testis. The diagnosis of malignant gonadal stromal tumor was made on the basis of morphology and immunohistochemical studies. At computed tomography there was bulky retroperitoneal metastasis. The patient then underwent retroperitone...
journal_title:Urologia internationalis
pub_type: 杂志文章
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281298
更新日期:1988-01-01 00:00:00
abstract::Biopsies of 9 testicular tumors were examined for the presence of cytoplasmic receptor proteins for estrogens, progestins, androgens, and glucocorticoids. Using an arbitrary threshold value of 10 fmol/mg cytosol protein for a postive assay, only 1 of 9 tumors was estrogen-receptor positive. However, no receptor-specif...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281072
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journal_title:Urologia internationalis
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doi:10.1159/000078811
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000437442
更新日期:2018-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:Urologia internationalis
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journal_title:Urologia internationalis
pub_type: 杂志文章
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030429
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282181
更新日期:1991-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
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更新日期:2015-01-01 00:00:00
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journal_title:Urologia internationalis
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doi:10.1159/000075267
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pub_type: 杂志文章
doi:10.1159/000282023
更新日期:1990-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000074093
更新日期:2003-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1159/000320510
更新日期:2011-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章,评审
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更新日期:2012-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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更新日期:2008-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
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更新日期:2005-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析,评审
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更新日期:2015-01-01 00:00:00
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journal_title:Urologia internationalis
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更新日期:1992-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Urologia internationalis
pub_type: 杂志文章
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更新日期:1975-01-01 00:00:00