Abstract:
INTRODUCTION:The treatment of T1G3 bladder cancer is still a controversial issue. Nowadays, intravesical bacillus Calmette-Guérin (BCG) instillation is considered to be the treatment of choice for patients with high-grade superficial bladder tumour after transurethral resection of all visible tumour. The aim of this retrospective study was to determine the effects and results of this approach, recurrence and progression rates in patients with T1G3 superficial bladder tumours. MATERIALS AND METHODS:43 patients (28 male, 15 female; mean age 65.5 years, range 21-82) with T1G3 TCC (transitional cell carcinoma) bladder tumour underwent transurethral resection and subsequent intravesical BCG according to Morales protocol, in the period 1993-1998 at our institution. The mean follow-up period was 52.5 (range 30-96) months. RESULTS:After one or more initial courses of therapy, 33 patients were disease-free. Twelve patients (27.90%) had recurrent tumour after a median of 7 (range 3-46) months. After a second course of BCG treatment, 6 patients had no evidence of disease, 3 patients had progression and 3 had recurrence. Progression occurred in 7 (16.27%) patients after a median of 19 (range 3-43) months. Five patients underwent radical cystectomy and the remaining 2 underwent bladder-preserving therapies. Two patients died of TCC and 3 due to disease-unrelated conditions. CONCLUSION:Intravesical BCG instillation can be recommended as treatment modality for responders with T1G3 TCC bladder tumour. The benefit of the second course of intravesical BCG therapy has to be confirmed in further investigations.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Bogdanović J,Marusić G,Djozić J,Sekulić V,Budakov P,Dejanović N,Stojkov Jdoi
10.1159/000066121subject
Has Abstractpub_date
2002-01-01 00:00:00pages
263-5issue
4eissn
0042-1138issn
1423-0399pii
66121journal_volume
69pub_type
杂志文章abstract:AIMS:To study the effects of left gonadal vein ligation on semen parameters and venous hemodynamics of the testis. SUBJECTS AND METHODS:All male voluntary kidney donors who were scheduled to have left donor nephrectomy between March 2004 and February 2005, by either open or laparoscopic technique, were considered for ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000277603
更新日期:2010-01-01 00:00:00
abstract::Injuries of the penis are uncommon but represent urological emergencies. We report 3 cases of penile trauma illustrating the diversity of penile injury presentation. Radiological investigations are only mandatory if there is any suspicion of a urethral injury. Primary surgical approach is recommended in cases of penil...
journal_title:Urologia internationalis
pub_type: 杂志文章
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abstract::Extrarenal calyces are an extremely rare entity and only a few cases have been reported worldwide. We report a case with extrarenal calyces and give a brief review of the literature. Awareness of this rare entity can prevent inadvertent injury to the pelvicalyceal system during surgery. ...
journal_title:Urologia internationalis
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abstract:OBJECTIVES:Basic science studies of ureteral physiology and pathophysiology are commonly performed on animal ureters due to several limitations associated with human ureteral sampling. In this work we question whether animal ureters are good replicas of human ureteral behavior for pharmacological studies. MATERIALS AN...
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abstract::Membrane fluidity and lipid composition of rat testis in experimental bilateral cryptorchidism were studied. Membrane fluidity measured by fluorescence anisotropy of diphenylhexatriene decreased on the 3rd day of intraabdominal fixation, at an early stage of cryptorchidism. Lipid composition of testicular membrane was...
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282928
更新日期:1996-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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journal_title:Urologia internationalis
pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
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更新日期:2009-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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更新日期:2003-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
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更新日期:2005-01-01 00:00:00
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journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000508796
更新日期:2020-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1159/000438830
更新日期:2015-01-01 00:00:00
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更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:1986-01-01 00:00:00
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更新日期:2002-01-01 00:00:00
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更新日期:2020-01-01 00:00:00
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更新日期:2003-01-01 00:00:00
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